LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Erweiterte Suche

Ihre letzten Suchen

  1. AU="Manning, Nyla"
  2. AU="Sindkar, Anushka"
  3. AU=Rodieux Frdrique
  4. AU="Tote, Sachin"

Suchergebnis

Treffer 1 - 4 von insgesamt 4

Suchoptionen

  1. Artikel ; Online: Effect of Porins and bla

    Balabanian, Gregory / Rose, Michael / Manning, Nyla / Landman, David / Quale, John

    Microbial drug resistance (Larchmont, N.Y.)

    2018  Band 24, Heft 7, Seite(n) 877–881

    Abstract: Imipenem with relebactam is a novel β-lactam-β-lactamase inhibitor that has activity against most KPC-producing Enterobacteriaceae. Using 10 isolates of KPC-possessing Klebsiella pneumoniae, we assessed the relationship between imipenem-relebactam ... ...

    Abstract Imipenem with relebactam is a novel β-lactam-β-lactamase inhibitor that has activity against most KPC-producing Enterobacteriaceae. Using 10 isolates of KPC-possessing Klebsiella pneumoniae, we assessed the relationship between imipenem-relebactam minimum inhibitory concentrations (MICs) and mechanisms known to contribute to antimicrobial resistance. The effect of adding a second agent was assessed by time-kill experiments. Mutations affecting the genes encoding porins ompK35 and ompK36 and identification of β-lactamases were assessed by PCR. Expression of bla
    Mesh-Begriff(e) Anti-Bacterial Agents/pharmacology ; Azabicyclo Compounds/pharmacology ; Bacterial Proteins/genetics ; Drug Combinations ; Drug Resistance, Bacterial/drug effects ; Drug Resistance, Bacterial/genetics ; Gene Expression Regulation, Bacterial/drug effects ; Gene Expression Regulation, Bacterial/genetics ; Humans ; Imipenem/pharmacology ; Klebsiella Infections/drug therapy ; Klebsiella pneumoniae/drug effects ; Klebsiella pneumoniae/genetics ; Microbial Sensitivity Tests/methods ; Porins/genetics ; beta-Lactamases
    Chemische Substanzen Anti-Bacterial Agents ; Azabicyclo Compounds ; Bacterial Proteins ; Drug Combinations ; Porins ; MK-7655 (1OQF7TT3PF) ; Imipenem (71OTZ9ZE0A) ; beta-Lactamases (EC 3.5.2.6)
    Sprache Englisch
    Erscheinungsdatum 2018-05-21
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1290490-9
    ISSN 1931-8448 ; 1076-6294
    ISSN (online) 1931-8448
    ISSN 1076-6294
    DOI 10.1089/mdr.2018.0065
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  2. Artikel ; Online: Activity of Ceftazidime-Avibactam Against Clinical Isolates of Klebsiella pneumoniae, Including KPC-Carrying Isolates, Endemic to New York City.

    Manning, Nyla / Balabanian, Gregory / Rose, Michael / Landman, David / Quale, John

    Microbial drug resistance (Larchmont, N.Y.)

    2018  Band 24, Heft 1, Seite(n) 35–39

    Abstract: In this report, we examined the (1) activity of ceftazidime-avibactam against clinical isolates Klebsiella pneumoniae, including those harboring ... ...

    Abstract In this report, we examined the (1) activity of ceftazidime-avibactam against clinical isolates Klebsiella pneumoniae, including those harboring bla
    Mesh-Begriff(e) Amikacin/pharmacology ; Anti-Bacterial Agents/pharmacology ; Azabicyclo Compounds/pharmacology ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Ceftazidime/pharmacology ; Drug Combinations ; Drug Synergism ; Endemic Diseases ; Gene Expression Regulation, Bacterial ; Humans ; Klebsiella Infections/drug therapy ; Klebsiella Infections/epidemiology ; Klebsiella Infections/microbiology ; Klebsiella pneumoniae/drug effects ; Klebsiella pneumoniae/genetics ; Klebsiella pneumoniae/isolation & purification ; Klebsiella pneumoniae/metabolism ; Microbial Sensitivity Tests ; Mutation ; New York City/epidemiology ; Polymyxin B/pharmacology ; Porins/genetics ; Porins/metabolism ; beta-Lactamases/genetics ; beta-Lactamases/metabolism
    Chemische Substanzen Anti-Bacterial Agents ; Azabicyclo Compounds ; Bacterial Proteins ; Drug Combinations ; OmpK35 porin, Klebsiella pneumoniae ; Porins ; avibactam, ceftazidime drug combination ; Polymyxin B (1404-26-8) ; Amikacin (84319SGC3C) ; Ceftazidime (9M416Z9QNR) ; beta-Lactamases (EC 3.5.2.6) ; beta-lactamase KPC-2, Klebsiella pneumoniae (EC 3.5.2.6) ; beta-lactamase KPC-3, Klebsiella pneumoniae (EC 3.5.2.6)
    Sprache Englisch
    Erscheinungsdatum 2018-01
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1290490-9
    ISSN 1931-8448 ; 1076-6294
    ISSN (online) 1931-8448
    ISSN 1076-6294
    DOI 10.1089/mdr.2016.0293
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  3. Artikel: Chronic sinusitis-associated antrolith.

