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  1. Article: Cyclic Change in Right and Left Ventricular Systolic and Diastolic Function in Patients with Neuromuscular Disorders on Permanent Mechanical Ventilation.

    Fayssoil, Abdallah / Mansencal, Nicolas / Bergounioux, Jean / Wahbi, Karim / Stojkovic, Tanya

    Journal of personalized medicine

    2022  Volume 12, Issue 10

    Abstract: Home mechanical ventilation is classically used to treat neuromuscular patients with chronic respiratory insufficiency. Since the heart and lungs are localized in the thorax, intrathoracic pressure may directly affect heart function. Here, we report the ... ...

    Abstract Home mechanical ventilation is classically used to treat neuromuscular patients with chronic respiratory insufficiency. Since the heart and lungs are localized in the thorax, intrathoracic pressure may directly affect heart function. Here, we report the direct cyclic effects of mechanical ventilation on the right and left ventricular systolic and diastolic function in serial cases. These cases highlight the importance of performing Doppler echocardiography in patients with neuromuscular disorders, focusing on the right and left ventricular systolic and diastolic functions in the context of ventilation setting modifications or introduction.
    Language English
    Publishing date 2022-10-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662248-8
    ISSN 2075-4426
    ISSN 2075-4426
    DOI 10.3390/jpm12101694
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: High parasternal intercostal muscle thickening prior to intubation in COVID-19 infection.

    Fayssoil, Abdallah / Carlier, Robert / Mansencal, Nicolas / Lofaso, Frédéric / Annane, Djillali

    Radiology case reports

    2022  Volume 17, Issue 3, Page(s) 843–846

    Abstract: Acute hypoxemic respiratory failure (AHRF) is a major complication of COVID-19 pneumonia and parasternal intercostal muscle thickening may be used as a biomarker to assess inspiratory effort. We report the case of a high utilization of parasternal ... ...

    Abstract Acute hypoxemic respiratory failure (AHRF) is a major complication of COVID-19 pneumonia and parasternal intercostal muscle thickening may be used as a biomarker to assess inspiratory effort. We report the case of a high utilization of parasternal intercostal muscle prior to the introduction of invasive ventilation in a 66-year old male none vaccinated COVID -19 patient admitted in hospital because of AHRF.
    Language English
    Publishing date 2022-01-06
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2406300-9
    ISSN 1930-0433
    ISSN 1930-0433
    DOI 10.1016/j.radcr.2021.12.037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Diaphragm ultrasound to stratify COVID-19 patients in the emergency department?

    Fayssoil, Abdallah / Beaune, Sebastien / Davido, Benjamin / Mansencal, Nicolas

    Journal of clinical ultrasound : JCU

    2021  Volume 50, Issue 1, Page(s) 106–107

    MeSH term(s) COVID-19 ; Diaphragm/diagnostic imaging ; Emergency Service, Hospital ; Humans ; SARS-CoV-2 ; Ultrasonography
    Language English
    Publishing date 2021-10-11
    Publishing country United States
    Document type Letter
    ZDB-ID 189393-2
    ISSN 1097-0096 ; 0091-2751
    ISSN (online) 1097-0096
    ISSN 0091-2751
    DOI 10.1002/jcu.23074
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Quel est le risque de Takotsubo chez la femme ?

    Mansencal, Nicolas / Dubourg, Olivier

    Presse medicale (Paris, France : 1983)

    2018  Volume 47, Issue 9, Page(s) 817–822

    Abstract: Takotsubo cardiomyopathy preferentially affects postmenopausal women (# 90%). Takotsubo cardiomyopathy mimics an acute coronary syndrome and is defined as a transient left ventricular systolic dysfunction. Diagnosis is based on the criteria of the Mayo ... ...

