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  1. Article ; Online: EARLY RETINAL MANIFESTATIONS PRECEDING ACUTE SYPHILITIC POSTERIOR PLACOID CHORIORETINITIS.

    Harrell, Michael / Marchese, Alessandro / Jampol, Lee M

    Retinal cases & brief reports

    2024  

    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Journal Article
    ISSN 1937-1578
    ISSN (online) 1937-1578
    DOI 10.1097/ICB.0000000000001566
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Ocular complications of SAVI: A unique case of bilateral uveitis and retinal vasculitis.

    Menean, Matteo / Marchese, Alessandro / Modorati, Giulio / Favale, Rosa / Boscia, Francesco / Bandello, Francesco / Miserocchi, Elisabetta

    American journal of ophthalmology case reports

    2024  Volume 34, Page(s) 102046

    Abstract: Purpose: To describe a case of bilateral panuveitis in a patient with Stimulator of Interferon Genes (STING)-Associated Vasculitis with Onset in Infancy (SAVI).: Observations: A 45-year-old patient diagnosed with SAVI presented bilateral panuveitis ... ...

    Abstract Purpose: To describe a case of bilateral panuveitis in a patient with Stimulator of Interferon Genes (STING)-Associated Vasculitis with Onset in Infancy (SAVI).
    Observations: A 45-year-old patient diagnosed with SAVI presented bilateral panuveitis and uncontrolled secondary intraocular hypertension due to structural complications from uveitis. Multimodal imaging revealed the presence of intraretinal fluid and bilateral vasculitis. The patient was started with systemic methotrexate.
    Conclusions and importance: This case is essential to characterize ocular involvement in patients with SAVI. Awareness of these ocular manifestations is crucial for timely management and improvement of visual prognosis.
    Language English
    Publishing date 2024-04-10
    Publishing country United States
    Document type Case Reports
    ISSN 2451-9936
    ISSN (online) 2451-9936
    DOI 10.1016/j.ajoc.2024.102046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: DISAPPEARING CHOROIDAL SPOTS ON OCT ANGIOGRAPHY PRECEDING RECURRENCE OF MULTIFOCAL CHOROIDITIS WITH CHORIORETINAL ATROPHY.

    Marchese, Alessandro / Bar-Meir, Avram / Jampol, Lee M / Mirza, Rukhsana G

    Retinal cases & brief reports

    2023  

    Abstract: Purpose: To describe idiopathic multifocal choroiditis (iMFC) with chorioretinal atrophy developing choroidal flow voids on optical coherence tomography angiography (OCTA) that preceded a recurrence of the disease.: Methods: Case report.: Results: ...

    Abstract Purpose: To describe idiopathic multifocal choroiditis (iMFC) with chorioretinal atrophy developing choroidal flow voids on optical coherence tomography angiography (OCTA) that preceded a recurrence of the disease.
    Methods: Case report.
    Results: A 24-year-old woman presented with visual field changes and occasional photopsias. Systemic work-up for syphilis, tuberculosis, and sarcoidosis, was negative. Clinical findings and multimodal imaging were consistent with iMFC with chorioretinal atrophy, complicated by inactive choroidal neovascularization in her right eye. She was treated with systemic corticosteroids with a taper over 3 months without change in her examination. She was then stable for two years. At that point, the patient experienced increased photopsias, but her examination was unchanged. OCTA showed multiple flow voids in the choroid that were not present 6 months prior. No lesions were seen on other imaging modalities. Structural OCT showed some subtle hyper-reflectivity throughout the choroid that was previously absent. Given the unknown significance of these flow voids, the patient was asked to return for follow-up in one month. Her photopsias improved and her vision remained normal. On repeat examination after one month, the patient had developed a few subtle yellow lesions in the supero-nasal quadrant of the left eye. There were no macular lesions. The repeat OCTA revealed that the flow voids were fading.
    Conclusion: Imaging findings using OCTA in our patient with iMFC showed choroidal flow voids that preceded clinical recurrence, not detected by other imaging modalities. Future studies should determine if OCTA can be used to detect subclinical lesions preceding clinical recurrences of iMFC.
    Language English
    Publishing date 2023-09-23
    Publishing country United States
    Document type Journal Article
    ISSN 1937-1578
    ISSN (online) 1937-1578
    DOI 10.1097/ICB.0000000000001501
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: JIGSAW RETINOPATHY.

