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Article ; Online: Promoting the Use of Modern Communication Tools to Increase Vaccine Uptake in Pregnancy.

Triunfo, Stefania / Marconi, Anna Maria

2023 Volume 177, Issue 8, Page(s) 870–871

MeSH term(s)	Female ; Pregnancy ; Humans ; Vaccines ; Vaccination ; Communication
Chemical Substances	Vaccines
Language	English
Publishing date	2023-06-20
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	2701223-2
ISSN	2168-6211 ; 2168-6203
ISSN (online)	2168-6211
ISSN	2168-6203
DOI	10.1001/jamapediatrics.2023.1807
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Article ; Online: Recent advances in the induction of labor.

Marconi, Anna Maria

F1000Research

2019 Volume 8

Abstract: The rate of labor induction is steadily increasing and, in industrialized countries, approximately one out of four pregnant women has their labor induced. Induction of labor should be considered when the benefits of prompt vaginal delivery outweigh the ... ...

Abstract	The rate of labor induction is steadily increasing and, in industrialized countries, approximately one out of four pregnant women has their labor induced. Induction of labor should be considered when the benefits of prompt vaginal delivery outweigh the maternal and/or fetal risks of waiting for the spontaneous onset of labor. However, this procedure is not free of risks, which include an increase in operative vaginal or caesarean delivery and excessive uterine activity with risk of fetal heart rate abnormalities. A search for "Induction of Labor" retrieves more than 18,000 citations from 1844 to the present day. The aim of this review is to summarize the controversies concerning the indications, the methods, and the tools for evaluating the success of the procedure, with an emphasis on the scientific evidence behind each.
MeSH term(s)	Cesarean Section ; Female ; Humans ; Labor, Induced ; Oxytocics ; Pregnancy
Chemical Substances	Oxytocics
Language	English
Publishing date	2019-10-30
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2699932-8
ISSN	2046-1402 ; 2046-1402
ISSN (online)	2046-1402
ISSN	2046-1402
DOI	10.12688/f1000research.17587.1
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Article: Editorial: Functional hypothalamic amenorrhea seen from different perspectives.

Garzia, Emanuele / Marconi, Anna Maria / Lania, Andrea / Miozzo, Monica Rosa / Vegni, Elena / Priori, Alberto

Frontiers in endocrinology

2023 Volume 14, Page(s) 1167668

MeSH term(s)	Female ; Humans ; Amenorrhea/etiology ; Polycystic Ovary Syndrome ; Hypogonadism
Language	English
Publishing date	2023-04-06
Publishing country	Switzerland
Document type	Editorial
ZDB-ID	2592084-4
ISSN	1664-2392
ISSN	1664-2392
DOI	10.3389/fendo.2023.1167668
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Article ; Online: Robotic multiple sigmoid and rectal mucosa skinning in a multicentric deep infiltrating bowel endometriotic nodules: a case report.

Gaia, Giorgia / Afonina, Margarita / Sighinolfi, Maria Chiara / Formisano, Giampaolo / Bianchi, Paolo Pietro / Marconi, Anna Maria

Journal of minimally invasive surgery

2023 Volume 26, Issue 3, Page(s) 146–150

Abstract: Endometriosis is a benign gynecological disease characterized by the presence of endometrial tissue outside the uterus. The eradication of non-gynecological localizations represents the real surgical challenge. A 29-year-old woman underwent robotic ... ...

Abstract	Endometriosis is a benign gynecological disease characterized by the presence of endometrial tissue outside the uterus. The eradication of non-gynecological localizations represents the real surgical challenge. A 29-year-old woman underwent robotic surgery with the Da Vinci system (Intuitive Surgical Inc.) for a diagnosis of stage IV deep endometriosis. The patient presented with 5 cm left ovarian endometrioma, an infiltration of the left posterior parametrium, and bilateral ureteral endometriosis. Once inside the pelvic cavity, deep intestinal infiltrating endometriosis implants were confirmed as triple, multicentric, and multifocal lesions, affected distal sigmoid, rectosigmoid junction, and upper rectum. An expert multiple excision, sparing the intestinal mucosa, was performed. To our knowledge, this is the first description of a multiple robotic shaving of multicentric endometriotic intestinal lesions. After the surgery, a normal diet was quickly restored, accelerating the recovery of the physiological peristalsis and the overall recovery time.
Language	English
Publishing date	2023-09-15
Publishing country	Korea (South)
Document type	Case Reports
ISSN	2234-5248
ISSN (online)	2234-5248
DOI	10.7602/jmis.2023.26.3.146
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Article ; Online: Reducing vaccine hesitancy in pregnancy by the health literacy model inclusive of modern communication tools.

