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Article: Dementia & Neuropsychologia: one year on.

Mansur, Letícia Lessa

Dementia & neuropsychologia

2017 Volume 2, Issue 1, Page(s) 1

Language	English
Publishing date	2017-08-22
Publishing country	Brazil
Document type	Editorial
ISSN	1980-5764
ISSN	1980-5764
DOI	10.1590/S1980-57642009DN20100001
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Knowledge of semantic categories in normal aged: Influence of education.

Barea, Karla Shimura / Mansur, Leticia Lessa

Dementia & neuropsychologia

2017 Volume 1, Issue 2, Page(s) 166–172

Abstract: Semantic memory seems to resist the effects of time, remaining stable even in more advanced ages.: Objective: To verify the effect of schooling level on semantic knowledge (non-living items) in normal aged.: Method: 48 aged individuals were divided ...

Abstract	Semantic memory seems to resist the effects of time, remaining stable even in more advanced ages. Objective: To verify the effect of schooling level on semantic knowledge (non-living items) in normal aged. Method: 48 aged individuals were divided into three groups (based on schooling) and evaluated. Three tests were applied: verbal fluency, naming and figure classification. Results: We verified that the group with greater schooling (>8 years) differed to the illiterate and low schooling groups in most of the tasks, evoking more items in verbal fluency, correctly naming more items and presenting a greater number of "formal categories". Discussion: In the verbal fluency test, this difference could be explained by the types of strategies used by the individuals to recall words. In relation to the naming test, the effect could be attributed to limitation in the vocabulary and cognitive processing skills needed to search for semantic attributes of the figures. In categorization, this type of classification is dependent on scholastic learning. Conclusion: We concluded that both illiterate elderly and those having a low schooling level, presented poorer performance in semantic memory tests compared to the aged with a higher level of schooling. The similar behavior evidenced between illiterate and low schooling groups is intriguing. It remains unclear whether the low schooling group behaved like the illiterates or vice-a-versa. This unanswered question remains the subject of future studies.
Language	English
Publishing date	2017-08-22
Publishing country	Brazil
Document type	Journal Article
ISSN	1980-5764
ISSN	1980-5764
DOI	10.1590/s1980-57642008dn10200009
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Verbal fluency: Effect of time on item generation.

Venegas, Mayra Jacuviske / Mansur, Leticia Lessa

Dementia & neuropsychologia

2017 Volume 5, Issue 2, Page(s) 104–107

Abstract: The distribution of item generation/time in the performance of elderly on verbal fluency (VF) remains unknown.: Objective: To analyze the number of items, their distribution and impact of the first quartile on the final test result.: Methods: 31 ... ...

Abstract	The distribution of item generation/time in the performance of elderly on verbal fluency (VF) remains unknown. Objective: To analyze the number of items, their distribution and impact of the first quartile on the final test result. Methods: 31 individuals performed the tests (average age=74 years; schooling=8.16 years). Results: The number of items produced in the first quartile differed from the other quartiles for both semantic and phonologic VF where 40% of items were produced in the first quartile. No effect of age was found and schooling influenced performance on the first and second quartiles of semantic VF and on the 1 Discussion: This study contributes with the finding that asymptotic levels are attained prior to the 30 seconds observed in other studies, being reached at the 15-second mark. Furthermore, schooling was found to be associated to the number of items produced in both the first and 2 Conclusion: The schooling effect was noted both in semantic and executive aspects of VF. The brief form of the VF test may represent a promising tool for clinical evaluation.
Language	English
Publishing date	2017-08-22
Publishing country	Brazil
Document type	Journal Article
ISSN	1980-5764
ISSN	1980-5764
DOI	10.1590/S1980-57642011DN05020008
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Article: Comprehension and storage of sequentially presented radio news items by healthy elderly.

Bonini, Milena Vaz / Mansur, Letícia Lessa

Dementia & neuropsychologia

2017 Volume 3, Issue 2, Page(s) 118–123

Abstract: In the normal aging processes, complaints of memory loss and auditory comprehension are not uncommon, principally in complex and cognitively demanding situations.: Objective: The objective of this study was to investigate skills of discourse ... ...

