Article ; Online: What Should Be the Topics of a Prospective Study on Ovarian Masses in Children?-Results of a Multicenter Retrospective Study and a Scoping Literature Review.
Current oncology (Toronto, Ont.)
2022 Volume 29, Issue 3, Page(s) 1488–1500
Abstract: Purpose: to determine management problems of ovarian masses in girls in order to form a baseline for prospective randomized studies of the established topics and quality improvement of our management.: Materials and methods: We performed a national ... ...
Abstract | Purpose: to determine management problems of ovarian masses in girls in order to form a baseline for prospective randomized studies of the established topics and quality improvement of our management. Materials and methods: We performed a national analysis of clinical aspects of ovarian masses in girls operated on in Poland, analyzed retrospectively medical files of all consecutive patients aged 0-18 who underwent surgeries for ovarian lesions between 2012 and 2017 at 17 pediatric surgical departments and complemented the analysis with a scoping review of a recent primary research related to ovarian masses in children. Results: The study group comprised 595 patients. Forty-four (7.39%) girls were diagnosed with malignant tumors. The overall preservation rate was 64.54%. The analysis revealed that positive tumor markers (OR = 10.3), lesions larger than 6 cm (OR = 4.17) and solid mass on ultrasound examination (OR = 5.34) are interdependent variables differentiating malignant tumors from non-malignant lesions (X42 = 79.1; Conclusions: We have developed an overview of the field with the emphasis on the local environment. Our next step is a multi-institutional prospective study of a quality improvement project implementation based on the obtained knowledge. |
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MeSH term(s) | Biomarkers, Tumor ; Child ; Female ; Humans ; Ovarian Cysts/diagnosis ; Ovarian Cysts/surgery ; Ovarian Neoplasms/diagnosis ; Ovarian Neoplasms/surgery ; Prospective Studies ; Retrospective Studies |
Chemical Substances | Biomarkers, Tumor |
Language | English |
Publishing date | 2022-02-28 |
Publishing country | Switzerland |
Document type | Journal Article ; Multicenter Study |
ZDB-ID | 1236972-x |
ISSN | 1718-7729 ; 1198-0052 |
ISSN (online) | 1718-7729 |
ISSN | 1198-0052 |
DOI | 10.3390/curroncol29030125 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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