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Book ; Online: Entre espace public et espace privé : les élites en représentation

Marcos, Susana

(Études)

2018

Series title	Études
Keywords	Ancient history: to c 500 CE ; élite ; représentation ; Rome antique
Language	0\|f
Size	1 electronic resource (159 pages)
Publisher	Presses universitaires de Perpignan
Publishing place	Perpignan
Document type	Book ; Online
Note	French ; Open Access
HBZ-ID	HT021617711
ISBN	9782354123079 ; 2354123078
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: Improving pseudophakic optical quality beyond aspheric intraocular lenses: the next frontier.

Marcos, Susana

Journal of cataract and refractive surgery

2021 Volume 47, Issue 9, Page(s) 1111–1114

MeSH term(s)	Humans ; Lens Implantation, Intraocular ; Lenses, Intraocular
Language	English
Publishing date	2021-09-01
Publishing country	United States
Document type	Editorial
ZDB-ID	632744-8
ISSN	1873-4502 ; 0886-3350
ISSN (online)	1873-4502
ISSN	0886-3350
DOI	10.1097/j.jcrs.0000000000000762
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Article ; Online: Estimation of Crystalline Lens Material Properties From Patient Accommodation Data and Finite Element Models.

de la Hoz, Andres / Martinez-Enriquez, Eduardo / Marcos, Susana

Investigative ophthalmology & visual science

2024 Volume 64, Issue 11, Page(s) 31

Abstract: Purpose: The mechanical properties of the crystalline lens are related to its optical function of accommodation, and their changes with age are one of the potential causes for presbyopia. We estimated the mechanical parameters of the crystalline lens ... ...

Abstract	Purpose: The mechanical properties of the crystalline lens are related to its optical function of accommodation, and their changes with age are one of the potential causes for presbyopia. We estimated the mechanical parameters of the crystalline lens using quantitative optical coherence tomography (OCT) imaging and wavefront sensing data from accommodating participants and computer modeling. Methods: Full-lens shape data (from quantitative swept-source OCT and eigenlens representation) and optical power data (from Hartmann-Shack wavefront sensor) were obtained from 11 participants (22-30 years old) for relaxed accommodation at infinity and -4.5 D accommodative demand. Finite element models of lens, capsular bag, zonulae, and ciliary body were constructed using measured lens geometry and literature data, assuming a 60-mN radial force. An inverse modeling scheme was used to determine the shear moduli of the nucleus and cortex of the lens, such that the simulated deformed (maximally stretched) lens matched the participant's lens at -4.5 D. Results: The shear moduli of the nucleus and cortex were 1.62 ± 1.32 and 8.18 ± 5.63 kPa, on average, respectively. The shear modulus of the nucleus was lower than that of the cortex for all participants evaluated. The average of the two moduli per participant was statistically significantly correlated with age (R2 = 0.76, P = 0.0049). Conclusions: In vivo imaging and mechanical modeling of the crystalline lens allow estimations of the crystalline lens' mechanical properties. Differences between nuclear and cortical moduli and their dependency with age appear to be critical in accommodative function and likely in its impairment in presbyopia.
MeSH term(s)	Humans ; Male ; Female ; Lens, Crystalline/diagnostic imaging ; Accommodation, Ocular ; Finite Element Analysis ; Presbyopia ; Tomography, Optical Coherence/methods ; Computer Simulation ; Healthy Volunteers ; Adult
Language	English
Publishing date	2024-02-19
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	391794-0
ISSN	1552-5783 ; 0146-0404
ISSN (online)	1552-5783
ISSN	0146-0404
DOI	10.1167/iovs.64.11.31
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Article: Effect of fixational eye movements in corneal topography measurements with optical coherence tomography.

de Castro, Alberto / Martínez-Enríquez, Eduardo / Marcos, Susana

Biomedical optics express

2023 Volume 14, Issue 5, Page(s) 2138–2152

Abstract: There is an increasing interest in applying optical coherence tomography (OCT) to quantify the topography of ocular structures. However, in its most usual configuration, OCT data is acquired sequentially while a beam is scanned through the region of ... ...

