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  1. Book ; Online ; Thesis: Nachsorge nach radikaler vaginaler Trachelektomie – welche Probleme hat die Patientin, welche die Ärztin/der Arzt?

    Malik, Shazia [Verfasser]

    2022  

    Author's details Shazia Malik
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Medizinische Fakultät Charité - Universitätsmedizin Berlin
    Publishing place Berlin
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  2. Article ; Online: Management of mixed urinary incontinence: IUGA committee opinion.

    Jha, Swati / Jeppson, Peter C / Dokmeci, Fulya / Marquini, Gisele V / Sartori, Marair G F / Moalli, Pamela / Malik, Shazia A

    International urogynecology journal

    2024  Volume 35, Issue 2, Page(s) 291–301

    Abstract: Introduction and hypothesis: Mixed urinary incontinence (MUI) is defined by the International Urogynecology Association (IUGA) and International Continence Society as the complaint of involuntary leakage of urine associated with urgency and also with ... ...

    Abstract Introduction and hypothesis: Mixed urinary incontinence (MUI) is defined by the International Urogynecology Association (IUGA) and International Continence Society as the complaint of involuntary leakage of urine associated with urgency and also with exertion, effort, sneezing or coughing. It therefore implies the coexistence of both stress urinary incontinence (SUI) and urgency urinary incontinence (UUI). MUI is a heterogeneous diagnosis that requires an assessment of its individual components of SUI and UUI. Management requires an individualised approach to the symptom components. The aim of this review is to identify the assessment/investigations and management options for MUI.
    Methods: A working subcommittee from the IUGA Research & Development (R&D) Committee was created and volunteers invited from the IUGA membership. A literature review was performed to provide guidance focused on the recommended assessment and management of MUI. The document was then evaluated by the entire IUGA R&D Committee and IUGA Board of Directors and revisions made. The final document represents the IUGA R&D Committee Opinion.
    Results: The R&D Committee MUI opinion paper provides guidance on the assessment and management of women with MUI and summarises the evidence-based recommendations.
    Conclusions: Mixed urinary incontinence is a complex problem and successful management requires alleviation of both the stress and urge components. Care should be individualised based on patient preferences. Further research is needed to guide patients in setting goals and to determine which component of MUI to treat first. The evidence for many of the surgical/procedural treatment options for MUI are limited and needs to be explored in more detail.
    MeSH term(s) Humans ; Female ; Urinary Incontinence, Stress/complications ; Urinary Incontinence, Urge/diagnosis ; Urinary Incontinence, Urge/therapy ; Urinary Incontinence/diagnosis ; Urinary Incontinence/therapy ; Urinary Incontinence/complications ; Cough/complications
    Language English
    Publishing date 2024-01-22
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 1050631-7
    ISSN 1433-3023 ; 0937-3462
    ISSN (online) 1433-3023
    ISSN 0937-3462
    DOI 10.1007/s00192-023-05694-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Inflammatory cytokines associated with mild traumatic brain injury and clinical outcomes: a systematic review and meta-analysis.

    Malik, Shazia / Alnaji, Omar / Malik, Mahnoor / Gambale, Teresa / Farrokhyar, Forough / Rathbone, Michel P

    Frontiers in neurology

    2023  Volume 14, Page(s) 1123407

    Abstract: Mild traumatic brain injuries (mTBIs) trigger a neuroinflammatory response, which leads to perturbations in the levels of inflammatory cytokines, resulting in a distinctive profile. A systematic review and meta-analysis were conducted to synthesize data ... ...

    Abstract Mild traumatic brain injuries (mTBIs) trigger a neuroinflammatory response, which leads to perturbations in the levels of inflammatory cytokines, resulting in a distinctive profile. A systematic review and meta-analysis were conducted to synthesize data related to levels of inflammatory cytokines in patients with mTBI. The electronic databases EMBASE, MEDLINE, and PUBMED were searched from January 2014 to December 12, 2021. A total of 5,138 articles were screened using a systematic approach based on the PRISMA and R-AMSTAR guidelines. Of these articles, 174 were selected for full-text review and 26 were included in the final analysis. The results of this study demonstrate that within 24 hours, patients with mTBI have significantly higher levels of Interleukin-6 (IL-6), Interleukin-1 Receptor Antagonist (IL-1RA), and Interferon-γ (IFN-γ) in blood, compared to healthy controls in majority of the included studies. Similarly one week following the injury, patients with mTBI have higher circulatory levels of Monocyte Chemoattractant Protein-1/C-C Motif Chemokine Ligand 2 (MCP-1/CCL2), compared to healthy controls in majority of the included studies. The results of the meta-analysis also confirmed these findings by demonstrating significantly elevated blood levels of IL-6, MCP-1/CCL2, and Interleukin-1 beta (IL-1β) in the mTBI population compared to healthy controls (
    Language English
    Publishing date 2023-05-12
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2023.1123407
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Pharmacognostic characterization of Dicleptera chinensis by scanning electron microscopy, light microscopy, and analytical techniques.

