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  1. Article ; Online: Telemedicina y humanización de la atención médica en la pandemia Covid-19

    Samuel Sevilla-Fuentes / María Luisa Hernández Medel

    Salud Pública de México, Vol 62, Iss 5, sep-oct, Pp 459-

    2020  Volume 461

    Abstract: ... No ... ...

    Abstract No disponible
    Keywords Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2020-08-01T00:00:00Z
    Publisher Instituto Nacional de Salud Pública
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Murine typhus in Mexico City

    Sokani Sánchez-Montes / Pablo Colunga-Salas / Edith A. Fernández-Figueroa / María Luisa Hernández Medel / César Rivera Benítez / Ingeborg Becker

    Revista do Instituto de Medicina Tropical de São Paulo, Vol 61, Iss

    report of an imported case

    2019  

    Abstract: ABSTRACT Murine typhus is endemic in several countries. We herein report an imported case of murine typhus caused by Rickettsia typhi in Mexico City. This is the first report of a case after almost 20 years since the last report. The species was ... ...

    Abstract ABSTRACT Murine typhus is endemic in several countries. We herein report an imported case of murine typhus caused by Rickettsia typhi in Mexico City. This is the first report of a case after almost 20 years since the last report. The species was confirmed by DNA sequencing and phylogenetic reconstruction.
    Keywords Rickettsiosis ; Mexico ; Rickettsia typhi ; PCR ; Arctic medicine. Tropical medicine ; RC955-962
    Language English
    Publishing date 2019-03-01T00:00:00Z
    Publisher Universidade de São Paulo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Gram-negative ESKAPE bacteria bloodstream infections in patients during the COVID-19 pandemic

    María Dolores Alcántar-Curiel / Manuel Huerta-Cedeño / Ma Dolores Jarillo-Quijada / Catalina Gayosso-Vázquez / José Luis Fernández-Vázquez / María Luisa Hernández-Medel / Manuelita Zavala-Pineda / Miguel Ángel Morales-Gil / Verónica Alejandra Hernández-Guzmán / Manuel Ismael Bolaños-Hernández / Silvia Giono-Cerezo / José Ignacio Santos-Preciado

    PeerJ, Vol 11, p e

    2023  Volume 15007

    Abstract: Bloodstream infections due to bacteria are a highly consequential nosocomial occurrences and the organisms responsible for them are usually multidrug-resistant. The aims of this study were to describe the incidence of bacteremia caused by Gram-negative ... ...

    Abstract Bloodstream infections due to bacteria are a highly consequential nosocomial occurrences and the organisms responsible for them are usually multidrug-resistant. The aims of this study were to describe the incidence of bacteremia caused by Gram-negative ESKAPE bacilli during the COVID-19 pandemic and characterize the clinical and microbiological findings including antimicrobial resistance. A total of 115 Gram-negative ESKAPE isolates were collected from patients with nosocomial bacteremia (18% of the total bacteremias) in a tertiary care center in Mexico City from February 2020 to January 2021. These isolates were more frequently derived from the Respiratory Diseases Ward (27), followed by the Neurosurgery (12), Intensive Care Unit (11), Internal Medicine (11), and Infectious Diseases Unit (7). The most frequently isolated bacteria were Acinetobacter baumannii (34%), followed by Klebsiella pneumoniae (28%), Pseudomonas aeruginosa (23%) and Enterobacter spp (16%). A. baumannii showed the highest levels of multidrug-resistance (100%), followed by K. pneumoniae (87%), Enterobacter spp (34%) and P. aeruginosa (20%). The blaCTX-M-15 and blaTEM-1 genes were identified in all beta-lactam-resistant K. pneumoniae (27), while blaTEM-1 was found in 84.6% (33/39) of A. baumannii isolates. The carbapenemase gene blaOXA-398 was predominant among carbapenem-resistant A. baumannii (74%, 29/39) and blaOXA-24was detected in four isolates. One P. aeruginosa isolate was blaVIM-2 gene carrier, while two K. pneumoniae and one Enterobacter spp were blaNDM gene carriers. Among colistin-resistant isolates mcr-1 gene was not detected. Clonal diversity was observed in K. pneumoniae, P. aeruginosa and Enterobacter spp. Two outbreaks caused by A. baumannii ST208 and ST369 were detected, both belonging to the clonal complex CC92 and IC2. A. baumannii was associated with a death rate of 72% (28/32), most of them (86%, 24/28) extensively drug-resistant or pandrug-resistant isolates, mainly in patients with COVID-19 (86%, 24/28) in the ...
    Keywords Gram-negative bacilli ; ESKAPE bacteria ; Multidrug-resistant ; COVID-19 ; Bloodstream infections ; Mexico ; Medicine ; R ; Biology (General) ; QH301-705.5
    Subject code 610
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher PeerJ Inc.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: O-26 ASPARTATE AMINOTRANSFERASE, AGE AND D-DIMER IN COVID-19 PATIENTS

    Fátima Higuera-de la Tijera / Alfredo Servín-Caamaño / Daniel Reyes-Herrera / Argelia Flores-López / Enrique J.A. Robiou-Vivero / Felipe Martínez-Rivera / Victor Galindo-Hernández / Catalina Casillas-Suárez / Oscar Chapa-Azuela / Alfonso Chávez-Morales / Víctor Hugo Rosales-Salyano / Billy Jiménez-Bobadilla / María Luisa Hernández-Medel / Benjamín Orozco-Zúñiga / Jed Raful Zacarías-Ezzat / Santiago Camacho-Hernández / José Luis Pérez-Hernández

    Annals of Hepatology, Vol 24, Iss , Pp 100513- (2021)

    A USEFUL PROGNOSTIC MODEL

    2021  

    Abstract: Introduction: Some patients with SARSCov-2 infection develop severe disease (SARS); however, the factors associated with severity are not yet fully understood. Some reports indicate that liver injury may be a poor prognostic factor. Aim: To identify the ... ...

