LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 5 of total 5

Search options

  1. Article ; Online: In Silico Investigation of Potential Applications of Gamma Carbonic Anhydrases as Catalysts of CO

    Manyumwa, Colleen Varaidzo / Bishop, Özlem Tastan

    International journal of molecular sciences

    2021  Volume 22, Issue 6

    Abstract: Carbonic anhydrases (CAs) have been identified as ideal catalysts for ... ...

    Abstract Carbonic anhydrases (CAs) have been identified as ideal catalysts for CO
    MeSH term(s) Amino Acid Sequence ; Bacteria/enzymology ; Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Biomineralization ; Carbon Dioxide/chemistry ; Carbon Dioxide/metabolism ; Carbonic Anhydrases/chemistry ; Carbonic Anhydrases/genetics ; Carbonic Anhydrases/metabolism ; Catalysis ; Catalytic Domain ; Computer Simulation ; Hot Springs/microbiology ; Hydrothermal Vents/microbiology ; Molecular Dynamics Simulation ; Protein Conformation ; Sequence Homology, Amino Acid ; Temperature ; Thermus thermophilus/enzymology
    Chemical Substances Bacterial Proteins ; Carbon Dioxide (142M471B3J) ; Carbonic Anhydrases (EC 4.2.1.1)
    Language English
    Publishing date 2021-03-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms22062861
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Genome Study of α-, β-, and γ-Carbonic Anhydrases from the Thermophilic Microbiome of Marine Hydrothermal Vent Ecosystems

    Gheibzadeh, Mohammad Sadegh / Manyumwa, Colleen Varaidzo / Tastan Bishop, Özlem / Shahbani Zahiri, Hossein / Parkkila, Seppo / Zolfaghari Emameh, Reza

    Biology (Basel). 2023 May 25, v. 12, no. 6

    2023  

    Abstract: Carbonic anhydrases (CAs) are metalloenzymes that can help organisms survive in hydrothermal vents by hydrating carbon dioxide (CO₂). In this study, we focus on alpha (α), beta (β), and gamma (γ) CAs, which are present in the thermophilic microbiome of ... ...

    Abstract Carbonic anhydrases (CAs) are metalloenzymes that can help organisms survive in hydrothermal vents by hydrating carbon dioxide (CO₂). In this study, we focus on alpha (α), beta (β), and gamma (γ) CAs, which are present in the thermophilic microbiome of marine hydrothermal vents. The coding genes of these enzymes can be transferred between hydrothermal-vent organisms via horizontal gene transfer (HGT), which is an important tool in natural biodiversity. We performed big data mining and bioinformatics studies on α-, β-, and γ-CA coding genes from the thermophilic microbiome of marine hydrothermal vents. The results showed a reasonable association between thermostable α-, β-, and γ-CAs in the microbial population of the hydrothermal vents. This relationship could be due to HGT. We found evidence of HGT of α- and β-CAs between Cycloclasticus sp., a symbiont of Bathymodiolus heckerae, and an endosymbiont of Riftia pachyptila via Integrons. Conversely, HGT of β-CA genes from the endosymbiont Tevnia jerichonana to the endosymbiont Riftia pachyptila was detected. In addition, Hydrogenovibrio crunogenus SP-41 contains a β-CA gene on genomic islands (GIs). This gene can be transferred by HGT to Hydrogenovibrio sp. MA2-6, a methanotrophic endosymbiont of Bathymodiolus azoricus, and a methanotrophic endosymbiont of Bathymodiolus puteoserpentis. The endosymbiont of R. pachyptila has a γ-CA gene in the genome. If α- and β-CA coding genes have been derived from other microorganisms, such as endosymbionts of T. jerichonana and Cycloclasticus sp. as the endosymbiont of B. heckerae, through HGT, the theory of the necessity of thermostable CA enzymes for survival in the extreme ecosystem of hydrothermal vents is suggested and helps the conservation of microbiome natural diversity in hydrothermal vents. These harsh ecosystems, with their integral players, such as HGT and endosymbionts, significantly impact the enrichment of life on Earth and the carbon cycle in the ocean.
    Keywords Cycloclasticus ; Hydrogenovibrio ; biodiversity ; bioinformatics ; carbon cycle ; carbon dioxide ; carbonate dehydratase ; ecosystems ; endosymbionts ; genes ; genomics ; horizontal gene transfer ; methanotrophs ; microbiome ; thermal stability
    Language English
    Dates of publication 2023-0525
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology12060770
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Alpha-Carbonic Anhydrases from Hydrothermal Vent Sources as Potential Carbon Dioxide Sequestration Agents:

