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  1. Article ; Online: Measuring social-communication difficulties in school-age siblings of children with autism spectrum disorder: Standardized versus naturalistic assessment.

    Gangi, Devon N / Hill, Monique Moore / Maqbool, Shyeena / Young, Gregory S / Ozonoff, Sally

    Autism research : official journal of the International Society for Autism Research

    2021  Volume 14, Issue 9, Page(s) 1913–1922

    Abstract: Younger siblings of children with autism spectrum disorder (ASD; high-risk siblings) are at elevated risk for developing the broader autism phenotype (BAP), which consists of subclinical features of ASD. We examined conversational skills in a ... ...

    Abstract Younger siblings of children with autism spectrum disorder (ASD; high-risk siblings) are at elevated risk for developing the broader autism phenotype (BAP), which consists of subclinical features of ASD. We examined conversational skills in a naturalistic context and standardized assessments of pragmatic language and communication skills in high-risk and low-risk school-age children with BAP (n = 22) and ASD (n = 18) outcomes, as well as comparison children without ASD or BAP (n = 135). Children with BAP characteristics exhibited lower conversational skills than comparison children, but did not differ on any of three standardized measures. Only the conversational ratings significantly predicted membership in the BAP versus Comparison group. This suggests that naturalistic tasks are crucial when assessing social-communication difficulties in children with a family history of ASD. LAY SUMMARY: The broader autism phenotype (BAP) consists of subclinical features of autism spectrum disorder (ASD) and is more common among family members of those with ASD. School-age children with BAP characteristics exhibited lower conversational skills than comparison children, but did not differ on standardized language measures tapping similar abilities. This suggests that naturalistic tasks may be more sensitive to the social-communication difficulties seen in some children with a family history of ASD than the standardized language tests used in most evaluations.
    MeSH term(s) Autism Spectrum Disorder ; Autistic Disorder ; Child ; Communication ; Humans ; Schools ; Siblings
    Language English
    Publishing date 2021-05-19
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2481338-2
    ISSN 1939-3806 ; 1939-3792
    ISSN (online) 1939-3806
    ISSN 1939-3792
    DOI 10.1002/aur.2531
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Measuring Developmental Delays: Comparison of Parent Report and Direct Testing.

    Ozonoff, Sally / Gangi, Devon / Corona, Laura / Foster, Tori / Hill, Monique Moore / Honaker, Makayla / Maqbool, Shyeena / Ni, Rachel / Nicholson, Amy / Parikh, Chandni / Stone, Caitlin / Spitler, Anna Kathleen / Swanson, Amy / Vehorn, Alison / Wagner, Liliana / Weitlauf, Amy / Warren, Zachary

    Journal of autism and developmental disorders

    2024  

    Abstract: Purpose: Developmental assessment is part of a comprehensive autism evaluation. During in-person evaluations, developmental assessment is completed via direct testing by an examiner. In telehealth evaluations, developmental assessment relies on ... ...

    Abstract Purpose: Developmental assessment is part of a comprehensive autism evaluation. During in-person evaluations, developmental assessment is completed via direct testing by an examiner. In telehealth evaluations, developmental assessment relies on caregiver-report instruments. This study examined correspondence between caregiver report and direct testing of developmental skills.
    Methods: Participants were 93 children, aged 18-42 months, undergoing evaluation for possible autism spectrum disorder (ASD). Caregivers were interviewed with the Developmental Profile, 4th edition (DP-4) via telehealth platform and children were tested in person 2-4 weeks later using the Mullen Scales of Early Learning (MSEL).
    Results: Correlations between the DP-4 and MSEL were high (ranging from 0.50 to 0.82) across standard scores, age equivalents, and functional categories, as well as across individual subtests and overall composite scores.
    Conclusion: The high convergent validity found in this study suggests that the DP-4 provides a suitable proxy for direct developmental testing using the MSEL in the context of telehealth evaluations for ASD in young children, delivering a good estimate of both developmental functioning and presence of delays.
    Trial registration: Data were obtained from registered clinical trial NCT05047224, date of registration 2021-09-07.
    Language English
    Publishing date 2024-02-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391999-7
    ISSN 1573-3432 ; 0162-3257
    ISSN (online) 1573-3432
    ISSN 0162-3257
    DOI 10.1007/s10803-024-06292-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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