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Article ; Online: Hepatitis B prevalence in Brazilian waste pickers

Gabriel Souza-Silva / Marcos Paulo Gomes Mol

Revista de Saúde Pública, Vol

a systematic review with meta-analysis

2021 Volume 55

Abstract: ABSTRACT OBJECTIVE: To describe the hepatitis B prevalence in Brazilian waste pickers. METHODS: We performed a literature search in the SciELO, Biblioteca Virtual em Saúde (BVS), PubMed and Web of Science databases using the descriptors: “hepatitis B” ... ...

Abstract	ABSTRACT OBJECTIVE: To describe the hepatitis B prevalence in Brazilian waste pickers. METHODS: We performed a literature search in the SciELO, Biblioteca Virtual em Saúde (BVS), PubMed and Web of Science databases using the descriptors: “hepatitis B” AND (“informal recycling” OR “waste picker” OR “recyclable waste collectors” OR “solid waste segregator”) AND (“recyclable waste” OR “solid waste”) AND Brazil. Epidemiological studies on HBV in Brazilian waste pickers published prior to February 2020 were included and evaluated for quality and bias using a funnel plot. RESULTS: This meta-analysis consisted of five articles. Prevalence of HBV surface antigen seropositivity was 14% (95%CI: 6%–22%) in Brazilian waste pickers. CONCLUSION: HBV prevalence in Brazilian waste pickers remains high. There should be more campaigns showing the importance of vaccination and personal protective equipment use.
Keywords	Solid Waste Segregators ; Hepatitis B ; epidemiology ; Systematic Review ; Public aspects of medicine ; RA1-1270
Subject code	710
Language	English
Publishing date	2021-11-01T00:00:00Z
Publisher	Universidade de São Paulo
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Água e Resíduos Sólidos

Valdir Lamim-Guedes / Marcos Paulo Gomes Mol

Fronteiras: Journal of Social, Technological and Environmental Science, Vol 7, Iss 2, Pp 140-

Ambiente, Saúde e Bem-Estar Humano no Contexto do Antropoceno

2018 Volume 164

Abstract: O Antropoceno permite percebermos a influência humana no planeta e indica a necessidade de tomar atitudes reais em prol de questões socioambientais, como o acesso à água, que envolve a disponibilidade física e fatores condicionantes de origem política, ... ...

Abstract	O Antropoceno permite percebermos a influência humana no planeta e indica a necessidade de tomar atitudes reais em prol de questões socioambientais, como o acesso à água, que envolve a disponibilidade física e fatores condicionantes de origem política, econômica ou social. Neste texto, trataremos do acesso à água e como este é determinante para a saúde e bem-estar, dependendo da conservação ambiental. Dois desafios - refugiados climáticos e aprendizagem social - serão apresentados como questões relevantes para a discussão sobre o planejamento de consumo de água em longo prazo. Pretendemos demonstrar que a participação, corresponsabilidade e diálogo são essenciais para que as arenas já construídas, como os Comitês de Bacia Hidrográficas, sejam de fato plenários de discussão e ambiente propício para uma gestão hídrica para um melhor compartilhamento deste recurso limitado.
Keywords	Recursos Hídricos ; Comitê de Bacia Hidrográfica ; Gestão Hídrica ; Questões Socioambientais ; Environmental sciences ; GE1-350 ; Science ; Q
Language	Portuguese
Publishing date	2018-08-01T00:00:00Z
Publisher	Centro Universitário de Anápolis
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Low eligibility for hepatitis B treatment in the Brazilian public health system

Cristiane Faria Oliveira Scarponi / Marco Antônio Ferreira Pedrosa / Marcos Paulo Gomes Mol / Michael John Mascarenhas Hardman / Dirceu Bartolomeu Greco

Revista da Sociedade Brasileira de Medicina Tropical, Vol

2022 Volume 55

Abstract: ABSTRACT Background: Chronic hepatitis B (CHB) affects 257 million people worldwide. However, the proportion of patients eligible for treatment in the public health system has not been established. This study describes the clinical and laboratory ... ...

