Article ; Online: High-flow nasal oxygenation or standard oxygenation for gastrointestinal endoscopy with sedation in patients at risk of hypoxaemia: a multicentre randomised controlled trial (ODEPHI trial).
British journal of anaesthesia
2021 Volume 127, Issue 1, Page(s) 133–142
Abstract: Background: We aimed to determine whether high-flow nasal oxygen could reduce the incidence of decreased peripheral oxygen saturation (SpO: Methods: This was a multicentre, randomised controlled trial with blinded assessment of the primary outcome ... ...
| Abstract | Background: We aimed to determine whether high-flow nasal oxygen could reduce the incidence of decreased peripheral oxygen saturation (SpO Methods: This was a multicentre, randomised controlled trial with blinded assessment of the primary outcome evaluating high-flow nasal oxygen (gas flow 70 L min Results: In 379 patients, a decrease in SpO Conclusions: In patients at risk of hypoxaemia undergoing gastrointestinal endoscopy under deep sedation, use of high-flow nasal oxygen significantly reduced the incidence of peripheral oxygen desaturation. Clinical trial registration: NCT03829293. |
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| MeSH term(s) | Aged ; Cannula ; Endoscopy, Gastrointestinal/adverse effects ; Endoscopy, Gastrointestinal/methods ; Female ; Humans ; Hypnotics and Sedatives/administration & dosage ; Hypnotics and Sedatives/adverse effects ; Hypoxia/diagnosis ; Hypoxia/etiology ; Hypoxia/prevention & control ; Male ; Middle Aged ; Oxygen Inhalation Therapy/instrumentation ; Oxygen Inhalation Therapy/methods ; Risk Factors ; Single-Blind Method | |||||
| Chemical Substances | Hypnotics and Sedatives | |||||
| Language | English | |||||
| Publishing date | 2021-04-28 | |||||
| Publishing country | England | |||||
| Document type | Journal Article ; Multicenter Study ; Randomized Controlled Trial | |||||
| ZDB-ID | 80074-0 | |||||
| ISSN | 1471-6771 ; 0007-0912 | |||||
| ISSN (online) | 1471-6771 | |||||
| ISSN | 0007-0912 | |||||
| DOI | 10.1016/j.bja.2021.03.020 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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