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Book ; Online: Doppler-Resilient Design of CAZAC Sequences for mmWave/THz Sensing Applications

Zhang, Fan / Mao, Tianqi / Wang, Zhaocheng

2023

Abstract: Ultra-high-resolution target sensing has emerged as a key enabler for various cutting-edge applications, which can be realized by utilizing the millimeter wave/terahertz frequencies. However, the extremely high operating frequency inevitably leads to ... ...

Abstract	Ultra-high-resolution target sensing has emerged as a key enabler for various cutting-edge applications, which can be realized by utilizing the millimeter wave/terahertz frequencies. However, the extremely high operating frequency inevitably leads to significant Doppler shift effects, especially for high-mobility applications, causing the degradation of sensing performance with high false alarm rate. To this end, this paper proposes a parameter design methodology of the well-known constant amplitude zero auto correlation (CAZAC) sequences, which aims at enhancing their resilience to Doppler shifts. Specifically, we suppress the sidelobes incurred by Doppler shifts for the peak-to-sidelobe ratio (PSLR) improvement within the range of interest (RoI) of the radar range profile. The Zadoff-Chu (ZC) sequence, as a representative member in the CAZAC family, is firstly considered. The impacts of its root index on range sidelobes are investigated based on number theory. For an arbitrary-length ZC sequence, a feasible range of the root index is derived to satisfy the requirement of PSLR within the scope of RoI. Furthermore, these design guidelines are extended to a general form of CAZAC sequences, where a low-complexity heuristic algorithm is developed for PSLR improvement. Simulation results demonstrate that under severe Doppler shifts, our proposed methodology could enhance the sensing performance by lowering the false alarm rate while maintaining the same detection rate, compared with its classical counterpart.
Keywords	Electrical Engineering and Systems Science - Signal Processing
Subject code	621
Publishing date	2023-05-12
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Comprehensive insights into potential roles of purinergic P2 receptors on diseases: Signaling pathways involved and potential therapeutics.

Guo, Yanshuo / Mao, Tianqi / Fang, Yafei / Wang, Hui / Yu, Jiayue / Zhu, Yifan / Shen, Shige / Zhou, Mengze / Li, Huanqiu / Hu, Qinghua

Journal of advanced research

2024

Abstract: Background: Purinergic P2 receptors, which can be divided into ionotropic P2X receptors and metabotropic P2Y receptors, mediate cellular signal transduction of purine or pyrimidine nucleoside triphosphates and diphosphate. Based on the wide expression ... ...

Abstract	Background: Purinergic P2 receptors, which can be divided into ionotropic P2X receptors and metabotropic P2Y receptors, mediate cellular signal transduction of purine or pyrimidine nucleoside triphosphates and diphosphate. Based on the wide expression of purinergic P2 receptors in tissues and organs, their significance in homeostatic maintenance, metabolism, nociceptive transmission, and other physiological processes is becoming increasingly evident, suggesting that targeting purinergic P2 receptors to regulate biological functions and signal transmission holds significant promise for disease treatment. Aim of review: This review highlights the detailed mechanisms by which purinergic P2 receptors engage in physiological and pathological progress, as well as providing prospective strategies for discovering clinical drug candidates. Key scientific concepts of review: The purinergic P2 receptors regulate complex signaling and molecular mechanisms in nervous system, digestive system, immune system and as a result, controlling physical health states and disease progression. There has been a significant rise in research and development focused on purinergic P2 receptors, contributing to an increased number of drug candidates in clinical trials. A few influential pioneers have laid the foundation for advancements in the evaluation, development, and of novel purinergic P2 receptors modulators, including agonists, antagonists, pharmaceutical compositions and combination strategies, despite the different scaffolds of these drug candidates. These advancements hold great potential for improving therapeutic outcomes by specifically targeting purinergic P2 receptors.
Language	English
Publishing date	2024-03-31
Publishing country	Egypt
Document type	Journal Article ; Review
ZDB-ID	2541849-X
ISSN	2090-1224 ; 2090-1224
ISSN (online)	2090-1224
ISSN	2090-1224
DOI	10.1016/j.jare.2024.03.027
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Book ; Online: Near Space Communications (NS-COM)

Xiao, Zhenyu / Mao, Tianqi / Han, Zhu / Xia, Xiang-Gen

A New Regime in Space-Air-Ground Integrated Network (SAGIN)

2022

Abstract: Precipitated by the technological innovations of the near-space platform stations (NSPS), the near space communication (NS-COM) network has emerged as an indispensable part of the next-generation space-air-ground integrated network (SAGIN) that ... ...