    Marchese, Alessandro / Harrell, Michael / Jampol, Lee M / Jain, Nieraj / O'Keefe, Ghazala A D

    Retina (Philadelphia, Pa.)

    2023  Volume 44, Issue 3, Page(s) 545–549

    Language English
    Publishing date 2023-08-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603192-4
    ISSN 1539-2864 ; 0275-004X
    ISSN (online) 1539-2864
    ISSN 0275-004X
    DOI 10.1097/IAE.0000000000003910
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    Zs.A 1724: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  5. Article ; Online: Anterior segment involvement in vitreoretinal lymphoma: clinical manifestations, molecular findings and in vivo confocal microscopy.

    Marchese, Alessandro / Di Biase, Carlo / Cicinelli, Maria Vittoria / Menean, Matteo / Ferrari, Giulio / Bandello, Francesco / Modorati, Giulio / Goldstein, Debra Anne / Miserocchi, Elisabetta

    The British journal of ophthalmology

    2024  

    Abstract: Background: Intermediate and posterior manifestations of vitreoretinal lymphoma (VRL) are well characterised. However, there is limited information on anterior segment involvement in VRL. This study aimed to describe the anterior manifestations of VRL, ... ...

    Abstract Background: Intermediate and posterior manifestations of vitreoretinal lymphoma (VRL) are well characterised. However, there is limited information on anterior segment involvement in VRL. This study aimed to describe the anterior manifestations of VRL, and their association with molecular testing.
    Methods: Retrospective analysis of patients with biopsy-proven VRL. Study variables included anterior segment manifestations, findings from slit-lamp photos and in vivo confocal microscopy (IVCM) when available. MYD88 L265P mutation and cytology in the aqueous humour, retinal and systemic findings were also analysed.
    Results: The analysis included 108 eyes of 55 VRL patients. Anterior segment involvement was present in at least one visit in 55 eyes (51%) of 33 patients (60%); it included keratic precipitates (dendritiform with branching and irregular margins in 33 eyes, dust-like in 16 eyes and large granulomatous in 12 eyes), cells in the anterior chamber (51 eyes) and posterior synechiae (2 eyes). IVCM was available for 41 eyes and showed different morphologies of keratic precipitates, including floral, spikes and mulberry patterns (66%, 56% and 20%, respectively). MYD88 L265P mutation in the aqueous humour was detected in 10/21 (48%) eyes with no anterior segment involvement and 24/37 (65%) eyes with anterior segment involvement.
    Conclusions: Anterior segment manifestations are often present in VRL and include dendritiform and dust-like keratic precipitates. IVCM in VRL can identify different patterns associated with keratic precipitates. MYD88 L265P mutation in the aqueous humour of VRL patients can also be found in eyes without significant anterior segment involvement.
    Language English
    Publishing date 2024-01-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 80078-8
    ISSN 1468-2079 ; 0007-1161
    ISSN (online) 1468-2079
    ISSN 0007-1161
    DOI 10.1136/bjo-2023-324303
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ul I Zs.83: Show issues Location:
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  6. Article ; Online: Refining the Removal of Perfluorocarbon Liquid Remnants Through Negative Staining With Vital Dyes.

    Coppola, Michele / Marchese, Alessandro / Bandello, Francesco

    Ophthalmic surgery, lasers & imaging retina

    2021  Volume 52, Issue 3, Page(s) 153–154

    Abstract: The complete removal of perfluorocarbon liquid (PFCL) after complex vitreoretinal surgery can be a challenging task. However, it remains a crucial step to avoid several ocular complications associated with retained PFCL. In this report, the authors ... ...

    Abstract The complete removal of perfluorocarbon liquid (PFCL) after complex vitreoretinal surgery can be a challenging task. However, it remains a crucial step to avoid several ocular complications associated with retained PFCL. In this report, the authors describe a simple and effective technique to highlight the presence of retained PFCL bubbles in the epiretinal space through negative staining with vital dyes.
    MeSH term(s) Coloring Agents ; Fluorocarbons ; Humans ; Negative Staining ; Retinal Detachment/surgery ; Vitrectomy
    Chemical Substances Coloring Agents ; Fluorocarbons
    Language English
    Publishing date 2021-03-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701167-7
    ISSN 2325-8179 ; 2325-8160
    ISSN (online) 2325-8179
    ISSN 2325-8160
    DOI 10.3928/23258160-20210302-06
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 756: Show issues Location:
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  7. Article: Choroidal vascularization and adrenergic innervation qualitative findings obtained with induced fluorescence preparations and optical coherence tomography angiography: possible correlations and perspectives.