    Sarfraz, Mehak / Alam, Fiaz / Din, Kinza Muhammad / Malik, Shazia / Quddoos, Atifa

    Microscopy research and technique

    2023  Volume 87, Issue 2, Page(s) 279–290

    Abstract: Dicleptera chinensis J. (Acanthaceae) has been employed in traditional medicinal systems for treating various ailments. It has been used as an anti-inflammatory, wound healing, diuretic, and detoxifying agent in different regions of the world. This study ...

    Abstract Dicleptera chinensis J. (Acanthaceae) has been employed in traditional medicinal systems for treating various ailments. It has been used as an anti-inflammatory, wound healing, diuretic, and detoxifying agent in different regions of the world. This study determines several pharmacognostic standards, which are useful to ensure safety, efficacy, and purity of D. chinensis. Different parts of the plant were examined through a scanning electron microscope and light microscope, and cross-section images revealed several useful botanical features of the plant. The color, size, odor, shape, and surface characteristics of plant parts were also examined macroscopically. Pharmacognostic standardization parameters including ash values, loss on drying, swelling index, hemolytic index, and foaming index were determined in accordance with WHO guidelines. Heavy metal analysis was executed through atomic absorption spectrophotometer which depicted the presence of heavy metals and trace elements within the acceptable range. Qualitative phytochemical tests for alkaloids, flavonoids, saponins, glycosides, tannins, carbohydrates, lipids, protein, and so forth of plant extract were also performed, which showed the valuable amount of these phytochemicals useful for medicinal purposes. Preliminary phytochemical tests provide an indication for major phytoconstituents classes present in the plant. These quantitative and qualitative microscopic features are helpful in establishing the pharmacopeia standards of plant. Assessment of various pharmacognostic features such as morphology of various plant parts explained along with physicochemical and phytochemical analysis could be very helpful for future research. RESEARCH HIGHLIGHTS: Pharmacognostic standardization is employed as reported evidence for correct identification of D. chinensis. Structures identified by scanning electron microscopy and light microscopy serve as diagnostic features of plant. Important secondary metabolites present in the plant suggest the need for further exploration through advanced metabolomics and other analytical techniques.
    MeSH term(s) Microscopy, Electron, Scanning ; Pharmacognosy/methods ; Plant Leaves/anatomy & histology ; Plant Extracts/chemistry ; Phytochemicals/analysis
    Chemical Substances Plant Extracts ; Phytochemicals
    Language English
    Publishing date 2023-09-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1099714-3
    ISSN 1097-0029 ; 1059-910X
    ISSN (online) 1097-0029
    ISSN 1059-910X
    DOI 10.1002/jemt.24429
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Satisfaction Level Of Patients With Services Provided In Dental Outpatient Department Of Rawal Institute Of Health Sciences, Islamabad.

    Abbasi, Abeera Faraz / Noor, Noman / Malik, Shazia / Kamran, Muhammad Farooq

    Journal of Ayub Medical College, Abbottabad : JAMC

    2021  Volume 33, Issue 3, Page(s) 467–470

    Abstract: Background: Patient satisfaction reflects the level of ease that the patient experiences having used a service. It can identify the gap between the actual experience of the services versus expected. Patients' satisfaction has been widely used in the lay ...

