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  1. Article ; Online: Breeding colony contraction of Asian openbill stork (Anastomus oscitans): an eco-spatial monitoring from Keleghai River Bank, India.

    Mandal, Mrinmay

    Environmental monitoring and assessment

    2024  Volume 196, Issue 3, Page(s) 317

    Abstract: Asian openbill stork (Anastomus oscitans) colonies and also the numbers were enormous before some decades in some villages beside Keleghai River bank. However, there has been a significant decline in both the colonies and their populations. This present ... ...

    Abstract Asian openbill stork (Anastomus oscitans) colonies and also the numbers were enormous before some decades in some villages beside Keleghai River bank. However, there has been a significant decline in both the colonies and their populations. This present study investigates the rapid decline in the number of breeding colonies and birds, exploring the reasons behind this phenomenon. To address these inquiries, the study collects perceptions from various stakeholders through extensive field observations and interviews. Expeditions are conducted to comprehend the prevailing situation and associated circumstances. Qualitative observations reveal that human intervention, both direct and indirect, is limiting the development of stork colonies. Data analysis indicates that 37.5% of respondents attribute the contraction of bird colonies to changes in land use, while 26.3% point to the extermination of larger trees along the colony periphery. Additionally, 18.05% of opinions implicate the heavy use of pesticides and fertilizers in the wetland, 6.94% cite local climate change, and 11.11% cite other reasons. To validate the gathered information, the study employed temporal land use land cover (LULC) classification techniques. Random point pattern analysis from Google Image of 2023 is also utilized to reinforce the survey results. It enhances understanding of the spatio-temporal relationship. Subsequently, the study presents the correlation matrix to elucidate the relationship between stork colonies and contributing factors. It provides a clear insight into the underlying situations. Finally, a comparative analysis of the surveyed and spatial analysis information is conducted to detect and validate the perception of stakeholders. Based on these observations, the study formulates conservation measures for the bird habitat and their colonies in the study area.
    MeSH term(s) Animals ; Humans ; Rivers ; Environmental Monitoring ; Plant Breeding ; Birds ; India ; Conservation of Natural Resources
    Language English
    Publishing date 2024-02-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 782621-7
    ISSN 1573-2959 ; 0167-6369
    ISSN (online) 1573-2959
    ISSN 0167-6369
    DOI 10.1007/s10661-024-12485-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: Optimum Methods for Quasi-Orthographic Surface Imaging

    Mandal, Maniratnam

    2023  

    Abstract: The need for fast, effective and accurate surveys have become increasingly necessary. A major part of the research is supported by photographic surveys which are used for capturing expansive natural surfaces using a wide range of sensors -- visual, ... ...

    Abstract The need for fast, effective and accurate surveys have become increasingly necessary. A major part of the research is supported by photographic surveys which are used for capturing expansive natural surfaces using a wide range of sensors -- visual, infrared, ultrasonic, radio, etc. Because of the unpredictability and fast-varying characteristic of natural surfaces, it is often very difficult to capture and reconstruct them accurately. Moreover, the non-smooth nature results in the occlusion of major areas when a small number of captures are used for reconstruction, resulting in loss of important and maybe significant information or surface features. In a perfect orthographic reconstruction, images must be captured normal to each point on the surface which is practically implausible. This thesis aims at proposing several algorithms for deciding optimal capture points, given a surface, such that the optimal captures can be used for an approximate orthographic reconstruction. An approximate orthographic capture has been attributed to a small field of view and a closed form relationship has been derived for evaluating local orthographic capture region which varies depending on the point of capture on the surface. Based on the formula to calculate approximate local orthographic regions, several algorithms have been developed using non-convex optimization techniques for covering the entire surface with minimum number of such capture points. The algorithms have been compared on the basis of accuracy and computational complexity and parameters have been tuned depending on the nature of the surface. A separate algorithm has been proposed to identify such capture points empirically depending on the local surface-curvatures. Given these algorithms, users can make informed choices regarding which to adopt in their application as per their requirements.

    Comment: arXiv admin note: text overlap with arXiv:2305.08113
    Keywords Electrical Engineering and Systems Science - Image and Video Processing
    Subject code 621
    Publishing date 2023-05-14
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Integrated CO

    Mandal, Mrinmay

    Dalton transactions (Cambridge, England : 2003)

    2020  Volume 49, Issue 47, Page(s) 17140–17142

    Abstract: The capture, storage, and utilization (CSU) of ... ...

