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  1. Article ; Online: Trillium govanianum Wall. Ex. Royle rhizomes extract-medicated silver nanoparticles and their antimicrobial activity

    Uz-Zaman Khaleeq / Bakht Jehan / Malikovna Bates Kudaibergenova / Elsharkawy Eman R. / Khalil Anees Ahmed / Bawazeer Saud / Rauf Abdur

    Green Processing and Synthesis, Vol 9, Iss 1, Pp 503-

    2020  Volume 514

    Abstract: Synthesis of nanoparticles is a fast-growing area of interest in the current development in science and technology. Nanoparticles are also used in biomedical applications. Green synthesis of nanoparticles is an environmental friendly and cost-effective ... ...

    Abstract Synthesis of nanoparticles is a fast-growing area of interest in the current development in science and technology. Nanoparticles are also used in biomedical applications. Green synthesis of nanoparticles is an environmental friendly and cost-effective technique. Trillium govanianum Wall. Ex. Royle crude extract was used for the eco-friendly genesis of silver nanoparticles (AgNPs). Aromatic amines were the functional groups involved in the bio-fabrication and synthesis of the AgNPs. The production of AgNPs was established by the appearance of brown color. The manufactured AgNPs were characterized by UV-Vis spectrophotometer, X-ray diffractometer, and FTIR spectrophotometer. AgNPs were face-centered cubic in nature with an average size of 9.99 nm. The produced AgNPs (18 µL disc−1) showed substantial antibacterial (53.74, 52.75, 51.61, 43.00, 36.84, and 36.84%) and antifungal (54.05, 42.11, 41.10, 40.85, 30.55, and 29.73%) potential against the tested bacterial (X. campestris, P. aeruginosa, S. aureus, E. coli, B. subtilis, and K. pneumoniae) and fungal (A. alternaria, Paecilomyces, C. albicans, Curvularia, A. niger, and Rhizopus) strains, respectively.
    Keywords trillium govanianum ; agnps ; uv ; ft-ir ; x-ray diffractometer ; Chemistry ; QD1-999
    Subject code 620
    Language English
    Publishing date 2020-09-01T00:00:00Z
    Publisher De Gruyter
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Green synthesis, in vivo and in vitro pharmacological studies of Tamarindus indica based gold nanoparticles.

    Ullah, Ubaid / Rauf, Abdur / El-Sharkawy, Eman / Khan, Farhan Ahmed / Khan, Ajmal / Bukhari, Syed Majid / Bawazeer, Saud / Mabkhot, Yahia Naseer / Malikovna, Bates Kudaibergenova / Kazhybayeva, Galiya / Shariati, Mohammad Ali / Thiruvengadam, Muthu

    Bioprocess and biosystems engineering

    2021  Volume 44, Issue 6, Page(s) 1185–1192

    Abstract: The current investigation aims to synthesize gold nanoparticles (AuNPs) from aqueous extract of Tamarindus indica and to evaluate the in vitro anti-bacterial and in vivo sedative and anelgescic activities of crude extract as well as synthesized AuNPs. ... ...

    Abstract The current investigation aims to synthesize gold nanoparticles (AuNPs) from aqueous extract of Tamarindus indica and to evaluate the in vitro anti-bacterial and in vivo sedative and anelgescic activities of crude extract as well as synthesized AuNPs. Several methods have been reported to synthesize AuNPs; however, most of them were not ecofriendly. In the present study, the green synthesis of AuNPs has been carried out. Using the green synthesis method, AuNPs of T. indica were synthesized at room temperature (25 °C) by mixing 5 mL of HAuCl
    MeSH term(s) Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Bacteria/growth & development ; Gold/chemistry ; Gold/pharmacology ; Green Chemistry Technology ; Metal Nanoparticles/chemistry ; Plant Extracts/chemistry ; Seeds/chemistry ; Tamarindus/chemistry
    Chemical Substances Anti-Bacterial Agents ; Plant Extracts ; Gold (7440-57-5)
    Language English
    Publishing date 2021-02-13
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1476357-6
    ISSN 1615-7605 ; 1432-0797 ; 1615-7591
    ISSN (online) 1615-7605 ; 1432-0797
    ISSN 1615-7591
    DOI 10.1007/s00449-020-02500-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Green synthesis and biomedicinal applications of silver and gold nanoparticles functionalized with methanolic extract of

    Rauf, Abdur / Ahmad, Touqeer / Khan, Ajmal / Maryam / Uddin, Ghias / Ahmad, Bashir / Mabkhot, Yahia Nasser / Bawazeer, Sami / Riaz, Nadia / Malikovna, Bates Kudaibergenova / Almarhoon, Zainab M / Al-Harrasi, Ahmed

    Artificial cells, nanomedicine, and biotechnology

    2021  Volume 49, Issue 1, Page(s) 194–203

    Abstract: This study deals with facile and rapid synthesis of silver nanoparticles (AgNPs) and Gold nanoparticles (AuNPs) ... ...