Triunfo, Stefania / Iannuzzi, Veronica / Podda, Martina / Pedrina, Deborah / Gemelli, Simona / Marconi, Anna Maria

Archives of gynecology and obstetrics

2023 Volume 308, Issue 5, Page(s) 1391–1393

Abstract: Albeit the vaccination is one of the most successful and cost-effective public health interventions, reluctance or refusal to vaccinate represents one of the ten threats to global health by the World Health Organization. Additional efforts to promote ... ...

Abstract	Albeit the vaccination is one of the most successful and cost-effective public health interventions, reluctance or refusal to vaccinate represents one of the ten threats to global health by the World Health Organization. Additional efforts to promote vaccination are required for at higher risk categories, such as pregnant women. Our approach supports the role of a clear and transparent communication by using efficient interventions and educational strategies to increase both willingness and confidence for preventable diseases in neonates and infants by vaccinations in pregnancy.
MeSH term(s)	Pregnancy ; Infant ; Infant, Newborn ; Humans ; Female ; Health Literacy ; Vaccination Hesitancy ; Communication ; Vaccination
Language	English
Publishing date	2023-08-08
Publishing country	Germany
Document type	Journal Article
ZDB-ID	896455-5
ISSN	1432-0711 ; 0932-0067
ISSN (online)	1432-0711
ISSN	0932-0067
DOI	10.1007/s00404-023-07138-x
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Article ; Online: COVID-19 does not stop obstetrics: what we need to change to go on safely birthing. The experience of a University Obstetrics and Gynecology Department in Milan.

Alfieri, Nikita / Manodoro, Stefano / Marconi, Anna Maria

Journal of perinatal medicine

2020 Volume 48, Issue 9, Page(s) 997–1000

Abstract: Since SARS-COV-2 appeared in Wuhan City, China and rapidly spread throughout Europe, a real revolution occurred in the daily routine and in the organization of the entire health system. While non-urgent clinical services have been reduced as far as ... ...

Abstract	Since SARS-COV-2 appeared in Wuhan City, China and rapidly spread throughout Europe, a real revolution occurred in the daily routine and in the organization of the entire health system. While non-urgent clinical services have been reduced as far as possible, all kind of specialists turned into COVID-19 specialists. Obstetric assistance cannot be suspended and, at the same time, safety must be guaranteed. In addition, as COVID-19 positive pregnant patients require additional care, some of the clinical habits need to be changed to face emerging needs for a vulnerable but unstoppable kind of patients. We report the management set up in an Obstetrics and Gynecology Unit during the COVID-19 era in a University Hospital in Milan, Italy.
MeSH term(s)	Betacoronavirus ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/therapy ; Delivery, Obstetric/methods ; Female ; Gynecology/methods ; Gynecology/organization & administration ; Hospitals, University/organization & administration ; Humans ; Italy/epidemiology ; Obstetrics/methods ; Obstetrics/organization & administration ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/therapy ; Postnatal Care/methods ; Pregnancy ; Pregnancy Complications, Infectious/diagnosis ; Pregnancy Complications, Infectious/prevention & control ; Pregnancy Complications, Infectious/virology ; Prenatal Care/methods ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-07-06
Publishing country	Germany
Document type	Journal Article
ZDB-ID	123512-6
ISSN	1619-3997 ; 0300-5577 ; 0936-174X
ISSN (online)	1619-3997
ISSN	0300-5577 ; 0936-174X
DOI	10.1515/jpm-2020-0218
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Article ; Online: 37% of child survivors of intrauterine or neonatal insults experience at least one long-term sequela, the most common being neurodevelopmental delay.

