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  1. Article ; Online: In the right place at the right time: ROS and Ca

    Mammucari, Cristina

    Cell calcium

    2021  Volume 95, Page(s) 102354

    Abstract: ... Both ... ...

    Abstract Both Ca
    Language English
    Publishing date 2021-02-06
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 757687-0
    ISSN 1532-1991 ; 0143-4160
    ISSN (online) 1532-1991
    ISSN 0143-4160
    DOI 10.1016/j.ceca.2021.102354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1596: Show issues Location:
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  2. Article ; Online: Ex Vivo Measurements of Ca

    Gherardi, Gaia / Mammucari, Cristina

    Methods in molecular biology (Clifton, N.J.)

    2019  Volume 1925, Page(s) 103–109

    Abstract: We report a method for ex vivo measurements of ... ...

    Abstract We report a method for ex vivo measurements of Ca
    MeSH term(s) Animals ; Calcium/analysis ; Calcium/metabolism ; Cytosol/metabolism ; Electroporation/methods ; Mice ; Microscopy/methods ; Mitochondria, Muscle/metabolism ; Molecular Probes/genetics ; Molecular Probes/metabolism ; Muscle Fibers, Skeletal/cytology ; Muscle Fibers, Skeletal/metabolism ; Optical Imaging/methods ; Plasmids/genetics ; Plasmids/metabolism ; Transfection/methods
    Chemical Substances Molecular Probes ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2019-01-23
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-4939-9018-4_9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The mitochondrial calcium homeostasis orchestra plays its symphony: Skeletal muscle is the guest of honor.

    Gherardi, Gaia / De Mario, Agnese / Mammucari, Cristina

    International review of cell and molecular biology

    2021  Volume 362, Page(s) 209–259

    Abstract: Skeletal muscle mitochondria are placed in close proximity of the sarcoplasmic reticulum (SR), the main intracellular ... ...

    Abstract Skeletal muscle mitochondria are placed in close proximity of the sarcoplasmic reticulum (SR), the main intracellular Ca
    MeSH term(s) Animals ; Calcium/metabolism ; Calcium Channels/metabolism ; Homeostasis ; Humans ; Mitochondria/metabolism ; Muscle, Skeletal/metabolism ; Reactive Oxygen Species/metabolism
    Chemical Substances Calcium Channels ; Reactive Oxygen Species ; mitochondrial calcium uniporter ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2021-05-20
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2427220-6
    ISSN 1937-6448 ; 0074-7696
    ISSN 1937-6448 ; 0074-7696
    DOI 10.1016/bs.ircmb.2021.03.005
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    Uc I Zs.317: Show issues Location:
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  4. Article ; Online: The mitochondrial calcium uniporter complex-A play in five acts.

    De Mario, Agnese / D'Angelo, Donato / Zanotti, Giuseppe / Raffaello, Anna / Mammucari, Cristina

    Cell calcium

    2023  Volume 112, Page(s) 102720

    Abstract: Mitochondrial ... ...

    Abstract Mitochondrial Ca
    MeSH term(s) Mitochondrial Membranes/metabolism ; Calcium/metabolism ; Mitochondria/metabolism ; Calcium Channels/metabolism
    Chemical Substances mitochondrial calcium uniporter ; Calcium (SY7Q814VUP) ; Calcium Channels
    Language English
    Publishing date 2023-03-24
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 757687-0
    ISSN 1532-1991 ; 0143-4160
    ISSN (online) 1532-1991
    ISSN 0143-4160
    DOI 10.1016/j.ceca.2023.102720
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1596: Show issues Location:
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  5. Article ; Online: Mitochondrial Ca

    De Mario, Agnese / Trevellin, Elisabetta / Piazza, Ilaria / Vindigni, Vincenzo / Foletto, Mirto / Rizzuto, Rosario / Vettor, Roberto / Mammucari, Cristina

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 8469

    Abstract: Obesity is associated with increased risk and worse prognosis of many tumours including those of the breast and of the esophagus. Adipokines released from the peritumoural adipose tissue promote the metastatic potential of cancer cells, suggesting the ... ...

