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  1. Article: Editorial: Conduction system pacing: What's missing for the paradigm shift?

    Marcantoni, Lina / Zanon, Francesco / Anselmino, Matteo

    Frontiers in cardiovascular medicine

    2023  Volume 10, Page(s) 1163370

    Language English
    Publishing date 2023-03-24
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2023.1163370
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: The weakest point of cardiac resynchronization therapy: new technologies facing old terminology.

    Marcantoni, Lina / Pastore, Gianni / Biffi, Mauro / Zanon, Francesco

    Frontiers in cardiovascular medicine

    2023  Volume 10, Page(s) 1236369

    Abstract: Patients with symptomatic heart failure (HF) and left bundle branch block (LBBB) are currently treated with biventricular pacing (BiV) which has a Class IA recommendation. Given the possibility to re-establish the inter and intra-ventricular synchrony, ... ...

    Abstract Patients with symptomatic heart failure (HF) and left bundle branch block (LBBB) are currently treated with biventricular pacing (BiV) which has a Class IA recommendation. Given the possibility to re-establish the inter and intra-ventricular synchrony, BiV is commonly referred to as cardiac resynchronization therapy (CRT). This wording is widely utilized and over time the terms BiV and CRT have become interchangeable. Conduction system pacing (CSP) is emerging as a valid therapeutic opportunity to obtain CRT restoring the native conduction via the Purkinje network. Therefore the acronym CRT is no longer synonymous with BiV only but could also refer to CSP. A terminology update is needed to include the resource of CSP to ensure better communication among all the stakeholders involved in managing recipients of cardiac devices and should be a fundamental step in advancing the quality of patient care. Making use of the NBG code to describe the implantable cardiac device would ease such terminology update, since only the first three positions of the five letters NBG code are commonly utilized, while the last two are rarely used.
    Language English
    Publishing date 2023-08-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2023.1236369
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  3. Article ; Online: Simple approaches to reduce radiation in the electrophysiology laboratory replay.

    Zanon, Francesco / Marcantoni, Lina

    Journal of cardiovascular electrophysiology

    2020  Volume 31, Issue 9, Page(s) 2546–2547

    MeSH term(s) Bundle of His ; Cardiac Pacing, Artificial ; Electrophysiology ; Fluoroscopy ; Humans ; Laboratories
    Language English
    Publishing date 2020-06-09
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1025989-2
    ISSN 1540-8167 ; 1045-3873
    ISSN (online) 1540-8167
    ISSN 1045-3873
    DOI 10.1111/jce.14586
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2863: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  4. Article: Conduction system pacing in difficult cardiac anatomies: Systematic approach with the 3D electroanatomic mapping guide.

    Marcantoni, Lina / Centioni, Marco / Pastore, Gianni / Aneris, Federico / Baracca, Enrico / Zanon, Francesco

    Indian pacing and electrophysiology journal

    2023  Volume 23, Issue 6, Page(s) 177–182

    Abstract: Introduction: Restoring physiological cardiac electrical activity in patients with conduction disease can be crucial for the survival and quality of life. Conduction system pacing (CSP) is a valuable option, although it is limited by technical ... ...

    Abstract Introduction: Restoring physiological cardiac electrical activity in patients with conduction disease can be crucial for the survival and quality of life. Conduction system pacing (CSP) is a valuable option, although it is limited by technical challenges in difficult anatomies. 3D electroanatomical mapping (3D-EAM) can support CSP ensuring high electro-anatomical precision and low fluoroscopy.
    Objectives: We evaluated the feasibility and effectiveness of a systematic 3D-EAM use to guide CSP in difficult anatomical scenarios (highly dilated atria, congenital cardiomyopathies, failed biventricular implants (BiV) and pacing-induced cardiomyopathy (PICM)).
    Methods: Forty-three consecutive patients (27 males, 75 ± 10 years old) with standard pacing indications and difficult anatomical scenarios were included. The right atrium, His cloud, and atrio-ventricular septum were reconstructed by 3D-EAM. The His bundle (HB) was the initial target, while left bundle branch area pacing (LBBAP) was aimed at in case of unsatisfactory parameters, sub-optimally paced QRS, or impossibility of reaching the HB.
    Results: CSP was successful in 37 (86%) patients (15 HBP; 22 LBBAP). Mean mapping, fluoroscopy, and procedural times were 18 ± 7 min, 7 ± 5 min, 98 ± 47 min, respectively. The mean pacing threshold, R wave sensing, and pacing impedance of CSP lead were 1.2 ± 0.5V@0.5ms, 11.4 ± 6.2 mV, 736 ± 306 Ω, respectively. Baseline and paced QRS were 139 ± 38 ms and 114 ± 23 ms, respectively. No procedural complications were observed.
    Conclusions: 3D-EAM allowed the accurate definition of the His cloud and high ventricular septum and effectively guided CSP. It facilitated CSP in complex anatomies, with a procedural success rate of 86%. The results were satisfactory and reproducible, with acceptable fluoroscopy and procedural times.
    Language English
    Publishing date 2023-08-18
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2123606-9
    ISSN 0972-6292
    ISSN 0972-6292
    DOI 10.1016/j.ipej.2023.08.006
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  5. Article ; Online: His Bundle Pacing: My Experience, Tricks, and Tips.

