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  1. Article ; Online: Neutrophilic Panniculitides.

    Maniam, Ganesh B / Coakley, Anne / Huong Nguyen, Giang / Alavi, Afsaneh / Davis, Mark D P

    Dermatologic clinics

    2023  Volume 42, Issue 2, Page(s) 285–295

    Abstract: Neutrophilic panniculitides are a heterogeneous group of inflammatory disorders encompassing many different entities. This review article focuses on the epidemiology, pathogenesis, clinicopathological features, diagnosis, and treatment of selected ... ...

    Abstract Neutrophilic panniculitides are a heterogeneous group of inflammatory disorders encompassing many different entities. This review article focuses on the epidemiology, pathogenesis, clinicopathological features, diagnosis, and treatment of selected diseases. Patients often seek care due to systemic involvement, but the variable presentation of panniculitides can present a diagnostic challenge. Most therapeutic modalities for neutrophilic disorders are anecdotal at best with a notable lack of standardization of the responses to medications. There is an urgent need for a larger multi-institutional collaboration to address the unmet needs of these challenging, yet rare conditions.
    MeSH term(s) Humans ; Panniculitis/diagnosis ; Panniculitis/drug therapy ; Panniculitis/etiology
    Language English
    Publishing date 2023-09-14
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 82798-8
    ISSN 1558-0520 ; 0733-8635
    ISSN (online) 1558-0520
    ISSN 0733-8635
    DOI 10.1016/j.det.2023.08.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Margarita Burn: Recognition and Treatment of Phytophotodermatitis.

    Maniam, Ganesh / Light, Katelyn MacLeay / Wilson, Joanna

    Journal of the American Board of Family Medicine : JABFM

    2021  Volume 34, Issue 2, Page(s) 398–401

    Abstract: Phytophotodermatitis is a cutaneous reaction caused by direct contact with phototoxic agents and subsequent sunlight exposure. Furocoumarins and psoralens are 2 phototoxic agents that can cause this reaction, and these organic chemical compounds are ... ...

    Abstract Phytophotodermatitis is a cutaneous reaction caused by direct contact with phototoxic agents and subsequent sunlight exposure. Furocoumarins and psoralens are 2 phototoxic agents that can cause this reaction, and these organic chemical compounds are found in many plant species consumed by humans. Following contact exposure to such foods and ultraviolet radiation exposure via direct sunlight, phytophotodermatitis can occur. Due to the etiology of these rashes relating closely to the outdoor consumption of margaritas, the rash may be known by patients as "margarita burn." There is a classically described sequence of rash progression: erythematous macules or patches, which later become vesicles and seem similar to second-degree burns, followed by an asymptomatic hyperpigmentation. This case presents a 26-year-old female diagnosed with phytophotodermatitis following use of citrus fruits for margaritas while outdoors in direct sunlight. The diagnosis of phytophotodermatitis is often made clinically but can be complicated due to its similarity in appearance to many other common cutaneous reactions. In this patient, the differential diagnosis included solar erythema, contact dermatitis (type IV hypersensitivity reaction), polymorphic light eruption, or drug-related photosensitivity. Careful history taking is essential in not only narrowing down the differential diagnosis but also in avoiding unnecessary tests or ineffective treatments.
    MeSH term(s) Adult ; Burns ; Dermatitis, Phototoxic/diagnosis ; Dermatitis, Phototoxic/etiology ; Female ; Furocoumarins ; Humans ; Sunlight/adverse effects ; Ultraviolet Rays
    Chemical Substances Furocoumarins
    Language English
    Publishing date 2021-03-26
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2239939-2
    ISSN 1558-7118 ; 1557-2625
    ISSN (online) 1558-7118
    ISSN 1557-2625
    DOI 10.3122/jabfm.2021.02.200382
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Rectus sheath hematoma following enoxaparin administration.

    Dean, Ryan E / Maniam, Ganesh / Vo, Thien

    Proceedings (Baylor University. Medical Center)

    2020  Volume 33, Issue 3, Page(s) 460–461

    Abstract: Low-molecular-weight heparin, including enoxaparin, has efficacy comparable to that of unfractionated heparin and is considered the first-line option for thromboprophylaxis due to a decreased risk profile. This paper presents a rare case of epigastric ... ...

    Abstract Low-molecular-weight heparin, including enoxaparin, has efficacy comparable to that of unfractionated heparin and is considered the first-line option for thromboprophylaxis due to a decreased risk profile. This paper presents a rare case of epigastric artery rectus sheath hematoma following enoxaparin injection, resulting in multiorgan failure secondary to hemorrhagic shock. Discussion of this case may assist clinicians in the recognition and treatment of similar cases.
    Language English
    Publishing date 2020-05-04
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2703932-8
    ISSN 1525-3252 ; 0899-8280
    ISSN (online) 1525-3252
    ISSN 0899-8280
    DOI 10.1080/08998280.2020.1759336
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Human herpesvirus 6 meningitis in an adult.

    Maniam, Ganesh B / Wilkerson, Hannah / Milton, John Scott

    Proceedings (Baylor University. Medical Center)

    2020  Volume 33, Issue 2, Page(s) 246–247

    Abstract: Many cases of viral meningitis are idiopathic, but increased utilization of polymerase chain reaction testing has enabled physicians to better recognize rare causes of viral meningitis. This will likely continue to improve the rate of causative agent ... ...