Marconi, Anna Maria

Evidence-based nursing

2013 Volume 16, Issue 3, Page(s) 75–76

MeSH term(s)	Developmental Disabilities/etiology ; Female ; Fetal Diseases ; Humans ; Infant, Newborn, Diseases ; Pregnancy
Language	English
Publishing date	2013-07
Publishing country	England
Document type	Comment ; Journal Article
ZDB-ID	1425988-6
ISSN	1468-9618 ; 1367-6539
ISSN (online)	1468-9618
ISSN	1367-6539
DOI	10.1136/eb-2012-100701
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Article ; Online: Hyperandrogenism and menstrual imbalance are the best predictors of metformin response in PCOS patients.

Garzia, Emanuele / Galiano, Valentina / Marfia, Giovanni / Navone, Stefania / Grossi, Enzo / Marconi, Anna Maria

Reproductive biology and endocrinology : RB&E

2022 Volume 20, Issue 1, Page(s) 6

Abstract: Background: Moving from the correlation between insulin-resistance and PCOS, metformin has been administered in some PCOS women improving ovulatory and metabolic functions and decreasing androgen levels. Inconsistency and unpredictability of response to ...

Abstract	Background: Moving from the correlation between insulin-resistance and PCOS, metformin has been administered in some PCOS women improving ovulatory and metabolic functions and decreasing androgen levels. Inconsistency and unpredictability of response to metformin limit its extensive use. Aim of this study was to identify reliable predictors of response to metformin therapy for weight loss and reduction in plasma androgen levels using ANNs (artificial neural networks). Methods: One hundred eight consecutive women with PCOS (ESHRE/ASRM 2003 Rotterdam criteria) treated with metformin 1500 mg/day, at inclusion and every 6 months underwent to a complete clinical, endocrine/metabolic assessment and ultrasonographic evaluation. Therapy outcomes were BMI reduction (≥1 kg/m Results: At 6 months 54 out of 103 (52,4%) obese patients showed BMI reduction and 45 out of 89 (50,6%) hyperandrogenemic women showed FAI decrease. The further response rates at 12 months were 30,6 and 47%, respectively. SCMs showed a clear polarization for both the outcomes with elevated accuracy. Treatment responsiveness resulted strictly related to oligo-amenorrhea and hyperandrogenemia at baseline. In addition, lower serum testosterone levels at baseline were found to be the major predictor of treatment discontinuation. Conclusions: In women with PCOS, menstrual pattern imbalance and ovarian androgens excess are the best predictors of metformin response. They may pave the way for a rethinking of the criteria for evaluating hyperandrogenism in order to better define the large population included in the diagnosis of PCOS. Baseline plasma testosterone level can serve as a sensitive marker to predict treatment compliance.
MeSH term(s)	Adult ; Biomarkers, Pharmacological ; Blood Glucose/drug effects ; Blood Glucose/metabolism ; Female ; Humans ; Hyperandrogenism/diagnosis ; Hyperandrogenism/etiology ; Hypoglycemic Agents/therapeutic use ; Insulin Resistance/physiology ; Italy ; Longitudinal Studies ; Menstruation Disturbances/diagnosis ; Menstruation Disturbances/etiology ; Metformin/therapeutic use ; Polycystic Ovary Syndrome/complications ; Polycystic Ovary Syndrome/diagnosis ; Polycystic Ovary Syndrome/drug therapy ; Prognosis ; Treatment Outcome ; Young Adult
Chemical Substances	Biomarkers, Pharmacological ; Blood Glucose ; Hypoglycemic Agents ; Metformin (9100L32L2N)
Language	English
Publishing date	2022-01-04
Publishing country	England
Document type	Clinical Trial ; Journal Article
ZDB-ID	2119215-7
ISSN	1477-7827 ; 1477-7827
ISSN (online)	1477-7827
ISSN	1477-7827
DOI	10.1186/s12958-021-00876-0
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Article ; Online: Cesarean section rate is a matter of maternal age or parity?

Marconi, Anna Maria / Manodoro, Stefano / Cipriani, Sonia / Parazzini, Fabio

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

2020 Volume 35, Issue 15, Page(s) 2972–2975

Abstract: Objective: To determine the impact of women's age on the cesarean section (CS) rate according to Robson groups 1, 2A, 3 and 4A.: Study design: Retrospective cohort study of term, livebirth, singleton pregnancies with spontaneous or induced labor who ... ...

