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  1. Article ; Online: Lateral pterygoid muscle ultrasound-guided injection: A technical note.

    Rodríguez-Gimillo, Pablo / Valverde-Navarro, Alfonso / Margaix-Muñoz, Maria / Poveda-Roda, Rafael / Delgado-Navarro, Carlos / Puig-Bernabeu, Jaume

    Journal of stomatology, oral and maxillofacial surgery

    2023  , Page(s) 101547

    Abstract: Background: Temporomandibular disorders (TMDs) are a frequent cause of orofacial pain, causing functional disability and a negative impact on quality of life. Botulinum toxin (BTX-A) injection in lateral pterygoid muscle (LPM) is one of the treatment ... ...

    Abstract Background: Temporomandibular disorders (TMDs) are a frequent cause of orofacial pain, causing functional disability and a negative impact on quality of life. Botulinum toxin (BTX-A) injection in lateral pterygoid muscle (LPM) is one of the treatment modalities proposed, but the blind puncture guided by EMG carries a risk of vascular puncture or diffusion of the toxin to nearby muscles. We describe an ultrasound-guided approach and evaluate the spread of the injection in a fresh human cadaver.
    Methods: A fresh human cadaver was injected. An out-of-plane approach was performed using a convex probe, injecting 1.0 ml of 0.25% methylene blue dye into the LPM. After, a dissection was performed to isolate the lateral pterygoid muscle and assess the spread of the dye.
    Results: Ultrasound-guided injection allowed to visualize in real-time the spread of the dye within the LPM. The deep and superficial muscles nearby to LPM were not stained by the dye, but upper and lower head of LPM was heavily stained.
    Conclusion: Ultrasound-guided approach for the injection of BTX-A into the LPM could be considered a successful and safe treatment for myofascial pain related to TMD. Therefore, further clinical studies are needed to study the reproducibility of ultrasound guided LPM injection and to evaluate the clinical results.
    Language English
    Publishing date 2023-06-30
    Publishing country France
    Document type Journal Article
    ZDB-ID 2916276-2
    ISSN 2468-7855 ; 2468-8509
    ISSN (online) 2468-7855
    ISSN 2468-8509
    DOI 10.1016/j.jormas.2023.101547
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Ewing sarcoma of the oral cavity. A review.

    Margaix-Muñoz, Maria / Bagán, José / Poveda-Roda, Rafael

    Journal of clinical and experimental dentistry

    2017  Volume 9, Issue 2, Page(s) e294–e301

    Abstract: Objectives: A review is made of the clinical, diagnostic, therapeutic and survival characteristics of Ewing sarcoma (ES) of the oral cavity.: Material and methods: A systematic literature search was carried out, with restrictions referred to time ( ... ...

    Abstract Objectives: A review is made of the clinical, diagnostic, therapeutic and survival characteristics of Ewing sarcoma (ES) of the oral cavity.
    Material and methods: A systematic literature search was carried out, with restrictions referred to time (1960-2014), language (English and Spanish) and type of study (case reports, letters, datasets, reviews). The following MeSH terms and boolean operators were used: Ewing AND Sarcoma AND [tongue, jaw, maxilla, cheek, condyle OR temporomandibular, floor AND mouth, gum OR gingiva, palate OR palatal, lip, uvula, head AND neck].
    Results: Seventy-one cases of ES of the oral cavity were documented from 53 articles. The main differences versus ES of other locations were a younger age at manifestation, a shorter time from symptoms onset to diagnosis, and swelling as the most frequent clinical manifestation versus swelling and pain in the rest of disease locations. The way in which ES manifests in the oral cavity is varied and comprises dental displacement (19.7%), dental mobility (7%), root reabsorption (5.6%), destruction of the dental follicle (4.2%), premature exfoliation (4.2%) and paresthesia of the chin (2.8%). Metastatic neck adenopathies appear in 11.3% of the cases. Significant differences in survival are observed between patients with a complete diagnosis of ES (hematoxylin-eosin staining, PAS positivity, CD99 positivity) and those with an incomplete diagnosis.
    Conclusions: Ewing sarcoma of the oral cavity presents a series of specific features that distinguish it from ES of other locations.
    Language English
    Publishing date 2017-02-01
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 2586647-3
    ISSN 1989-5488
    ISSN 1989-5488
    DOI 10.4317/jced.53575
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Intravenous bisphosphonate-related osteonecrosis of the jaws: influence of coadjuvant antineoplastic treatment and study of buccodental condition.