    Abstract This study deals with facile and rapid synthesis of silver nanoparticles (AgNPs) and Gold nanoparticles (AuNPs) using
    MeSH term(s) Animals ; Biocompatible Materials/chemical synthesis ; Biocompatible Materials/chemistry ; Biocompatible Materials/pharmacology ; Chemistry Techniques, Synthetic ; Gold ; Green Chemistry Technology ; Mentha/chemistry ; Metal Nanoparticles/chemistry ; Methanomicrobiaceae/chemistry ; Mice ; Plant Extracts/chemistry ; Silver/chemistry
    Chemical Substances Biocompatible Materials ; Plant Extracts ; Silver (3M4G523W1G) ; Gold (7440-57-5)
    Language English
    Publishing date 2021-02-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 2723095-8
    ISSN 2169-141X ; 2169-1401
    ISSN (online) 2169-141X
    ISSN 2169-1401
    DOI 10.1080/21691401.2021.1890099
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Green synthesis, in vivo and in vitro pharmacological studies of Tamarindus indica based gold nanoparticles

    Ullah, Ubaid / Rauf, Abdur / El-Sharkawy , Eman / Khan, Farhan Ahmed / Khan, Ajmal / Bukhari, Syed Majid / Bawazeer, Saud / Mabkhot, Yahia Naseer / Malikovna, Bates Kudaibergenova / Kazhybayeva, Galiya / Shariati, Mohammad Ali / Thiruvengadam, Muthu

    Bioprocess and biosystems engineering. 2021 June, v. 44, no. 6

    2021  

    Abstract: The current investigation aims to synthesize gold nanoparticles (AuNPs) from aqueous extract of Tamarindus indica and to evaluate the in vitro anti-bacterial and in vivo sedative and anelgescic activities of crude extract as well as synthesized AuNPs. ... ...

    Abstract The current investigation aims to synthesize gold nanoparticles (AuNPs) from aqueous extract of Tamarindus indica and to evaluate the in vitro anti-bacterial and in vivo sedative and anelgescic activities of crude extract as well as synthesized AuNPs. Several methods have been reported to synthesize AuNPs; however, most of them were not ecofriendly. In the present study, the green synthesis of AuNPs has been carried out. Using the green synthesis method, AuNPs of T. indica were synthesized at room temperature (25 °C) by mixing 5 mL of HAuCl₄ (1 mM) with 1 mL of T. indica seed extract solution. This extract solution was prepared by taking 5 gm dry seeds in 100 mL of double deionized water with continuous stirring for up to 24 h at 80 °C. The stability of AuNPs was confirmed with the help of relevant experimental techniques including ultraviolet–visible (UV/Vis) showing maximum absorbance at 535–540 nm, Fourier transform infrared showing a broad signal at 3464 cm⁻¹ which can be attributed to either amide or hydroxyl functionalities and atomic force microscopy analysis showed that the biomaterial surrounding AuNPs was agglomerated which proves the formation of discrete nanostructutres. These AuNPs have been evaluated for their antibacterial potential. The results revealed good antibacterial activity of the samples against. Klebsiella pneumonia, Bacillus subtilis and Staphylococcus epidermidis with 10–12 mm zone of inhibition range. The AuNPs were also found stable at high temperature, over a range of pH and in 1 mM salt solution. Moreover, the crude extract and respective AuNPs also exhibited interesting sedative and analgesic activities. Hence, we focused on phytochemicals-mediated synthesis of AuNPs considered as greatest attention in the treatment of anti-bacterial, analgesic, and sedative.
    Keywords Bacillus subtilis ; Fourier transform infrared spectroscopy ; Klebsiella pneumoniae ; Staphylococcus epidermidis ; Tamarindus indica ; absorbance ; ambient temperature ; analgesics ; antibacterial properties ; atomic force microscopy ; biocompatible materials ; bioprocessing ; nanogold ; pH ; sedatives ; seed extracts
    Language English
    Dates of publication 2021-06
    Size p. 1185-1192.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 1476357-6
    ISSN 1432-0797 ; 1615-7605 ; 1615-7591
    ISSN (online) 1432-0797 ; 1615-7605
    ISSN 1615-7591
    DOI 10.1007/s00449-020-02500-8
    Database NAL-Catalogue (AGRICOLA)

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