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  1. AU="Mang, N"
  2. AU=Marwick Thomas H
  3. AU="Pedaletti, G."
  4. AU="Oliveira, Cleide Dantas"
  5. AU="Zelcer, Noam"
  6. AU="Appleton, Noa"
  7. AU="Rashid, Rijwana"
  8. AU="Luther-Tontasse, Emma"
  9. AU="Zohoori, Namvar"
  10. AU=Rosensweig Clark
  11. AU="Leff, Jonathan D"
  12. AU="Akira Goto"
  13. AU="Javier Pizarro-Cerda"
  14. AU="Oakley, James V"
  15. AU="Wen, Teresa H"
  16. AU="Li, Huiyu"
  17. AU="Pannala, Ananth S"
  18. AU="Noda, K."
  19. AU="Almeida, Carolina Aparecida Faria"
  20. AU=Khoshakhlagh Arezou
  21. AU="Sofija Glamočlija"
  22. AU="Fleming, Sherry D"
  23. AU="Minkina, Tatiana M"
  24. AU="Fonseca, Danielle"
  25. AU="Maximilian, Carmen-Rodica"
  26. AU="Heuer, Lauren B"
  27. AU="Pan, Judy"
  28. AU="Doro, M."
  29. AU="Navarro-Zapata, Alfonso"
  30. AU="Martin, Emanuel H"
  31. AU="Biswas, Arnab"
  32. AU="Kurt Pfister"
  33. AU="Stefano Brignola"
  34. AU="Nierzwicki, Łukasz"
  35. AU="Benvin, Iva"
  36. AU="Sardesai, S. C."
  37. AU="Aldrees, Rana"

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  1. Artikel: Correlation between Neutrophil-to-Lymphocyte Ratio and Cerebral Edema in Children with Severe Diabetic Ketoacidosis.

    Scutca, Alexandra-Cristina / Nicoară, Delia-Maria / Mang, Niculina / Jugănaru, Iulius / Brad, Giorgiana-Flavia / Mărginean, Otilia

    Biomedicines

    2023  Band 11, Heft 11

    Abstract: Diabetic ketoacidosis (DKA), a common onset modality of type 1 diabetes mellitus (T1DM), can lead, in rare instances, to the development of cerebral edema, which is the leading cause of mortality in T1DM. Aside from the identification of several ... ...

    Abstract Diabetic ketoacidosis (DKA), a common onset modality of type 1 diabetes mellitus (T1DM), can lead, in rare instances, to the development of cerebral edema, which is the leading cause of mortality in T1DM. Aside from the identification of several demographic and clinical risk factors for cerebral edema, attention has also been drawn to the possible link between systemic inflammation and neuroinflammation. This single-center retrospective study of 98 children with severe DKA aimed to investigate the possible relationship between neutrophil-to-lymphocyte ratio NLR) levels and the presence of cerebral edema. Patients were classified into three groups: alert (
    Sprache Englisch
    Erscheinungsdatum 2023-11-05
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11112976
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  2. Buch: Mathematik im Alltag

    Mang, Nathalie

    differenzierte Arbeitsblätter für den Mathematikunterricht ; 7./8. Klasse [Gymnasium]

    (Bergedorfer Unterrichtsideen ; Mathematik)

    2015  

    Verfasserangabe Nathalie Mang
    Serientitel Bergedorfer Unterrichtsideen
    Mathematik
    Schlagwörter Mathematikunterricht
    Sprache Deutsch
    Umfang 98 S., Ill., graph. Darst.
    Ausgabenhinweis 1. Aufl.
    Verlag Persen Verl., AAP Lehrerfachverl
    Erscheinungsort Hamburg
    Dokumenttyp Buch
    ISBN 3403234541 ; 9783403234548
    Datenquelle Ehemaliges Sondersammelgebiet Küsten- und Hochseefischerei

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  3. Artikel ; Online: Assessing the Relationship between Systemic Immune-Inflammation Index and Metabolic Syndrome in Children with Obesity.

    Nicoară, Delia-Maria / Munteanu, Andrei-Ioan / Scutca, Alexandra-Cristina / Mang, Niculina / Juganaru, Iulius / Brad, Giorgiana-Flavia / Mărginean, Otilia

    International journal of molecular sciences

    2023  Band 24, Heft 9

    Abstract: Childhood obesity represents a worldwide concern as many countries have reported an increase in its incidence, with possible cardiovascular long-term implications. The mechanism that links cardiovascular disease to obesity is related to low-grade ... ...

