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Article ; Online: Effect of insertion site on tunnelled haemodialysis catheter outcomes: an observational study of 967 catheters.

Yaxley, Julian / Gately, Ryan / Scott, Tahira / Kurtkoti, Jagadeesh / Mantha, Murty

2023 Volume 54, Issue 4, Page(s) 632–638

Abstract: Background: The right internal jugular vein is the preferred approach to tunnelled haemodialysis catheter placement. However, the effect of the insertion site on long-term catheter outcomes remains uncertain.: Aims: We aimed to analyse a large cohort ...

Abstract	Background: The right internal jugular vein is the preferred approach to tunnelled haemodialysis catheter placement. However, the effect of the insertion site on long-term catheter outcomes remains uncertain. Aims: We aimed to analyse a large cohort of tunnelled haemodialysis catheter placements to compare short-term and long-term results according to central venous catheter location. Methods: A retrospective cohort study was performed on consecutive tunnelled catheter insertions at two centres over 7 years. The primary outcome was catheter survival, compared according to the central vein site. We used the Kaplan-Meier curve method and Cox proportional hazards modelling to determine the effect of the catheterisation route on primary patency, adjusted for clinical risk factors for catheter failure. Results: There were 967 tunnelled dialysis catheter placements in 620 patients. The median survival for right internal jugular vein catheters was 569 days. There were no differences in rates of catheter failure between right internal jugular, left internal jugular (adjusted hazard ratio [HR], 0.80; 95% confidence interval [CI], 0.52-1.21), external jugular (HR, 0.79; CI, 0.33-3.13), subclavian (HR, 0.67; CI, 0.58-2.44) and femoral vein (HR, 1.20; CI, 0.36-1.33) catheters following multivariable analysis. There were no major differences in functionality or complications between the groups. Conclusions: This study identified no statistically significant relationship between tunnelled haemodialysis catheter insertion site and catheter survival. The contemporary approach to dialysis vascular access should be tailored to specific patient circumstances.
MeSH term(s)	Humans ; Catheters, Indwelling/adverse effects ; Retrospective Studies ; Catheterization ; Central Venous Catheters ; Jugular Veins ; Renal Dialysis/adverse effects ; Catheterization, Central Venous/adverse effects
Language	English
Publishing date	2023-08-18
Publishing country	Australia
Document type	Observational Study ; Journal Article
ZDB-ID	2045436-3
ISSN	1445-5994 ; 1444-0903
ISSN (online)	1445-5994
ISSN	1444-0903
DOI	10.1111/imj.16200
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Zs.A 792: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 424: Show issues

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Article ; Online: Interventional nephrology in Australia and New Zealand.

Yaxley, Julian / Palamuthusingam, Dharmenaan / Burke, Michael / Mantha, Murty

The journal of vascular access

2022 Volume 24, Issue 6, Page(s) 1538–1539

MeSH term(s)	Humans ; Nephrology ; New Zealand ; Health Care Surveys ; Australia
Language	English
Publishing date	2022-02-09
Publishing country	United States
Document type	Letter
ZDB-ID	2252820-9
ISSN	1724-6032 ; 1129-7298
ISSN (online)	1724-6032
ISSN	1129-7298
DOI	10.1177/11297298221077776
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Article ; Online: Low Posterior Internal Jugular Vein Approach for Tunnelled Haemodialysis Catheter Insertion: A Report on Outcomes at a Single Centre.

Yaxley, Julian / Gately, Ryan / Davidson-West, Shaun / Wilkinson, Catherine / Mantha, Murty

Vascular and endovascular surgery

2023 Volume 58, Issue 2, Page(s) 136–141

Abstract: Aim: The impact of technical differences in cannulation technique for tunnelled haemodialysis catheter insertion is undetermined. We aimed to assess clinical outcomes of the low posterior approach for internal jugular vein tunnelled catheter placement.!# ...