    Abstract Background: Patient satisfaction reflects the level of ease that the patient experiences having used a service. It can identify the gap between the actual experience of the services versus expected. Patients' satisfaction has been widely used in the lay measurement of quality of health service. The purpose of this study was to examine the structural relationships between out-patient satisfaction and service quality extent.
    Methods: This was a cross sectional study carried out on 196 conveniently selected patients from 5 July to 5 September 2018 at the general outpatient department of Rawal institute of Health sciences Islamabad. Parameters used to measure the satisfaction levels of the presenting patients were: ease of access, waiting time for the patients, patient-provider communication, patient-provider relationship, hospital administration, and general hospital ambiance and environment.
    Results: The overall satisfaction score of the patients under consideration was 74.48%. Specifically, the respondents were highly satisfied with due attention given by the doctors (80%). Around (74%) said that the presenting doctors addressed them with a very humble and polite attitude; 80% said that they would recommend this hospital to their contacts. While 56% of the patients said they had to wait for longer time for the doctor.
    Conclusions: This study reveals that the overall level of patients' satisfaction with the provided services was satisfactory. Patients were highly satisfied with attention given by the presenting doctors. The only major point for dissatisfaction was the waiting time and the explanation of the procedure.
    MeSH term(s) Communication ; Cross-Sectional Studies ; Humans ; Outpatients ; Patient Satisfaction ; Personal Satisfaction
    Language English
    Publishing date 2021-09-06
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 2192473-9
    ISSN 1819-2718 ; 1025-9589
    ISSN (online) 1819-2718
    ISSN 1025-9589
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Correlation between Mild Traumatic Brain Injury-Induced Inflammatory Cytokines and Emotional Symptom Traits: A Systematic Review.

    Malik, Shazia / Alnaji, Omar / Malik, Mahnoor / Gambale, Teresa / Rathbone, Michel Piers

    Brain sciences

    2022  Volume 12, Issue 1

    Abstract: Both mild traumatic brain injuries (mTBI) and systemic injuries trigger a transient neuroinflammatory response that result in similar clinical outcome. The ensuing physical, cognitive, and emotional symptoms fail to subside in approximately 15-20% of the ...

    Abstract Both mild traumatic brain injuries (mTBI) and systemic injuries trigger a transient neuroinflammatory response that result in similar clinical outcome. The ensuing physical, cognitive, and emotional symptoms fail to subside in approximately 15-20% of the concussed population. Emotional impairments, particularly depression, anxiety, and post-traumatic stress disorder (PTSD), are commonly associated with poor recovery following mTBI. These emotional impairments also have a significant neuroinflammatory component. We hypothesized that the inflammatory cytokines seen in mTBI patients with emotional symptoms would coincide with those commonly seen in patients with emotional symptoms without mTBI. A systematic review was conducted to identify the most common neuroinflammatory cytokines in the mTBI population with psychological symptoms (depression, anxiety, PTSD). The electronic databases EMBASE, MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL), PUBMED, and PSYCINFO were searched from data inception to 31 August 2021. A systematic screening approach was employed from screening to data analysis. A total of 994 articles were screened, 108 were selected for full article review, and 8 were selected for data analysis. The included studies consisted of 875 patients of which 81.3% were male. The mean sample size of patients with at least one mTBI was 73.8 ± 70.3 (range, 9-213), with a mean age of 33.9 ± 4.8 years. The most common cytokines associated with poor psychological outcomes involving PTSD and/or depression in the chronic mTBI population were IL-6, TNFα, IL-10, and CRP.
    Language English
    Publishing date 2022-01-12
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci12010102
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Effects of Pilates Exercises on Core Stability After Recovery from COVID-19: A Randomized Controlled Trial.

    Amin, Wafaa Mahmoud / Ali, Olfat Ibrahim / Malik, Shazia / Draj, Suhair Asous I / Masoud, Fatima Ahmed M / Sohel, Amal Mohammed I / Al Amer, Asayil Mari / Khurayzi, Rasmiah Hassan H / Ahmed, Mohamed M

    Journal of multidisciplinary healthcare

    2024  Volume 17, Page(s) 753–763

    Abstract: Purpose: The primary objective was to investigate the effects of Pilates exercises on CS, and the secondary objective was to assess static trunk balance after recovery from COVID-19.: Patients and methods: 145 recovered COVID-19 university students ... ...