    Margaix-Muñoz, Maria / Bagan, José / Poveda-Roda, Rafael

    Medicina oral, patologia oral y cirugia bucal

    2013  Volume 18, Issue 2, Page(s) e194–200

    Abstract: Objectives: To determine whether coadjuvant antineoplastic treatment can influence the number and size of bone exposures among patients with intravenous bisphosphonate-related osteonecrosis of the jaws (iBRONJ), and to analyze the buccodental condition ... ...

    Abstract Objectives: To determine whether coadjuvant antineoplastic treatment can influence the number and size of bone exposures among patients with intravenous bisphosphonate-related osteonecrosis of the jaws (iBRONJ), and to analyze the buccodental condition of these patients.
    Material and methods: The study sample comprised 67 patients with iBRONJ, 53 patients without iBRONJ receiving treatment with intravenous bisphosphonates, and 36 healthy subjects. In all three groups, measurements were made of the CAO index and of resting whole saliva and stimulated whole saliva. In the patients with iBRONJ, the size (cm) and number of bone exposures were recorded. The data obtained were subjected to analysis of variance (ANOVA), the Mann-Whitney U-test, and multivariate logistic regression analysis.
    Results: A total of 57.6% of the patients presented single bone exposure, 25.4% presented two, and 17% more than two exposures. The mean exposure size was 2.3 ± 1.9 cm. Neither the bivariate analysis nor the multivariate multiple regression analysis found coadjuvant antineoplastic treatment to exert a statistically significant effect upon the number and size of bone exposures. On the other hand, there were statistically significant differences among the three study groups in relation to the CAO index (p=0.02) and the number of missing teeth (p=0.00). The resting whole saliva and stimulated whole saliva levels were similar in the three groups, though the patients with osteonecrosis of the jaws showed comparatively lower SWS levels.
    Conclusions: Coadjuvant antineoplastic treatment alone appears to exert no influence upon the size and number of bone exposures in iBRONJ. The patients with this disease show a higher CAO index and a larger number of missing teeth.
    MeSH term(s) Antineoplastic Agents/adverse effects ; Bisphosphonate-Associated Osteonecrosis of the Jaw ; Chemotherapy, Adjuvant ; Diphosphonates/administration & dosage ; Diphosphonates/adverse effects ; Female ; Humans ; Injections, Intravenous ; Male ; Middle Aged ; Mouth Diseases/chemically induced
    Chemical Substances Antineoplastic Agents ; Diphosphonates
    Language English
    Publishing date 2013-03-01
    Publishing country Spain
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2171573-7
    ISSN 1698-6946 ; 1698-4447
    ISSN (online) 1698-6946
    ISSN 1698-4447
    DOI 10.4317/medoral.18604
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5809: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Graft-versus-host disease affecting oral cavity. A review.

    Margaix-Muñoz, Maria / Bagán, José V / Jiménez, Yolanda / Sarrión, María-Gracia / Poveda-Roda, Rafael

    Journal of clinical and experimental dentistry

    2015  Volume 7, Issue 1, Page(s) e138–45

    Abstract: Graft versus host disease (GVHD) is one of the most frequent and serious complications of hematopoietic stem cell transplantation, and is regarded as the leading cause of late mortality unrelated to the underlying malignant disease. GVHD is an autoimmune ...

    Abstract Graft versus host disease (GVHD) is one of the most frequent and serious complications of hematopoietic stem cell transplantation, and is regarded as the leading cause of late mortality unrelated to the underlying malignant disease. GVHD is an autoimmune and alloimmune disorder that usually affects multiple organs and tissues, and exhibits a variable clinical course. It can manifest in either acute or chronic form. The acute presentation of GVHD is potentially fatal and typically affects the skin, gastrointestinal tract and liver. The chronic form is characterized by the involvement of a number of organs, including the oral cavity. Indeed, the oral cavity may be the only affected location in chronic GVHD. The clinical manifestations of chronic oral GVHD comprise lichenoid lesions, hyperkeratotic plaques and limited oral aperture secondary to sclerosis. The oral condition is usually mild, though moderate to severe erosive and ulcerated lesions may also be seen. The diagnosis is established from the clinical characteristics, though confirmation through biopsy study is sometimes needed. Local corticosteroids are the treatment of choice, offering overall response rates of close to 50%. Extracorporeal photopheresis and systemic corticosteroids in turn constitute second line treatment. Oral chronic GVHD is not considered a determinant factor for patient survival, which is close to 52% five years after diagnosis of the condition. Key words:Chronic graft-versus-host disease, oral chronic graft-versus-host disease, pathogenics, management, survival.
    Language English
    Publishing date 2015-02-01
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 2586647-3
    ISSN 1989-5488
    ISSN 1989-5488
    DOI 10.4317/jced.51975
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Sjögren's syndrome of the oral cavity. Review and update.

