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  1. Article: Meckel's diverticulum in an adult with iron deficiency.

    Kanagalingam, Gowthami / Vyas, Vrinda / Sharma, Anuj / Manocha, Divey

    Proceedings (Baylor University. Medical Center)

    2021  Volume 34, Issue 3, Page(s) 367–368

    Abstract: Meckel's diverticulum is a true diverticulum caused by the incomplete obliteration of the vitelline duct during gestation. It is the most common congenital malformation of the gastrointestinal tract. Meckel's diverticulum is a rare presentation in adults, ...

    Abstract Meckel's diverticulum is a true diverticulum caused by the incomplete obliteration of the vitelline duct during gestation. It is the most common congenital malformation of the gastrointestinal tract. Meckel's diverticulum is a rare presentation in adults, especially because symptomatic patients present in early childhood. We present a 57-year-old woman with symptomatic iron deficiency after recent nonsteroidal anti-inflammatory use. After normal upper and lower endoscopy, a capsule endoscopy showed an oozing polyp in the distal ileum. The small bowel was surgically resected, and histopathology confirmed Meckel's diverticulum as the cause of her small bowel bleeding. Rare causes such as Meckel's diverticulum should be kept in mind in the differential diagnosis for patients with suspected small bowel bleeding.
    Language English
    Publishing date 2021-01-28
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2703932-8
    ISSN 1525-3252 ; 0899-8280
    ISSN (online) 1525-3252
    ISSN 0899-8280
    DOI 10.1080/08998280.2020.1871163
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Signet Ring Cell Carcinoma Presenting as a Necrotic Duodenocolic Fistulizing Mass.

    Naidoo, Shiva F / Shariff, Hamzah / Lowe, Dhruv / Goyal, Abhinav / Manocha, Divey

    Cureus

    2023  Volume 15, Issue 4, Page(s) e38361

    Abstract: A 79-year-old female was referred for endoscopic evaluation after a positive fecal occult blood test. There was a long-standing history of iron deficiency anemia, weight loss with intermittent touts of intractable vomiting, and nausea. ... ...

    Abstract A 79-year-old female was referred for endoscopic evaluation after a positive fecal occult blood test. There was a long-standing history of iron deficiency anemia, weight loss with intermittent touts of intractable vomiting, and nausea. Esophagogastroduodenoscopy revealed a secondary lumen between the duodenum and transverse colon with necrotic mucosa and a blind opening. Subsequent colonoscopy revealed similar necrotic mucosa at the transverse colon and fistula formation with communication into the duodenum. Signet ring cell carcinoma (SRCC) was evident in histologic analysis. SRCC carries a poorer prognosis than other variants of colorectal carcinoma (CRC). Proposed mechanisms of increased mucin production can lead to mucosal wall destruction and have profound manifestations, such as in our patient with duodenocolic fistula.
    Language English
    Publishing date 2023-04-30
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.38361
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Amphetamine, Dextroamphetamine Mixed Salts-Associated Ischemic Colitis.

    Bernshteyn, Michelle / Masood, Umair / Mirchia, Kanish / Manocha, Divey

    American journal of therapeutics

    2020  

    Language English
    Publishing date 2020-06-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1280786-2
    ISSN 1536-3686 ; 1075-2765
    ISSN (online) 1536-3686
    ISSN 1075-2765
    DOI 10.1097/MJT.0000000000001172
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Gastrointestinal Hemorrhage From Esophageal Dissecans Superficialis After the Initiation of a Tyrosine Kinase Inhibitor.

    Kanagalingam, Gowthami / Sostre Santiago, Vanessa / Vyas, Vrinda / Manocha, Divey

    Cureus

    2021  Volume 13, Issue 7, Page(s) e16471

    Abstract: Esophagitis dissecans superficialis (EDS) is described as the peeling of squamous mucosa of the esophagus with regurgitation of esophageal casts. It is a rare endoscopic finding associated with chemical irritants, autoimmune disorders, or medications. ... ...

