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  1. AU="Manjila, Sunil"
  2. AU="Gaviria-Cantin, Tania"
  3. AU="Pickett, Brett E"
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  6. AU="Tremblay, Cyntia"
  7. AU="Sharafeldin, Tamer A"
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  14. AU="Sedor, John R."
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  18. AU="Castano-Duque, Lina"
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  38. AU="Olszewska, Zuzanna"
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  41. AU="Gangavarapu, Sridevi"
  42. AU="Hussein, Hazem Abdelwaheb"
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  1. Article: 30-day sepsis risk after laminectomy for resection of intradural extramedullary (IDEM) tumors based on NSQIP database: a critical appraisal.

    Varghese, Vineesh K / Kutty, Shankar A / Manjila, Sunil

    Journal of spine surgery (Hong Kong)

    2022  Volume 8, Issue 3, Page(s) 296–299

    Language English
    Publishing date 2022-09-23
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2874556-5
    ISSN 2414-4630 ; 2414-469X
    ISSN (online) 2414-4630
    ISSN 2414-469X
    DOI 10.21037/jss-22-58
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  2. Article ; Online: Corrigendum to "Robotic Instruments Inside the MRI Bore: Key Concepts and Evolving Paradigms in Imaging-Enhanced Cranial Neurosurgery" [World Neurosurgery 176 (2023) 127-139/20021].

    Manjila, Sunil / Rosa, Benoit / Price, Karl / Manjila, Rehan / Mencattelli, Margherita / Dupont, Pierre E

    World neurosurgery

    2023  Volume 179, Page(s) 99

    Language English
    Publishing date 2023-09-05
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2023.08.059
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    Zs.A 1159: Show issues Location:
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  3. Article ; Online: Robotic Instruments Inside the MRI Bore: Key Concepts and Evolving Paradigms in Imaging-enhanced Cranial Neurosurgery.

    Manjila, Sunil / Rosa, Benoit / Price, Karl / Manjila, Rehan / Mencattelli, Margherita / Dupont, Pierre E

    World neurosurgery

    2023  Volume 176, Page(s) 127–139

    Abstract: Intraoperative MRI has been increasingly used to robotically deliver electrodes and catheters into the human brain using a linear trajectory with great clinical success. Current cranial MR guided robotics do not allow for continuous real-time imaging ... ...

    Abstract Intraoperative MRI has been increasingly used to robotically deliver electrodes and catheters into the human brain using a linear trajectory with great clinical success. Current cranial MR guided robotics do not allow for continuous real-time imaging during the procedure because most surgical instruments are not MR-conditional. MRI guided robotic cranial surgery can achieve its full potential if all the traditional advantages of robotics (such as tremor-filtering, precision motion scaling, etc.) can be incorporated with the neurosurgeon physically present in the MRI bore or working remotely through controlled robotic arms. The technological limitations of design optimization, choice of sensing, kinematic modeling, physical constraints, and real-time control had hampered early developments in this emerging field, but continued research and development in these areas over time has granted neurosurgeons far greater confidence in using cranial robotic techniques. This article elucidates the role of MR-guided robotic procedures using clinical devices like NeuroBlate and Clearpoint that have several thousands of cases operated in a "linear cranial trajectory" and planned clinical trials, such as LAANTERN for MR guided robotics in cranial neurosurgery using LITT and MR-guided putaminal delivery of AAV2 GDNF in Parkinson's disease. The next logical improvisation would be a steerable curvilinear trajectory in cranial robotics with added DOFs and distal tip dexterity to the neurosurgical tools. Similarly, the novel concept of robotic actuators that are powered, imaged, and controlled by the MRI itself is discussed in this article, with its potential for seamless cranial neurosurgery.
    MeSH term(s) Humans ; Neurosurgery ; Neurosurgical Procedures/methods ; Robotics ; Robotic Surgical Procedures/methods ; Magnetic Resonance Imaging
    Language English
    Publishing date 2023-01-11
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2023.01.025
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  4. Article ; Online: Fourth-generation bypass and flow reversal to treat a symptomatic giant dolichoectatic basilar trunk aneurysm.

    Graffeo, Christopher S / Srinivasan, Visish M / Manjila, Sunil / Lawton, Michael T

    Acta neurochirurgica

    2022  Volume 164, Issue 11, Page(s) 2887–2892

    Abstract: Background: Giant dolichoectatic basilar trunk aneurysms have an unfavorable natural history and are associated with high morbidity, but their neurosurgical treatment is complex and challenging.: Methods: Flow reversal reconstruction with fourth- ... ...