Abstract	There is an increasing interest in applying optical coherence tomography (OCT) to quantify the topography of ocular structures. However, in its most usual configuration, OCT data is acquired sequentially while a beam is scanned through the region of interest, and the presence of fixational eye movements can affect the accuracy of the technique. Several scan patterns and motion correction algorithms have been proposed to minimize this effect, but there is no consensus on the ideal parameters to obtain a correct topography. We have acquired corneal OCT images with raster and radial patterns, and modeled the data acquisition in the presence of eye movements. The simulations replicate the experimental variability in shape (radius of curvature and Zernike polynomials), corneal power, astigmatism, and calculated wavefront aberrations. The variability of the Zernike modes is highly dependent on the scan pattern, with higher variability in the direction of the slow scan axis. The model can be a useful tool to design motion correction algorithms and to determine the variability with different scan patterns.
Language	English
Publishing date	2023-04-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	2572216-5
ISSN	2156-7085
ISSN	2156-7085
DOI	10.1364/BOE.486460
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Article ; Online: Computational simulation of the optical performance of an EDOF intraocular lens in post-LASIK eyes.

Lago, Carmen M / de Castro, Alberto / Marcos, Susana

Journal of cataract and refractive surgery

2023 Volume 49, Issue 11, Page(s) 1153–1159

Abstract: Purpose: To evaluate computationally the optical performance of AcrySof IQ Vivity extended depth-of-focus (EDOF) intraocular lenses (IOLs) in post-laser in situ keratomileusis (LASIK) eyes.: Setting: Visual Optics and Biophotonics Laboratory, Madrid, ...

Abstract	Purpose: To evaluate computationally the optical performance of AcrySof IQ Vivity extended depth-of-focus (EDOF) intraocular lenses (IOLs) in post-laser in situ keratomileusis (LASIK) eyes. Setting: Visual Optics and Biophotonics Laboratory, Madrid, Spain. Design: Experimental study. Methods: Computer pseudophakic eye models were implemented using reported post-LASIK corneal aberrations (refractive corrections from -7.5 to +4.5 diopters [D]) and virtually implanted with monofocal (AcrySof IQ) or EDOF (AcrySof IQ Vivity) IOLs. Retinal image quality was quantified through visual Strehl (VS). The depth of focus (DOF) was calculated from the through-focus VS curves. Halos were estimated from the light spread in the image of a pinhole. Those quantitative parameters were obtained for 5.0 and 3.0 mm pupil diameters. Results: Simulated virgin eyes showed VS of 0.89/0.99 with monofocal IOLs and 0.74/0.52 with EDOF IOLs for 5.0/3.0 mm pupils at best focus. VS decreased with induced spherical aberration (SA) by 25% and with induced SA + coma by 61% on average (3.0 mm pupils). The DOF was 2.50 D in virgin eyes with EDOF IOLs, 1.66 ± 0.30 and 2.54 ± 0.31 D ( P < .05) on average in post-LASIK eyes for 3.0 mm pupils, monofocal and EDOF IOLs, respectively. Halos were more sensitive to SA induction for 5.0 mm pupils, and induction of positive SA (myopic LASIK) resulted in reduced halos with the EDOF when compared with the monofocal IOLs, by 1.62 (SA) and 1.86 arc min (SA + coma), on average. Conclusions: Computer post-LASIK pseudophakic eye models showed that the DOF was less dependent on the presence of SA and coma with EDOF IOLs and that halos were reduced with EDOF IOLs compared with the monofocal IOL for a range of SA.
MeSH term(s)	Humans ; Keratomileusis, Laser In Situ ; Visual Acuity ; Coma ; Lenses, Intraocular ; Vision, Ocular ; Prosthesis Design
Language	English
Publishing date	2023-07-17
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	632744-8
ISSN	1873-4502 ; 0886-3350
ISSN (online)	1873-4502
ISSN	0886-3350
DOI	10.1097/j.jcrs.0000000000001260
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Article ; Online: Enzymatically mediated fluorescent copper nanocluster generation for tyramine determination.

Camacho-Aguayo, Javier / de Marcos, Susana / Pericás, Marta / Galbán, Javier

Analytical and bioanalytical chemistry

2023 Volume 415, Issue 11, Page(s) 2037–2044

Abstract: This work details the enzymatic generation of fluorescence nanomaterials and the use of this optical signal as the analytical parameter for the quantification of the substrate. More specifically, fluorescent copper nanoclusters have been obtained during ... ...