    Zanon, Francesco / Marcantoni, Lina / Centioni, Marco / Pastore, Gianni / Baracca, Enrico

    Cardiac electrophysiology clinics

    2022  Volume 14, Issue 2, Page(s) 141–149

    Abstract: His Bundle Pacing (HBP) is a form of physiologic pacing achieved through implantation of a pacing electrode into the His bundle. HBP began 20 years ago without any dedicated tools. As specific tools became available HBP quickly spread and proved to be a ... ...

    Abstract His Bundle Pacing (HBP) is a form of physiologic pacing achieved through implantation of a pacing electrode into the His bundle. HBP began 20 years ago without any dedicated tools. As specific tools became available HBP quickly spread and proved to be a viable alternative to traditional right ventricle pacing. HBP is reliable and effective in preserving the physiologic ventricular synchrony with clinical benefits particularly evident when a high percentage of pacing is required. Unipolar signals from the lead tip guide the implant. 3D electroanatomical mapping could further assist the procedure.
    MeSH term(s) Bundle of His ; Cardiac Pacing, Artificial/methods ; Electrocardiography ; Heart Ventricles/surgery ; Humans ; Treatment Outcome
    Language English
    Publishing date 2022-05-25
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1877-9190
    ISSN (online) 1877-9190
    DOI 10.1016/j.ccep.2021.12.016
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  6. Article: Left bundle branch pacing by standard stylet-driven lead: Preliminary experience of two case reports.

    Zanon, Francesco / Marcantoni, Lina / Pastore, Gianni / Baracca, Enrico

    HeartRhythm case reports

    2020  Volume 6, Issue 9, Page(s) 614–617

    Keywords covid19
    Language English
    Publishing date 2020-06-15
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834871-0
    ISSN 2214-0271
    ISSN 2214-0271
    DOI 10.1016/j.hrcr.2020.06.005
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  7. Article ; Online: His bundle pacing: the myth is approaching standard medical care.

    Zanon, Francesco / Pastore, Gianni / Marcantoni, Lina

    Revista espanola de cardiologia (English ed.)

    2020  Volume 73, Issue 8, Page(s) 611–614

    MeSH term(s) Bundle of His ; Bundle-Branch Block/therapy ; Cardiac Catheterization ; Cardiac Pacing, Artificial ; Electrocardiography ; Humans
    Language Spanish
    Publishing date 2020-03-05
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 2592481-3
    ISSN 1885-5857 ; 1885-5857
    ISSN (online) 1885-5857
    ISSN 1885-5857
    DOI 10.1016/j.rec.2020.01.010
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  8. Article: Pacing of the specialized His-Purkinje conduction system: 'back to the future'.

    Bressi, Edoardo / Grieco, Domenico / Čurila, Karol / Zanon, Francesco / Marcantoni, Lina / Cabrera, Jose Angel / De Ruvo, Ermenegildo / Vernooy, Kevin / Calò, Leonardo

    European heart journal supplements : journal of the European Society of Cardiology

    2023  Volume 25, Issue Suppl C, Page(s) C234–C241

    Abstract: The conduction system of the human heart is composed of specialized cardiomyocytes that initiate and propagate the electric impulse with consequent rhythmic and synchronized contraction of the atria and ventricles, resulting in the normal cardiac cycle. ... ...