Abstract	In the normal aging processes, complaints of memory loss and auditory comprehension are not uncommon, principally in complex and cognitively demanding situations. Objective: The objective of this study was to investigate skills of discourse comprehension and retention in a natural situation, by healthy aged in relation to variables such as age, schooling and cognitive screening measurement. Methods: Thirty healthy elderly participated in the study (mean age=73.56 yrs; SD=6.26 and mean schooling=8.6 yrs; SD=4.41). Twelve news items were recorded and presented in three sequences of four news-groups. Participants were instructed to listen to the four news items, and upon completion were questioned about one of them. Results: We found no age or schooling effect on the performance of the subjects. The participants achieved almost full scores on all answers (ceiling effect). Discussion: The heterogeneity of elderly and cognitive compensation in natural situations could explain these results of elderly behavior.
Language	English
Publishing date	2017-08-22
Publishing country	Brazil
Document type	News
ISSN	1980-5764
ISSN	1980-5764
DOI	10.1590/S1980-57642009DN30200009
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Article: Analysis of prototypical narratives produced by aphasic individuals and cognitively healthy subjects.

Silveira, Gabriela / Mansur, Letícia Lessa

Dementia & neuropsychologia

2017 Volume 9, Issue 3, Page(s) 279–284

Abstract: Aphasia can globally or selectively affect comprehension and production of verbal and written language. Discourse analysis can aid language assessment and diagnosis.: Objective: [1] To explore narratives that produce a number of valid indicators for ... ...

Abstract	Aphasia can globally or selectively affect comprehension and production of verbal and written language. Discourse analysis can aid language assessment and diagnosis. Objective: [1] To explore narratives that produce a number of valid indicators for diagnosing aphasia in speakers of Brazilian Portuguese.[2] To analyze the macrostructural aspects of the discourse of normal individuals.[3] To analyze the macrostructural aspects of the discourse of aphasic individuals. Methods: The macrostructural aspects of three narratives produced by aphasic individuals and cognitively healthy subjects were analyzed. Results: A total of 30 volunteers were examined comprising 10 aphasic individuals (AG) and 20 healthy controls (CG). The CG included 5 males. The CG had a mean age of 38.9 years (SD=15.61) and mean schooling of 13 years (SD=2.67) whereas the AG had a mean age of 51.7 years (SD=17.3) and mean schooling of 9.1 years (SD=3.69). Participants were asked to narrate three fairy tales as a basis for analyzing the macrostructure of discourse. Comparison of the three narratives revealed no statistically significant difference in number of propositions produced by the groups. A significant negative correlation was found between age and number of propositions produced. Also, statistically significant differences were observed in the number of propositions produced by the individuals in the CG and the AG for the three tales. Conclusion: It was concluded that the three tales are applicable for discourse assessment, containing a similar number of propositions and differentiating aphasic individuals and cognitively healthy subjects based on analysis of the macrostructure of discourse.
Language	English
Publishing date	2017-08-22
Publishing country	Brazil
Document type	Journal Article
ISSN	1980-5764
ISSN	1980-5764
DOI	10.1590/1980-57642015DN93000011
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Article: N-Back auditory test performancein normal individuals.

Gonçalves, Vanessa Tomé / Mansur, Letícia Lessa

Dementia & neuropsychologia

2017 Volume 3, Issue 2, Page(s) 114–117

Abstract: The working memory construct refers to the capacity to maintain information for a limited time.: Objectives: To devise stimuli and adapt the 5-back test and to verify the effect of age in normal Brazilian individuals.: Methods: 31 healthy adults ( ... ...

Abstract	The working memory construct refers to the capacity to maintain information for a limited time. Objectives: To devise stimuli and adapt the 5-back test and to verify the effect of age in normal Brazilian individuals. Methods: 31 healthy adults (15 young adults and 16 older adults) were evaluated by batteries of auditory stimuli to verify the inter-group differences (age effect) in working memory span, total correct answers and intrusions, and the intra-group effect of type of stimulus. Results: There was no intra-group stimulus effect. Individuals from both groups processed di and tri-syllables similarly. No difference between groups (no age effect) was observed for any N-Back parameters: total score, span, number of intrusions, in either di or tri-syllable presentation. Conclusion: the processing capacity of 5 elements in phonological working memory was not affected by age.
Language	English
Publishing date	2017-08-22
Publishing country	Brazil
Document type	Journal Article
ISSN	1980-5764
ISSN	1980-5764
DOI	10.1590/S1980-57642009DN30200008
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Article ; Online: Aphasia in vascular lesions of the basal ganglia: A comprehensive review.

