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  1. Article ; Online: Anaesthetic and surgical management of rib fractures.

    Williams, A / Bigham, C / Marchbank, A

    BJA education

    2020  Volume 20, Issue 10, Page(s) 332–340

    Language English
    Publishing date 2020-07-23
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2888911-3
    ISSN 2058-5357 ; 2058-5349
    ISSN (online) 2058-5357
    ISSN 2058-5349
    DOI 10.1016/j.bjae.2020.06.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A review of the best method of leg wound closure following open harvesting of the long saphenous vein for coronary artery bypass grafting.

    Panahi, Pedram / Ilyas, Ali Adeeb / Lloyd, Clinton / Marchbank, Adrian / Unsworth-White, Jonathan

    Annals of medicine and surgery (2012)

    2021  Volume 70, Page(s) 102855

    Abstract: Uncertainty exists around the optimal method of leg wound closure following open long saphenous vein harvesting in adults undergoing coronary artery bypass graft surgery (CABG). Such is evident from the variety observed in the closure approach utilised. ... ...

    Abstract Uncertainty exists around the optimal method of leg wound closure following open long saphenous vein harvesting in adults undergoing coronary artery bypass graft surgery (CABG). Such is evident from the variety observed in the closure approach utilised. Consequently, a best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was 'following open long saphenous vein harvesting in adults undergoing CABG, is single-layer leg wound closure superior to multiple-layer closure in terms of post-operative complications encountered? '. Altogether 382 papers on Ovid Embase and Ovid Medline, 301 papers on PubMed and 11 papers on the Cochrane database were found using the reported search. From the screened articles, 6 represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated. We conclude that the best method of leg closure following open saphenous vein harvesting for CABG is single-layer cutaneous closure. The use of a suction drain to eliminate the dead space should be considered on a case-to-case basis by the lead operating surgeon with the patient's characteristics and their own expertise in mind.
    Language English
    Publishing date 2021-09-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2745440-X
    ISSN 2049-0801
    ISSN 2049-0801
    DOI 10.1016/j.amsu.2021.102855
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Molecular insights into high-altitude adaption and acclimatisation of

    Perry, Iain / Hernadi, Szabolcs Balazs / Cunha, Luis / Short, Stephen / Marchbank, Angela / Spurgeon, David J / Orozco-terWengel, Pablo / Kille, Peter

    Life science alliance

    2022  Volume 5, Issue 11

    Abstract: Here, we explore the high-altitude adaptions and acclimatisation ... ...

    Abstract Here, we explore the high-altitude adaptions and acclimatisation of
    MeSH term(s) Adaptation, Physiological/genetics ; Altitude ; Animals ; Genome ; Oligochaeta
    Language English
    Publishing date 2022-08-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2575-1077
    ISSN (online) 2575-1077
    DOI 10.26508/lsa.202201513
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Seasonal and ontological variation in diet and age-related differences in prey choice, by an insectivorous songbird.

    Davies, Sarah R / Vaughan, Ian P / Thomas, Robert J / Drake, Lorna E / Marchbank, Angela / Symondson, William O C

    Ecology and evolution

    2022  Volume 12, Issue 8, Page(s) e9180

    Abstract: The diet of an individual animal is subject to change over time, both in response to short-term food fluctuations and over longer time scales as an individual ages and meets different challenges over its life cycle. A metabarcoding approach was used to ... ...

    Abstract The diet of an individual animal is subject to change over time, both in response to short-term food fluctuations and over longer time scales as an individual ages and meets different challenges over its life cycle. A metabarcoding approach was used to elucidate the diet of different life stages of a migratory songbird, the Eurasian reed warbler (
    Language English
    Publishing date 2022-08-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2635675-2
    ISSN 2045-7758
    ISSN 2045-7758
    DOI 10.1002/ece3.9180
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Left lower lobe torsion following upper lobectomy-prompt recognition and treatment improve survival.