Abstract	Aim: The impact of technical differences in cannulation technique for tunnelled haemodialysis catheter insertion is undetermined. We aimed to assess clinical outcomes of the low posterior approach for internal jugular vein tunnelled catheter placement. Methods: A retrospective audit was undertaken on consecutive tunnelled catheter procedures performed at a single centre between January 2016 and June 2022. Only catheters specifically placed with a low posterior internal jugular approach were included. The study's primary outcome was 12-month catheter survival, evaluated using the Kaplan-Meier survival curve and log-rank test. Secondary outcomes included catheter performance and procedure-related complications. Results: During the study period, 391 tunnelled internal jugular haemodialysis catheters were inserted in 272 patients using the low posterior technique. The 12-month primary patency rate was 68%. Catheter insertion was successful in 96% of cases. Peri-procedural complications occurred in 4% of cases, most frequently bleeding. The most common reasons for catheter loss were dysfunction (10%) and bacteraemia (6%). The best predictors of catheter failure were advanced age (HR 1.02, 95% CI 1.00-1.04) and in-centre dialysis treatment locality (HR 2.04, 95% CI 1.19-3.45). Conclusion: The low posterior approach for internal jugular vein tunnelled catheter insertion is effective and safe. We demonstrated a 12-month catheter survival rate of 68%. Further research comparing the low posterior approach with other internal jugular vein cannulation techniques is warranted.
MeSH term(s)	Humans ; Catheters, Indwelling ; Retrospective Studies ; Jugular Veins/diagnostic imaging ; Treatment Outcome ; Catheterization, Central Venous/adverse effects ; Renal Dialysis
Language	English
Publishing date	2023-08-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	2076272-0
ISSN	1938-9116 ; 1538-5744
ISSN (online)	1938-9116
ISSN	1538-5744
DOI	10.1177/15385744231196651
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Zs.A 622: Show issues

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Article ; Online: Clavicular hook: Cuffed haemodialysis catheter insertion using a paramedian tunnel in patients with recurrent tip migration.

Yaxley, Julian / Wilkinson, Catherine / Davidson-West, Shaun / Mantha, Murty

The journal of vascular access

2022 Volume 25, Issue 2, Page(s) 669–672

Abstract: Tunnelled, cuffed central venous catheters are commonly used for the provision of haemodialysis. Internal jugular vein catheters are generally tunnelled subcutaneously to the anterolateral chest wall. However, the lateral subcutaneous tract may increase ... ...

Abstract	Tunnelled, cuffed central venous catheters are commonly used for the provision of haemodialysis. Internal jugular vein catheters are generally tunnelled subcutaneously to the anterolateral chest wall. However, the lateral subcutaneous tract may increase the risk of catheter migration, particularly in the setting of obesity or large breast tissue. Catheter tip migration is an important cause of catheter failure. We describe two cases in which a paramedian tunnel was fashioned in patients experiencing recurrent catheter migration.
MeSH term(s)	Humans ; Catheterization, Central Venous ; Catheters, Indwelling ; Equipment Design ; Renal Dialysis ; Central Venous Catheters ; Jugular Veins
Language	English
Publishing date	2022-11-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	2252820-9
ISSN	1724-6032 ; 1129-7298
ISSN (online)	1724-6032
ISSN	1129-7298
DOI	10.1177/11297298221138334
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Zs.A 6414: Show issues

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Article ; Online: Lessons for the clinical nephrologist: dialysis decisions in early pregnancy for acute kidney injury due to post-infectious glomerulonephritis (PIGN).

De Souza, Laura / Ismail, Ibrahim / Baade, Robert / Mantha, Murty

Journal of nephrology

2022 Volume 35, Issue 9, Page(s) 2399–2401

MeSH term(s)	Humans ; Pregnancy ; Female ; Nephrologists ; Renal Dialysis/adverse effects ; Glomerulonephritis/diagnosis ; Glomerulonephritis/therapy ; Acute Kidney Injury/diagnosis ; Acute Kidney Injury/etiology ; Acute Kidney Injury/therapy
Language	English
Publishing date	2022-10-14
Publishing country	Italy
Document type	Journal Article
ZDB-ID	1093991-x
ISSN	1724-6059 ; 1120-3625 ; 1121-8428
ISSN (online)	1724-6059
ISSN	1120-3625 ; 1121-8428
DOI	10.1007/s40620-022-01464-0
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Zs.A 3369: Show issues

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Article ; Online: Azathioprine hypersensitivity syndrome: report of two cases.

McKenzie, Tahlia / Dheda, Shyam / Mantha, Murty / Larsen, Catherine

BMJ case reports

2021 Volume 14, Issue 5

Abstract: Azathioprine hypersensitivity syndrome is a rare but potentially severe side effect of azathioprine use. It has a variable and non-specific presentation making it difficult to distinguish from sepsis or disease relapse. High clinical suspicion is ... ...