    Abstract Childhood obesity represents a worldwide concern as many countries have reported an increase in its incidence, with possible cardiovascular long-term implications. The mechanism that links cardiovascular disease to obesity is related to low-grade inflammation. We designed this study to investigate the diagnostic utility of inflammatory indices (NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; SII, systemic immune-inflammation index; SIRI, systemic inflammation response index) in obese children with metabolic syndrome (MetS) and their relationship with cardiometabolic risk biomarkers, such as the Homeostasis Model Assessment of Insulin Resistance (HOMA-IR), triglyceride-to-high-density lipoprotein cholesterol (TG:HDL-C), and non-high-density lipoprotein cholesterol (non-HDL-C). A total of 191 obese children from one large Romanian reference center was included in the study. Patients were classified in two groups according to the presence (MetS group) or absence (non-MetS group) of metabolic syndrome. According to our results, the SII index proved to have diagnostic value in distinguishing MetS patients among children with obesity (AUC = 0.843, a sensitivity of 0.83, and a specificity of 0.63). Furthermore, the SII was positively associated with cardiometabolic risk biomarkers (HOMA-IR,
    Mesh-Begriff(e) Humans ; Child ; Metabolic Syndrome/epidemiology ; Pediatric Obesity/complications ; Insulin Resistance/physiology ; Inflammation/complications ; Cholesterol ; Cardiovascular Diseases/etiology ; Triglycerides ; Cholesterol, HDL ; Biomarkers
    Chemische Substanzen Cholesterol (97C5T2UQ7J) ; Triglycerides ; Cholesterol, HDL ; Biomarkers
    Sprache Englisch
    Erscheinungsdatum 2023-05-08
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24098414
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  4. Artikel: Central precocious puberty in Prader-Willi syndrome: a narrative review.

    Nicoară, Delia-Maria / Scutca, Alexandra-Cristina / Mang, Niculina / Juganaru, Iulius / Munteanu, Andrei-Ioan / Vitan, Luiza / Mărginean, Otilia

    Frontiers in endocrinology

    2023  Band 14, Seite(n) 1150323

    Abstract: Prader-Willi syndrome (PWS, OMIM176270) is a rare genetic disorder with recognizable dysmorphic features and multisystemic consequences such as endocrine, neurocognitive and metabolic ones. Although most patients with Prader-Willi syndrome exhibit ... ...

    Abstract Prader-Willi syndrome (PWS, OMIM176270) is a rare genetic disorder with recognizable dysmorphic features and multisystemic consequences such as endocrine, neurocognitive and metabolic ones. Although most patients with Prader-Willi syndrome exhibit hypogonadotropic hypogonadism, there is variability regarding sexual maturation, with precocious puberty occurring in rare cases. Our aim is to elaborate a thorough review of Prader-Willi patients with central precocious puberty, in order to raise awareness of such cases and to enhance our knowledge regarding the diagnosis and prompt treatment of this particular PWS patients.
    Mesh-Begriff(e) Humans ; Prader-Willi Syndrome/complications ; Prader-Willi Syndrome/diagnosis ; Puberty, Precocious/diagnosis ; Puberty, Precocious/etiology ; Sexual Maturation ; Hypogonadism/complications ; Hypogonadism/diagnosis ; Knowledge
    Sprache Englisch
    Erscheinungsdatum 2023-05-08
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1150323
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  5. Artikel ; Online: Objective hand eczema severity assessment with automated lesion anatomical stratification.

    Amruthalingam, Ludovic / Mang, Nora / Gottfrois, Philippe / Gonzalez Jimenez, Alvaro / Maul, Julia-Tatjana / Kunz, Michael / Pouly, Marc / Navarini, Alexander A

    Experimental dermatology

    2023  Band 32, Heft 4, Seite(n) 521–528

    Abstract: Hand eczema (HE) is one of the most frequent dermatoses, known to be both relapsing and remitting. Regular and precise evaluation of the disease severity is key for treatment management. Current scoring systems such as the hand eczema severity index ( ... ...

    Abstract Hand eczema (HE) is one of the most frequent dermatoses, known to be both relapsing and remitting. Regular and precise evaluation of the disease severity is key for treatment management. Current scoring systems such as the hand eczema severity index (HECSI) suffer from intra- and inter-observer variance. We propose an automated system based on deep learning models (DLM) to quantify HE lesions' surface and determine their anatomical stratification. In this retrospective study, a team of 11 experienced dermatologists annotated eczema lesions in 312 HE pictures, and a medical student created anatomical maps of 215 hands pictures based on 37 anatomical subregions. Each data set was split into training and test pictures and used to train and evaluate two DLMs, one for anatomical mapping, the other for HE lesions segmentation. On the respective test sets, the anatomy DLM achieved average precision and sensitivity of 83% (95% confidence interval [CI] 80-85) and 85% (CI 82-88), while the HE DLM achieved precision and sensitivity of 75% (CI 64-82) and 69% (CI 55-81). The intraclass correlation of the predicted HE surface with dermatologists' estimated surface was 0.94 (CI 0.90-0.96). The proposed method automatically predicts the anatomical stratification of HE lesions' surface and can serve as support to evaluate hand eczema severity, improving reliability, precision and efficiency over manual assessment. Furthermore, the anatomical DLM is not limited to HE and can be applied to any other skin disease occurring on the hands such as lentigo or psoriasis.
    Mesh-Begriff(e) Humans ; Retrospective Studies ; Reproducibility of Results ; Severity of Illness Index ; Hand Dermatoses/diagnosis ; Eczema/pathology
    Sprache Englisch
    Erscheinungsdatum 2023-01-24
    Erscheinungsland Denmark
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1130936-2
    ISSN 1600-0625 ; 0906-6705
    ISSN (online) 1600-0625
    ISSN 0906-6705
    DOI 10.1111/exd.14744
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    Zs.A 3508: Hefte anzeigen Standort:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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  6. Artikel ; Online: Changes in the peripheral blood cell count in pediatric patients with Down syndrome.