    Title translation What is the risk of Takotsubo in women?
    Abstract Takotsubo cardiomyopathy preferentially affects postmenopausal women (# 90%). Takotsubo cardiomyopathy mimics an acute coronary syndrome and is defined as a transient left ventricular systolic dysfunction. Diagnosis is based on the criteria of the Mayo Clinic. Stress is found in around 80% of cases: physical stress, emotional stress, medical stress. Physical stress is less found in women. Incidence of Takotsubo cardiomyopathy is 54.9/1,000,000 inhabitants in women versus only 3.6/1,000,000 inhabitants in men. Diagnosis is based on electrocardiogram, biomarkers, echocardiography, coronary angiography and left ventricular angiography, and cardiac magnetic imaging. The complete recovery of left ventricular systolic function must be assessed, allowing to confirm the diagnosis of Takotsubo cardiomyopathy.
    MeSH term(s) Coronary Angiography ; Echocardiography ; Electrocardiography ; Female ; Heart Ventricles/diagnostic imaging ; Humans ; Postmenopause ; Risk Factors ; Sex Factors ; Takotsubo Cardiomyopathy/diagnosis ; Takotsubo Cardiomyopathy/epidemiology ; Takotsubo Cardiomyopathy/etiology
    Language French
    Publishing date 2018-09-10
    Publishing country France
    Document type Journal Article ; Review
    ZDB-ID 120943-7
    ISSN 2213-0276 ; 0032-7867 ; 0755-4982 ; 0301-1518
    ISSN (online) 2213-0276
    ISSN 0032-7867 ; 0755-4982 ; 0301-1518
    DOI 10.1016/j.lpm.2018.06.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The Right Ventricle in COVID-19 Patients.

    Fayssoil, Abdallah / Mustafic, Hazrije / Mansencal, Nicolas

    The American journal of cardiology

    2020  Volume 130, Page(s) 166–167

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/physiopathology ; Echocardiography ; Humans ; Pandemics ; Pneumonia, Viral/physiopathology ; SARS-CoV-2 ; Ventricular Dysfunction, Right/diagnostic imaging ; Ventricular Dysfunction, Right/physiopathology
    Keywords covid19
    Language English
    Publishing date 2020-06-09
    Publishing country United States
    Document type Letter
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2020.06.007
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  6. Article ; Online: Case report of a very late dual coronary stent thrombosis in a patient with coronavirus disease 2019.

    Hauguel-Moreau, Marie / Lannou, Simon / Bergez, Léa / Mansencal, Nicolas

    European heart journal. Case reports

    2021  Volume 5, Issue 6, Page(s) ytab114

    Abstract: Background: Coronavirus disease 2019 (COVID-19) is associated with hypercoagulability and a high rate of thrombosis. Few cases of coronary stent thrombosis associated with COVID-19 have been reported.: Case summary: In this report, we describe the ... ...

    Abstract Background: Coronavirus disease 2019 (COVID-19) is associated with hypercoagulability and a high rate of thrombosis. Few cases of coronary stent thrombosis associated with COVID-19 have been reported.
    Case summary: In this report, we describe the case of a 65-year-old man with a history of coronary artery disease (CAD) who was admitted following an out-of-hospital cardiac arrest related to an ST-segment elevation myocardial infarction revealing a very late dual coronary stent thrombosis of the left anterior descending and posterior descending arteries. Ten days prior to admission, he was diagnosed with COVID-19 pneumonia and treated with dexamethasone, which led to rapid clinical improvement. After resuscitation, coronary angiography revealed an acute thrombotic occlusion in the two previous drug-eluting stents (implanted in 2010 and 2018), with a high thrombus burden. He was successfully treated by percutaneous coronary intervention. The patient did not present any further complications during his hospital stay and was transferred to a cardiac rehabilitation centre.
    Discussion: Dual stent thrombosis is an exceptional event highlighting the high procoagulant state promoted by coronavirus 19. This case suggests that strengthening of antithrombotic therapy in CAD patients presenting with COVID-19 should be discussed.
    Language English
    Publishing date 2021-06-07
    Publishing country England
    Document type Case Reports
    ISSN 2514-2119
    ISSN (online) 2514-2119
    DOI 10.1093/ehjcr/ytab114
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Relationship between echocardiographic characteristics and cardiac biomarkers during long-distance trail running.

    Jouffroy, Romain / Hergault, Hélène / Antero, Juliana / Vieillard Baron, Antoine / Mansencal, Nicolas

    Frontiers in cardiovascular medicine

    2022  Volume 9, Page(s) 954032

    Abstract: Background: Even if the beneficial cardiovascular effects of moderate exercise are recognized, effects of prolonged and intense exercise are still debated. This study aims to detect cardiovascular changes associated with long endurance running by ... ...