    Abstract Background: Giant dolichoectatic basilar trunk aneurysms have an unfavorable natural history and are associated with high morbidity, but their neurosurgical treatment is complex and challenging.
    Methods: Flow reversal reconstruction with fourth-generation bypass and proximal vertebral artery clip occlusion is performed via orbitozygomatic craniotomy with the Kawase approach under rapid ventricular pacing.
    Conclusion: Fourth-generation bypass is an innovative, technically challenging, and clinically effective tool in the treatment armamentarium for giant dolichoectatic basilar trunk aneurysms.
    MeSH term(s) Humans ; Basilar Artery/diagnostic imaging ; Basilar Artery/surgery ; Intracranial Aneurysm/diagnostic imaging ; Intracranial Aneurysm/surgery ; Vertebral Artery/surgery ; Microsurgery ; Neurosurgical Procedures
    Language English
    Publishing date 2022-07-01
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-022-05292-w
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  5. Article ; Conference proceedings: Comparative Study of Morphometric Analysis Between Endoscopic Endonasal and Midline Suboccipital Subtonsillar Approaches to the Jugular Tubercle

    Gosal, Jaskaran Singh / Bhuskute, Govind / Alsavaf, Mohammad Bilal / Manjila, Sunil / Carrau, Ricardo / Prevedello, Daniel M.

    Journal of Neurological Surgery Part B: Skull Base

    2024  Volume 85, Issue S 01

    Event/congress 33rd Annual Meeting North American Skull Base Society, Atlanta Marriott Marquis Atlanta, Georgia, United States, 2024-02-16
    Language English
    Publishing date 2024-02-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 2654269-9
    ISSN 2193-634X ; 2193-6331
    ISSN (online) 2193-634X
    ISSN 2193-6331
    DOI 10.1055/s-0044-1780029
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    Zs.A 3425: Show issues Location:
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  6. Article ; Online: A Eulogy for Dr. Setti S. Rengachary, 1937-2008

    Manjila Sunil

    Neurology India, Vol 56, Iss 4, Pp 501-

    2008  Volume 502

    Keywords Neurology. Diseases of the nervous system ; RC346-429 ; Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Neurology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2008-01-01T00:00:00Z
    Publisher Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Management of Osteoporosis and Spinal Fractures: Contemporary Guidelines and Evolving Paradigms.

    Imamudeen, Nasvin / Basheer, Amjad / Iqbal, Anoop Mohamed / Manjila, Nihal / Haroon, Nisha Nigil / Manjila, Sunil

    Clinical medicine & research

    2022  Volume 20, Issue 2, Page(s) 95–106

    Abstract: Physicians involved in treating spine fractures secondary to osteopenia and osteoporosis should know the pathogenesis and current guidelines on managing the underlying diminished bone mineral density, as worldwide fracture prevention campaigns are ... ...

    Abstract Physicians involved in treating spine fractures secondary to osteopenia and osteoporosis should know the pathogenesis and current guidelines on managing the underlying diminished bone mineral density, as worldwide fracture prevention campaigns are trailing behind in meeting their goals. This is a narrative review exploring the various imaging and laboratory tests used to diagnose osteoporotic fractures and a comprehensive compilation of contemporary medical and surgical management. We have incorporated salient recommendations from the Endocrine Society, the American Association of Clinical Endocrinology (AACE), and the American Society for Bone and Mineral Research (ASBMR). The use of modern scoring systems such as Fracture Risk Assessment Tool (FRAX®) for evaluating fracture risk in osteoporosis with a 10-year probability of hip fracture and major fractures in the spine, forearm, hip, or shoulder is highlighted. This osteoporosis risk assessment tool can be easily incorporated into the preoperative bone health optimization strategies, especially before elective spine surgery in osteoporotic patients. The role of primary surgical intervention for vertebral compression fracture and secondary fracture prevention with pharmacological therapy is described, with randomized clinical trial-based wisdom on its timing and dosage, drug holiday, adverse effects, and relevant evidence-based literature. We also aim to present an evidence-based clinical management algorithm for treating osteoporotic vertebral body compression fractures, tumor-induced osteoporosis, or hardware stabilization in elderly trauma patients in the setting of their impaired bone health. The recent guidelines and recommendations on surgical intervention by various medical societies are covered, along with outcome studies that reveal the efficacy of cement augmentation of vertebral compression fractures via vertebroplasty and balloon kyphoplasty versus conservative medical management in the elderly population.
    MeSH term(s) Aged ; Fractures, Compression/diagnosis ; Fractures, Compression/etiology ; Fractures, Compression/therapy ; Humans ; Kyphoplasty/adverse effects ; Kyphoplasty/methods ; Osteoporosis/complications ; Osteoporosis/diagnosis ; Osteoporosis/therapy ; Osteoporotic Fractures/diagnosis ; Osteoporotic Fractures/prevention & control ; Randomized Controlled Trials as Topic ; Spinal Fractures/diagnosis ; Spinal Fractures/epidemiology ; Spinal Fractures/therapy ; Treatment Outcome ; Vertebroplasty/adverse effects ; Vertebroplasty/methods
    Language English
    Publishing date 2022-04-27
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2303793-3
    ISSN 1554-6179 ; 1539-4182
    ISSN (online) 1554-6179
    ISSN 1539-4182
    DOI 10.3121/cmr.2021.1612
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    Zs.A 6719: Show issues Location:
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  8. Article: De Novo Glioblastoma Masqueraded within a Hemispheric Dural Meningiomatosis: Rare Imaging Findings and Rationale for Two-Staged Resection.