Abstract	Precipitated by the technological innovations of the near-space platform stations (NSPS), the near space communication (NS-COM) network has emerged as an indispensable part of the next-generation space-air-ground integrated network (SAGIN) that facilitates ubiquitous coverage and broadband data transfer. This paper aims to provide a comprehensive overview of NS-COM. Firstly, we investigate the differences between NS-COM and the existing terrestrial cellular networks as well as satellite-based and unmanned-aerial-vehicle (UAV)-based communication networks, which is followed by a review of the NS-COM development. Then, we explore the unique characteristics of NS-COM regarding the platforms and the propagation environment of the near space. The main issues of NS-COM are identified, resulted from the extremely long transmission distance, limitations of the communication payloads on NSPS and complex atmospheric constitution of the near space. Then various application scenarios of NS-COM are discussed, where the special technical requirements are also revealed, from the physical-layer aspect like transceiver design to the upper-layer aspect like computational offloading and NSPS placement. Furthermore, we investigate the co-existence of NS-COM and ground networks by treating each other as interferers or collaborators. Finally, we list several potential technologies for NS-COM from the perspective of spectrum usage, and highlight their technical challenges for future research.
Keywords	Electrical Engineering and Systems Science - Signal Processing
Subject code	028
Publishing date	2022-07-24
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Online: Terahertz-Band Near-Space Communications

Mao, Tianqi / Zhang, Leyi / Xiao, Zhenyu / Han, Zhu / Xia, Xiang-Gen

From a Physical-Layer Perspective

2022

Abstract: Facilitated by rapid technological development of the near-space platform stations (NSPS), near-space communication (NS-COM) is envisioned to play a pivotal role in the space-air-ground integrated network for sixth-generation (6G) communications and ... ...

Abstract	Facilitated by rapid technological development of the near-space platform stations (NSPS), near-space communication (NS-COM) is envisioned to play a pivotal role in the space-air-ground integrated network for sixth-generation (6G) communications and beyond. In NS-COM, ultra-broadband wireless connectivity between NSPSs and various airborne/spaceborne platforms is required for a plethora of bandwidth-consuming applications, such as NSPS-based Ad hoc networking, in-flight Internet and relaying technology. However, such requirement seems to contradict with the scarcity of spectrum resources at conventional microwave frequencies, which motivates the exploitation of terahertz (THz) band ranging from 0.1 to 10 THz. Due to huge available bandwidth, the THz signals are capable of supporting ultra-high-rate data transmission for NS-COM over 100 Gb/s, which are naturally suitable for the near-space environment with marginal path loss. To this end, this article provides an extensive investigation on the THz-band NS-COM (THz-NS-COM) from a physical-layer perspective. Firstly, we summarize the potential applications of THz communications in the near-space environment, where the corresponding technical barriers are analyzed. Then the channel characteristics of THz-NS-COM and the corresponding modeling strategies are discussed, respectively. Afterwards, three essential research directions are investigated to surpass the technical barriers of THz-NS-COM, i.e., robust beamforming for ultra-massive antenna array, signal processing algorithms against hybrid distortions, and integrated sensing and communications. Several open problems are also provided to unleash the full potential of THz-NS-COM.
Keywords	Electrical Engineering and Systems Science - Signal Processing
Publishing date	2022-07-25
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Simulation of pedestrian evacuation route choice using social force model in large-scale public space: Comparison of five evacuation strategies.

Zhou, Jibiao / Guo, Yanyong / Dong, Sheng / Zhang, Minjie / Mao, Tianqi

PloS one

2019 Volume 14, Issue 9, Page(s) e0221872

Abstract: The primary objective of this study is to compare pedestrian evacuation strategies in the large-scale public space (LPS) using microscopic model. Data were collected by video recording from Tian-yi square for 36 hours in city of Ningbo, China. A ... ...

Abstract	The primary objective of this study is to compare pedestrian evacuation strategies in the large-scale public space (LPS) using microscopic model. Data were collected by video recording from Tian-yi square for 36 hours in city of Ningbo, China. A pedestrian evacuation simulation model was developed based on the social force model (SFM). The simulation model parameters, such as reaction time, elasticity coefficient, sliding coefficient, et al, were calibrated using the real data extracted from the video. Five evacuation strategies, strategy 1 (S1) to strategy 5 (S5) involving distance, density and capacity factors were simulated and compared by indicators of evacuation time and channel utilization rate, as well as the evacuation efficiency. The simulation model parameters calibration results showed that a) the pedestrians walking speed is 1.0 ~ 1.5m/s; b) the pedestrians walking diameter is 0.3 ~ 0.4m; c) the frequency of pedestrian arrival and departure followed multi-normal distribution. The simulation results showed that, (a) in terms of total evacuation time, the performance of S4 and S5 which considering the capacity and density factors were best in all evacuation scenarios, the performance of S3 which only considering the density factor was the worst, relatively, and S1 and S2 which considering the distance factor were in the middle. (b) the utilization rate of channels under S5 strategy was better than other strategies, which performs best in the balance of evacuation. S3 strategy was the worst, and S1, S2 and S4 were in the middle. (c) in terms of the evacuation efficiency, when the number of evacuees is within 2, 500 peds, the S1 and S2 strategy which considering the distance factor have best evacuation efficiency than other strategies. And when the number of evacuees is above 2, 500 peds, the S4 and S5 strategy which considering the capacity factor are better than others.
MeSH term(s)	Choice Behavior ; Environment ; Humans ; Models, Theoretical ; Pedestrians/psychology ; Safety ; Walking
Language	English
Publishing date	2019-09-06
Publishing country	United States
Document type	Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0221872
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Online: Cross-Domain Waveform Design for 6G Integrated Sensing and Communication