    Abstract Obesity is associated with increased risk and worse prognosis of many tumours including those of the breast and of the esophagus. Adipokines released from the peritumoural adipose tissue promote the metastatic potential of cancer cells, suggesting the existence of a crosstalk between the adipose tissue and the surrounding tumour. Mitochondrial Ca
    MeSH term(s) Humans ; Adipose Tissue/pathology ; Adipocytes ; Obesity/complications ; Subcutaneous Fat/pathology ; Neoplasms/pathology
    Language English
    Publishing date 2024-04-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-55650-0
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  6. Article: The Mitochondrial Ca

    Gherardi, Gaia / Monticelli, Halenya / Rizzuto, Rosario / Mammucari, Cristina

    Frontiers in physiology

    2020  Volume 11, Page(s) 554904

    Abstract: Recently, the role of mitochondrial activity in high-energy demand organs and in the orchestration of whole-body metabolism has received renewed attention. In mitochondria, pyruvate oxidation, ensured by efficient mitochondrial pyruvate entry and matrix ... ...

    Abstract Recently, the role of mitochondrial activity in high-energy demand organs and in the orchestration of whole-body metabolism has received renewed attention. In mitochondria, pyruvate oxidation, ensured by efficient mitochondrial pyruvate entry and matrix dehydrogenases activity, generates acetyl CoA that enters the TCA cycle. TCA cycle activity, in turn, provides reducing equivalents and electrons that feed the electron transport chain eventually producing ATP. Mitochondrial Ca
    Language English
    Publishing date 2020-10-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2020.554904
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Skeletal muscle mitochondria in health and disease.

    De Mario, Agnese / Gherardi, Gaia / Rizzuto, Rosario / Mammucari, Cristina

    Cell calcium

    2021  Volume 94, Page(s) 102357

    Abstract: Mitochondrial activity warrants energy supply to oxidative myofibres to sustain endurance workload. The maintenance of mitochondrial homeostasis is ensured by the control of fission and fusion processes and by the mitophagic removal of aberrant ... ...

    Abstract Mitochondrial activity warrants energy supply to oxidative myofibres to sustain endurance workload. The maintenance of mitochondrial homeostasis is ensured by the control of fission and fusion processes and by the mitophagic removal of aberrant organelles. Many diseases are due to or characterized by dysfunctional mitochondria, and altered mitochondrial dynamics or turnover trigger myopathy per se. In this review, we will tackle the role of mitochondrial dynamics, turnover and metabolism in skeletal muscle, both in health and disease.
    Language English
    Publishing date 2021-01-30
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 757687-0
    ISSN 1532-1991 ; 0143-4160
    ISSN (online) 1532-1991
    ISSN 0143-4160
    DOI 10.1016/j.ceca.2021.102357
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1596: Show issues Location:
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  8. Article ; Online: The mitochondrial ATP-dependent potassium channel (mitoK

    Di Marco, Giulia / Gherardi, Gaia / De Mario, Agnese / Piazza, Ilaria / Baraldo, Martina / Mattarei, Andrea / Blaauw, Bert / Rizzuto, Rosario / De Stefani, Diego / Mammucari, Cristina

    Cell death & disease

    2024  Volume 15, Issue 1, Page(s) 58

    Abstract: ... ...