    Abstract Esophagitis dissecans superficialis (EDS) is described as the peeling of squamous mucosa of the esophagus with regurgitation of esophageal casts. It is a rare endoscopic finding associated with chemical irritants, autoimmune disorders, or medications. Most patients are asymptomatic but clinical manifestations can include dysphagia, heartburn, bleeding, or vomiting. In this report, we present a case of a 70-year-old man with a previous history of small cell lung and hepatocellular carcinoma for which he had undergone chemoradiation and immunotherapy. He had presented with upper gastrointestinal hemorrhage manifested as coffee ground emesis. Endoscopic findings were consistent with EDS. No recurrence of his gastrointestinal hemorrhage was observed after acid-suppressive therapy. With our case report, we aim to increase awareness for EDS as a differential diagnosis for gastrointestinal hemorrhage.
    Language English
    Publishing date 2021-07-19
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.16471
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Necrobiotic Pulmonary Nodules in Ulcerative Colitis: Not Just a "Crohnic" Phenomenon.

    Mukherjee, Samiran / Harne, Prateek / Mirchia, Kanish / Sharma, Anuj / Manocha, Divey

    ACG case reports journal

    2020  Volume 7, Issue 8, Page(s) e00438

    Abstract: Necrobiotic pulmonary nodules are an exceptionally rare extraintestinal manifestation of inflammatory bowel disease. Recognition is imperative because it may mimic other autoimmune pathologies such as granulomatosis with polyangiitis or sarcoidosis. We ... ...

    Abstract Necrobiotic pulmonary nodules are an exceptionally rare extraintestinal manifestation of inflammatory bowel disease. Recognition is imperative because it may mimic other autoimmune pathologies such as granulomatosis with polyangiitis or sarcoidosis. We describe a 19-year-old man with a known history of ulcerative colitis who was found to possess bilateral pulmonary nodules on computed tomography imaging. Investigations that included an extensive autoimmune and infectious workup were inconclusive. Biopsy of the nodules revealed fibrinous exudate and palisading histiocytes that confirmed the diagnosis. He was started on prednisone therapy. A follow-up computed tomography a month later revealed near complete resolution.
    Language English
    Publishing date 2020-08-20
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2814825-3
    ISSN 2326-3253
    ISSN 2326-3253
    DOI 10.14309/crj.0000000000000438
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Lemmel's Syndrome: Usual Presentation of an Unusual Diagnosis.

    Bernshteyn, Michelle / Rao, Suman / Sharma, Anuj / Masood, Umair / Manocha, Divey

    Cureus

    2020  Volume 12, Issue 4, Page(s) e7698

    Abstract: Lemmel's syndrome causes obstructive jaundice in the absence of stones or tumors. The most common cause is the presence of periampullary diverticula which arise within 2-3 cm from the ampulla of Vater. Diverticula may be extramural or intramural. Despite ...

    Abstract Lemmel's syndrome causes obstructive jaundice in the absence of stones or tumors. The most common cause is the presence of periampullary diverticula which arise within 2-3 cm from the ampulla of Vater. Diverticula may be extramural or intramural. Despite current practice of obtaining imaging studies such as ultrasound, CT, and MRI, endoscopic retrograde cholangiopancreatography (ERCP) is the gold standard diagnostic test. Lemmel's syndrome should be considered when pancreaticobiliary disease is suspected. We present a case in which our patient presented with abdominal pain, fever, and transaminitis who underwent ERCP which was successful in diagnosis of Lemmel's syndrome and its treatment. Although rare, it is imperative for physicians to recognize this syndrome in order to deliver prompt care.
    Language English
    Publishing date 2020-04-16
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.7698
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: A Therapeutic Approach to Cecal Varices.

    Kudaravalli, Pujitha / Saleem, Sheikh A / Pendela, Venkata Satish / Manocha, Divey

    ACG case reports journal

    2020  Volume 7, Issue 2, Page(s) e00315

    Abstract: Ectopic varices account for 1%-5% of all variceal bleeding episodes. The most common presentation of cecal varices is an acute episode of a massive lower gastrointestinal hemorrhage. However, cecal varices can be found incidentally and can be silent for ... ...

    Abstract Ectopic varices account for 1%-5% of all variceal bleeding episodes. The most common presentation of cecal varices is an acute episode of a massive lower gastrointestinal hemorrhage. However, cecal varices can be found incidentally and can be silent for a prolonged period of time before presenting with a massive gastrointestinal hemorrhage. Through this case of a 63-year-old woman, we would like to highlight the paucity of literature in the treatment of nonbleeding cecal varices.
    Language English
    Publishing date 2020-03-02
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2814825-3
    ISSN 2326-3253
    ISSN 2326-3253
    DOI 10.14309/crj.0000000000000315
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Small Intestinal Bacterial Overgrowth: Comprehensive Review of Diagnosis, Prevention, and Treatment Methods.