    Abstract Introduction: Some patients with SARSCov-2 infection develop severe disease (SARS); however, the factors associated with severity are not yet fully understood. Some reports indicate that liver injury may be a poor prognostic factor. Aim: To identify the biochemical factors related to the development of SARS with mechanical ventilation (MV) requirement in patients with SARSCov-2 and COVID-19. Methods Type of study: Observational. Cohort study. Procedure: Data from COVID-19 patients were collected at admission time to a tertiary care center. Differential factors were identified between seriously ill SARS+MV patients versus stable patients without MV. Transformation to the natural logarithm of significant variables was performed and multiple linear regression was applied, then a predictive model of severity called AAD (Age-AST-D dimer) was constructed. Results: 166 patients were included, 114(68.7%) men, mean age 50.6±13.3 years-old, 27(16.3%) developed SARS+MV. In the comparative analysis between those with SARS+MV versus stable patients without MV we found significant raises of ALT (225.4±341.2 vs. 41.3±41.1; P=0.003), AST 325.3±382.4 vs. 52.8±47.1; P=0.001), LDH (764.6±401.9 vs. 461.0±185.6; P=0.001), D dimer (7765±9109 vs. 1871±4146; P=0.003), age (58.6±12.7 vs. 49.1±12.8; P=0-001). The results of the regression are shown in the Table, where model 3 was the one that best explained the development of SARS+MV; with these variables was constructed the model called AAD, where: [AAD= 3.896 + ln(age)x-0.218 + ln(AST)x-0.185 + ln(DD)x0.070], where a value ≤ 2.75 had sensitivity=0.797 and 1-specificity= 0.391, AUROC=0.74 (95%CI: 0.62-0.86; P<0.0001), to predict the risk of developing SARS+MV (OR=5.8, 95%CI: 2.2-15.4; P=0.001). Conclusions: Elevation of AST (probable marker of liver damage) is an important predictor of progression to SARS, together with elevation of D-dimer and age early (at admission) and efficiently predict which patients will potentially require MV.
    Keywords Specialties of internal medicine ; RC581-951
    Subject code 610
    Language English
    Publishing date 2021-09-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Intranasal dexamethasone

    Graciela Cárdenas / María Chávez-Canales / Ana María Espinosa / Antonio Jordán-Ríos / Daniel Anica Malagon / Manlio Fabio Márquez Murillo / Laura Victoria Torres Araujo / Ricardo Leopoldo Barajas Campos / Rosa María Wong-Chew / Luis Esteban Ramirez González / Karent Ibet Cresencio / Enrique García Velázquez / Mariana Rodriguez de la Cerda / Yoana Leyva / Joselin Hernández-Ruiz / María Luisa Hernández-Medel / Mireya León-Hernández / Karen Medina Quero / Anahí Sánchez Monciváis /
    Sergio Hernández Díaz / Ignacia Rosalia Zeron Martínez / Adriana Martínez-Cuazitl / Iván Noé Martínez Salazar / Eduardo Beltrán Sarmiento / Aldo Figueroa Peña / Patricia Saraí Hernández / Rafel Ignacio Aguilar Reynoso / Daniela Murillo Reyes / Luis Rodrigo del Río Ambriz / Rogelio Antonio Alfaro Bonilla / Jocelyn Cruz / Leonor Huerta / Nora Alma Fierro / Marisela Hernández / Mayra Pérez-Tapia / Gabriela Meneses / Erick Espíndola-Arriaga / Gabriela Rosas / Alberto Chinney / Sergio Rosales Mendoza / Juan Alberto Hernández-Aceves / Jaquelynne Cervantes-Torres / Anai Fuentes Rodríguez / Roxana Olguin Alor / Sandra Ortega Francisco / Evelyn Alvarez Salazar / Hugo Besedovsky / Marta C. Romano / Raúl J. Bobes / Helgi Jung

    Trials, Vol 23, Iss 1, Pp 1-

    a new clinical trial for the control of inflammation and neuroinflammation in COVID-19 patients

    2022  Volume 11

    Abstract: Highlights REVIVAL is a multicenter, open-label, randomized, controlled study to compare the standard low doses of intravenous dexamethasone with weight-adjusted low doses of intranasal dexamethasone. Intranasal dexamethasone can reach the respiratory ... ...

    Abstract Highlights REVIVAL is a multicenter, open-label, randomized, controlled study to compare the standard low doses of intravenous dexamethasone with weight-adjusted low doses of intranasal dexamethasone. Intranasal dexamethasone can reach the respiratory tract more effectively than intravenous administration. Intranasal dexamethasone can reach the central nervous system in therapeutic concentrations, even at low doses. REVIVAL aims to reduce central failures and sequelae by controlling not only systemic inflammation but also neuroinflammation.
    Keywords Dexamethasone ; Intranasal administration ; Inflammation ; Neuroinflammation ; COVID-19 ; Medicine (General) ; R5-920
    Language English
    Publishing date 2022-02-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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