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  1. Book ; Online: Chapter How to become a pastry chef: a statistical analysis through the company requirements

    MARIANI, PAOLO / Marletta, Andrea

    (Proceedings e report)

    2021  

    Series title Proceedings e report
    Keywords Labour Market ; Professional figures ; Food & Beverage sector ; Logistic Regression ; Factor analysis
    Language English
    Size 1 electronic resource (4 pages)
    Publisher Firenze University Press
    Publishing place Florence
    Document type Book ; Online
    Note English
    HBZ-ID HT030381464
    ISBN 9788855183048 ; 8855183044
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Chapter Quality of life in Health Care: focus on patients

    Digrandi, Angela / Pilo, Cinzia / Benedan, Laura / Mariani, Paolo / Zenga, Mariangela

    (Proceedings e report)

    2023  

    Series title Proceedings e report
    Keywords Society & social sciences ; Quality of Life ; Questionnaire ; Patients ; Health care
    Language English
    Size 1 electronic resource (5 pages)
    Publisher Firenze University Press, Genova University Press
    Publishing place Florence
    Document type Book ; Online
    Note English
    HBZ-ID HT030381712
    ISBN 9791221501063
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online: Chapter Patient-generated evidence in Epidermolysis Bullosa (EB): Development of a questionnaire to assess the Quality of Life

    Pilo, Cinzia / Benedan, Laura / El Hachem, May / Galeone, Carlotta / Mariani, Paolo / Tadini, Gianluca

    (Proceedings e report)

    2021  

    Series title Proceedings e report
    Keywords Social research & statistics ; Epidermolysis Bullosa ; Patient-centered approach ; Quality of Life ; Pseudo-Delphi
    Language 0|e
    Size 1 electronic resource (5 pages)
    Publisher Firenze University Press
    Publishing place Florence
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021616611
    ISBN 9788855184618 ; 885518461X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book ; Online: Chapter Development of an innovative methodology to define patient-designed quality of life: a new version of a wellknown concept in healthcare

    Bertoldi, Serena / Sofia, Francesca / Bartolini, Barbara / Benedan, Laura / Galeone, Carlotta / Mariani, Paolo / Zenga, Mariangela

    (Proceedings e report)

    2021  

    Series title Proceedings e report
    Keywords Social research & statistics ; Quality of Life ; QoL ; Pseudo Delphi ; Methodology ; Patient awareness ; Patient experience
    Language 0|e
    Size 1 electronic resource (5 pages)
    Publisher Firenze University Press
    Publishing place Florence
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021616617
    ISBN 9788855184618 ; 885518461X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article ; Online: Epidemiology, characteristics of disease and unmet needs of patients with generalized pustular psoriasis: a large Italian Delphi consensus.

    Prignano, Francesca / Atzori, Laura / Bellinato, Francesco / Damiani, Giovanni / Galeone, Carlotta / Mariani, Paolo / Potenza, Concetta / Scopinaro, Annalisa / Piaserico, Stefano / Fabbrocini, Gabriella

    Dermatology (Basel, Switzerland)

    2024  

    Abstract: Introduction: Generalized pustular psoriasis (GPP) is a rare and chronic, debilitating skin condition characterised, in its acute flare phase, by clinically severe and potentially life-threatening systemic manifestations. Data on GPP are still scanty, ... ...

    Abstract Introduction: Generalized pustular psoriasis (GPP) is a rare and chronic, debilitating skin condition characterised, in its acute flare phase, by clinically severe and potentially life-threatening systemic manifestations. Data on GPP are still scanty, particularly in Europe and at a national level. To provide expert indications on several disease-related and patient-related aspects of GPP, with specific focus to the Italian context.
    Methods: We conducted an iterative eDelphi study following the recommended criteria for reporting methods and results. After a thorough bibliographic review aimed to identify unknown or controversial issues in GPP, the following areas were investigated through a few specific questions/statements for each area: 1) disease epidemiology; 2) disease characteristics, with specific interest towards GPP flares; 3) diagnosis and diagnostic delay; 4) GPP treatment; 5) GPP patient journey and use of healthcare resources in Italy; 6) unmet needs and quality of life. An Executive Board of 9 principal investigators revised and approved the topics to be examined and overviewed the whole project. A total of 35 experts from different Italian areas, including 34 board-certified Italian dermatologists and one representative of patients' associations, took part in the study.
    Results: A high agreement in responses from Italian experts emerged during two eDelphi iterations on - among several other aspects - GPP prevalence and incidence in Italy, use of European Rare and Severe Psoriasis Expert Network diagnostic criteria, flare frequency and duration, best diagnostic and care pathway, and main unmet needs of Italian patients. On the other hand, a broad spectrum of treatments (of different drug classes) was reported both in the acute and chronic phases of GPP, and no consensus on the issue was thus achieved.
    Conclusions: Consensus findings from this Delphi study of GPP experts may be useful to fill gaps of knowledge and improve awareness of this rare disease, as well as to help clinical and public health management of GPP in Italy.
    Language English
    Publishing date 2024-03-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1099692-8
    ISSN 1421-9832 ; 1018-8665
    ISSN (online) 1421-9832
    ISSN 1018-8665
    DOI 10.1159/000538072
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui VI Zs.35: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Self-oriented anisotropic structure of G-hydrogels as a delicate balance between attractive and repulsive forces.

