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  1. AU="Marazuela, Rosario"
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  3. AU="Mahadevan, L"
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  5. AU=Kyriazopoulou Evdoxia AU=Kyriazopoulou Evdoxia
  6. AU="Kalezić, Tanja"
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  11. AU="Maclean, Ilya M. D."
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  14. AU="Ricci, Giampietro"
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  1. Artikel: Legislación, ética y trasplante renal.

    Valentín, María O / Pérez Blanco, Alicia / Marazuela, Rosario / Domínguez-Gil, Beatriz

    Archivos espanoles de urologia

    2021  Band 74, Heft 10, Seite(n) 910–921

    Abstract: Kidney transplantation (KT) is the best therapeutic option for patients with end-stage renal disease in terms of survival, quality of life and cost-effectiveness. The fundamental difference of KT with respect to other therapies is that the process ... ...

    Titelübersetzung Legislaction, ethics and kidney transplantation.
    Abstract Kidney transplantation (KT) is the best therapeutic option for patients with end-stage renal disease in terms of survival, quality of life and cost-effectiveness. The fundamental difference of KT with respect to other therapies is that the process depends on the availability of organs for clinical use, availability that is insufficient to cover the increasing transplantation needs of the population. Another relevant feature of transplantation is that it entails a risk of transmission of diseases from donor to recipient, a risk that can be minimized, but not completely eliminated. Due to its characteristics and its unique nature (the human being), KT requires a specific regulation that guarantees the protection of all those who participate in the process: donors and their families, patients in need of a transplant, recipients of organs and healthcareprofessionals involved. In this article, we reviewthe ethical-legal standards that regulate the practice of kidney donation and transplantation at the international level and analyze the ethical-legal framework that is applicable in Spain.
    Mesh-Begriff(e) Humans ; Kidney Failure, Chronic/surgery ; Kidney Transplantation ; Quality of Life ; Tissue Donors ; Tissue and Organ Procurement
    Sprache Spanisch
    Erscheinungsdatum 2021-11-23
    Erscheinungsland Spain
    Dokumenttyp Journal Article ; Review
    ZDB-ID 211673-x
    ISSN 0004-0614
    ISSN 0004-0614
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Addressing Risks Derived From the Commodification of Substances of Human Origin: A European Proposal Applicable Worldwide.

    Cuende, Natividad / Vilarrodona, Anna / Vuelta, Elena / Marazuela, Rosario / Herrera, Concha / Querol, Sergi / Sánchez-Ibáñez, Jacinto / Carmona, Mar / Gayá, Antonio / Tort, Jaume / Hernández, Dolores / Domínguez-Gil, Beatriz

    Transplantation

    2023  Band 107, Heft 4, Seite(n) 867–877

    Abstract: In view of the public consultation recently launched by the World Health Organization on Regulatory Convergence of Cell and Gene Therapy Products and the Proposal for a Regulation on substances of human origin (SoHO) repealing the European Union ... ...

    Abstract In view of the public consultation recently launched by the World Health Organization on Regulatory Convergence of Cell and Gene Therapy Products and the Proposal for a Regulation on substances of human origin (SoHO) repealing the European Union Directives on Blood and on Tissues and Cells, an opportunity arises to define an ethical and transparent framework of collaboration between industry and authorities responsible for SoHO-derived products, comprising medicines, medical devices, transfusion, and transplantation. The commodification of SoHO-derived medicinal products and medical devices entails important risks to the sustainability of healthcare systems and threatens the equitable access of patients to innovative therapies. It may also jeopardize the principle of altruistic donation of SoHO that is required for the treatment and survival of thousands of patients every year. This article puts forward several proposals aimed at reconciling the ethical principles of voluntary and unpaid SoHO donation and the noncommercialization of the human body with obtaining a profit that allows business activities, while ensuring high quality, safety, and efficacy standards of tissues and cells for clinical use.
    Mesh-Begriff(e) Humans ; Commodification ; Blood Transfusion ; Altruism ; Reference Standards
    Sprache Englisch
    Erscheinungsdatum 2023-02-01
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000004527
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Benchmarking in organ donation after brain death in Spain.

    Matesanz, Rafael / Domínguez-Gil, Beatriz / Marazuela, Rosario / Coll, Elisabeth / de la Rosa, Gloria

    Lancet (London, England)

    2012  Band 380, Heft 9842, Seite(n) 649–650

    Mesh-Begriff(e) Benchmarking/methods ; Brain Death ; Humans ; Spain ; Tissue Donors/supply & distribution ; Tissue and Organ Procurement/standards
    Sprache Englisch
    Erscheinungsdatum 2012-08-18
    Erscheinungsland England
    Dokumenttyp Letter
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(12)61371-3
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Spanish experience as a leading country: what kind of measures were taken?

    Matesanz, Rafael / Domínguez-Gil, Beatriz / Coll, Elisabeth / de la Rosa, Gloria / Marazuela, Rosario

    Transplant international : official journal of the European Society for Organ Transplantation

    2011  Band 24, Heft 4, Seite(n) 333–343

    Abstract: A recent call for self-sufficiency in transplantation issued by the WHO faces variable worldwide activity, in which Spain occupies a privileged position, with deceased donation rates of 33-35per million population (pmp) and 85 transplants pmp. An ... ...

    Abstract A recent call for self-sufficiency in transplantation issued by the WHO faces variable worldwide activity, in which Spain occupies a privileged position, with deceased donation rates of 33-35per million population (pmp) and 85 transplants pmp. An evaluation of current challenges, including a decrease in deaths because of traffic accidents and cerebrovascular diseases, and a diversity of cultures in Spain, has been followed by a comprehensive strategy to increase organ availability. Actions include an earlier referral of possible donors to the transplant coordination teams, a benchmarking project to identify critical success factors in donation after brain death, new family approach and care methods, and the development of additional training courses aimed at specific groups of professionals, supported by their corresponding societies. Consensus documents to improve knowledge about safety limits for organ donation have been developed to minimize inappropriate discarding of organs. Use of organs from expanded criteria donors under an 'old for old' allocation policy has resulted from adaptation to the progressive decline of optimal organs. National strategic plans to deal better with organ shortage, while respecting solid ethical standards, are essential, as reflected in the WHO Guiding Principles and the Istanbul Declaration on Organ Trafficking and Transplant tourism.
    Mesh-Begriff(e) Accidents, Traffic/mortality ; Brain Death ; Death ; Humans ; Living Donors/supply & distribution ; Organ Transplantation/statistics & numerical data ; Spain/epidemiology ; Tissue Donors/supply & distribution ; Tissue and Organ Procurement/organization & administration ; Tissue and Organ Procurement/statistics & numerical data
    Sprache Englisch
    Erscheinungsdatum 2011-04
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 639435-8
    ISSN 1432-2277 ; 0934-0874
    ISSN (online) 1432-2277
    ISSN 0934-0874
    DOI 10.1111/j.1432-2277.2010.01204.x
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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