    Alassar, Aiman / Marchbank, Adrian

    Journal of surgical case reports

    2014  Volume 2014, Issue 8

    Abstract: Lobar torsion is a rare but life-threatening complication after lung resection. We report a case of left lower lobe torsion in 57-year-old women after upper lobectomy for underlying lung cancer. Definitive diagnosis of lung torsion was made at ... ...

    Abstract Lobar torsion is a rare but life-threatening complication after lung resection. We report a case of left lower lobe torsion in 57-year-old women after upper lobectomy for underlying lung cancer. Definitive diagnosis of lung torsion was made at exploratory thoracotomy following abnormal chest radiography and bronchoscopy on the first post-operative day. An emergency completion pneumonectomy was performed and left lower lobe was resected. The post-operative course was uncomplicated and patient was discharged home on the seventh post-operative day. Early recognition and prompt treatment of lobar torsion is essential for preventing potentially catastrophic complications including fatal gangrene of the pulmonary lobe.
    Language English
    Publishing date 2014-08-11
    Publishing country England
    Document type Case Reports
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rju078
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Multi-marker DNA metabarcoding reveals spatial and sexual variation in the diet of a scarce woodland bird.

    Stenhouse, Ewan H / Bellamy, Paul / Kirby, Will / Vaughan, Ian P / Drake, Lorna E / Marchbank, Angela / Workman, Trudy / Symondson, William O C / Orozco-terWengel, Pablo

    Ecology and evolution

    2023  Volume 13, Issue 5, Page(s) e10089

    Abstract: Avian diet can be affected by site-specific variables, such as habitat, as well as intrinsic factors such as sex. This can lead to dietary niche separation, which reduces competition between individuals, as well as impacting how well avian species can ... ...

    Abstract Avian diet can be affected by site-specific variables, such as habitat, as well as intrinsic factors such as sex. This can lead to dietary niche separation, which reduces competition between individuals, as well as impacting how well avian species can adapt to environmental variation. Estimating dietary niche separation is challenging, due largely to difficulties in accurately identifying food taxa consumed. Consequently, there is limited knowledge of the diets of woodland bird species, many of which are undergoing serious population declines. Here, we show the effectiveness of multi-marker fecal metabarcoding to provide in-depth dietary analysis of a declining passerine in the UK, the Hawfinch (
    Language English
    Publishing date 2023-05-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2635675-2
    ISSN 2045-7758
    ISSN 2045-7758
    DOI 10.1002/ece3.10089
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Fluorocarbon emulsions.

    Marchbank, A

    Perfusion

    1995  Volume 10, Issue 2, Page(s) 67–88

    Abstract: Perfluorocarbon emulsions have been the topic of intense investigation for many years and presently there are still no absolute indications for their use in clinical practice. The relatively disappointing results of the early clinical studies, as a ... ...

    Abstract Perfluorocarbon emulsions have been the topic of intense investigation for many years and presently there are still no absolute indications for their use in clinical practice. The relatively disappointing results of the early clinical studies, as a consequence of using low concentrations of a relatively underdeveloped emulsion, have been responsible for a largely negative impression and it is now essential that the newer second generation emulsions should be judged individually with regard to their efficacy and toxicity under different circumstances. Technological advancement in the fields of chemistry and detergent/emulsifier research will continue and new formulations are being developed which which will require to be tested in models in the laboratory. In the future, this class of drugs will continue to be the topic of intense investigation and their mechanisms of action, which are undoubtedly more complex than the simple carriage of dissolved gases in solution, will be clarified. However, whether fluorocarbon emulsions will ever be used as a 'blood substitute' as was originally anticipated is doubtful.
    MeSH term(s) Anemia/drug therapy ; Animals ; Cardioplegic Solutions ; Fluorocarbons/chemistry ; Fluorocarbons/pharmacokinetics ; Fluorocarbons/therapeutic use ; Hemorrhage/drug therapy ; Humans ; Materials Testing ; Myocardial Ischemia/drug therapy ; Myocardial Reperfusion Injury
    Chemical Substances Cardioplegic Solutions ; Fluorocarbons
    Language English
    Publishing date 1995-03
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 645038-6
    ISSN 1477-111X ; 0267-6591
    ISSN (online) 1477-111X
    ISSN 0267-6591
    DOI 10.1177/026765919501000203
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Effectiveness of a gentamicin impregnated collagen sponge on reducing sternal wound infections following cardiac surgery: a meta-analysis of randomised controlled trials.