    Pepe, Alessia / Moretti, Paolo / Yoneda, Juliana S / Carducci, Federica / Itri, Rosangela / Mariani, Paolo

    Nanoscale

    2023  Volume 15, Issue 37, Page(s) 15196–15205

    Abstract: Guanine (G) hydrogels are very attractive materials made by the supramolecular organization of G-derivatives in water. In this paper, hydrogels composed of guanosine 5'-monophosphate (GMP) and guanosine (Gua), that make long, flexible and knotted G- ... ...

    Abstract Guanine (G) hydrogels are very attractive materials made by the supramolecular organization of G-derivatives in water. In this paper, hydrogels composed of guanosine 5'-monophosphate (GMP) and guanosine (Gua), that make long, flexible and knotted G-quadruplexes, were investigated by small- and wide-angle X-ray scattering (SAXS and WAXS) to comprehend the origin of their unique orientational properties. The SAXS intensity, analysed at a fixed scattering vector modulus
    Language English
    Publishing date 2023-09-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2515664-0
    ISSN 2040-3372 ; 2040-3364
    ISSN (online) 2040-3372
    ISSN 2040-3364
    DOI 10.1039/d3nr01348k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Small-angle scattering from flat bilayers containing correlated scattering length density inhomogeneities.

    Spinozzi, Francesco / Barbosa, Leandro R S / Corucci, Giacomo / Mariani, Paolo / Itri, Rosangela

    Journal of applied crystallography

    2023  Volume 56, Issue Pt 5, Page(s) 1348–1360

    Abstract: Model lipid bilayers have been widely employed as a minimal system to investigate the structural properties of biological membranes by small-angle X-ray (SAXS) and neutron scattering (SANS) techniques. These have nanometre resolution and can give ... ...

    Abstract Model lipid bilayers have been widely employed as a minimal system to investigate the structural properties of biological membranes by small-angle X-ray (SAXS) and neutron scattering (SANS) techniques. These have nanometre resolution and can give information regarding membrane thickness and scattering length densities (SLDs) of polar and apolar regions. However, biological membranes are complex systems containing different lipids and protein species, in which lipid domains can be dynamically assembled and disassembled. Therefore, SLD variations can occur within the biomembrane. In this work, a novel method has been developed to simulate SAXS and SANS profiles obtained from large unilamellar vesicles containing SLD inhomogeneities that are spatially correlated over the membrane surface. Such inhomogeneities are represented by cylindrical entities with equivalent SLDs. Stacking of bilayers is also included in the model, with no correlation between horizontal and vertical order. The model is applied to a lipid bilayer containing SLD inhomogeneities representing pores, lipid domains, and transmembrane, partially immersed and anchored proteins. It is demonstrated that all the structural information from the host lipid bilayer and from the SLD inhomogeneity can be consistently retrieved by a combined analysis of experimental SAXS and SANS data through the methodology proposed here.
    Language English
    Publishing date 2023-08-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2020879-0
    ISSN 1600-5767 ; 0021-8898
    ISSN (online) 1600-5767
    ISSN 0021-8898
    DOI 10.1107/S1600576723006143
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Unveiling the mono-rhamnolipid and di-rhamnolipid mechanisms of action upon plasma membrane models

    Motta, Alessandra Marega / Donato, Maressa / Mobbili, Giovanna / Mariani, Paolo / Itri, Rosangela / Spinozzi, Francesco

    Journal of colloid and interface science. 2022 May 25,

    2022  

    Abstract: Rhamnolipids (RLs) are biosurfactants with significant tensioactive and emulsifying properties. They are mainly composed by mono-RL and di-RL components. Although there are numerous studies concerning their molecular properties, information is scarce ... ...

