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  1. Article: Abdominoscrotal Lymphangioma Masquerading as a Communicating Hydrocele: A Case Report.

    AlRashed, Ahmed / Gazali, Zarine / Malladi, Vijay Kumar / Singal, Arbinder Kumar

    The Gulf journal of oncology

    2020  Volume 1, Issue 32, Page(s) 63–65

    Abstract: A 5-year old boy presented with a picture of communicating hydrocele and was discovered to have an abdominoscrotal lymphangioma after undergoing hydrocele surgery. Upon initial presentation the lymphangioma was missed and the child underwent inguinal ... ...

    Abstract A 5-year old boy presented with a picture of communicating hydrocele and was discovered to have an abdominoscrotal lymphangioma after undergoing hydrocele surgery. Upon initial presentation the lymphangioma was missed and the child underwent inguinal approach surgery for hydrocele. The lymphangioma was then noticed as an abdominal lump due to a rapid increase in size within 1 week following the hydrocele surgery. The sudden enlargement of the lymphangioma was due to intra-cystic hemorrhage post-operatively. The lymphangioma was then completely excised with no recurrence noted after 1 year of follow up. This is a rare case of a retroperitoneal, abdominoscrotal lymphangioma masquerading as a communicating hydrocele. Keywords: Communicating Hydrocele, Abdominoscrotal lymphangioma, Scrotal Swelling.
    MeSH term(s) Child, Preschool ; Humans ; Lymphangioma/diagnosis ; Lymphangioma/pathology ; Male ; Testicular Hydrocele/diagnosis ; Testicular Hydrocele/pathology
    Language English
    Publishing date 2020-05-12
    Publishing country Kuwait
    Document type Case Reports ; Journal Article
    ISSN 2078-2101
    ISSN 2078-2101
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Variant morphology in multiple myeloma.

    Koduri, Prasad R / Gowrishankar, Swarnalata / Malladi, Vijay Kumar

    Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion

    2013  Volume 30, Issue Suppl 1, Page(s) 86–87

    Abstract: A 45-year-old man presented to the clinic with the chief complaints of low back pain, marked weight loss, and pallor of 2 months duration. He was found to have severe normocytic anemia with leukoerythroblastosis. Bone marrow aspirate resulted in a dry ... ...

    Abstract A 45-year-old man presented to the clinic with the chief complaints of low back pain, marked weight loss, and pallor of 2 months duration. He was found to have severe normocytic anemia with leukoerythroblastosis. Bone marrow aspirate resulted in a dry tap. Marrow trephine biopsy showed findings initially interpreted as poorly differentiated carcinoma involving marrow. Immunohistochemistry and protein studies established a diagnosis of IgG Kappa multiple myeloma. Correlation of marrow biopsy findings with clinical, radiological and immunological data remain an essential part of the diagnostic evaluation of multiple myeloma.
    Language English
    Publishing date 2013-04-26
    Publishing country India
    Document type Case Reports
    ZDB-ID 2422370-0
    ISSN 0974-0449 ; 0971-4502
    ISSN (online) 0974-0449
    ISSN 0971-4502
    DOI 10.1007/s12288-013-0259-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A Common SNP of IL-10 (-1082A/G) is Associated With Increased Risk of Premenopausal Breast Cancer in South Indian Women

    Cingeetham Vinod / Akka Jyothy / Malladi Vijay kumar / Ramaiyer Raghu Raman / Pratibha Nallari / Ananthapur Venkateshwari

    Iranian Journal of Cancer Prevention, Vol 8, Iss

    2015  Volume 4

    Abstract: Background: Evading the immune destruction and angiogenesis has been the two hallmarks of cancer. Interleukin-10 (IL-10) is a cytokine with immune suppressing (pro-tumorigenic) and anti-angiogenic (anti-tumorigenic) properties, thus making the role of IL- ...

    Abstract Background: Evading the immune destruction and angiogenesis has been the two hallmarks of cancer. Interleukin-10 (IL-10) is a cytokine with immune suppressing (pro-tumorigenic) and anti-angiogenic (anti-tumorigenic) properties, thus making the role of IL-10 in tumorigenesis enigmatic. Previous studies have suggested a critical role of IL10 altered expression in complex process of tumor-microenvironment, co-evolution and tumorigenesis. Objectives: Evaluating the role of IL10 (-1082A/G) gene promoter polymorphism in breast cancer patients from South India. Patients and Methods: A case-control study was conducted with a total of 285 individuals, these include 125 histologically confirmed breast cancer patients and 160 age and sex matched controls. Genotypes were determined by allele-specific polymerase chain reaction (AS-PCR), followed by agarose gel electrophoresis. Statistical analysis was done to test the significance of results obtained. Results: Statistical analysis revealed that AA genotype of the Il-10 -1082A/G polymorphism is significantly associated with breast cancer (AA vs. AG: χ2 = 14.46, P = 0.0001432, OR = 2.854, 95% CI = 1.68 - 4.849). Up on stratifying subjects based on cancer stage, age at onset, menopausal status, AA genotype has associated with all the sub groups, except for post-menopausal women. There was no significant association which was observed with respected to hormonal status (ER, PR) and Her2/neu status. Conclusions: The present study suggests that IL-10 AA genotype as a risk factor in the etiology of breast cancer in the South Indian population.
    Keywords Medicine ; R ; Internal medicine ; RC31-1245 ; Neoplasms. Tumors. Oncology. Including cancer and carcinogens ; RC254-282
    Subject code 616 ; 610
    Publishing date 2015-08-01T00:00:00Z
    Publisher Shahid Beheshti University of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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