    Abstract The conduction system of the human heart is composed of specialized cardiomyocytes that initiate and propagate the electric impulse with consequent rhythmic and synchronized contraction of the atria and ventricles, resulting in the normal cardiac cycle. Although the His-Purkinje system (HPS) was already described more than a century ago, there has been a recent resurgence of conduction system pacing (CSP), where pacing leads are positioned in the His bundle region and left bundle branch area to provide physiological cardiac activation as alternatives to the unnatural myocardial stimulation obtained with conventional right ventricular and biventricular pacing. In this review, we describe the fundamental anatomical and pathophysiological aspects of the specialized HPS along with the CSP technique's nuts and bolts to highlight its potential benefits in everyday clinical practice.
    Language English
    Publishing date 2023-04-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 1463769-8
    ISSN 1554-2815 ; 1520-765X
    ISSN (online) 1554-2815
    ISSN 1520-765X
    DOI 10.1093/eurheartjsupp/suad047
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1563 -Suppl.-: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  9. Article ; Online: Transvenous lead extraction of lumenless 3830 pacing lead in conduction system pacing: a single-center experience.

    Migliore, Federico / Pittorru, Raimondo / De Lazzari, Manuel / Tarzia, Vincenzo / Pastore, Gianni / Marcantoni, Lina / Catanzariti, Domenico / Gerosa, Gino / Zanon, Francesco

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

    2023  Volume 67, Issue 1, Page(s) 175–182

    Abstract: Background: The Medtronic SelectSecure Model 3830 lumenless lead (Medtronic, Inc., Minneapolis, MN) is commonly used for conduction system pacing (CSP). However, with this increased use, the potential need for transvenous lead extraction (TLE) also will ...

    Abstract Background: The Medtronic SelectSecure Model 3830 lumenless lead (Medtronic, Inc., Minneapolis, MN) is commonly used for conduction system pacing (CSP). However, with this increased use, the potential need for transvenous lead extraction (TLE) also will increase. While extraction of endocardial 3830 leads is rather well described especially in pediatric and adult congenital heart disease population, there is very limited data on extraction of CSP leads. In the present study, we reported our preliminary experience on TLE of CSP leads and provided technical considerations.
    Methods: The study population comprised 6 consecutive patients (67% male; mean age 70 ± 22 years) with CSP leads (3830 leads), including left bundle branch pacing (LBBP) lead (n = 3) and His pacing lead (n = 3) undergoing TLE. Overall target leads were 17. The mean implant duration time of CSP leads was 97 ± 90 months [range 8-193).
    Results: Manual traction was successful in 2 cases and mechanical extraction tools were required in the remaining cases. Sixteen leads (94%) were completely extracted, whereas incomplete removal was observed in one lead (6%) among 1 patient. Of note, in the only lead incompletely removed, we observed retention of < 1-cm remnant of lead material consisting of the screw of 3830 LBBP lead into the interventricular septum. No failure of lead extraction was reported and no major complications occurred.
    Conclusions: Our findings demonstrated that at an experienced center the success of TLE of chronically implanted CSP leads is high in the absence of major complications also when mechanical extraction tools are needed.
    MeSH term(s) Humans ; Male ; Adult ; Child ; Middle Aged ; Aged ; Aged, 80 and over ; Female ; Pacemaker, Artificial ; Retrospective Studies ; Device Removal ; Heart Defects, Congenital/surgery ; Cardiac Pacing, Artificial ; Cardiac Conduction System Disease
    Language English
    Publishing date 2023-06-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1329179-8
    ISSN 1572-8595 ; 1383-875X
    ISSN (online) 1572-8595
    ISSN 1383-875X
    DOI 10.1007/s10840-023-01590-0
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5214: Show issues Location:
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  10. Article ; Online: Troponin assessment in patients admitted to the emergency department with atrial fibrillation: which role in daily clinical practice?

    Zanon, Francesco / Giatti, Sara / Zuin, Marco / Marcantoni, Lina

    Internal and emergency medicine

    2018  Volume 13, Issue 3, Page(s) 319–320

    MeSH term(s) Atrial Fibrillation ; Emergency Service, Hospital ; Hospitalization ; Humans ; Troponin
    Chemical Substances Troponin
    Language English
    Publishing date 2018
    Publishing country Italy
    Document type Letter ; Comment
    ZDB-ID 2454173-4
    ISSN 1970-9366 ; 1828-0447
    ISSN (online) 1970-9366
    ISSN 1828-0447
    DOI 10.1007/s11739-018-1789-y
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