Zhang, Fan / Mao, Tianqi / Liu, Ruiqi / Han, Zhu / Dobre, Octavia A. / Chen, Sheng / Wang, Zhaocheng

2023

Abstract: Orthogonal frequency division multiplexing (OFDM) is one of the representative integrated sensing and communication (ISAC) waveforms, where sensing and communications tend to be assigned with different resource elements (REs) due to their diverse design ... ...

Abstract	Orthogonal frequency division multiplexing (OFDM) is one of the representative integrated sensing and communication (ISAC) waveforms, where sensing and communications tend to be assigned with different resource elements (REs) due to their diverse design requirements. This motivates optimization of resource allocation/waveform design across time, frequency, power and delay-Doppler domains. Therefore, this article proposes two cross-domain waveform optimization strategies for OFDM-based ISAC systems, following communication-centric and sensing-centric criteria, respectively. For the communication-centric design, to maximize the achievable data rate, a fraction of REs are optimally allocated for communications according to prior knowledge of the communication channel. The remaining REs are then employed for sensing, where the sidelobe level and peak to average power ratio are suppressed by optimizing its power-frequency and phase-frequency characteristics. For the sensing-centric design, a `locally' perfect auto-correlation property is ensured by adjusting the unit cells of the ambiguity function within its region of interest (RoI). Afterwards, the irrelevant cells beyond RoI, which can readily determine the sensing power allocation, are optimized with the communication power allocation to enhance the achievable data rate. Numerical results demonstrate the superiority of the proposed communication-centric and sensing-centric waveform designs for ISAC applications.
Keywords	Electrical Engineering and Systems Science - Signal Processing
Subject code	600
Publishing date	2023-11-08
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Online: Near-Field Sparse Channel Estimation for Extremely Large-Scale RIS-Aided Wireless Communications

Tang, Zixing / Chen, Yuanbin / Wang, Ying / Mao, Tianqi / Wu, Qingqing / Di Renzo, Marco / Hanzo, Lajos

2023

Abstract: A significant increase in the number of reconfigurable intelligent surface (RIS) elements results in a spherical wavefront in the near field of extremely large-scale RIS (XL-RIS). Although the channel matrix of the cascaded two-hop link may become sparse ...

Abstract	A significant increase in the number of reconfigurable intelligent surface (RIS) elements results in a spherical wavefront in the near field of extremely large-scale RIS (XL-RIS). Although the channel matrix of the cascaded two-hop link may become sparse in the polar-domain representation, their accurate estimation of these polar-domain parameters cannot be readily guaranteed. To tackle this challenge, we exploit the sparsity inherent in the cascaded channel. To elaborate, we first estimate the significant path-angles and distances corresponding to the common paths between the BS and the XL-RIS. Then, the individual path parameters associated with different users are recovered. This results in a two-stage channel estimation scheme, in which distinct learning-based networks are used for channel training at each stage. More explicitly, in stage I, a denoising convolutional neural network (DnCNN) is employed for treating the grid mismatches as noise to determine the true grid index of the angles and distances. By contrast, an iterative shrinkage thresholding algorithm (ISTA) based network is proposed for adaptively adjusting the column coherence of the dictionary matrix in stage II. Finally, our simulation results demonstrate that the proposed two-stage learning-based channel estimation outperforms the state-of-the-art benchmarks. Comment: This paper has been accepted for publication in the IEEE GLOBECOM 2023 Workshops Proceedings
Keywords	Electrical Engineering and Systems Science - Signal Processing
Subject code	003
Publishing date	2023-11-13
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Online: 6G Enabled Advanced Transportation Systems

Liu, Ruiqi / Hua, Meng / Guan, Ke / Wang, Xiping / Zhang, Leyi / Mao, Tianqi / Zhang, Di / Wu, Qingqing / Jamalipour, Abbas

2023

Abstract: With the emergence of communication services with stringent requirements such as autonomous driving or on-flight Internet, the sixth-generation (6G) wireless network is envisaged to become an enabling technology for future transportation systems. In this ...