Abstract	This work details the enzymatic generation of fluorescence nanomaterials and the use of this optical signal as the analytical parameter for the quantification of the substrate. More specifically, fluorescent copper nanoclusters have been obtained during the enzymatic reaction of tyramine oxidase and tyramine in the presence of Cu(II); the fluorescence intensity being proportional to the concentration of tyramine. The nanoclusters obtained show fluorescence at 445 nm by being excited at 320 nm and have been characterized by TEM, EDX, and XPS. The formation mechanism has also been studied, suggesting that under the optimal conditions (0.1 M MES buffer and pH = 6), the formation of the nanoclusters is due to the reducing properties of the product of the enzymatic reaction (p-hydroxybenzaldehyde) in MES buffer. The method shows a linear relationship with the concentration of tyramine in the range from 1.0·10
MeSH term(s)	Metal Nanoparticles ; Copper/chemistry ; Fluorescent Dyes ; Spectrometry, Fluorescence/methods ; Tyramine/chemistry
Chemical Substances	Copper (789U1901C5) ; Fluorescent Dyes ; Tyramine (X8ZC7V0OX3)
Language	English
Publishing date	2023-02-10
Publishing country	Germany
Document type	Journal Article
ZDB-ID	201093-8
ISSN	1618-2650 ; 0016-1152 ; 0372-7920
ISSN (online)	1618-2650
ISSN	0016-1152 ; 0372-7920
DOI	10.1007/s00216-023-04571-4
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Article ; Online: In situ enzymatic generation of Au/Pt nanoparticles as an analytical photometric system: proof of concept determination of tyramine.

Camacho-Aguayo, Javier / de Marcos, Susana / Felices, Carlos / Galbán, Javier

Mikrochimica acta

2023 Volume 190, Issue 4, Page(s) 114

Abstract: In situ enzymatic generation of bimetallic nanoparticles, mainly Au/Pt, overcomes the drawbacks (continuous absorbance drift, modest LOQ, and long-time reaction) observed when AuNP alone are produced. In this study, Au/Pt nanoparticles have been ... ...

Abstract	In situ enzymatic generation of bimetallic nanoparticles, mainly Au/Pt, overcomes the drawbacks (continuous absorbance drift, modest LOQ, and long-time reaction) observed when AuNP alone are produced. In this study, Au/Pt nanoparticles have been characterized by EDS, XPS, and HRTEM images using the enzymatic determination of tyramine with tyramine oxidase (TAO) as a model. Under experimental conditions, the Au/Pt NPs show an absorption maximum at 580 nm which can be related to the concentration of tyramine in the range 1.0 × 10
Language	English
Publishing date	2023-03-06
Publishing country	Austria
Document type	Journal Article
ZDB-ID	89-9
ISSN	1436-5073 ; 0026-3672
ISSN (online)	1436-5073
ISSN	0026-3672
DOI	10.1007/s00604-023-05698-y
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Article ; Online: Gold nanoparticle formation as an indicator of enzymatic methods: colorimetric L-phenylalanine determination.

Martín-Barreiro, Alba / de Marcos, Susana / Galbán, Javier

Analytical and bioanalytical chemistry

2022 Volume 414, Issue 8, Page(s) 2641–2649

Abstract: An enzymatic-colorimetric method has been developed based on the reaction between L-phenylalanine (L-Phe) and the L-amino acid oxidase (LAAO) in the presence of Au(III), which has led to the formation of gold nanoparticles. The intensity of the localized ...

Abstract	An enzymatic-colorimetric method has been developed based on the reaction between L-phenylalanine (L-Phe) and the L-amino acid oxidase (LAAO) in the presence of Au(III), which has led to the formation of gold nanoparticles. The intensity of the localized surface plasmon resonance (LSPR) band of the generated nanoparticles (550 nm) can be related to the concentration of L-Phe in the sample. The mechanism of the LAAO-L-Phe enzyme reaction in the presence of Au(III) has been studied through the evaluation and optimization of experimental conditions. These studies have reinforced the hypothesis that the catalytic center of the enzyme helps the Au(III) reduction and, thanks to the protein, the Au
MeSH term(s)	Colorimetry/methods ; Gold/chemistry ; Limit of Detection ; Metal Nanoparticles/chemistry ; Phenylalanine ; Surface Plasmon Resonance/methods
Chemical Substances	Phenylalanine (47E5O17Y3R) ; Gold (7440-57-5)
Language	English
Publishing date	2022-01-21
Publishing country	Germany
Document type	Journal Article
ZDB-ID	201093-8
ISSN	1618-2650 ; 0016-1152 ; 0372-7920
ISSN (online)	1618-2650
ISSN	0016-1152 ; 0372-7920
DOI	10.1007/s00216-022-03900-3
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Article: Vision with spatial light modulator simulating multifocal contact lenses in an adaptive optics system.