    Abstract Background: Even if the beneficial cardiovascular effects of moderate exercise are recognized, effects of prolonged and intense exercise are still debated. This study aims to detect cardiovascular changes associated with long endurance running by assessing the relationship between echocardiographic parameters and cardiac biomarkers during long-distance trail running.
    Methods: We performed a prospective observational study that included 20 participants who were all amateur runners (median age of 41 years old, still alive after a 7-year clinical follow-up) from 80-km trail running. All the participants underwent an echocardiographic examination and venous blood sampling before the race, at the intermediate refreshment checkpoints of the race (21st and 53rd km), and within 10 min after arrival.
    Results: Mitral E/A velocity ratio and mitral TDI e' wave were significantly decreased at the 21st km to arrival (
    Conclusion: During the long-distance trail running, the early LV decrease in diastolic echocardiographic parameters is associated with increase in NT pro-BNP blood levels, and the decrease in LV systolic echocardiographic parameters later is associated with increase in T-troponin blood levels.
    Language English
    Publishing date 2022-08-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2022.954032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Relationship between Exercise Intensity and IL-6 Increase during an 80 km Long-Distance Running Race.

    Jouffroy, Romain / Anglicheau, Dany / Mansencal, Nicolas / Toussaint, Jean François / Antero, Juliana

    International journal of environmental research and public health

    2022  Volume 19, Issue 11

    Abstract: ... ...

    Abstract Background
    MeSH term(s) Exercise ; Humans ; Interleukin-6/blood ; Male
    Chemical Substances IL6 protein, human ; Interleukin-6
    Language English
    Publishing date 2022-05-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19116368
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  9. Article ; Online: Acute kidney injury during an ultra-distance race.

    Jouffroy, Romain / Lebreton, Xavier / Mansencal, Nicolas / Anglicheau, Dany

    PloS one

    2019  Volume 14, Issue 9, Page(s) e0222544

    Abstract: Purpose: Previous studies have noted consequences of ultra-distance trail running on health, but few studies are available regarding the temporal variations of renal biomarker injury during the running. The aim of this study was to assess the of kidney ... ...

    Abstract Purpose: Previous studies have noted consequences of ultra-distance trail running on health, but few studies are available regarding the temporal variations of renal biomarker injury during the running. The aim of this study was to assess the of kidney function parameters temporal variation during and on short-term after an ultra-distance race.
    Methods: We performed an observational study with 47 subjects participating in an ultra-distance race (80 km). Urine (47 subjects) and blood (21 subjects) samples were serially collected before (baseline-km 0), during (21 and 53 km), on arrival (80 km), and 9 days after the race (d9).
    Results: Mean serum creatinine increased during the race from 90±14 μmol/L (km0) to 136±32 μmol/L (km 80-p<0.0001) corresponding to a 52% increase. Mean creatininuria progressively increased from 4.7±4.5 mmol/L (km 0) to 22.8±12.0 mmol/L (km 80) (p<0.0001). Both urinary biomarkers (Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1) of acute kidney injury (AKI) progressively increased during the race (p<0.05 vs baseline). However, after adjustment to urine dilution by urine creatinine, no significant changes remained (p>0.05). On day 9, no significant difference remains in blood and urine biomarkers compared to their respective baseline levels.
    Conclusions: During an ultra-distance race, despite an acute and transient increase in the serum creatinine levels, urinary biomarkers of AKI displayed only limited changes with a complete regression on day 9. These results suggest the absence of the short-term impact of an ultra-distance race kidney function.
    MeSH term(s) Acute Kidney Injury/etiology ; Adult ; Biomarkers/blood ; Biomarkers/urine ; Creatinine/blood ; Creatinine/urine ; Humans ; Male ; Running/physiology
    Chemical Substances Biomarkers ; Creatinine (AYI8EX34EU)
    Language English
    Publishing date 2019-09-25
    Publishing country United States
    Document type Journal Article ; Observational Study
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0222544
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  10. Article ; Online: Prevalence and Prognostic Impact of Drug Use in Patients Hospitalized for Acute Heart Failure.

    Fauvel, Charles / Dillinger, Jean-Guillaume / Bochaton, Thomas / Mansencal, Nicolas / Noirclerc, Nathalie / Schurtz, Guillaume / Pommier, Thibaut / Laissac, Quentin / Henry, Patrick / Pezel, Théo

    JACC. Heart failure

    2024  

    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Letter
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2023.12.010
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