    Abstract Purpose: The primary objective was to investigate the effects of Pilates exercises on CS, and the secondary objective was to assess static trunk balance after recovery from COVID-19.
    Patients and methods: 145 recovered COVID-19 university students between the ages of 19 and 25 participated in this single-blinded, randomized controlled trial study. The participants were divided into a Pilates group and a control group, each of which received a home exercise program. Core muscle endurance was measured using the five basic endurance tests and static balance using the Prokin system with open eyes (OE) and closed eyes (CE) at baseline and after three months of treatment.
    Results: All measured parameters showed improvement within the groups after treatment. Group comparison revealed a significant increase in the Pilates group in all core endurance tests (P<0.001). The Prokin system results showed improvement in the Pilates group after treatment, while perimeter with OE, CE, and ellipse area with EC decreased (P<0.001), but there was no significant difference in ellipse with OE between the groups.
    Conclusion: Pilates exercises positively improved core muscle endurance and trunk balance in people infected with COVID-19, which will be reflected in their quality of movement patterns and quality of life.
    Language English
    Publishing date 2024-02-20
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2453343-9
    ISSN 1178-2390
    ISSN 1178-2390
    DOI 10.2147/JMDH.S453050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Kinesio Taping Increases Peak Torque of Quadriceps Muscle After Arthroscopic Meniscectomy, Double-Blinded RCT.

    Ahmed, Mohamed M / Zaino, Mohammad / Moustafa, Mahmoud / Alajam, Ramzi Abdu / Alameer, Abdulaziz H / Morsy, Walaa E / Fayed, Esraa Mohammed / Malik, Shazia / Amin, Wafaa Mahmoud

    International journal of general medicine

    2024  Volume 17, Page(s) 1897–1908

    Abstract: Purpose: This study was conducted to release the debate and examine the short-term impact of KT on the quadriceps muscle following arthroscopic surgery for partial meniscectomy.: Patients and methods: As part of a double-blind, randomized controlled ... ...

    Abstract Purpose: This study was conducted to release the debate and examine the short-term impact of KT on the quadriceps muscle following arthroscopic surgery for partial meniscectomy.
    Patients and methods: As part of a double-blind, randomized controlled trial, 40 people who had an arthroscopic partial meniscectomy (APM) were randomly put into two groups, A and B. Group A received Kinesio tape (KT) for the superficial heads of the quadriceps muscle, while group B received placebo KTk. After 10 minutes of KT application, the peak torque of both groups was measured using a Biodex isokinetic dynamometer.
    Results: Peak torque showed a significant increase in group A in comparison with group B during angular velocity 60◦/Sec. (F (1, 130) = 58.9, p <0.001, ƞ2 =0.31) and during angular velocity 180◦/Sec. (F (1, 38) = 25.0, p <0.001, ƞ2 =0.40).
    Conclusion: After APM, individuals experienced an immediate and significant improvement in the quadriceps' peak torque following KT application to the Rectus femoris, Vastus medialis, and Vastus lateralis muscles from origin to insertion.
    Language English
    Publishing date 2024-05-06
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2452220-X
    ISSN 1178-7074
    ISSN 1178-7074
    DOI 10.2147/IJGM.S463753
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: E-module as an emergency-innovated learning source during the Covid-19 outbreak

    Purnamasari, Niken / Siswanto, Siswanto / Malik, Shazia

    Psychology, Evaluation, and Technology in Educational Research; Vol 3, No; 1-8 ; 2622-5506

    2020  Volume 1

    Abstract: The COVID-19 pandemic has hugely changed various human activities. This "silent-killer" pandemic attacks almost every single aspect of life in this entire world. In this case, the writer will focus on the education sector as one of the most damaged ... ...