Abstract	With the emergence of communication services with stringent requirements such as autonomous driving or on-flight Internet, the sixth-generation (6G) wireless network is envisaged to become an enabling technology for future transportation systems. In this paper, two ways of interactions between 6G networks and transportation are extensively investigated. On one hand, the new usage scenarios and capabilities of 6G over existing cellular networks are firstly highlighted. Then, its potential in seamless and ubiquitous connectivity across the heterogeneous space-air-ground transportation systems is demonstrated, where railways, airplanes, high-altitude platforms and satellites are investigated. On the other hand, we reveal that the introduction of 6G guarantees a more intelligent, efficient and secure transportation system. Specifically, technical analysis on how 6G can empower future transportation is provided, based on the latest research and standardization progresses in localization, integrated sensing and communications, and security. The technical challenges and insights for a road ahead are also summarized for possible inspirations on 6G enabled advanced transportation. Comment: Submitted to IEEE Transactions on Intelligent Transportation Systems (T-ITS)
Keywords	Computer Science - Information Theory ; Computer Science - Networking and Internet Architecture ; Electrical Engineering and Systems Science - Signal Processing ; Electrical Engineering and Systems Science - Systems and Control
Subject code	380
Publishing date	2023-05-24
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Receiver design for SPAD-based VLC systems under Poisson-Gaussian mixed noise model.

Mao, Tianqi / Wang, Zhaocheng / Wang, Qi

Optics express

2017 Volume 25, Issue 2, Page(s) 799–809

Abstract: Single-photon avalanche diode (SPAD) is a promising photosensor because of its high sensitivity to optical signals in weak illuminance environment. Recently, it has drawn much attention from researchers in visible light communications (VLC). However, ... ...

Abstract	Single-photon avalanche diode (SPAD) is a promising photosensor because of its high sensitivity to optical signals in weak illuminance environment. Recently, it has drawn much attention from researchers in visible light communications (VLC). However, existing literature only deals with the simplified channel model, which only considers the effects of Poisson noise introduced by SPAD, but neglects other noise sources. Specifically, when an analog SPAD detector is applied, there exists Gaussian thermal noise generated by the transimpedance amplifier (TIA) and the digital-to-analog converter (D/A). Therefore, in this paper, we propose an SPAD-based VLC system with pulse-amplitude-modulation (PAM) under Poisson-Gaussian mixed noise model, where Gaussian-distributed thermal noise at the receiver is also investigated. The closed-form conditional likelihood of received signals is derived using the Laplace transform and the saddle-point approximation method, and the corresponding quasi-maximum-likelihood (quasi-ML) detector is proposed. Furthermore, the Poisson-Gaussian-distributed signals are converted to Gaussian variables with the aid of the generalized Anscombe transform (GAT), leading to an equivalent additive white Gaussian noise (AWGN) channel, and a hard-decision-based detector is invoked. Simulation results demonstrate that, the proposed GAT-based detector can reduce the computational complexity with marginal performance loss compared with the proposed quasi-ML detector, and both detectors are capable of accurately demodulating the SPAD-based PAM signals.
Language	English
Publishing date	2017-01-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	1491859-6
ISSN	1094-4087 ; 1094-4087
ISSN (online)	1094-4087
ISSN	1094-4087
DOI	10.1364/OE.25.000799
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Article ; Online: Discovery of Selective P2Y

Zhu, Yifan / Zhou, Mengze / Cheng, Xiangyu / Wang, Hui / Li, Yehong / Guo, Yueyue / Wang, Yaxuan / Tian, Sheng / Mao, Tianqi / Zhang, Zhoudong / Li, Duxin / Hu, Qinghua / Li, Huanqiu

Journal of medicinal chemistry

2023 Volume 66, Issue 9, Page(s) 6315–6332

Abstract: As a member of purinoceptors, the ... ...

Abstract	As a member of purinoceptors, the P2Y
MeSH term(s)	Animals ; Mice ; Colitis/chemically induced ; Colitis/drug therapy ; Colitis, Ulcerative/chemically induced ; Colitis, Ulcerative/drug therapy ; Dextran Sulfate ; Inflammasomes/metabolism ; Mice, Inbred C57BL ; NLR Family, Pyrin Domain-Containing 3 Protein
Chemical Substances	Dextran Sulfate (9042-14-2) ; Inflammasomes ; NLR Family, Pyrin Domain-Containing 3 Protein ; purinoceptor P2Y6
Language	English
Publishing date	2023-04-20
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	218133-2
ISSN	1520-4804 ; 0022-2623
ISSN (online)	1520-4804
ISSN	0022-2623
DOI	10.1021/acs.jmedchem.3c00210
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