    Abstract The capture, storage, and utilization (CSU) of CO
    Language English
    Publishing date 2020-11-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472887-4
    ISSN 1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
    ISSN (online) 1477-9234 ; 1364-5447
    ISSN 0300-9246 ; 1477-9226
    DOI 10.1039/d0dt03667f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Local Understanding and Meaning of Dual Protection Within Adolescent Sexual and Reproductive Health.

    Mandal, Mahua

    The Journal of adolescent health : official publication of the Society for Adolescent Medicine

    2020  Volume 67, Issue 6, Page(s) 737–738

    MeSH term(s) Adolescent ; Attitude ; Consensus ; Female ; Humans ; Reproductive Health ; Sexual Behavior ; Sexual Health
    Language English
    Publishing date 2020-11-18
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1063374-1
    ISSN 1879-1972 ; 1054-139X
    ISSN (online) 1879-1972
    ISSN 1054-139X
    DOI 10.1016/j.jadohealth.2020.09.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Attenuation of biofilm and quorum sensing regulated virulence factors of an opportunistic pathogen Pseudomonas aeruginosa by phytofabricated silver nanoparticles.

    Rather, Muzamil Ahmad / Mandal, Manabendra

    Microbial pathogenesis

    2023  Volume 185, Page(s) 106433

    Abstract: Green-synthesized nanoparticles provide an effective strategy for inhibiting microbial pathogenesis by affecting biofilm formation, quorum sensing (QS), and other surface properties of microorganisms. QS is a density-dependent communication signaling ... ...

    Abstract Green-synthesized nanoparticles provide an effective strategy for inhibiting microbial pathogenesis by affecting biofilm formation, quorum sensing (QS), and other surface properties of microorganisms. QS is a density-dependent communication signaling cascade that regulates biofilm formation and other pathogenic factors of Pseudomonas aeruginosa. In this context, the effect of phytofabricated silver nanoparticles (CC-AgNPs) synthesized using Cuphea carthagenensis extract on biofilm, QS, and QS-dependent virulence factors of P. aeruginosa were evaluated in this study. CC-AgNPs demonstrated significant attenuation of biofilm, QS, and QS-dependent virulence factors at sub-MICs. A significant inhibition of 88.39 ± 4.32 %, 79.64 ± 3.31 %, 73.07 ± 3.0 %, and 61.67 ± 1.5 % of biofilm formation, quorum sensing, pyocyanin, and LasB elastase, respectively was reported in the study at 20 μg/mL. The study also demonstrated a significant reduction of LasA Staphylolytic activity and 91.37 ± 1.05 % exoprotease production in comparison to untreated control. The lower concentrations of CC-AgNPs also demonstrated significant attenuation of biofilm and other virulence factors suggesting the strong potency of NPs against P. aeruginosa. XTT analysis reported the effect of CC-AgNPs on sessile cells of P. aeruginosa without impacting growth of planktonic cells at sub-MICs. Cell-proliferation study in human cell lines (HEK 293 and Caco-2 cells) demonstrated the safe nature of CC-AgNPs at tested concentrations. This study is novel in a way that environmentally friendly CC-AgNPs were used to inhibit QS at sub-MICs without killing the tested strains, therefore, could be developed as an anti-virulent drug to overcome biofilm and antimicrobial resistance problems.
    MeSH term(s) Humans ; Quorum Sensing ; Virulence Factors/metabolism ; Pseudomonas aeruginosa ; Silver/pharmacology ; Metal Nanoparticles ; Caco-2 Cells ; HEK293 Cells ; Anti-Bacterial Agents/pharmacology ; Biofilms
    Chemical Substances Virulence Factors ; Silver (3M4G523W1G) ; Anti-Bacterial Agents
    Language English
    Publishing date 2023-10-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 632772-2
    ISSN 1096-1208 ; 0882-4010
    ISSN (online) 1096-1208
    ISSN 0882-4010
    DOI 10.1016/j.micpath.2023.106433
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Spatiotemporal genome diversity of SARS-CoV-2 in wastewater: a two-year global epidemiological study.