    Achufusi, Ted George O / Sharma, Anuj / Zamora, Ernesto A / Manocha, Divey

    Cureus

    2020  Volume 12, Issue 6, Page(s) e8860

    Abstract: Small intestinal bacterial overgrowth (SIBO) is a commonly diagnosed gastrointestinal disorder affecting millions of individuals throughout the United States. It refers to a condition in which there is an excess and imbalance of small intestinal bacteria. ...

    Abstract Small intestinal bacterial overgrowth (SIBO) is a commonly diagnosed gastrointestinal disorder affecting millions of individuals throughout the United States. It refers to a condition in which there is an excess and imbalance of small intestinal bacteria. Despite its prevalence, it remains underdiagnosed due to the invasive nature of diagnostic testing. Symptoms observed in SIBO, including abdominal distension, bloating, diarrhea, and gas formation, are nonspecific and can overlap with other gastrointestinal disorders. Frequently cited predisposing factors include gastric acid suppression, dysmotility, gastric bypass, and opioids. The diagnostic gold standard remains small bowel aspirate and culture. However, due to its invasive nature, it remains an unpopular method among patients and clinicians alike. Glucose and lactulose breath testing have become the go-to diagnostic method in clinical practice due to its noninvasive nature and low cost. Treatment is guided towards the eradication of bacteria in the small bowel and usually consists of a prolonged course of oral antibiotics. Due to recent advances in our understanding of the human microbiome, we are surely poised for a transformation in our approach to diagnosing and treating this condition.
    Language English
    Publishing date 2020-06-27
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.8860
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Liver Cirrhosis Secondary to Autoimmune Hepatitis in a Patient with Alpha-1 Antitrypsin ZZ Phenotype: A "Double Hit" Phenomenon.

    Hoilat, Gilles J / Khan, Ayesha / Masood, Umair / Sharma, Anuj / Manocha, Divey

    Cureus

    2021  Volume 13, Issue 1, Page(s) e12606

    Abstract: Alpha-1 antitrypsin deficiency has been known to cause pulmonary and hepatic diseases. Cirrhosis in patients with alpha-1 antitrypsin deficiency, especially in a homozygotes ZZ phenotype, has been described to occur exclusively as a congenital disease. ... ...

    Abstract Alpha-1 antitrypsin deficiency has been known to cause pulmonary and hepatic diseases. Cirrhosis in patients with alpha-1 antitrypsin deficiency, especially in a homozygotes ZZ phenotype, has been described to occur exclusively as a congenital disease. We present the case of a young 28-year-old female who was initially followed for thrombocytopenia and was found to have cirrhosis of the liver with autoimmune histological features suggesting the possibility that another "second hit" can contribute to a more rapid progression of liver disease.
    Language English
    Publishing date 2021-01-10
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.12606
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: The Black Esophagus.

    Thomas, Mathew / Sostre Santiago, Vanessa / Suhail, Fathima K / Polanco Serra, Guillermo / Manocha, Divey

    Cureus

    2021  Volume 13, Issue 10, Page(s) e18655

    Abstract: Acute esophageal necrosis (AEN), commonly referred to as black esophagus, is a rare clinical condition resulting from a combination of ischemic insult and thromboembolic injury to the esophagus. It is characterized by the circumferential black appearance ...

    Abstract Acute esophageal necrosis (AEN), commonly referred to as black esophagus, is a rare clinical condition resulting from a combination of ischemic insult and thromboembolic injury to the esophagus. It is characterized by the circumferential black appearance of the esophagus. The risk factors for the development of AEN include coronary artery disease (CAD), diabetes mellitus, hypertension, malignancy, and alcohol use disorder. The treatment is directed at correcting the underlying medical conditions, supportive measures, and gastric acid suppression. We present the case of a 60-year-old female with multiple medical comorbidities who was detected to have a black esophagus during the evaluation of anemia.
    Language English
    Publishing date 2021-10-11
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.18655
    Database MEDical Literature Analysis and Retrieval System OnLINE

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