Abstract	ABSTRACT Background: Chronic hepatitis B (CHB) affects 257 million people worldwide. However, the proportion of patients eligible for treatment in the public health system has not been established. This study describes the clinical and laboratory profiles of untreated CHB patients and estimates the eligibility rate for antiviral therapy in accordance with the Brazilian Clinical Protocol and Therapeutic Guidelines. Methods: Records of 670 CHB patients were collected from May 2012 to September 2013 in Minas Gerais. Data from each patient were analyzed by hepatitis B virus (HBV) management. Results: 461 CHB patients were treatment-naive. Of these, 23 were HBeAg-positive, 352 were HBeAg-negative, and 14 were clinically diagnosed with cirrhosis. Periodic monitoring was performed in only three patients. However, 9.3% of untreated patients met the eligibility criteria for HBV treatment. Conclusions: Few CHB patients were active carriers and eligible candidates for antiviral therapy. This study revealed inadequate pre-treatment conduct in the Brazilian public health system, emphasizing the need for regular laboratory follow-up for patients initially not eligible for treatment. Such information may indirectly subsidize the planning and improvement of actions and services related to optimal HBV management in the public sphere.
Keywords	Hepatitis B ; Treatment eligibility ; Guideline adherence ; Antiviral therapy ; Public health ; Brazil ; Arctic medicine. Tropical medicine ; RC955-962
Subject code	610
Language	English
Publishing date	2022-04-01T00:00:00Z
Publisher	Sociedade Brasileira de Medicina Tropical (SBMT)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Theoretical environmental risk assessment of ten used pharmaceuticals in Belo Horizonte, Brazil

Neves, Arthur Couto / Marcos Paulo Gomes Mol

Environmental monitoring and assessment. 2019 May, v. 191, no. 5

2019

Abstract: An evaluation of the environmental risk assessment (ERA) proposed by European Medicines Agency (EMA) and its applicability in Brazil was performed on ten of Belo Horizonte’s most pharmaceuticals by the Brazilian National Health Service (SUS). The ... ...

Abstract	An evaluation of the environmental risk assessment (ERA) proposed by European Medicines Agency (EMA) and its applicability in Brazil was performed on ten of Belo Horizonte’s most pharmaceuticals by the Brazilian National Health Service (SUS). The predicted environmental concentrations (PECs) was proposed, with some refinements to a better representation of the city of study. All PECs obtained were compared only to measured environmental concentrations around the world, due to the lack available data in the city of study and in Brazil. During the performance of EMA’s guideline, the risk quotient (RQ) of impact was established through the ratio of PECs and predicted no-effect concentrations (PNECs). The PECs obtained in more refined phases show the initial evaluation of EMA’s guideline, possible subdimensions, and the potential risks. The RQ for all studied pharmaceuticals ranges from clonazepam (1.26) to losartan (5457.45). These results indicate potential risks to the aquatic life present in the streams that receive the wastewater treatment plant’s effluent. This risk can be spread since the streams carry these contaminants to other water bodies that undergo to multiple cities of Brazil, and even after dilutions, it can still be potentially toxic to the biotic life. ERA shows that it can be a useful tool for a better understanding and modeling of pharmaceuticals fate in the environment, specifically in water bodies. In addition, the usage of this model shows to be a useful tool that determines which contaminant should follow a more thorough study since the detection and analysis of pharmaceuticals in environmental samples are costly and technically challenging.
Keywords	aquatic organisms ; cities ; drugs ; environmental assessment ; guidelines ; health services ; models ; risk ; risk assessment ; streams ; surface water ; toxicity ; wastewater treatment ; Brazil
Language	English
Dates of publication	2019-05
Size	p. 275.
Publishing place	Springer International Publishing
Document type	Article
ZDB-ID	782621-7
ISSN	1573-2959 ; 0167-6369
ISSN (online)	1573-2959
ISSN	0167-6369
DOI	10.1007/s10661-019-7386-3
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Gestão adequada de resíduos sólidos como fator de proteção na ocorrência da dengue

Marcos Paulo Gomes Mol / Josiane T. Matos Queiroz / Júlia Gomes / Léo Heller

Revista Panamericana de Salud Pública, Vol 44, Iss 22, Pp 1-

2020 Volume 9

Abstract: Objetivo. Verificar a existência de associação de indicadores de gestão de resíduos sólidos e socioeconômicos municipais com índices de incidência de dengue, Zika e Chikungunya nos municípios do estado brasileiro de Minas Gerais. Métodos. Este estudo de ... ...