Abstract	Azathioprine hypersensitivity syndrome is a rare but potentially severe side effect of azathioprine use. It has a variable and non-specific presentation making it difficult to distinguish from sepsis or disease relapse. High clinical suspicion is therefore required for recognition and prompt cessation of azathioprine for symptom resolution. Herewith two cases of severe azathioprine hypersensitivity syndrome are described, one in association with Sweet syndrome. Both presented with vague symptoms 2 weeks after commencing azathioprine for antineutrophil cytoplasmic antibody vasculitis. The differentials of sepsis and disease relapse were considered prior to cessation of azathioprine which resulted in a dramatic improvement in both cases. These cases highlight the diagnostic challenge azathioprine hypersensitivity syndrome presents. It should be suspected when there is a temporal relationship to drug initiation, with absence of infection or serological evidence of disease relapse.
MeSH term(s)	Antibodies, Antineutrophil Cytoplasmic ; Azathioprine/adverse effects ; Drug Hypersensitivity/diagnosis ; Drug Hypersensitivity/etiology ; Drug Hypersensitivity Syndrome ; Humans ; Immunosuppressive Agents/adverse effects ; Sweet Syndrome/chemically induced ; Sweet Syndrome/diagnosis ; Sweet Syndrome/drug therapy
Chemical Substances	Antibodies, Antineutrophil Cytoplasmic ; Immunosuppressive Agents ; Azathioprine (MRK240IY2L)
Language	English
Publishing date	2021-05-19
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1757-790X
ISSN (online)	1757-790X
DOI	10.1136/bcr-2020-239099
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Article ; Online: HMG CoA reductase inhibitor associated myositis and autoimmune hepatitis.

Palamuthusingam, Dharmenaan / Mantha, Murty / Dheda, Shyam

Internal medicine journal

2017 Volume 47, Issue 10, Page(s) 1213–1215

MeSH term(s)	Aged ; Anti-Inflammatory Agents/therapeutic use ; Azathioprine/therapeutic use ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/physiopathology ; Fatal Outcome ; Female ; Hepatitis, Autoimmune/drug therapy ; Hepatitis, Autoimmune/etiology ; Hepatitis, Autoimmune/physiopathology ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects ; Myositis/diagnostic imaging ; Myositis/drug therapy ; Myositis/etiology ; Prednisolone/therapeutic use ; Renal Insufficiency, Chronic/drug therapy ; Renal Insufficiency, Chronic/physiopathology
Chemical Substances	Anti-Inflammatory Agents ; Hydroxymethylglutaryl-CoA Reductase Inhibitors ; Prednisolone (9PHQ9Y1OLM) ; Azathioprine (MRK240IY2L)
Language	English
Publishing date	2017-10-06
Publishing country	Australia
Document type	Case Reports ; Letter
ZDB-ID	2045436-3
ISSN	1445-5994 ; 1444-0903
ISSN (online)	1445-5994
ISSN	1444-0903
DOI	10.1111/imj.13561
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Zs.A 792: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Lupus nephritis in Indigenous Australians: a single-centre study.

Nigam, Amit / Baer, Richard / Green, Stella / Neuen, Brendon L / Vile, Alexander / Mantha, Murty

Internal medicine journal

2019 Volume 50, Issue 7, Page(s) 830–837

Abstract: Background: The incidence, presentation and outcomes of lupus nephritis (LN) vary with geography, ethnicity, socioeconomic status and gender. There are relatively few data on LN in the non-Caucasian populations in Australia.: Aims: To describe the ... ...

Abstract	Background: The incidence, presentation and outcomes of lupus nephritis (LN) vary with geography, ethnicity, socioeconomic status and gender. There are relatively few data on LN in the non-Caucasian populations in Australia. Aims: To describe the clinical presentation, histological features, natural history, and outcomes of a historical cohort of Aboriginal and Torres Strait Islanders people in Far North Queensland with biopsy-proven LN. Methods: This is a retrospective observational study, and the study was conducted in Cairns and Hinterland Hospital and Health Service, Queensland, Australia. The study included Aboriginal and Torres Strait Islander patients with biopsy-proven LN treated between 1990 and 2013. The main outcome measures were renal replacement therapy and overall patient survival. Results: Aboriginal and Torres Strait Islander people represented a substantial proportion (n = 16/40, 40%) of all patients diagnosed with LN during the observation period. The frequency of nephrotic range proteinuria (n = 11/14, 78.5%), estimated glomerular filtration rate <60 mL/min/1.73 m Conclusions: The clinical presentation of LN in Aboriginal and Torres Strait Islanders in Far North Queensland is severe and the response to standard immunosuppressive therapy is unsatisfactory. Larger prospective multi-centre studies are required to better understand ethnic disparities in prognosis and response to immunosuppressive therapy in this specific population.
MeSH term(s)	Australia/epidemiology ; Health Services, Indigenous ; Humans ; Lupus Nephritis/diagnosis ; Lupus Nephritis/drug therapy ; Lupus Nephritis/epidemiology ; Oceanic Ancestry Group ; Prospective Studies ; Queensland/epidemiology
Language	English
Publishing date	2019-11-09
Publishing country	Australia
Document type	Journal Article ; Observational Study
ZDB-ID	2045436-3
ISSN	1445-5994 ; 1444-0903
ISSN (online)	1445-5994
ISSN	1444-0903
DOI	10.1111/imj.14710
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Zs.A 792: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Mini review: A unique case of crescentic C3 glomerulonephritis.