    Abstract MitoK
    MeSH term(s) Adenosine Triphosphate/metabolism ; Potassium Channels/metabolism ; Mitochondria/metabolism ; Muscle, Skeletal/metabolism ; Mitochondria, Heart/metabolism
    Chemical Substances mitochondrial K(ATP) channel ; Adenosine Triphosphate (8L70Q75FXE) ; Potassium Channels
    Language English
    Publishing date 2024-01-17
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2541626-1
    ISSN 2041-4889 ; 2041-4889
    ISSN (online) 2041-4889
    ISSN 2041-4889
    DOI 10.1038/s41419-024-06426-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: PSEN2 (presenilin 2) mutants linked to familial Alzheimer disease impair autophagy by altering Ca

    Fedeli, Chiara / Filadi, Riccardo / Rossi, Alice / Mammucari, Cristina / Pizzo, Paola

    Autophagy

    2019  Volume 15, Issue 12, Page(s) 2044–2062

    Abstract: PSEN2 (presenilin 2) is one of the 3 proteins that, when mutated, causes early onset familial Alzheimer disease (FAD) cases. In addition to its well-known role within the γ-secretase complex (the enzyme ultimately responsible for Aβ peptides formation), ... ...

    Abstract PSEN2 (presenilin 2) is one of the 3 proteins that, when mutated, causes early onset familial Alzheimer disease (FAD) cases. In addition to its well-known role within the γ-secretase complex (the enzyme ultimately responsible for Aβ peptides formation), PSEN2 is endowed with some γ-secretase-independent functions in distinct cell signaling pathways, such as the modulation of intracellular Ca
    MeSH term(s) Alzheimer Disease/genetics ; Alzheimer Disease/metabolism ; Animals ; Autophagosomes/metabolism ; Autophagy/genetics ; Autophagy/physiology ; Calcium/metabolism ; Cell Line, Tumor ; Endoplasmic Reticulum/metabolism ; Genetic Diseases, Inborn/metabolism ; Homeostasis ; Humans ; Lysosomes/genetics ; Lysosomes/metabolism ; Membrane Fusion/genetics ; Mice ; Mice, Knockout ; Mitochondria/metabolism ; Neurons/metabolism ; Presenilin-2/genetics ; Presenilin-2/metabolism ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/genetics ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism ; rab GTP-Binding Proteins/genetics ; rab GTP-Binding Proteins/metabolism ; rab7 GTP-Binding Proteins
    Chemical Substances PSEN2 protein, human ; Presenilin-2 ; rab7 GTP-Binding Proteins ; rab7 GTP-binding proteins, human ; rab7 GTP-binding proteins, mouse ; Sarcoplasmic Reticulum Calcium-Transporting ATPases (EC 3.6.3.8) ; rab GTP-Binding Proteins (EC 3.6.5.2) ; ATP2A1 protein, human (EC 7.2.2.10) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2019-03-27
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2454135-7
    ISSN 1554-8635 ; 1554-8627
    ISSN (online) 1554-8635
    ISSN 1554-8627
    DOI 10.1080/15548627.2019.1596489
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    Zs.A 6741: Show issues Location:
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  10. Article ; Online: Crosstalk between Mitochondrial Ca

    Gherardi, Gaia / Di Marco, Giulia / Rizzuto, Rosario / Mammucari, Cristina

    Oxidative medicine and cellular longevity

    2019  Volume 2019, Page(s) 1845321

    Abstract: Autophagy is responsible for the maintenance of skeletal muscle homeostasis, thanks to the removal of aberrant and dysfunctional macromolecules and organelles. During fasting, increased autophagy ensures the maintenance of the amino acid pool required ... ...

    Abstract Autophagy is responsible for the maintenance of skeletal muscle homeostasis, thanks to the removal of aberrant and dysfunctional macromolecules and organelles. During fasting, increased autophagy ensures the maintenance of the amino acid pool required for energy production. The activity of the mitochondrial Ca
    MeSH term(s) Autophagy ; Biological Transport ; Calcium/metabolism ; Humans ; Mitochondria/genetics ; Muscle, Skeletal/metabolism
    Chemical Substances Calcium (SY7Q814VUP)
    Language English
    Publishing date 2019-09-08
    Publishing country United States
    Document type Journal Article
    ISSN 1942-0994
    ISSN (online) 1942-0994
    DOI 10.1155/2019/1845321
    Database MEDical Literature Analysis and Retrieval System OnLINE

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