    Nuzzi, Raffaele / Tridico, Federico / Marchese, Alessandro / Bandello, Francesco

    International journal of retina and vitreous

    2020  Volume 6, Issue 1, Page(s) 61

    Abstract: Background: Recent advances in optical coherence tomography (OCT) technology allow a more accurate choroidal visualization. The aim of this study is to provide histochemical analysis with induced fluorescence images of the choroidal stromal, vascular ... ...

    Abstract Background: Recent advances in optical coherence tomography (OCT) technology allow a more accurate choroidal visualization. The aim of this study is to provide histochemical analysis with induced fluorescence images of the choroidal stromal, vascular and nerve network, highlighting possible correspondences with OCT and OCT angiography (OCT-A) analysis.
    Methods: The material examined with a histochemical process of induced fluorescence through condensation of biologically active monoamines with glyoxylic acid was obtained from 6 eyes enucleated for malignant melanoma and ciliary body neoplasia. The resulting images have been qualitatively compared with OCT and OCT-A choroidal images obtained from 10 volunteers, in order to identify possible relationships. Choriocapillary segmentation was performed automatically through the embedded analysis software, while segmentation of Sattler's and Haller's layers was performed through a manual method.
    Results: Histochemical analysis provided accurate visualization of choroidal adrenergic innervation across all layers and its relationships with blood vessels and melanocytes. The above structures were not visualized at OCT and OCT-A which provided good visualization of blood vessels in Sattler's and Haller's layers as well-delimited hyporeflective areas. Decorrelation signal was not detected in OCT-A analysis due to low blood flow velocity in external choroidal layers.
    Conclusions: The choroid is an extremely dynamic structure which deserves to be analyzed in vivo since it is involved in the pathogenesis of several ocular conditions. Direct evaluation of the activity of choroidal nerves and melanocytes is still not possible with OCT and OCT-A, even if they are capable of providing a satisfactory representation of choroidal vascularization.
    Language English
    Publishing date 2020-11-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2836254-8
    ISSN 2056-9920
    ISSN 2056-9920
    DOI 10.1186/s40942-020-00255-8
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  8. Article ; Online: Loss of the Figure 8 Appearance on OCT: A Useful Clue for Leukemic Retinopathy.

    Marchese, Alessandro / Agarwal, Aniruddha / Gupta, Vishali

    Ophthalmology. Retina

    2020  Volume 4, Issue 3, Page(s) 237

    MeSH term(s) Female ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/complications ; Retina/pathology ; Retinal Diseases/diagnosis ; Retinal Diseases/etiology ; Retinal Vessels/pathology ; Tomography, Optical Coherence/methods ; Young Adult
    Language English
    Publishing date 2020-03-04
    Publishing country United States
    Document type Case Reports ; Journal Article
    ISSN 2468-6530
    ISSN (online) 2468-6530
    DOI 10.1016/j.oret.2019.12.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Correspondence.

    Arrigo, Alessandro / Pierro, Luisa / Marchese, Alessandro / Bandello, Francesco

    Retina (Philadelphia, Pa.)

    2020  Volume 41, Issue 2, Page(s) e19

    MeSH term(s) Humans ; Retina
    Language English
    Publishing date 2020-07-26
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 603192-4
    ISSN 1539-2864 ; 0275-004X
    ISSN (online) 1539-2864
    ISSN 0275-004X
    DOI 10.1097/IAE.0000000000002929
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    Zs.A 1724: Show issues Location:
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  10. Article ; Online: Polypoidal choroidal vasculopathy invading the optic disc.

    Marchese, Alessandro / Bandello, Francesco / Querques, Giuseppe

    Indian journal of ophthalmology

    2020  Volume 68, Issue 11, Page(s) 2532

    MeSH term(s) Choroid ; Choroid Diseases/diagnosis ; Choroidal Neovascularization/diagnosis ; Fluorescein Angiography ; Humans ; Indocyanine Green ; Optic Disk
    Chemical Substances Indocyanine Green (IX6J1063HV)
    Language English
    Publishing date 2020-10-23
    Publishing country India
    Document type Journal Article
    ZDB-ID 187392-1
    ISSN 1998-3689 ; 0301-4738
    ISSN (online) 1998-3689
    ISSN 0301-4738
    DOI 10.4103/ijo.IJO_937_19
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    Zs.B 329: Show issues Location:
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    Zs.MO 598: Show issues

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