    Manning, Nyla / Wu, Patrick / Preis, Jana / Ojeda-Martinez, Hector / Chan, Michael

    IDCases

    2018  Band 14, Seite(n) e00467

    Abstract: An antrolith is a calcified mass found in the nasal cavity or sinus, usually maxillary, described in literature as a rare phenomenon. Its presenting symptoms are variable and include symptoms associated with chronic sinusitis. We describe a 66 year old ... ...

    Abstract An antrolith is a calcified mass found in the nasal cavity or sinus, usually maxillary, described in literature as a rare phenomenon. Its presenting symptoms are variable and include symptoms associated with chronic sinusitis. We describe a 66 year old man with chronic sinusitis who presented with facial pain and epistaxis and upon further evaluation was found to have an antrolith of the left maxillary sinus.
    Sprache Englisch
    Erscheinungsdatum 2018-11-03
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article ; Case Reports
    ZDB-ID 2745454-X
    ISSN 2214-2509
    ISSN 2214-2509
    DOI 10.1016/j.idcr.2018.e00467
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  4. Artikel ; Online: Administration of a survey to evaluate the attitudes of house staff physicians towards antimicrobial resistance and the antimicrobial stewardship programme at a community teaching hospital.

    Venugopalan, Veena / Trustman, Nathan / Manning, Nyla / Hashem, Nehal / Berkowitz, Leonard / Hidayat, Levita

    Journal of global antimicrobial resistance

    2016  Band 4, Seite(n) 21–27

    Abstract: Antimicrobial stewardship programmes (ASPs) are used in numerous institutions in an effort to promote safe and effective antimicrobial use. The objectives of this study were to (i) assess physicians' perceptions, attitudes and knowledge about ... ...

    Abstract Antimicrobial stewardship programmes (ASPs) are used in numerous institutions in an effort to promote safe and effective antimicrobial use. The objectives of this study were to (i) assess physicians' perceptions, attitudes and knowledge about antimicrobial use, resistance and the ASP at The Brooklyn Hospital Center (TBHC) and (ii) measure physicians' beliefs and attitudes to the current system of prior authorisation of antimicrobials. A 75-item, anonymous, voluntary, traditional paper and pencil survey was distributed to resident physicians at TBHC. Multiple-choice, 5-point Likert scale and knowledge-based questions were utilised. Of the 261 residents, 129 (49%) completed the survey. The respondents significantly believed that antibiotics are overused more frequently nationally vs. locally [117/129 (91%) vs. 91/129 (71%); P=0.0001]. Although 49% (63/129) felt that other providers overprescribe antibiotics, only 26% (34/129) agreed that they themselves were contributing to the current problem (P=0.0003). Fifty-seven percent of respondents agreed that individual patient care is improved by having an antibiotic approval programme; however, 45% of respondents reported that the antibiotic approval programme limits their autonomy in choosing antibiotics. Compared with surgical residents, medical residents were more likely (33% vs. 13%; P=0.02) to feel that the antibiotic approval programme forced them to choose an inappropriate antibiotic. On the antibiotic knowledge assessment segment of the survey, there was no difference in score when stratified by specialty or years of postgraduate training. Based on the survey results, house staff are supportive of antimicrobial stewardship and feel that the ASP is valuable for patient care.
    Mesh-Begriff(e) Anti-Bacterial Agents ; Antimicrobial Stewardship ; Attitude of Health Personnel ; Drug Resistance, Bacterial ; Health Knowledge, Attitudes, Practice ; Hospitals, Teaching ; Humans ; New York City ; Physicians ; Practice Patterns, Physicians' ; Surveys and Questionnaires
    Chemische Substanzen Anti-Bacterial Agents
    Sprache Englisch
    Erscheinungsdatum 2016-02-08
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2710046-7
    ISSN 2213-7173 ; 2213-7165
    ISSN (online) 2213-7173
    ISSN 2213-7165
    DOI 10.1016/j.jgar.2016.01.004
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

Zum Seitenanfang