Vedhakrishnan, Shrilekha / Vinas, Maria / Aissati, Sara / Marcos, Susana

Biomedical optics express

2021 Volume 12, Issue 5, Page(s) 2859–2872

Abstract: Visual simulators are useful tools to provide patients experience of multifocal vision prior to treatment. In this study, commercially available center-near aspheric multifocal contact lenses (MCLs) of low, medium, and high additions were mapped on a ... ...

Abstract	Visual simulators are useful tools to provide patients experience of multifocal vision prior to treatment. In this study, commercially available center-near aspheric multifocal contact lenses (MCLs) of low, medium, and high additions were mapped on a spatial light modulator (SLM) and validated on a bench. Through focus visual acuity (TFVA) was measured in subjects through the SLM and real MCLs on the eye. A correlation metric revealed statistically significant shape similarity between TFVA curves with real and simulated MCLs. A Bland-Altman analysis showed differences within confidence intervals of ±0.01 logMAR for LowAdd/MediumAdd and ±0.06 logMAR for HighAdd. Visual performance with simulated MCLs outperformed real MCLs by ∼20%. In conclusion, SLM captures the profile of center-near MCLs and reproduces vision with real MCLs, revealing that the MCL profile and its interactions with the eye's optics (and not fitting aspects) account for the majority of the contributions to visual performance with MCLs.
Language	English
Publishing date	2021-04-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	2572216-5
ISSN	2156-7085
ISSN	2156-7085
DOI	10.1364/BOE.419680
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Article ; Online: Monovision Correction Preference and Eye Dominance Measurements.

Rodriguez-Lopez, Victor / Barcala, Xoana / Zaytouny, Amal / Dorronsoro, Carlos / Peli, Eli / Marcos, Susana

Translational vision science & technology

2023 Volume 12, Issue 3, Page(s) 18

Abstract: Purpose: To propose new methods for eye selection in presbyopic monovision corrections.: Methods: Twenty subjects with presbyopia performed two standard methods of binary eye dominance identification (sensory with +1.50 diopters [D ]and +0.50 D and ... ...

Abstract	Purpose: To propose new methods for eye selection in presbyopic monovision corrections. Methods: Twenty subjects with presbyopia performed two standard methods of binary eye dominance identification (sensory with +1.50 diopters [D ]and +0.50 D and sighting with "hole-in-the-card") and two psychophysical methods of perceived visual quality: (1) the Preferential test, 26 natural images were judged with the near addition in one eye or in the other in a 2-interval forced-choice task, and the Eye Dominance Strength (EDS) defined as the proportion of trials where one monovision is preferred over the other; (2) the Multifocal Acceptance Score (MAS-2EV) test, the perceived quality of a natural images set (for 2 luminance levels and distances) was scored and EDS defined as the score difference between monovision in one eye or the other. Left-eye and right-eye dominance are indicated with negative and positive values, respectively. Tests were performed using a Simultaneous Vision Simulator, which allows rapid changes between corrections. Results: Standard sensory and sighting dominances matched in only 55% of subjects. The Preferential EDS (ranging from -0.7 to +0.9) and MAS-2EV EDS (ranging from -0.6 to +0.4) were highly correlated. Selecting the eye for far in monovision with the MAS-2EV, sensory, or sighting tests would have resulted in 79%, 64%, and 43% success considering the Preferential test as the gold standard. Conclusions: Tests based on perceptual preference allow selection of the preferred monovision correction and measurement of dominance strength. Translational relevance: The binocular visual simulator allows efficient implementation of eye preference tests for monovision in clinical use.
MeSH term(s)	Humans ; Vision, Monocular ; Visual Acuity ; Dominance, Ocular ; Vision, Ocular ; Vision Tests
Language	English
Publishing date	2023-01-29
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	2674602-5
ISSN	2164-2591 ; 2164-2591
ISSN (online)	2164-2591
ISSN	2164-2591
DOI	10.1167/tvst.12.3.18
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