Radanovic, Marcia / Mansur, Leticia Lessa

Brain and language

2017 Volume 173, Page(s) 20–32

Abstract: Between 1970 and 1990, the study of aphasia secondary to subcortical lesions (including the basal ganglia - BG) was largely driven by the advent of modern neuroimaging techniques such as MRI and PET. However, attempts to characterize a pattern of ... ...

Abstract	Between 1970 and 1990, the study of aphasia secondary to subcortical lesions (including the basal ganglia - BG) was largely driven by the advent of modern neuroimaging techniques such as MRI and PET. However, attempts to characterize a pattern of language abnormalities in patients with basal ganglia lesions proved unfruitful. We conducted a comprehensive review of language disturbances after vascular lesions in the BG. Literature search in Medline and LILACS (1966-2016) and PsychINFO (last 25years) was conducted, and returned 145 articles, with 57 eligible for the review yielding data on 303 patients. We report the clinical and neuroimaging features of these cases. Results showed that aphasias caused by BG lesions are heterogeneous with weak clinicoanatomical correlations. Data derived from follow-up and flow/metabolism studies suggest that subcortical aphasia caused by BG lesions involves hypoperfusion in the cortical territories of the middle cerebral/internal carotid arteries (MCA/ICA) and their branches.
MeSH term(s)	Aphasia/pathology ; Basal Ganglia/pathology ; Humans ; Language ; Magnetic Resonance Imaging ; Neuroimaging
Language	English
Publishing date	2017-10
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	7448-2
ISSN	1090-2155 ; 0093-934X
ISSN (online)	1090-2155
ISSN	0093-934X
DOI	10.1016/j.bandl.2017.05.003
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Article ; Online: Oral dyspraxia in self-limited epilepsy with centrotemporal spikes: a comparative study with a control group.

Bernardo, Henrique Nicola Santo Antonio / Miziara, Carmen Sílvia Molleis Galego / Manreza, Maria Luiza Giraldes de / Mansur, Letícia Lessa

Arquivos de neuro-psiquiatria

2021 Volume 79, Issue 12, Page(s) 1076–1083

Abstract: Background: self-limited epilepsy with centrotemporal spikes, previously considered benign focal childhood epilepsy with centrotemporal spikes show clinical signs of involvement of Rolandic areas, mainly lower area, which may affect the planning and ... ...

Abstract	Background: self-limited epilepsy with centrotemporal spikes, previously considered benign focal childhood epilepsy with centrotemporal spikes show clinical signs of involvement of Rolandic areas, mainly lower area, which may affect the planning and execution of motor sequences. Objective: This study aimed to evaluated oral praxis in children with self-limited epilepsy with centrotemporal spikes and compare to the age-matched control group. Methods: This was a descriptive study with 74 children with self-limited epilepsy with centrotemporal spikes, with the classical forms according to International League Against Epilepsy, and between 4 and 15 years of age, selected from the child neurology outpatient clinic of the Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, and 239 age-matched and educational level-matched (convenience sampling) control children. All children were submitted to the battery of oral volitional movements, which consisted of 44 tests for oral movement (tongue, lip, cheek, jaw, and palate) and 34 phonemes and consonant cluster tasks, with simple and sequenced oral movements. Results: The mean age and standard deviation (SD) of children with epilepsy was 9.08 years (SD 2.55) and of controls 9.61 years (SD 3.12). The results showed significant differences between the groups with a poorer performance of children with epilepsy compared to children without epilepsy in simple and particularly in sequenced movements. Conclusion: These findings can be attributed to the genetically determined immaturity of cortical structures related to motor planning in children with self-limited epilepsy with centrotemporal spikes.
MeSH term(s)	Apraxias ; Brazil ; Child ; Control Groups ; Electroencephalography ; Epilepsy, Rolandic ; Humans
Language	English
Publishing date	2021-12-22
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	418916-4
ISSN	1678-4227 ; 0004-282X
ISSN (online)	1678-4227
ISSN	0004-282X
DOI	10.1590/0004-282X-ANP-2021-0056
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Article ; Online: Swallowing in behavioral variant frontotemporal dementia.

Marin, Sheilla de Medeiros Correia / Mansur, Letícia Lessa / Oliveira, Fabricio Ferreira de / Marin, Luis Fabiano / Wajman, José Roberto / Bahia, Valéria Santoro / Bertolucci, Paulo Henrique Ferreira

Arquivos de neuro-psiquiatria

2021 Volume 79, Issue 1, Page(s) 8–14

Abstract: Background: Swallowing and feeding problems may occur with the progression of behavioral variant frontotemporal dementia (bvFTD) and can impair the anticipatory and oral preparatory phases of swallowing.: Objective: To characterize swallowing ... ...