    Mang, Niculina / Vizitiu, Anda C / Anghel, Andrei

    The Journal of international medical research

    2019  Band 47, Heft 8, Seite(n) 3757–3762

    Mesh-Begriff(e) Adolescent ; Blood Cell Count ; Case-Control Studies ; Child ; Child, Preschool ; Down Syndrome/blood ; Down Syndrome/pathology ; Female ; Follow-Up Studies ; Humans ; Infant ; Male ; Prognosis ; Retrospective Studies
    Sprache Englisch
    Erscheinungsdatum 2019-05-27
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 184023-x
    ISSN 1473-2300 ; 0300-0605 ; 0142-2596
    ISSN (online) 1473-2300
    ISSN 0300-0605 ; 0142-2596
    DOI 10.1177/0300060519850397
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  7. Artikel ; Online: Factors Impacting the Reduction in Neophobia Prevalence in Phenylketonuria Patients.

    Bugi, Meda-Ada / Jugănaru, Iulius / Isac, Raluca / Simina, Iulia-Elena / Munteanu, Andrei-Ioan / Mang, Niculina / Brad, Georgiana-Flavia / Nicoară, Delia-Maria / Cîrnatu, Daniela / Mărginean, Otilia

    Nutrients

    2024  Band 16, Heft 6

    Abstract: Food neophobia (FN), the fear of sampling new foods, can have a significant impact on children's eating habits. Children with phenylketonuria (PKU), a hereditary condition that inhibits the body's capacity to metabolize phenylalanine, should take this ... ...

    Abstract Food neophobia (FN), the fear of sampling new foods, can have a significant impact on children's eating habits. Children with phenylketonuria (PKU), a hereditary condition that inhibits the body's capacity to metabolize phenylalanine, should take this attitude with caution. Patients with PKU must follow a rigorous phenylalanine (Phe)-restricted diet to avoid brain malfunction that can include intellectual disability, seizures, and behavioral difficulties. The novelty of our work stems from the fact that we explored the origins of this incorrect intake pattern, which exacerbates PKU patients' already fragile health. We conducted a cross-sectional study on 34 previously diagnosed phenylketonuria patients and a control group ranging in age from 7 months to 40 years, with a sex ratio of M/F 2:1. The Food Neophobia Scale (FNS) was used to determine neophobia. We used JASP (version 0.18.1) statistical analysis to examine the relationship between neophobia and PKU condition, age and nutritional status at the time of study, diet compliance, parental educational level, period from birth to PKU diagnosis, and environmental (rural/urban) provenience of PKU patients. According to the data, 61.76% of patients with PKU were neophobic, as were 70.57% of the control group. Food neophobia was associated with PKU patients' present age, the period from birth to PKU diagnosis, and parental educational level.
    Mesh-Begriff(e) Child ; Humans ; Cross-Sectional Studies ; Prevalence ; Phenylketonurias ; Feeding Behavior ; Phenylalanine
    Chemische Substanzen Phenylalanine (47E5O17Y3R)
    Sprache Englisch
    Erscheinungsdatum 2024-03-07
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu16060768
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  8. Buch: Mathematik im Alltag

    Mang, Nathalie

    differenzierte Arbeitsblätter für den Mathematikunterricht ; 5./6. Klasse ; [Gymnasium]

    (Bergedorfer Unterrichtsideen)

    2012  

    Verfasserangabe Nathalie Mang
    Serientitel Bergedorfer Unterrichtsideen
    Schlagwörter Mathematikunterricht ; Unterstufe
    Sprache Deutsch
    Umfang 85 S., Ill., graph. Darst.
    Ausgabenhinweis 1. Aufl.
    Verlag Persen
    Erscheinungsort Buxtehude
    Dokumenttyp Buch
    ISBN 3403232239 ; 9783403232230
    Datenquelle Katalog der Technische Informationsbibliothek Hannover

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  9. Artikel: Implementation of IV Push Antibiotics for Outpatients During a National Fluid Shortage Following Hurricane Maria.