    Margaix-Muñoz, Maria / Bagán, José V / Poveda, Rafael / Jiménez, Yolanda / Sarrión, Gracia

    Medicina oral, patologia oral y cirugia bucal

    2009  Volume 14, Issue 7, Page(s) E325–30

    Abstract: Sjögren's syndrome is one of the most frequent autoimmune diseases. It is a chronic and systemic disorder predominantly found in women, and is characterized by the appearance of a lymphocytic inflammatory infiltrate, with dryness of the oral cavity and ... ...

    Abstract Sjögren's syndrome is one of the most frequent autoimmune diseases. It is a chronic and systemic disorder predominantly found in women, and is characterized by the appearance of a lymphocytic inflammatory infiltrate, with dryness of the oral cavity and eyes, secondary to involvement of the salivary and lacrimal glands. The underlying causal mechanism involves a number of factors and has not been clearly established, though an autoimmune response is known to be triggered, with the accumulation of immune complexes in the gland acini that interfere with gland function. In the oral cavity, xerostomia or hyposialia is the most disabling manifestation for patients, and is accompanied by rapidly progressing caries, candidiasis and an important worsening of buccodental health. The most important complication is a 44-fold increase in the risk of developing non-Hodgkin lymphoma, compared with the general population. The treatment of Sjögren's syndrome is limited to symptomatic management, and involves the use of solutions to replace salivary secretion and afford a measure of hydration, cholinergic agents such as pilocarpine to stimulate the unaffected gland tissue and, recently, the administration of substances that act against surface antigens of the B lymphocytes, such as anti-CD20 and anti-CD22 antibodies. The present study provides an update on this disease, placing special emphasis on its odontologic implications.
    MeSH term(s) Humans ; Mouth Diseases/diagnosis ; Mouth Diseases/therapy ; Sjogren's Syndrome/diagnosis ; Sjogren's Syndrome/therapy
    Language English
    Publishing date 2009-07-01
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 2171573-7
    ISSN 1698-6946 ; 1698-4447
    ISSN (online) 1698-6946
    ISSN 1698-4447
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5809: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Cardiovascular diseases in dental practice. Practical considerations.

    Margaix Muñoz, María / Jiménez Soriano, Yolanda / Poveda Roda, Rafael / Sarrión, Gracia

    Medicina oral, patologia oral y cirugia bucal

    2008  Volume 13, Issue 5, Page(s) E296–302

    Abstract: Coronary heart disease is the principal cause of death in the industrialized world. Its most serious expression, acute myocardial infarction, causes 7.2 million deaths each year worldwide, and it is estimated that 20% of all people will suffer heart ... ...

    Abstract Coronary heart disease is the principal cause of death in the industrialized world. Its most serious expression, acute myocardial infarction, causes 7.2 million deaths each year worldwide, and it is estimated that 20% of all people will suffer heart failure in the course of their lifetime. The control of risk cardiovascular factors, including arterial hypertension, obesity and diabetes mellitus is the best way to prevent such diseases. The most frequent and serious cardiovascular emergencies that can manifest during dental treatment are chest pain (as a symptom of underlying disease) and acute lung edema. Due to the high prevalence and seriousness of these problems, the dental surgeon must be aware of them and should be able to act quickly and effectively in the case of an acute cardiovascular event. In patients with a history of cardiovascular disease, attention must center on the control of pain, the reduction of stress, and the use or avoidance of a vasoconstrictor in dental anesthesia. In turn, caution is required in relation to the antiplatelet, anticoagulant and antihypertensive medication typically used by such patients.
    MeSH term(s) Heart Failure/complications ; Humans ; Mouth Diseases/complications ; Mouth Diseases/surgery ; Myocardial Ischemia/complications ; Oral Surgical Procedures ; Risk Factors
    Language English
    Publishing date 2008-05-01
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 2171573-7
    ISSN 1698-6946 ; 1698-4447
    ISSN (online) 1698-6946
    ISSN 1698-4447
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5809: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Changes in smoking habit among patients with a history of oral squamous cell carcinoma (OSCC).

