Article: Long-Term Carbapenems Antimicrobial Stewardship Program.
Antibiotics (Basel, Switzerland)
2020 Volume 10, Issue 1
Abstract: Objective: To evaluate clinical and antibiotic resistance impact of carbapenems stewardship programs.: Methods: descriptive study, pre-post-intervention, between January 2012 and December 2019; 350-bed teaching hospital. Prospective audit and ... ...
Abstract | Objective: To evaluate clinical and antibiotic resistance impact of carbapenems stewardship programs. Methods: descriptive study, pre-post-intervention, between January 2012 and December 2019; 350-bed teaching hospital. Prospective audit and feedback to prescribers was carried out between January 2015 and December 2019. We evaluate adequacy of carbapenems prescription to local guidelines and compare results between cases with accepted or rejected intervention. Analysis of antibiotic-consumption and hospital-acquired multidrug-resistant (MDR) bloodstream infections (BSIs) was performed. Results: 1432 patients were followed. Adequacy of carbapenems prescription improved from 49.7% in 2015 to 80.9% in 2019 ( Conclusions: the decrease and better use of carbapenems achieved could have clinical and ecological impact over five years, reduce inpatient days, hospital-acquired MDR BSIs, and candidemia, despite the increase in other antibiotic-consumption. |
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Language | English |
Publishing date | 2020-12-26 |
Publishing country | Switzerland |
Document type | Journal Article |
ZDB-ID | 2681345-2 |
ISSN | 2079-6382 |
ISSN | 2079-6382 |
DOI | 10.3390/antibiotics10010015 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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