    Yagnik, Kruti J / Brown, L Steven / Saad, Hala A / Alvarez, Kristin / Mang, Norman / Bird, Cylaina E / Cerise, Fred / Bhavan, Kavita P

    Open forum infectious diseases

    2022  Band 9, Heft 5, Seite(n) ofac117

    Abstract: Background: Prior to the introduction of intravenous (IV) drip infusion, most IV drugs were delivered in a syringe bolus push. However, intravenous drip infusions subsequently became the standard of care. Puerto Rico is the largest supplier of IV fluid ... ...

    Abstract Background: Prior to the introduction of intravenous (IV) drip infusion, most IV drugs were delivered in a syringe bolus push. However, intravenous drip infusions subsequently became the standard of care. Puerto Rico is the largest supplier of IV fluid bags and in the aftermath of Hurricane Maria, there was a nationwide fluid bag shortage. This shortage required stewardship measures to maintain the operation of the self-administered outpatient parenteral antimicrobial therapy (OPAT) program at Parkland Health.
    Methods: Parkland pharmacists evaluated all self-administered antimicrobials for viability of administration as an IV syringe bolus push (IVP) instead of an IV-drip infusion. Medications deemed appropriate were transitioned to IVP. The hospital EMR was used to identify patients discharged to the OPAT clinic using all methods of parenteral drug delivery. Data was collected for patient demographics, patient satisfaction, and clinical outcomes. Finally cost of care was calculated for IVP and IV drip administration.
    Results: One-hundred and thirteen self-administered IVP and 102 self-administered IV drip treatment courses were identified during the study period. Individuals using IVP had a statistically significant decrease in hospital length of stay. Patient satisfaction was greater with IVP and IVP saved 504 liters of normal saline resulting in a savings of $43,652 over 6 months. The 30-day readmission rate and mortality were similar.
    Conclusion: The abrupt IV fluid shortage following a natural disaster led to implementation of a high value care model that improved efficiency, reduced costs, and did not affect safety or efficacy.
    Sprache Englisch
    Erscheinungsdatum 2022-03-21
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofac117
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  10. Artikel ; Online: Understanding short-term transmission dynamics of methicillin-resistant

    Wolfensberger, Aline / Mang, Nora / Gibson, Kristen E / Gontjes, Kyle / Cassone, Marco / Brugger, Silvio D / Mody, Lona / Sax, Hugo

    Infection control and hospital epidemiology

    2021  Band 43, Heft 9, Seite(n) 1147–1154

    Abstract: Objective: Little is known about the short-term dynamics of methicillin-resistant : Design: Observational pilot study.: Setting: Two hospitals, hospital 1 in Zurich, Switzerland, and hospital 2 in Ann Arbor, Michigan, United States.: Patients: ... ...

    Abstract Objective: Little is known about the short-term dynamics of methicillin-resistant
    Design: Observational pilot study.
    Setting: Two hospitals, hospital 1 in Zurich, Switzerland, and hospital 2 in Ann Arbor, Michigan, United States.
    Patients: Inpatients with MRSA colonization or infection.
    Methods: At baseline, the groin, axilla, nares, dominant hands of 10 patients and 6 environmental high-touch surfaces in their rooms were sampled. Cultures were then taken of the patient hand and high-touch surfaces 3 more times at 90-minute intervals. After each swabbing, patients' hands and surfaces were disinfected. Patient activity was assessed by interviews at hospital 1 and analysis of video footage at hospital 2. A contamination pressure score was created by multiplying the number of colonized body sites with the activity level of the patient.
    Results: In total, 10 patients colonized and/or infected with MRSA were enrolled; 40 hand samples and 240 environmental samples were collected. At baseline, 30% of hands and 20% of high-touch surfaces yielded MRSA. At follow-up intervals, 8 (27%) of 30 patient hands, and 10 (6%) of 180 of environmental sites were positive. Activity of the patient explained 7 of 10 environmental contaminations. Patients with higher contamination pressure score showed a trend toward higher environmental contamination.
    Conclusion: Environmental MRSA contamination in patient rooms was highly dynamic and was likely driven by the patient's MRSA body colonization pattern and the patient activity.
    Mesh-Begriff(e) Cross Infection/microbiology ; Hospitals ; Humans ; Methicillin-Resistant Staphylococcus aureus ; Patients' Rooms ; Staphylococcal Infections
    Sprache Englisch
    Erscheinungsdatum 2021-08-27
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Observational Study ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2021.350
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    Zs.A 1714: Hefte anzeigen Standort:
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