    Mandal, Manisha / Mandal, Shyamapada

    Environmental monitoring and assessment

    2023  Volume 196, Issue 1, Page(s) 44

    Abstract: Wastewater surveillance locally and globally is important for the investigation of the molecular epidemiological features of SARS-CoV-2 in the environment. The current study investigated the genomic diversity and mutation profile of SARS-CoV-2 variants ... ...

    Abstract Wastewater surveillance locally and globally is important for the investigation of the molecular epidemiological features of SARS-CoV-2 in the environment. The current study investigated the genomic diversity and mutation profile of SARS-CoV-2 variants in wastewater for the period spanning COVID-19 pandemic up to December, 2022. A total of 3618 complete SARS-CoV-2 genome sequences from waste water samples submitted to the GISAID database were retrieved. The SARS-CoV-2 sequences were subjected to pairwise alignment against reference, followed by clade and lineage assignment (based on Nextstrain, GISAID and Pango), distance metric phylogenetic analysis, and detection of substitution mutations. Following GISAID, Nextstrain, and Pango nomenclatures, an overall agreement in clade and lineage determination in wastewater samples was observed. There was successive appearance, dissemination, and disappearance of SARS-CoV-2 lineages along time in wastewater. The SARS-CoV-2 genomes from wastewater were clustered into the variants of concern (VOC) as Alpha GRY (B.1.1.7 + Q.7), Delta GK (B.1.617.2 + AY.*), and Omicron GRA (BA.1*, BA.2* + B.1.1.529, BA.5*). The evolutionary rate was 9.63e-04 substitutions/site/year for SARS-CoV-2 in wastewater. B.1.1.7 was less prevalent than B.1.617.2 in 2021, appeared in succession, and BA.1, BA.2, BA.5 were serially detected in 2022, the latter strain continued to persist in wastewater. The N501Y, E484K/Q, K417N/T, L452R, T478K spike substitutions remained dominant attribute of SARS-CoV-2 VOCs. The study underlines the importance of wastewater surveillance for enumerating spatiotemporal diversity of SARS-CoV-2 variants and mutations, which might pave the way for novel antiviral and vaccine designing towards management and prevention of SARS-CoV-2 infection.
    MeSH term(s) Humans ; SARS-CoV-2/genetics ; Wastewater ; COVID-19/epidemiology ; Pandemics ; Phylogeny ; Wastewater-Based Epidemiological Monitoring ; Environmental Monitoring ; Epidemiologic Studies ; Mutation
    Chemical Substances Wastewater
    Language English
    Publishing date 2023-12-16
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 782621-7
    ISSN 1573-2959 ; 0167-6369
    ISSN (online) 1573-2959
    ISSN 0167-6369
    DOI 10.1007/s10661-023-12228-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Computerized cognitive testing in patients with Parkinson's disease: an Indian perspective.

    Mandal, Moulika / Srivastava, Kashish

    Neurodegenerative disease management

    2023  Volume 13, Issue 4, Page(s) 235–243

    Abstract: Aim: ...

    Abstract Aim:
    MeSH term(s) Humans ; Aged ; Parkinson Disease/complications ; Parkinson Disease/diagnosis ; Parkinson Disease/psychology ; Neuropsychological Tests ; Cognitive Dysfunction/diagnosis ; Cognitive Dysfunction/etiology
    Language English
    Publishing date 2023-06-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2608846-0
    ISSN 1758-2032 ; 1758-2024
    ISSN (online) 1758-2032
    ISSN 1758-2024
    DOI 10.2217/nmt-2023-0002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Nanoparticle-mediated gene therapy as a novel strategy for the treatment of retinoblastoma.

    Mandal, Madhurima / Banerjee, Indranil / Mandal, Mahitosh

    Colloids and surfaces. B, Biointerfaces

    2022  Volume 220, Page(s) 112899

    Abstract: Over the last two decades, nanoparticulate delivery systems have revolutionized cancer treatment by achieving target-specific delivery, enhanced bioavailability, and improved toxicity profile. The increasing interest in nanotechnology for cancer ... ...