Abstract	Objetivo. Verificar a existência de associação de indicadores de gestão de resíduos sólidos e socioeconômicos municipais com índices de incidência de dengue, Zika e Chikungunya nos municípios do estado brasileiro de Minas Gerais. Métodos. Este estudo de caráter exploratório, quantitativo e transversal abrangeu os 853 municípios do estado de Minas Gerais. Todos os dados utilizados foram secundários, coletados e agrupados por regionais de planejamento. Como variáveis independentes, foram consideradas a cobertura de coleta de resíduos sólidos urbanos, cobertura de coleta seletiva e massa de resíduos sólidos urbanos, além de um indicador da qualidade da destinação final de resídulos, índices de desenvolvimento humano municipal e de Gini, renda mensal per capita e porcentagem de vulneráveis à pobreza. Os fatores potencialmente associados aos desfechos incidências municipais de dengue, Chikungunya e Zika foram selecionados inicialmente através de análises univariadas. Posteriormente, os modelos de regressão linear para as incidências de dengue, Chikungunya ou Zika foram gerados considerando os preditores selecionados pela análise univariada. Resultados. Não foi observada associação entre gestão de resíduos sólidos e incidência de Chikungunya e Zika. Por sua vez, a incidência de dengue associou-se à gestão de resíduos sólidos e apresentou relação inversa significativa com o percentual de vulneráveis à pobreza. Houve também associação direta o índice de Gini, sugerindo que quanto maiores os registros de incidência de dengue de 2007 a 2016, maiores os valores de Gini dos municípios ou seja, maior a desigualdade social. A cobertura da coleta seletiva apresentou relação inversa e significativa com os casos de dengue, sugerindo que quanto menor a cobertura da coleta de seletiva, maiores foram os casos registrados de dengue. Conclusões. A gestão de resíduos sólidos pode influenciar os casos de dengue e, por isso, deve ser considerada nas ações de saúde pública.
Keywords	dengue ; vírus zika ; vírus chikungunya ; resíduos sólidos ; brasil ; Medicine ; R ; Arctic medicine. Tropical medicine ; RC955-962 ; Public aspects of medicine ; RA1-1270
Language	English
Publishing date	2020-04-01T00:00:00Z
Publisher	Pan American Health Organization
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Hepatitis B and C in household and health services solid waste workers

Marcos Paulo Gomes Mol / Dirceu Bartolomeu Greco / Sandy Cairncross / Leo Heller

Cadernos de Saúde Pública, Vol 31, Iss suppl 1, Pp 295-

2015 Volume 300

Abstract: Abstract Human contact with solid waste poses biological, chemical, and physical health risks for workers involved in waste collection, transportation, and storage. The potential risk to human health resulting from contact with health services waste or ... ...

Abstract	Abstract Human contact with solid waste poses biological, chemical, and physical health risks for workers involved in waste collection, transportation, and storage. The potential risk to human health resulting from contact with health services waste or household waste still sparks considerable controversy. The aim of this study was to identify the context of scientific discussions on risk/infection from the hepatitis B and C viruses in workers that collect solid waste from health services or households. The search covered publications up to 2013 in Brazilian and international databases, and 11 articles were selected through a literature review. Of these, six conclude that there is an increased risk of infection in workers that collect household waste when compared to those unexposed to waste, three point to greater risk for workers that collect health services waste as compared to those that collect ordinary waste, and the other two found no difference between exposed and unexposed individuals.
Keywords	Residuos Sólidos ; Hepatitis B ; Hepatitis C ; Salud Urbana ; Public aspects of medicine ; RA1-1270 ; Medicine ; R
Subject code	360
Language	English
Publishing date	2015-11-01T00:00:00Z
Publisher	Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Cleaner production at pharmaceutical industry

Edilaine Conceição Rezende / Marcos Paulo Gomes Mol / Aline Aparecida Thomaz Pereira

Revista Metropolitana de Sustentabilidade, Vol 5, Iss 3, Pp 131-

first steps assessment

2015 Volume 145

Abstract: The Cleaner Production (CP) is an environmental management system effective to comply the environmental obligations and promote sustainable development of enterprises. In this study, the implementing possibilities of CP practices were evaluated to ... ...

Abstract	The Cleaner Production (CP) is an environmental management system effective to comply the environmental obligations and promote sustainable development of enterprises. In this study, the implementing possibilities of CP practices were evaluated to pharmaceutical industry, through prior identification procedures for Pharmaceutical Manufacturing Practices. The study was conducted in a scientific and health care institution, which produces pharmaceutical drugs and makes assistance for public health. The production process was evaluated and made a survey of the main points of waste and sewage generations in each stage, in order to diagnose the measures of CP established and propose new actions. Thus, by using this tool, it was possible to demonstrate the reduction of environmental impacts associated with pharmaceutical production. The Pharmaceutical Manufacturing Practices also contributed to the implementation of measures CP, preserving the final product quality, and generating environmental and economic benefits.
Keywords	Aspectos e impactos ambientais ; Indústria farmacêutica ; Produção mais limpa ; Geography. Anthropology. Recreation ; G ; Environmental sciences ; GE1-350
Subject code	660
Language	Portuguese
Publishing date	2015-12-01T00:00:00Z
Publisher	Faculdades Metropolitanas Unidas
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Hepatitis Delta Prevalence in South America

Cristiane Faria de Oliveira Scarponi / Raquel Duarte Nunes da Silva / Job Alves de Souza Filho / Maria Regina Lage Guerra / Marco Antônio Ferreira Pedrosa / Marcos Paulo Gomes Mol

Revista da Sociedade Brasileira de Medicina Tropical, Vol 52, Iss

A Systematic Review and Meta-Analysis

2019

Abstract: Abstract Hepatitis delta virus (HDV) has been associated with acute or chronic hepatitis in Latin America, but there is no prevalence study covering South American countries. This meta-analysis aimed to estimate anti-HDV prevalence through a systematic ... ...

