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Article ; Online: Intralesional application of ribavirin in two American flamingos (Phoenicopterus ruber) with poxvirus infection.

Marcello, Giuseppe M / Holder, Kali A / Hallager, Sara / Norton, Benjamin B / Backues, Kay A / Tyler, Anna E / Zeitlin, Ayo / Murray-Hiteshew, Evan / Murray, Suzan

Journal of comparative pathology

2023  Volume 201, Page(s) 49–52

Abstract: We report the successful treatment of poxvirus lesions in two juvenile American flamingos (Phoenicopterus ruber) with experimental low-dose intralesional ribavirin injection. In the first flamingo, the size and location of a beak verrucosity interfered ... ...

Abstract We report the successful treatment of poxvirus lesions in two juvenile American flamingos (Phoenicopterus ruber) with experimental low-dose intralesional ribavirin injection. In the first flamingo, the size and location of a beak verrucosity interfered with feeding, and after multiple surgical interventions, an experimental therapy of low-dose intralesional ribavirin was implemented with close blood parameter monitoring to minimize any potential side effects due to systemic antiviral administration. The second flamingo had a poxvirus lesion on the tibiotarsus, which recurred after unsuccessful conservative medical treatment and surgical intervention and a course of intralesional ribavirin therapy was implemented. Regression of the lesions in both flamingos commenced within 3 days of ribavirin treatment resulting in complete resolution within 6 weeks of onset of ribavirin treatment.
MeSH term(s) Animals ; Ribavirin ; Bird Diseases/pathology ; Poxviridae Infections/pathology ; Poxviridae Infections/veterinary ; Birds
Chemical Substances Ribavirin (49717AWG6K)
Language English
Publishing date 2023-01-25
Publishing country England
Document type Journal Article
ZDB-ID 390920-7
ISSN 1532-3129 ; 0021-9975
ISSN (online) 1532-3129
ISSN 0021-9975
DOI 10.1016/j.jcpa.2022.11.004
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