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  1. Article: Carbonized Tetracycline: a new class of nanomaterial with tuneable antioxidant, reduced cytotoxicity, immunomodulatory, and osteogenic properties.

    Mandal, Saptarshi / Annamalai, Ramkumar T

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Tetracycline (TET), a broad-spectrum antibiotic, also possesses different non-antibiotic activities such as inhibition of metalloproteinase (MMP), anti-inflammatory, antioxidant, high bone affinity, etc. However, the comparatively low efficacy of these ... ...

    Abstract Tetracycline (TET), a broad-spectrum antibiotic, also possesses different non-antibiotic activities such as inhibition of metalloproteinase (MMP), anti-inflammatory, antioxidant, high bone affinity, etc. However, the comparatively low efficacy of these non-antibiotic properties along with adverse effects such as hyperpigmentation, phototoxicity, long-term skeletal retention, etc. have not helped their broad utilization similar to their use as an antibiotic. In a unique attempt to improve the non-antibiotic properties while reducing the adverse effects, we converted the TET to nano-carbons through partial carbonization. After sorting out two water-dispersible C-TETs (C-TET
    Language English
    Publishing date 2023-11-01
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.10.30.564661
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Interacting fermions in two dimension in simultaneous presence of disorder and magnetic field.

    Mandal, Saptarshi / Gupta, Sanjay

    Journal of physics. Condensed matter : an Institute of Physics journal

    2022  Volume 34, Issue 21

    Abstract: We study the revival of Hofstadter butterfly due to the competition between disorder and electronic interaction using mean field approximation of unrestricted Hartree Fock method at zero temperature for two dimensional square and honeycomb lattices. ... ...

    Abstract We study the revival of Hofstadter butterfly due to the competition between disorder and electronic interaction using mean field approximation of unrestricted Hartree Fock method at zero temperature for two dimensional square and honeycomb lattices. Interplay of disorder and electronic correlation to nullify each other is corroborated by the fact that honeycomb lattice needs more strength of electronic correlation owing to its less co-ordination number which enhances the effect of disorder. The extent of revival of the butterfly is better in square lattice than honeycomb lattice due to higher coordination number. The effect of disorder and interaction is also investigated to study entanglement entropy and entanglement spectrum. We find that for honeycomb lattice area law of entanglement entropy is obeyed in all cases but for square lattice there is some departure from area law for larger subsystems. The entanglement spectrum have the reflection symmetry of the original butterfly of the Hofstadter spectrum. The interaction induces a gap in the entanglement spectrum as well conforming the correspondence between physical spectrum and entanglement spectrum. The effect of disorder closes the interaction induced gap in the entanglement spectrum establishing the nullification of interaction due to disorder and vice versa.
    Language English
    Publishing date 2022-03-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472968-4
    ISSN 1361-648X ; 0953-8984
    ISSN (online) 1361-648X
    ISSN 0953-8984
    DOI 10.1088/1361-648X/ac5d8a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Demystifying non-invasive approaches for screening jaundice in low resource settings: a review.

    Abiha, Umme / Banerjee, Dip Sankar / Mandal, Saptarshi

    Frontiers in pediatrics

    2023  Volume 11, Page(s) 1292678

    Abstract: All national and international pediatric guidelines universally prescribe meticulous bilirubin screening for neonates as a critical measure to mitigate the incidence of acute bilirubin encephalopathy (ABE) and Kernicterus. The prevailing gold standard ... ...

    Abstract All national and international pediatric guidelines universally prescribe meticulous bilirubin screening for neonates as a critical measure to mitigate the incidence of acute bilirubin encephalopathy (ABE) and Kernicterus. The prevailing gold standard for jaundice detection in neonates necessitates invasive blood collection, followed by subsequent biochemical testing. While the invasive procedure provides dependable bilirubin measurements and continues to be the sole gold standard diagnostic method for assessing bilirubin concentration. There exists a pressing need to innovate non-invasive screening tools that alleviate the sampling stress endured by newborns, mitigate iatrogenic anemia, and expedite the turnaround time for obtaining results. The exploration of non-invasive modalities for bilirubin measurements is gaining momentum, driven by the overarching goal of minimizing the number of pricks inflicted upon neonates, thereby rendering screening a swift, efficient, comfortable, and dependable process. This comprehensive review article delves extensively into the array of non-invasive approaches and digital solutions that have been proposed, implemented, and utilized for neonatal bilirubin screening, with a particular emphasis on their application in low-resource settings. Within this context, the review sheds light on the existing methodologies and their practical applications, with a specific focus on transcutaneous bilirubin meters. Moreover, it underscores the prevailing open challenges in this domain and outlines potential directions for future research endeavors. Notably, the review underscores the imperative need for robust educational programs targeted at both families and healthcare personnel to expedite the process of seeking timely care for neonatal jaundice. Additionally, it underscores the necessity for the development of enhanced screening and diagnostic tools that can offer greater accuracy in clinical practice.
    Language English
    Publishing date 2023-11-20
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2023.1292678
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Visible light-induced charge injection and migration in self-assembled carbon dot-DNA-carbon dot nano-dumbbell obtained through controlled stoichiometric conjugation.