    Creanor, S / Barton, A / Marchbank, A

    Annals of the Royal College of Surgeons of England

    2012  Volume 94, Issue 4, Page(s) 227–231

    Abstract: Introduction: Gentamicin impregnated collagen sponges are licensed for use after cardiac surgery in over 50 countries but their effectiveness at preventing sternal wound infections (SWIs) remains uncertain. The aim of this meta-analysis was to assess ... ...

    Abstract Introduction: Gentamicin impregnated collagen sponges are licensed for use after cardiac surgery in over 50 countries but their effectiveness at preventing sternal wound infections (SWIs) remains uncertain. The aim of this meta-analysis was to assess the current evidence for effectiveness of such sponges at preventing SWIs in patients after cardiac surgery.
    Methods: A systematic search of the literature was undertaken and meta-analyses were performed on the results of the identified, eligible studies. Using random effects models, odds ratios (OR) and corresponding 95% confidence intervals (CI) were calculated for all SWIs and deep SWIs for: a) all participants, and b) participants deemed as high risk.
    Results: Three unique randomised controlled trials (published between 2005 and 2010) involving 3,994 participants met the inclusion criteria. There was insufficient evidence of a significant difference between intervention and control groups for all SWIs (all participants: OR: 0.66, 95% CI: 0.39-1.14; high risk participants: OR: 0.60, 95% CI: 0.24-1.52). There was insufficient evidence of a significant benefit of the sponge in deep SWIs across all participants (OR: 0.72, 95% CI: 0.47-1.10) but some evidence of benefit in terms of reducing the incidence of deep SWIs in high risk participants (OR: 0.62, 95% CI: 0.39-0.98).
    Conclusions: There is insufficient evidence of the effectiveness (or otherwise) of gentamicin impregnated sponges in preventing SWIs following cardiac surgery. However, some evidence does exist that such sponges can reduce the incidence of deep infections in high risk patients.
    MeSH term(s) Anti-Bacterial Agents/administration & dosage ; Cardiac Surgical Procedures/methods ; Collagen/therapeutic use ; Gentamicins/administration & dosage ; Humans ; Randomized Controlled Trials as Topic ; Risk Factors ; Sternum ; Surgical Sponges ; Surgical Wound Infection/prevention & control ; Treatment Outcome
    Chemical Substances Anti-Bacterial Agents ; Gentamicins ; Collagen (9007-34-5)
    Language English
    Publishing date 2012-05-09
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Review
    ZDB-ID 80044-2
    ISSN 1478-7083 ; 0035-8843
    ISSN (online) 1478-7083
    ISSN 0035-8843
    DOI 10.1308/003588412X13171221590179
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Pulmonary Metastasectomy in Colorectal Cancer: updated analysis of 93 randomized patients - control survival is much better than previously assumed.

    Milosevic, M / Edwards, J / Tsang, D / Dunning, J / Shackcloth, M / Batchelor, T / Coonar, A / Hasan, J / Davidson, B / Marchbank, A / Grumett, S / Williams, N R / Macbeth, F / Farewell, V / Treasure, T

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2020  Volume 22, Issue 10, Page(s) 1314–1324

    Abstract: Aim: Lung metastases from colorectal cancer are resected in selected patients in the belief that this confers a significant survival advantage. It is generally assumed that the 5-year survival of these patients would be near zero without metastasectomy. ...