Palamuthusingam, Dharmenaan / Mantha, Murty / Oliver, Kimberley / Bavishi, Ketan / Dheda, Shyam

Nephrology (Carlton, Vic.)

2017 Volume 22, Issue 3, Page(s) 261–264

Abstract: Kidney involvement is an under-recognized complication of non-Hodgkin lymphomas. They occur in a variety of mechanisms and differ widely in their clinical presentation. We take this opportunity to report a case of a 65 year-old man who developed a ... ...

Abstract	Kidney involvement is an under-recognized complication of non-Hodgkin lymphomas. They occur in a variety of mechanisms and differ widely in their clinical presentation. We take this opportunity to report a case of a 65 year-old man who developed a rapidly progressive glomerulonephritis within days after completing his first cycle of R-CHOP (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, Prednisolone) chemotherapy for newly diagnosed mantle cell lymphoma. He was odematous, hypertensive, oliguric with nephrotic range proteinuria and an active urine sediment. A renal biopsy showed a crescentic C3 glomerulonephritis (C3GN) with no evidence endocapillary or mesangial hypercellularity. He was promptly treated with immunosuppression and dialysis, with resumption of his chemotherapy. Genetic testing on complement proteins revealed a homozygous deletion spanning the CFHR1 and CFHR3 genes. Crescentic C3GN is a rare form of kidney injury, and this is the first known case of lymphoma-associated kidney involvement manifesting as C3GN. This article explores the possible mechanism of disease and reviews the literature of lymphoma-related kidney disease.
MeSH term(s)	Aged ; Glomerulonephritis, Membranoproliferative/diagnosis ; Glomerulonephritis, Membranoproliferative/etiology ; Humans ; Lymphoma, Mantle-Cell/complications ; Lymphoma, Mantle-Cell/drug therapy ; Lymphoma, Mantle-Cell/pathology ; Male
Language	English
Publishing date	2017-03
Publishing country	Australia
Document type	Case Reports ; Journal Article
ZDB-ID	1303661-0
ISSN	1440-1797 ; 1320-5358
ISSN (online)	1440-1797
ISSN	1320-5358
DOI	10.1111/nep.12925
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Zs.A 4822: Show issues

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Article ; Online: Solitary jejunal metastasis from renal cell carcinoma presenting as small bowel obstruction 19 years after nephrectomy.

Ismail, Ibrahim / Neuen, Brendon Lange / Mantha, Murty

BMJ case reports

2015 Volume 2015

Abstract: Metachronous metastatic disease may develop in up to 50% of patients with renal cell carcinoma (RCC) who have undergone a presumably curative radical nephrectomy. We describe a case of small bowel obstruction secondary to a solitary jejunal RCC ... ...

Abstract	Metachronous metastatic disease may develop in up to 50% of patients with renal cell carcinoma (RCC) who have undergone a presumably curative radical nephrectomy. We describe a case of small bowel obstruction secondary to a solitary jejunal RCC metastasis affecting a 66-year-old man with a history of RCC, which was treated 19 years earlier by right radical nephrectomy. The patient underwent successful laparotomy and wide margin resection of the affected small bowel with end-to-end anastomosis. A subsequent staging CT revealed no other metastases. To our knowledge, only eight cases of isolated small bowel metastasis from RCC have been reported. Of these, only one previous report referred to a longer time interval to small bowel metastasis than our case. The case highlights that isolated bowel metastasis should be considered as a possible aetiology of small bowel obstruction, even in patients with a distant history of presumably curative cancer treatment.
MeSH term(s)	Aged ; Carcinoma, Renal Cell/secondary ; Carcinoma, Renal Cell/surgery ; Humans ; Intestinal Obstruction/etiology ; Intestinal Obstruction/surgery ; Intestine, Small/surgery ; Jejunal Neoplasms/secondary ; Jejunal Neoplasms/surgery ; Kidney Neoplasms/pathology ; Kidney Neoplasms/surgery ; Male ; Nephrectomy ; Time Factors ; Treatment Outcome
Language	English
Publishing date	2015-09-14
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1757-790X
ISSN (online)	1757-790X
DOI	10.1136/bcr-2015-210857
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