    Mandal, Saptarshi / Das, Prolay

    Nanoscale

    2021  Volume 13, Issue 33, Page(s) 14147–14155

    Abstract: The potential of carbon dots (CDs) for photonic conversion to charged states, together with the ability of DNA to transport such charge for extensive charge separation, offers an opportunity to control directionality of migration for photo-induced ... ...

    Abstract The potential of carbon dots (CDs) for photonic conversion to charged states, together with the ability of DNA to transport such charge for extensive charge separation, offers an opportunity to control directionality of migration for photo-induced radical cations in CD-DNA based nano-assemblies. This is achieved through engineering the reaction valency of CDs whereby one CD is covalently conjugated with one ssDNA strand. Subsequently, a CD-DNA-CD nano-dumbbell architecture was created through hybridization mediated self-assembly. The time and intensity-dependent transduction of visible light photonic energy to chemical potential in DNA was achieved through irradiation of 1,4-diaminoathraquinone and glyoxal derived CD with 100 W tungsten source and natural sunlight. Following charge injection by CD, the radical cation migration in DNA was perceived through trapping of the hole in repeated GG steps in the DNA. Overall, a breakthrough in visible-light-induced charge transfer by CD into DNA was achieved, potentially applicable to optobioelectronics.
    MeSH term(s) Carbon ; DNA ; Light ; Nucleic Acid Hybridization ; Quantum Dots
    Chemical Substances Carbon (7440-44-0) ; DNA (9007-49-2)
    Language English
    Publishing date 2021-08-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2515664-0
    ISSN 2040-3372 ; 2040-3364
    ISSN (online) 2040-3372
    ISSN 2040-3364
    DOI 10.1039/d1nr01689j
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Pediatric Therapeutic Plasma Exchange: Coming of Age?

    Mandal, Saptarshi / Sinha, Aditi

    Indian journal of pediatrics

    2021  Volume 88, Issue 8, Page(s) 745–746

    MeSH term(s) Child ; Humans ; Multiple Organ Failure ; Plasma Exchange ; Plasmapheresis
    Language English
    Publishing date 2021-05-26
    Publishing country India
    Document type Editorial ; Comment
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-021-03821-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Elucidating the relationship between red fluorescence and structural dynamics of carbon dots dispersed in different solvents.

    Mandal, Saptarshi / Erimban, Shakkira / Banerjee, Subhrajeet / Daschakraborty, Snehasis / Das, Prolay

    Physical chemistry chemical physics : PCCP

    2023  Volume 25, Issue 35, Page(s) 23645–23657

    Abstract: The mechanism of intrinsic fluorescence of carbon dots (CDs), the latest nanomaterial from the carbon family, was supposedly deciphered through multiple theories. However, the much sought-after persistent red emission of CDs as a foreseeable consequence ... ...

    Abstract The mechanism of intrinsic fluorescence of carbon dots (CDs), the latest nanomaterial from the carbon family, was supposedly deciphered through multiple theories. However, the much sought-after persistent red emission of CDs as a foreseeable consequence of experiments remains elusive prompting the question of whether tuning of the red emission of CDs is a predictable outcome or a serendipitous coincidence. Herein, we tried to decode the same by exploring Alizarin Red S (ARS)-based red emitting CDs in different solvents with wisely chosen analytical tools. The findings are aptly supported by molecular dynamics studies through an experimental intuition-driven model-building approach. Parallel interception of the CDs with powder X-ray diffraction (pXRD) and photophysical spectroscopic studies revealed an important relationship between the solvent and CDs. Tautomerism, a well-known phenomenon with chemical entities, was found to be operative for CDs that greatly influence the Stokes shift and ultimately the fluorescence outcome. Most importantly, pXRD studies established the turbostratism of the CDs where the well-ordered graphitic structure of CDs gets disrupted with solvent molecules. The extent of such disruption is a function of solvent and CD composition that plays a formidable role in obtaining red fluorescence. Thus, for the first time, we demonstrate that the red emission of CDs is related to its structural integrity and if taken care of could be sustained, a tremendously desirable outcome for relevant applications.
    Language English
    Publishing date 2023-09-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp02498a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Dipole-dipole interaction induced phases in hydrogen-bonded squaric acid crystal.