Abstract	Background: Swallowing and feeding problems may occur with the progression of behavioral variant frontotemporal dementia (bvFTD) and can impair the anticipatory and oral preparatory phases of swallowing. Objective: To characterize swallowing problems and the feeding situation of patients with bvFTD and to correlate the swallowing problems with functionality, executive functions, cognitive and behavioral features. Methods: Consecutive outpatients with bvFTD in mild, moderate and severe dementia stages were recruited along with their caregivers. Patients and caregivers were screened with the following scales: "Mini-Mental State Examination", "Severe Mini-Mental State Examination", "FTLD-modified Clinical Dementia Rating", "Neuropsychiatric Inventory", "Frontal Assessment Battery", "Index of Independence in Activities of Daily Living", "Swallowing Rating Scale" and "Assessment of Feeding and Swallowing Difficulties in Dementia". Results: Overall, thirty patients with bvFTD were included along with their caregivers. Patients with bvFTD showed feeding and swallowing difficulties such as: messy to eat, passivity, coughing and choking, difficulty with some food consistencies and with specific food. Swallowing problems in bvFTD correlated with impaired functionality (p<0.05) and cognition (p<0.05), executive dysfunction (p<0.01) and behavioral features (p<0.01). Caregivers had great difficulty in managing the feeding situation during mealtime, with different characteristics in each dementia stage. Conclusion: Patients with bvFTD had inappropriate speed eating, passivity, coughing and choking starting in the mild dementia stage, and these problems worsen in the severe stage. Such difficulties affected caregiver performance during mealtime. The correlations indicated that swallowing difficulties tend to follow cognitive and behavioral decline in patients with bvFTD.
MeSH term(s)	Activities of Daily Living ; Alzheimer Disease ; Cognitive Dysfunction ; Deglutition ; Frontotemporal Dementia ; Humans ; Neuropsychological Tests
Language	English
Publishing date	2021-03-22
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	418916-4
ISSN	1678-4227 ; 0004-282X
ISSN (online)	1678-4227
ISSN	0004-282X
DOI	10.1590/0004-282X20200060
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Article: Oral dyspraxia in self-limited epilepsy with centrotemporal spikes: a comparative study with a control group

BERNARDO, Henrique Nicola Santo Antonio / MIZIARA, Carmen Sílvia Molleis Galego / MANREZA, Maria Luiza Giraldes de / MANSUR, Letícia Lessa

Arquivos de Neuro-Psiquiatria

2021 Volume 79, Issue 12, Page(s) 1076–1083

Abstract	Background: self-limited epilepsy with centrotemporal spikes, previously considered benign focal childhood epilepsy with centrotemporal spikes show clinical signs of involvement of Rolandic areas, mainly lower area, which may affect the planning and execution of motor sequences. Objective: This study aimed to evaluated oral praxis in children with self-limited epilepsy with centrotemporal spikes and compare to the age-matched control group. Methods: This was a descriptive study with 74 children with self-limited epilepsy with centrotemporal spikes, with the classical forms according to International League Against Epilepsy, and between 4 and 15 years of age, selected from the child neurology outpatient clinic of the Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, and 239 age-matched and educational level-matched (convenience sampling) control children. All children were submitted to the battery of oral volitional movements, which consisted of 44 tests for oral movement (tongue, lip, cheek, jaw, and palate) and 34 phonemes and consonant cluster tasks, with simple and sequenced oral movements. Results: The mean age and standard deviation (SD) of children with epilepsy was 9.08 years (SD 2.55) and of controls 9.61 years (SD 3.12). The results showed significant differences between the groups with a poorer performance of children with epilepsy compared to children without epilepsy in simple and particularly in sequenced movements. Conclusion: These findings can be attributed to the genetically determined immaturity of cortical structures related to motor planning in children with self-limited epilepsy with centrotemporal spikes.
Keywords	Epilepsy ; Epilepsy, Rolandic ; Apraxias ; Epilepsia ; Epilepsia Rolândica ; Apraxias
Language	English
Publishing date	2021-12-01
Publisher	Thieme Revinter Publicações Ltda.
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	418916-4
ISSN	1678-4227 ; 0004-282X
ISSN (online)	1678-4227
ISSN	0004-282X
DOI	10.1590/0004-282X-ANP-2021-0056
Database	Thieme publisher's database

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