    Abstract Over the last two decades, nanoparticulate delivery systems have revolutionized cancer treatment by achieving target-specific delivery, enhanced bioavailability, and improved toxicity profile. The increasing interest in nanotechnology for cancer treatment stems from the unique physicochemical properties of nanoparticles (for instance, small size, surface characteristics, etc.). Indeed, different anticancer drugs can be effectively delivered through nano-delivery systems nowadays. However, the application of such delivery systems in the arena of gene therapy remains in its infancy. Moreover, the treatment of retinoblastoma (RB), an aggressive ocular cancer of childhood, is a major problem in developing countries owing to the late diagnosis of this type of cancer. While adeno-associated virus-based delivery strategies remain the mainstay of the gene delivery method due to their high efficiency, other delivery systems, such as non-viral nanoparticles (NPs) are being developed as alternative therapeutic modalities. Indeed, different nanoparticle formulations such as lipid-based nanoparticles, polymeric nanoparticles, gold nanoparticles have displayed improved gene delivery efficiency in retinal diseases. This review article focuses on the nanoparticle mediated gene therapy approaches in the treatment of RB and highlights the attempts made to develop improved formulations for the treatment of RB. We delineate the current status of NPs as a gene delivery vehicle and cover the future perspective of this exciting field of research. Also, we discuss the achievement, challenges, and opportunities of nanomedicine to treat RB and mention novel engineering approaches that leverage our growing understanding of tumor biology and mechanisms of NPs uptake to develop more effective nanotherapeutics for RB patients.
    MeSH term(s) Humans ; Drug Delivery Systems ; Retinoblastoma/genetics ; Retinoblastoma/therapy ; Gold/chemistry ; Metal Nanoparticles/chemistry ; Nanoparticles/chemistry ; Genetic Therapy ; Retinal Neoplasms/genetics ; Retinal Neoplasms/therapy
    Chemical Substances Gold (7440-57-5)
    Language English
    Publishing date 2022-10-04
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1500523-9
    ISSN 1873-4367 ; 0927-7765
    ISSN (online) 1873-4367
    ISSN 0927-7765
    DOI 10.1016/j.colsurfb.2022.112899
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: High-flow nasal oxygen in severe COVID-19 pneumonia and tocilizumab.

    Mandal, M / Mazza, M / Esquinas, A M

    Infectious diseases now

    2022  Volume 52, Issue 5, Page(s) 324–325

    MeSH term(s) Antibodies, Monoclonal, Humanized/therapeutic use ; COVID-19/drug therapy ; Humans ; Oxygen/therapeutic use
    Chemical Substances Antibodies, Monoclonal, Humanized ; tocilizumab (I031V2H011) ; Oxygen (S88TT14065)
    Language English
    Publishing date 2022-05-07
    Publishing country France
    Document type Letter ; Comment
    ISSN 2666-9919
    ISSN (online) 2666-9919
    DOI 10.1016/j.idnow.2022.04.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Studying the Effect of MBNL1 and MBNL2 Loss in Skeletal Muscle Regeneration.

    Yadava, Ramesh S / Mandal, Mahua / Mahadevan, Mani S

    International journal of molecular sciences

    2024  Volume 25, Issue 5

    Abstract: Loss of function of members of the muscleblind-like (MBNL) family of RNA binding proteins has been shown to play a key role in the spliceopathy of RNA toxicity in myotonic dystrophy type 1 (DM1), the most common muscular dystrophy affecting adults and ... ...

    Abstract Loss of function of members of the muscleblind-like (MBNL) family of RNA binding proteins has been shown to play a key role in the spliceopathy of RNA toxicity in myotonic dystrophy type 1 (DM1), the most common muscular dystrophy affecting adults and children. MBNL1 and MBNL2 are the most abundantly expressed members in skeletal muscle. A key aspect of DM1 is poor muscle regeneration and repair, leading to dystrophy. We used a BaCl
    MeSH term(s) Humans ; Child ; Mice ; Animals ; Alternative Splicing ; Myotonic Dystrophy/genetics ; Muscle, Skeletal/metabolism ; Mice, Knockout ; Disease Models, Animal ; RNA/metabolism ; RNA-Binding Proteins/metabolism
    Chemical Substances RNA (63231-63-0) ; MBNL1 protein, human ; RNA-Binding Proteins ; MBNL2 protein, human
    Language English
    Publishing date 2024-02-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25052687
    Database MEDical Literature Analysis and Retrieval System OnLINE

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