    Vijigiri, Vikas / Mandal, Saptarshi

    Journal of physics. Condensed matter : an Institute of Physics journal

    2020  Volume 32, Issue 28, Page(s) 285802

    Abstract: We study the finite-temperature phase diagram of proton ordering of a quasi-two dimensional hydrogen-bonded system, namely the squaric acid crystal ( ... ...

    Abstract We study the finite-temperature phase diagram of proton ordering of a quasi-two dimensional hydrogen-bonded system, namely the squaric acid crystal (H
    Language English
    Publishing date 2020-02-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472968-4
    ISSN 1361-648X ; 0953-8984
    ISSN (online) 1361-648X
    ISSN 0953-8984
    DOI 10.1088/1361-648X/ab7ba1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Ultrasensitive visual detection of mycotoxin citrinin with yellow-light emitting carbon dot and Congo red

    Mandal, Saptarshi / Das, Prolay

    Food chemistry. 2020 May 15, v. 312

    2020  

    Abstract: Ultrasensitive visual detection of mycotoxin citrinin is reported here using a novel yellow-light emitting Carbon dot (CD) and Congo red dye. Detection strategy is based on higher binding affinity of citrinin with diammonium citrate, and urea derived CD ... ...

    Abstract Ultrasensitive visual detection of mycotoxin citrinin is reported here using a novel yellow-light emitting Carbon dot (CD) and Congo red dye. Detection strategy is based on higher binding affinity of citrinin with diammonium citrate, and urea derived CD over Congo red in presence of Mg2+. Congo red statically quenched the yellow fluorescence of CD, resulting in emission in red region, which was restored in presence of citrinin. Visual limit of detection (LOD) of 10 pmol and spectroscopic LOD of 6.6 pmol/mL was achieved within 5 min of incubation with citrinin. The assembly was found to respond well for citrinin detection in the presence of Aflatoxin b1 (AFL b1) and Ochratoxin A (OTA), that frequently co-exist with citrinin in real food samples. The method exhibits immense potential to sense citrinin in sub-nanogram range by visual inspection in an inexpensive yet robust on-site detection platform in relevant food packaging and agricultural industry.
    Keywords Congo red ; aflatoxin B1 ; agricultural industry ; binding capacity ; carbon ; citrates ; citrinin ; detection limit ; fluorescence ; food packaging ; magnesium ; ochratoxin A ; spectroscopy ; urea
    Language English
    Dates of publication 2020-0515
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2019.126076
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Ultrasensitive visual detection of mycotoxin citrinin with yellow-light emitting carbon dot and Congo red.

    Mandal, Saptarshi / Das, Prolay

    Food chemistry

    2019  Volume 312, Page(s) 126076

    Abstract: Ultrasensitive visual detection of mycotoxin citrinin is reported here using a novel yellow-light emitting Carbon dot (CD) and Congo red dye. Detection strategy is based on higher binding affinity of citrinin with diammonium citrate, and urea derived CD ... ...

    Abstract Ultrasensitive visual detection of mycotoxin citrinin is reported here using a novel yellow-light emitting Carbon dot (CD) and Congo red dye. Detection strategy is based on higher binding affinity of citrinin with diammonium citrate, and urea derived CD over Congo red in presence of Mg
    MeSH term(s) Aflatoxin B1/chemistry ; Carbon ; Citrinin/analysis ; Congo Red ; Limit of Detection ; Ochratoxins/chemistry
    Chemical Substances Ochratoxins ; ochratoxin A (1779SX6LUY) ; Citrinin (3S697X6SNZ) ; Congo Red (3U05FHG59S) ; Carbon (7440-44-0) ; Aflatoxin B1 (9N2N2Y55MH)
    Language English
    Publishing date 2019-12-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2019.126076
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Effect of platelet-rich plasma on healing of autologous graft after anterior cruciate ligament reconstruction: a randomized control trial.

    Munde, Kishor / Banerjee, Sumit / Gahlot, Nitesh / Elhence, Abhay / Mandal, Saptarshi / Yadav, Taruna

    Regenerative medicine

    2023  Volume 18, Issue 8, Page(s) 601–610

    Abstract: Aim: ...

    Abstract Aim:
    MeSH term(s) Humans ; Anterior Cruciate Ligament Injuries/surgery ; Knee Joint ; Anterior Cruciate Ligament/surgery ; Anterior Cruciate Ligament Reconstruction/methods ; Platelet-Rich Plasma ; Treatment Outcome
    Language English
    Publishing date 2023-07-25
    Publishing country England
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2274500-2
    ISSN 1746-076X ; 1746-0751
    ISSN (online) 1746-076X
    ISSN 1746-0751
    DOI 10.2217/rme-2023-0108
    Database MEDical Literature Analysis and Retrieval System OnLINE

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