    Manyumwa, Colleen Varaidzo / Emameh, Reza Zolfaghari / Tastan Bishop, Özlem

    International journal of molecular sciences

    2020  Volume 21, Issue 21

    Abstract: With the increase in ... ...

    Abstract With the increase in CO
    MeSH term(s) Amino Acid Sequence ; Bacteria/enzymology ; Bacterial Proteins/metabolism ; Carbon Dioxide/isolation & purification ; Carbon Dioxide/metabolism ; Carbonic Anhydrases/chemistry ; Carbonic Anhydrases/metabolism ; Computer Simulation ; Hydrothermal Vents/microbiology ; Molecular Dynamics Simulation ; Sequence Homology ; Sequestering Agents/metabolism
    Chemical Substances Bacterial Proteins ; Sequestering Agents ; Carbon Dioxide (142M471B3J) ; Carbonic Anhydrases (EC 4.2.1.1)
    Keywords covid19
    Language English
    Publishing date 2020-10-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms21218066
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Genome Study of α-, β-, and γ-Carbonic Anhydrases from the Thermophilic Microbiome of Marine Hydrothermal Vent Ecosystems.

    Gheibzadeh, Mohammad Sadegh / Manyumwa, Colleen Varaidzo / Tastan Bishop, Özlem / Shahbani Zahiri, Hossein / Parkkila, Seppo / Zolfaghari Emameh, Reza

    Biology

    2023  Volume 12, Issue 6

    Abstract: Carbonic anhydrases (CAs) are metalloenzymes that can help organisms survive in hydrothermal vents by hydrating carbon dioxide ( ... ...

    Abstract Carbonic anhydrases (CAs) are metalloenzymes that can help organisms survive in hydrothermal vents by hydrating carbon dioxide (CO
    Language English
    Publishing date 2023-05-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology12060770
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Decoding the Molecular Effects of Atovaquone Linked Resistant Mutations on

    Chebon-Bore, Lorna / Sanyanga, Taremekedzwa Allan / Manyumwa, Colleen Varaidzo / Khairallah, Afrah / Tastan Bishop, Özlem

    International journal of molecular sciences

    2021  Volume 22, Issue 4

    Abstract: Atovaquone (ATQ) is a drug used to prevent and treat malaria that functions by targeting ... ...

    Abstract Atovaquone (ATQ) is a drug used to prevent and treat malaria that functions by targeting the
    MeSH term(s) Animals ; Atovaquone/chemistry ; Atovaquone/pharmacology ; Catalytic Domain ; Cattle ; Cytochromes b/genetics ; Drug Resistance/drug effects ; Drug Resistance/genetics ; Entropy ; Iron-Sulfur Proteins/genetics ; Iron-Sulfur Proteins/metabolism ; Ligands ; Lipid Bilayers/metabolism ; Models, Molecular ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Mutation/genetics ; Phospholipids/metabolism ; Plasmodium falciparum/drug effects ; Plasmodium falciparum/genetics ; Protein Conformation ; Protein Interaction Maps ; Protein Stability
    Chemical Substances Iron-Sulfur Proteins ; Ligands ; Lipid Bilayers ; Phospholipids ; Cytochromes b (9035-37-4) ; Atovaquone (Y883P1Z2LT)
    Language English
    Publishing date 2021-02-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms22042138
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top