    Abstract Many cases of viral meningitis are idiopathic, but increased utilization of polymerase chain reaction testing has enabled physicians to better recognize rare causes of viral meningitis. This will likely continue to improve the rate of causative agent identification in seemingly idiopathic viral meningitis, including this case of human herpesvirus 6 (HHV-6) meningitis in an immunocompetent adult patient. More common viral etiologies need to be excluded before diagnosing HHV-6 meningitis, as this maximizes pretest probability and therefore increases validity of a positive result. By efficiently diagnosing HHV-6 meningitis, proper treatment protocols can be initiated earlier to reduce morbidity and mortality. Given the rarity of HHV-6 meningitis in immunocompetent adults, there are no established standard treatment guidelines; previous reported cases, as well as this case, suggest that either intravenous ganciclovir or intravenous foscarnet are the most reasonable first-line treatment options.
    Language English
    Publishing date 2020-01-27
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2703932-8
    ISSN 1525-3252 ; 0899-8280
    ISSN (online) 1525-3252
    ISSN 0899-8280
    DOI 10.1080/08998280.2020.1719784
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Acquisition of Cholera Within the United States.

    Maniam, Ganesh / Nguyen, Emily N / Milton, John Scott

    Journal of investigative medicine high impact case reports

    2020  Volume 8, Page(s) 2324709620904204

    Abstract: Cholera has been woven into human history through numerous pandemics, with the most recent ongoing since 1961. Global rates of cholera continue to decline, but outbreaks continue to pose diagnostic challenges for clinicians, which delays initiation of ... ...

    Abstract Cholera has been woven into human history through numerous pandemics, with the most recent ongoing since 1961. Global rates of cholera continue to decline, but outbreaks continue to pose diagnostic challenges for clinicians, which delays initiation of treatment and prolongs the disease course. Despite millions of infections and thousands of deaths worldwide each year, cholera remains rare in the United States, with the few cases each year usually being the result of pathogen acquisition while the patient traveled abroad. This article presents a unique case of cholera acquired in the United States, which emphasizes the necessary vigilance of symptom recognition, in the context of appropriate clinical investigation, in ensuring that the patient had a full recovery. Cholera in the United States is exceedingly rare, yet effective diagnosis with early initiation of treatment is known to reduce mortality and shorten disease course. While other more common diagnoses must definitely be excluded first, it is important for cholera to be kept on the differential for patients presenting with treatment refractory, watery diarrhea causing hypotension. This case of a patient with a recent travel history to Hawaii and infection with cholera underscores the importance of investigative medicine and clinical expertise in optimizing patient care, even when presented with rare illnesses.
    MeSH term(s) Cholera/diagnosis ; Diarrhea/microbiology ; Female ; Hawaii ; Humans ; Middle Aged ; Travel ; United States ; Vibrio cholerae/genetics
    Language English
    Publishing date 2020-02-04
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2710326-2
    ISSN 2324-7096 ; 2324-7096
    ISSN (online) 2324-7096
    ISSN 2324-7096
    DOI 10.1177/2324709620904204
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Extrapulmonary sarcoidosis in an atypical patient demographic.

    Modi, Trisha / Maniam, Ganesh / Quirch, Miguel / Warraich, Irfan / Rehman, Shabnam

    Proceedings (Baylor University. Medical Center)

    2020  Volume 34, Issue 1, Page(s) 151–152

    Abstract: Although it typically presents with cough and dyspnea due to pulmonary involvement, sarcoidosis is a multisystem granulomatous disease and therefore may present with extrapulmonary manifestations. Cutaneous manifestations are common, while hepatic ... ...

    Abstract Although it typically presents with cough and dyspnea due to pulmonary involvement, sarcoidosis is a multisystem granulomatous disease and therefore may present with extrapulmonary manifestations. Cutaneous manifestations are common, while hepatic sarcoidosis is uncommon and osseous manifestations are exceedingly rare. This article describes osseous, hepatic, and cutaneous manifestations due to sarcoidosis. The patient was diagnosed with sarcoidosis, treated with a dynamic hip screw implant with a derotational screw, and discharged on a new medication regimen: vitamin D, calcium supplements, alendronate, methotrexate, and hydroxychloroquine.
    Language English
    Publishing date 2020-10-12
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2703932-8
    ISSN 1525-3252 ; 0899-8280
    ISSN (online) 1525-3252
    ISSN 0899-8280
    DOI 10.1080/08998280.2020.1824963
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Implementation of a pilot medical student mentoring program for premedical students and its effects on premedical student attitudes.

    Maniam, Ganesh / Dean, Ryan / Urban, Robert S / Williams, Simon

    Proceedings (Baylor University. Medical Center)

    2020  Volume 33, Issue 3, Page(s) 346–349

    Abstract: As the medical school admissions process becomes increasingly competitive, there is an increased mental and emotional burden on undergraduate premedical students due to uncertainty about acceptance. Mentors in Medicine is a mentoring program between ... ...

    Abstract As the medical school admissions process becomes increasingly competitive, there is an increased mental and emotional burden on undergraduate premedical students due to uncertainty about acceptance. Mentors in Medicine is a mentoring program between Texas Tech University Health Sciences Center and Texas Tech University students; the data demonstrate that this program can alleviate some negative emotional aspects faced by premedical students on their journey to medical school. The program interventions include establishing mentor-mentee relationships between medical students and premedical students, hosting various events to encourage dialogue, and promoting communication efforts from medical mentors. These interventions were found to significantly decrease feelings of anxiety or nervousness, as well as feelings of doubt or insecurity. These results may provide a framework for similar medical-premedical mentoring programs at other institutions.
    Language English
    Publishing date 2020-03-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2703932-8
    ISSN 1525-3252 ; 0899-8280
    ISSN (online) 1525-3252
    ISSN 0899-8280
    DOI 10.1080/08998280.2020.1743603
    Database MEDical Literature Analysis and Retrieval System OnLINE

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