    Abstract Aim: Lung metastases from colorectal cancer are resected in selected patients in the belief that this confers a significant survival advantage. It is generally assumed that the 5-year survival of these patients would be near zero without metastasectomy. We tested the clinical effectiveness of this practice in Pulmonary Metastasectomy in Colorectal Cancer (PulMiCC), a randomized, controlled noninferiority trial.
    Method: Multidisciplinary teams in 14 hospitals recruited patients with resectable lung metastases into a two-arm trial. Randomization was remote and stratified according to site, with minimization for age, sex, primary cancer stage, interval since primary resection, prior liver involvement, number of metastases and carcinoembryonic antigen level. The trial management group was blind to patient allocation until after intention-to-treat analysis.
    Results: From 2010 to 2016, 93 participants were randomized. These patients were 35-86 years of age and had between one and six lung metastases at a median of 2.7 years after colorectal cancer resection; 29% had prior liver metastasectomy. The patient groups were well matched and the characteristics of these groups were similar to those of observational studies. The median survival after metastasectomy was 3.5 (95% CI: 3.1-6.6) years compared with 3.8 (95% CI: 3.1-4.6) years for controls. The estimated unadjusted hazard ratio for death within 5 years, comparing the metastasectomy group with the control group, was 0.93 (95% CI: 0.56-1.56). Use of chemotherapy or local ablation was infrequent and similar in each group.
    Conclusion: Patients in the control group (who did not undergo lung metastasectomy) have better survival than is assumed. Survival in the metastasectomy group is comparable with the many single-arm follow-up studies. The groups were well matched with features similar to those reported in case series.
    MeSH term(s) Colorectal Neoplasms/pathology ; Colorectal Neoplasms/surgery ; Humans ; Lung Neoplasms/surgery ; Metastasectomy ; Neoplasm Staging ; Retrospective Studies ; Survival Rate
    Language English
    Publishing date 2020-06-14
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.15113
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Flower senescence in composite flowers, can understanding how dahlia florets senesce help to increase dahlia vase life?

    Casey, M / Tansey, K. E / Andrews, R / Marchbank, A / Rogers, H. J / Stead, A. D

    Acta horticulturae. 2019, , no. 1263

    2019  

    Abstract: The dahlia is popular as an ornamental garden plant in the UK, however, its value as a cut flower has been undermined by its short vase life. The vase life of dahlias is often no more than 5 days, whereas 10-14 days are required by the cut flower ... ...

    Abstract The dahlia is popular as an ornamental garden plant in the UK, however, its value as a cut flower has been undermined by its short vase life. The vase life of dahlias is often no more than 5 days, whereas 10-14 days are required by the cut flower industry due to the supply chain involved in transporting cut flowers from growers to retailers, sufficient time in store, and still guaranteeing 5 days vase life to a consumer. The current study has considered ethylene sensitivity and how phytohormones interact with one another during the senescence process. In conjunction with these traditional methods, RNA sequencing and de novo assembly of the dahlia transcriptome in the cultivar 'Sylvia' has been carried out, resulting in an assembly of over 20,000 genes, many of which change in expression during floret senescence.
    Keywords cultivars ; cut flowers ; ethylene ; florets ; genes ; growers ; industry ; ornamental plants ; sequence analysis ; supply chain ; transcriptome ; vase life
    Language English
    Size p. 383-390.
    Publishing place International Society for Horticultural Science.
    Document type Article
    Note Paper presented at the XXX International Horticultural Congress IHC2018: International Symposium on Ornamental Horticulture and XI International Symposium on Postharvest Quality of Ornamental Plants held August 12, 2018, Istanbul, Turkey
    ISSN 0567-7572
    DOI 10.17660/ActaHortic.2019.1263.50
    Database NAL-Catalogue (AGRICOLA)

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