    Poveda-Roda, Rafael / Bagán, José V / Jiménez-Soriano, Yolanda / Margaix-Muñoz, Maria / Sarrión-Pérez, Gracia

    Medicina oral, patologia oral y cirugia bucal

    2010  Volume 15, Issue 5, Page(s) e721–6

    Abstract: Objective: To determine the changes in smoking habit among patients with oral squamous cell carcinoma (OSCC) diagnosed and treated in the Service of Stomatology (Valencia University General Hospital. Valencia, Spain).: Material and methods: The study ...

    Abstract Objective: To determine the changes in smoking habit among patients with oral squamous cell carcinoma (OSCC) diagnosed and treated in the Service of Stomatology (Valencia University General Hospital. Valencia, Spain).
    Material and methods: The study involved 123 patients with a history of OSCC interviewed by telephone on their smoking habits at the time of the diagnosis and modifications in habits subsequently. The mean age at diagnosis was 60 years and 9 months (standard deviation, SD +/- 12 years and 2 months). Males predominated (61.8%) over females (38.2%). The mean time from the diagnosis of OSCC to the survey was 4 years and 6 months (SD +/- 3 years and 6 months).
    Results: Almost one-half of the patients (45.5%) were active smokers at the time of the diagnosis, with a mean duration of the habit of 34.9 years (SD +/- 12 years and 7 months). In turn, 19.5% of the patients were ex-smokers at diagnosis, with an average of 13 years and 9 months (SD +/- 9 years and 4 months) from smoking cessation to the development of cancer. A total of 57.1% of the smokers abandoned the habit at diagnosis, 8.9% continued to smoke to the same extent as before, and 33.9% reduced smoking.
    Conclusion: A full 44.4 % of our patients diagnosed with OSCC continued to smoke despite warnings of the risks, and although the majority claimed to have reduced their smoking habit, interventional strategies would be indicated to help ensure complete smoking cessation.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Carcinoma, Squamous Cell/complications ; Female ; Humans ; Male ; Middle Aged ; Mouth Neoplasms/complications ; Smoking/epidemiology ; Smoking Prevention
    Language English
    Publishing date 2010-09-01
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 2171573-7
    ISSN 1698-6946 ; 1698-4447
    ISSN (online) 1698-6946
    ISSN 1698-4447
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5809: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Bacteremia originating in the oral cavity. A review.

    Poveda-Roda, Rafael / Jiménez, Yolanda / Carbonell, Enrique / Gavaldá, Carmen / Margaix-Muñoz, María Margaix / Sarrión-Pérez, Gracia

    Medicina oral, patologia oral y cirugia bucal

    2008  Volume 13, Issue 6, Page(s) E355–62

    Abstract: In patients at risk because of heart disease, bacteremias induced by invasive dental treatments have been reported as a cause of bacterial endocarditis (BE) - a serious disorder that continues to involve a high mortality. As a result, different ... ...

    Abstract In patients at risk because of heart disease, bacteremias induced by invasive dental treatments have been reported as a cause of bacterial endocarditis (BE) - a serious disorder that continues to involve a high mortality. As a result, different scientific societies have supported recommendations for the administration of antibiotics prior to invasive dental treatments, in order to neutralize bacteremia. In this context, the recommendations of the American Heart Association (AHA) are the most widely used in our setting. Advances in our knowledge of the etiopathogenesis of bacterial endocarditis have placed increasingly less importance on invasive dental treatments as a causal factor (the AHA again reduced the number of cases in which antibiotic prophylaxis is recommended, on occasion of its latest guidelines update in 2007) - with increasingly greater importance being placed on factors associated with hygiene and oral health. The present study offers a critical review of the relationship between dental treatment, bacteremia and bacterial endocarditis.
    MeSH term(s) Antibiotic Prophylaxis ; Bacteremia/etiology ; Bacteremia/prevention & control ; Endocarditis, Bacterial/etiology ; Endocarditis, Bacterial/prevention & control ; Humans ; Mouth/microbiology ; Tooth Extraction/adverse effects
    Language English
    Publishing date 2008-06-01
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 2171573-7
    ISSN 1698-6946 ; 1698-4447
    ISSN (online) 1698-6946
    ISSN 1698-4447
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5809: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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