    Zacharewski, Nicholas / Movahed-Ezazi, Misha / Song, Xianyuan / Mehta, Tapan / Manjila, Sunil

    Journal of neurological surgery reports

    2022  Volume 83, Issue 2, Page(s) e44–e49

    Abstract: ... ...

    Abstract Introduction
    Language English
    Publishing date 2022-06-01
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2653397-2
    ISSN 2193-6366 ; 2193-6358
    ISSN (online) 2193-6366
    ISSN 2193-6358
    DOI 10.1055/s-0042-1749215
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    Zs.A 6973: Show issues Location:
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  9. Article ; Conference proceedings: Endoscopic Sublabial Contralateral Transmaxillary versus Precaruncular Contralateral Medial Transorbital Corridor as a Multiport Endoscopic Endonasal Approach to Petrous Apex

    Gosal, Jaskaran Singh / Bhuskute, Govind S. / Alsavaf, Mohammad Bilal / Manjila, Sunil / Carrau, Ricardo L. / Prevedello, Daniel M.

    Journal of Neurological Surgery Part B: Skull Base

    2024  Volume 85, Issue S 01

    Event/congress 33rd Annual Meeting North American Skull Base Society, Atlanta Marriott Marquis Atlanta, Georgia, United States, 2024-02-16
    Language English
    Publishing date 2024-02-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 2654269-9
    ISSN 2193-634X ; 2193-6331
    ISSN (online) 2193-634X
    ISSN 2193-6331
    DOI 10.1055/s-0044-1779904
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    Zs.A 3425: Show issues Location:
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  10. Article ; Online: Morphometric Comparison of Endoscopic Endonasal Transpterygoid and Precaruncular Contralateral Medial Transorbital Approaches to Sphenoid Sinus Lateral Recess.

    Bhuskute, Govind S / Gosal, Jaskaran Singh / Alsavaf, Mohammad Bilal / Abouammo, Moataz D / Manjila, Sunil / Kandregula, Sandeep / Nayyar, Ashish K / Jha, Deepak K / Carrau, Ricardo L / Prevedello, Daniel M

    Operative neurosurgery (Hagerstown, Md.)

    2024  

    Abstract: Background and objectives: The endoscopic endonasal transpterygoid approach (TPA), minimally invasive compared with the sublabial transmaxillary and transcranial approaches, still accounts for morbidity in benign lateral recess of sphenoid sinus (LRSS) ... ...

    Abstract Background and objectives: The endoscopic endonasal transpterygoid approach (TPA), minimally invasive compared with the sublabial transmaxillary and transcranial approaches, still accounts for morbidity in benign lateral recess of sphenoid sinus (LRSS) pathologies. Others have suggested an alternative route to the LRSS, the endoscopic contralateral medial transorbital approach (cMTO). However, no quantitative evidence exists to support the clinical application of this approach. This cadaveric study, in a controlled laboratory setting, provides a morphometric comparison of the TPA and cMTO for accessing the LRSS. The study also details the anatomy and technical nuances for optimizing the cMTO corridor.
    Methods: Ten fresh preinjected human cadaveric specimens (20 sides) were dissected with neuronavigation, completing endoscopic cMTO and TPA on each side. Four parameters-working distance to lateral recess, surgical exposure area, angle of attack (AoA), and surgical freedom-were measured for each approach. Relevant osteological measurements in 10 dried human skulls were recorded.
    Results: The mean distance from the superior margin of the lacrimal sac impression to the inferior margin of the trochlear fossa was 10.29 ± 1.13 mm, and that from the anterior ethmoidal artery foramina to the posterior lacrimal crest was 9.63 ± 1.23 mm. The mean exposure area around the LRSS was significantly higher in TPA (614.09 ± 40.38 mm2) than in cMTO (391.19 ± 59.01 mm2, P = .001). The mean AoA was 9.83° and 10.24° in the cMTO and TPA, respectively, in the craniocaudal direction (P = .529). In the horizontal plane, it was 9.29° and 10.76° (P = .012). There was no significant difference in surgical freedom between the cMTO and TPA (804.61 and 806.05 mm3, respectively; P = .993).
    Conclusion: Although comparatively limited exposure area, the cMTO approach has a similar AoA and surgical freedom as TPA and offers better visualization and ergonomic advantages. cMTO provides a feasible, less morbid, multiport technique for benign sphenoid sinus lateral recess pathologies.
    Language English
    Publishing date 2024-01-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2767575-0
    ISSN 2332-4260 ; 2332-4252
    ISSN (online) 2332-4260
    ISSN 2332-4252
    DOI 10.1227/ons.0000000000001053
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