Abstract	Objective: To determine the impact of women's age on the cesarean section (CS) rate according to Robson groups 1, 2A, 3 and 4A. Study design: Retrospective cohort study of term, livebirth, singleton pregnancies with spontaneous or induced labor who delivered at the San Paolo Hospital from 1996 through 2019, and had the Robson group assigned. Women were grouped in 5 age classes (≤24, 25-29, 30-34, 35-39 and ≥40 years). The primary outcome was the rate of CS. Results: 24 843 women were included: 36.4% classified as Robson group 1, 18.9% as Robson group 2A, 34.4% as Robson group 3 and 10.2% as Robson group 4A. The CS rate of women in Robson groups 1, 2A, 3 and 4A was 6.6%, 21.8%, 1.6% and 4.3% respectively. In nulliparous women [Robson groups 1 and 2A] group 1, the adjusted OR of CS increased steadily from 30 to ≥40 years, when compared to women aged 25-29 years. On the contrary, in multiparous women [Robson groups 3 and 4A] significant increased OR were present only for women ≥40 years. In young women [≤24 years] there was a significant reduction in the number of cesarean sections only in Robson group 1. Conclusion: The results of our study show that multiparous women aged ≥40, either in spontaneous or induced labor have an independent twofold increased risk of delivering by cesarean section when compared to women of 25-29 years. On the contrary, in nulliparous women, the risk slightly, but significantly, increases with age and again becomes twofold in women ≥40 years.
MeSH term(s)	Cesarean Section ; Female ; Humans ; Labor, Induced ; Maternal Age ; Parity ; Pregnancy ; Retrospective Studies
Language	English
Publishing date	2020-08-12
Publishing country	England
Document type	Journal Article
ZDB-ID	2077261-0
ISSN	1476-4954 ; 1057-0802 ; 1476-7058
ISSN (online)	1476-4954
ISSN	1057-0802 ; 1476-7058
DOI	10.1080/14767058.2020.1803264
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Article ; Online: Stem Cells in Clinical Trials for Pelvic Floor Disorders: a Systematic Literature Review.

Manodoro, Stefano / Frigerio, Matteo / Barba, Marta / Bosio, Sara / de Vitis, Luigi Antonio / Marconi, Anna Maria

Reproductive sciences (Thousand Oaks, Calif.)

2021 Volume 29, Issue 6, Page(s) 1710–1720

Abstract: Pelvic floor disorders (PFDs) include a series of conditions that can be poorly tolerated, negatively affecting the quality of life. Current treatment options show unsatisfactory results and new ones are therefore needed. Stem cell (SC) therapy might be ... ...

Abstract	Pelvic floor disorders (PFDs) include a series of conditions that can be poorly tolerated, negatively affecting the quality of life. Current treatment options show unsatisfactory results and new ones are therefore needed. Stem cell (SC) therapy might be an alternative treatment strategy. This systematic review aims to define the state of art of SC therapy for PFDs in clinical trials, by systematically reviewing the available evidence. A systematic search strategy was conducted up to November 7, 2020, in PubMed, Scopus, Cochrane Library, and ISI Web of Science. Preclinical studies on animal models were not considered. Studies were included when the patients were affected by any PFDs and cells were isolated, cultured, and characterized as SC. The study protocol was registered in PROSPERO (CRD42020216551). A total of 11 prospective clinical studies were included in the final assessment, specifically 7 single-arm studies dealing with SC therapy for stress urinary incontinence and 4 with anal incontinence. Among the latter, there were two prospective, single-arm studies and two randomized controlled trials. No papers concerning the use of SC for prolapse repair were retrieved. Due to the great heterogeneity, data pooling was not possible. Stem cell injection resulted in a safe procedure, with few mild adverse side effects, mostly related to harvesting sites. However, a clear beneficial impact of SC treatment for the treatment of pelvic floor disorders could not be demonstrated. Further larger targeted studies with control arms are needed before any conclusions can be made.
MeSH term(s)	Animals ; Female ; Humans ; Pelvic Floor ; Pelvic Floor Disorders/therapy ; Prospective Studies ; Quality of Life ; Stem Cells
Language	English
Publishing date	2021-10-01
Publishing country	United States
Document type	Journal Article ; Review ; Systematic Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2276411-2
ISSN	1933-7205 ; 1933-7191
ISSN (online)	1933-7205
ISSN	1933-7191
DOI	10.1007/s43032-021-00745-6
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