Abstract	Abstract Hepatitis delta virus (HDV) has been associated with acute or chronic hepatitis in Latin America, but there is no prevalence study covering South American countries. This meta-analysis aimed to estimate anti-HDV prevalence through a systematic review of published articles in English, Portuguese and Spanish until December 2017. Searches were conducted in Health Virtual Library, Capes, Lilacs, PubMed, and SciELO, according to defined criteria regarding participant selection and geographical setting. Study quality was assessed using the GRADE guidelines. Pooled anti-HDV prevalence was calculated using the DerSimonian-Laird random-effects model with Freeman-Tukey double arcsine transformation. Out of the 405 identified articles, only 31 met the eligibility criteria for inclusion in the meta-analysis. In South America, pooled anti-HDV prevalence among hepatitis B virus carriers was 22.37% (95% confidence interval: 13.72-32.26), though it appeared less frequently in some countries and populations, according to the data collection date. The findings indicated significant successive reductions in anti-HDV prevalence over thirty years. However, there was a scarcity of HDV epidemiological studies outside the Amazon Basin, notably in the Southwest continent and absence of target population standardization. There was a high HDV prevalence in South American countries, despite differences in methodological characteristics and outcomes, highlighting a drastic decline in the last decades. Future studies should identify HDV prevalence estimates in other regions of the continent and identify risk factors.
Keywords	Hepatitis delta virus ; Anti-HDV ; Prevalence ; South America ; Epidemiology ; Arctic medicine. Tropical medicine ; RC955-962
Subject code	306
Language	English
Publishing date	2019-01-01T00:00:00Z
Publisher	Sociedade Brasileira de Medicina Tropical (SBMT)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Are waste pickers at risk for hepatitis B and C infections because of poverty or environmental exposures?

Cristiane Faria de Oliveira Scarponi / Tara Rava Zolnikov / Marcos Paulo Gomes Mol

Revista da Sociedade Brasileira de Medicina Tropical, Vol 52

Keywords	Arctic medicine. Tropical medicine ; RC955-962
Language	English
Publisher	Sociedade Brasileira de Medicina Tropical (SBMT)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Is waste collection associated with hepatitis B infection? A meta-analysis

Marcos Paulo Gomes Mol / Sandy Cairncross / Dirceu Bartolomeu Greco / Leo Heller

Revista da Sociedade Brasileira de Medicina Tropical, Vol 50, Iss 6, Pp 756-763

Abstract: Abstract This meta-analysis, which is based on a previously published systematic review, aims to contribute to the scientific discussion on hepatitis B virus (HBV) infection in workers who are exposed to domestic and healthcare wastes. Publications were ... ...

Abstract	Abstract This meta-analysis, which is based on a previously published systematic review, aims to contribute to the scientific discussion on hepatitis B virus (HBV) infection in workers who are exposed to domestic and healthcare wastes. Publications were sought which had been made available on the data used by December 2013 and updated to December 2016. The quality of the included studies was assessed according to the guidelines of Loney et al. for the critical appraisal of studies on the prevalence or incidence of a health problem. To verify the presence of heterogeneity between the papers, we used the Chi-squared test based on a Q statistic. A funnel plot was used to test for publication bias. All included studies had across-sectional study design. The association between exposure to waste and positive serology for the HBV surface antigen (HBsAg) showed a significant association [odds ratio (OR) 1.89, 95% confidence interval (CI) 1.27-2.86; p = 0.0019]. The prevalence rates of HBsAg and anti-HBc seropositivity was 0.04 (95% CI 0.03-0.05) and 0.21 (95% CI 0.14-0.28), respectively (p <0.0001). We found no evidence of publication bias. The results of this meta-analysis indicate a statistically significant association between exposure to solid waste, whether healthcare or domestic, and positive HBV infection markers. Therefore, the working conditions of waste collectors should be analyzed more closely. Immunization against HBV is recommended as the chief preventive measure for all solid waste workers.
Keywords	Meta-analysis ; Hepatitis B ; Waste workers ; Domestic waste ; Healthcare waste ; Arctic medicine. Tropical medicine ; RC955-962
Subject code	690
Language	English
Publisher	Sociedade Brasileira de Medicina Tropical (SBMT)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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