    Abstract The COVID-19 pandemic has hugely changed various human activities. This "silent-killer" pandemic attacks almost every single aspect of life in this entire world. In this case, the writer will focus on the education sector as one of the most damaged fields by the pandemic. Every single of its elements has to be quickly adapted to the situation caused by the COVID-19 attack. Stakeholders are continuing hard to formulate the adaptation that can be taken quickly as the most effective way among the uncertain situation. Shortly, regarding the physical distancing campaigned by the most governments, online learning is then considered as the most possible way to keep the learning process going with all its strengths and weaknesses. In accordance with the background of the situation, the writer through this study purposed to determine the effectiveness of e-modules as the emergency innovative learning sources in the middle of this COVID-19 outbreak. Online learning is claimed as an effective solution to keep learning to avoid mass gathering that possibly causes the virus to spread at schools. E-modules belong to interactive teaching sources that are capable to facilitate student to learn independently. They still have chances to learn with interesting, practical, and online-accessible to pursue the learning outcomes as good as possible in term of the emergency self-learning process. To find out the improvement in students learning outcomes after using the e-module through the online learning process, the data analysis in this study was conducted using a paired sample t-test. At last, the results showed that student learning outcomes could be maintained and even improved after the use of the e-module as an emergency innovative learning source during the COVID-19 outbreak.
    Keywords E-Module ; Emergency Learning ; Online Learning ; Learning Source ; COVID-19 Outbreak ; covid19
    Subject code 370
    Language English
    Publishing date 2020-09-10
    Publisher Research and Social Study Institute
    Publishing country id
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Assessment of Risk Factors and the Relationship between Hypothyroidism with Hypertension in Diabetes Mellitus Patients: A Cross-Sectional Community-Based Study.

    Shaphe, Mohammad Abu / Alshehri, Mohammed M / Alfaifi, Bushra / Aljahni, Mohammed A / Esht, Vandana / Malik, Shazia / Bautista, Marissa J / Alqahtani, Abdulfattah S / Ahmad, Ausaf / Khan, Ashfaque / Aafreen, Aafreen / Khan, Abdur Raheem

    Journal of personalized medicine

    2023  Volume 13, Issue 8

    Abstract: 1) Background: hypertension (HTN) and diabetes mellitus (DM) represent two widely noncommunicable diseases that are prevalent globally, and they often correlate with chronic health issues. There has been an acknowledged connection between diabetes, ... ...

    Abstract (1) Background: hypertension (HTN) and diabetes mellitus (DM) represent two widely noncommunicable diseases that are prevalent globally, and they often correlate with chronic health issues. There has been an acknowledged connection between diabetes, hypertension, and hypothyroidism for quite some time. However, the extent of thyroid dysfunction among the diabetic population is not uniform and significantly differs across different research studies. This study was conducted with the objective of identifying the risk factors associated with hypothyroidism as well as assessing the relationship between hypothyroidism and hypertension in patients with diabetes. (2) Materials and Methods: Participants aged 18 years and above were included in this study, while pregnant women were excluded. Trained health professionals measured sociodemographic, behavioural, food practices, and anthropometric information about the participants. Each respondent sought medical advice regarding their health, and a face-to-face interview enabled them to express concern about the likelihood of being diagnosed with diabetes mellitus and hypertension. (3) Results: The study encompassed 640 participants, with an average age of 49.20 ± 13.0 years. Among these participants, 65.5% were female, and 34.5% were male. Of the total, 31.25% were diagnosed with diabetes mellitus, and 18.75% had hypertension. Interestingly, co-occurrence of both conditions was observed in 9.68% of the population. A comparison of thyroid function and indicators of blood sugar levels yielded consistent results across the different patient groups. Specifically, for diabetes mellitus (DM) patients, the average levels were 3.4 ± 9.8 pg/mL for fT3, 0.9 ± 0.7 ng/dL for fT4, 3.3 ± 6.2 μiU/mL for TSH, 153.1 ± 68.0 mg/dL for fasting plasma glucose (FPG), 213.2 ± 97.2 mg/dL for postprandial glucose (PPG), and 8.3 ± 3.2% for HbA1c. (4) Conclusion: It is concluded that patients with hypertension had a significant prevalence of diabetes mellitus. Subclinical hypothyroid subjects must be frequently screened for hypertension. Of 120 individuals with hypertension, 45 (37.5%) were also diagnosed with diabetes. This co-occurrence was significantly higher in subjects aged over 50 years (26.7%), in the lower socio-economic class (18.5%), and among those who were married (14.7%). Additionally, patients with hypertension exhibited a high prevalence of diabetes across different educational backgrounds and occupations, with the highest prevalence among postgraduates (37.5%) and professionals (24.0%), respectively. These findings highlight the need for an integrated approach to the management of hypertension and diabetes, particularly in high-risk demographics.
    Language English
    Publishing date 2023-08-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662248-8
    ISSN 2075-4426
    ISSN 2075-4426
    DOI 10.3390/jpm13081231
    Database MEDical Literature Analysis and Retrieval System OnLINE

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