    Abstract Rhamnolipids (RLs) are biosurfactants with significant tensioactive and emulsifying properties. They are mainly composed by mono-RL and di-RL components. Although there are numerous studies concerning their molecular properties, information is scarce regarding the mechanisms by which each of the two components interacts with cell membranes. Herein, we performed phase-contrast and fluorescence microscopy experiments on plasma membrane models represented by giant-unilamellar-vesicles (GUVs) composed of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), 2-[[(E,2S,3R)-1,3-dihydroxy-2-(octadecanoylamino)octadec-4-enyl]peroxy-hydroxyphosphoryl]oxyethyl-trimethylazanium (sphingomyelin, SM) and (3β)-cholest-5-en-3-ol (cholesterol, CHOL) (1:1:1 molar ratio), which present liquid-order (Lo) liquid-disorder (Ld) phase coexistence, in the presence of either mono-RL or di-RL in 0.06-0.25 mM concentration range. A new method has been developed to determine area and volume of GUVs with asymmetrical shape and a kinetic model describing GUV-RL interaction in terms of two mechanisms, RL-insertion and pore formation, has been worked out. Results show that the insertion of mono-RL in the membrane outer leaflet is the dominant process with no pore formation and a negligible effect in modifying membrane permeability, but induces lipid mixing. Conversely, the di-RL-GUV interaction begins with the insertion mechanism and, as the time passes by, the pore formation process occurs. The analyses of di-RL show that the whole process is only relevant in the Ld phase with a higher extent to 0.25 mM than to 0.06 mM.
    Keywords biosurfactants ; cholesterol ; fluorescence microscopy ; kinetics ; membrane permeability ; plasma membrane ; rhamnolipids ; sphingomyelins
    Language English
    Dates of publication 2022-0525
    Publishing place Elsevier Inc.
    Document type Article
    Note Pre-press version
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2022.05.145
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 71/707: Show issues

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  9. Article ; Online: Unveiling the mono-rhamnolipid and di-rhamnolipid mechanisms of action upon plasma membrane models.

    Marega Motta, Alessandra / Donato, Maressa / Mobbili, Giovanna / Mariani, Paolo / Itri, Rosangela / Spinozzi, Francesco

    Journal of colloid and interface science

    2022  Volume 624, Page(s) 579–592

    Abstract: Rhamnolipids (RLs) are biosurfactants with significant tensioactive and emulsifying properties. They are mainly composed by mono-RL and di-RL components. Although there are numerous studies concerning their molecular properties, information is scarce ... ...

    Abstract Rhamnolipids (RLs) are biosurfactants with significant tensioactive and emulsifying properties. They are mainly composed by mono-RL and di-RL components. Although there are numerous studies concerning their molecular properties, information is scarce regarding the mechanisms by which each of the two components interacts with cell membranes. Herein, we performed phase-contrast and fluorescence microscopy experiments on plasma membrane models represented by giant-unilamellar-vesicles (GUVs) composed of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), 2-[[(E,2S,3R)-1,3-dihydroxy-2-(octadecanoylamino) octadec-4-enyl]peroxy-hydroxyphosphoryl]oxyethyl-trimethylazanium (sphingomyelin, SM) and (3β)-cholest-5-en-3-ol (cholesterol, CHOL) (1:1:1 M ratio), which present liquid-order (L
    MeSH term(s) Cell Membrane ; Decanoates ; Glycolipids ; Lipid Bilayers ; Phosphatidylcholines ; Rhamnose/analogs & derivatives ; Sphingomyelins ; Unilamellar Liposomes
    Chemical Substances Decanoates ; Glycolipids ; Lipid Bilayers ; Phosphatidylcholines ; Sphingomyelins ; Unilamellar Liposomes ; rhamnolipid ; rhamnopyranosyl-3-hydroxydecanoyl-3-hydroxydecanoate (37134-61-5) ; Rhamnose (QN34XC755A)
    Language English
    Publishing date 2022-05-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2022.05.145
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 71/707: Show issues

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  10. Article ; Online: Semitransparent Perovskite Solar Cells with Ultrathin Protective Buffer Layers.

    Magliano, Erica / Mariani, Paolo / Agresti, Antonio / Pescetelli, Sara / Matteocci, Fabio / Taheri, Babak / Cricenti, Antonio / Luce, Marco / Di Carlo, Aldo

    ACS applied energy materials

    2023  Volume 6, Issue 20, Page(s) 10340–10353

    Abstract: Semitransparent perovskite solar cells (ST-PSCs) are increasingly important in a range of applications, including top cells in tandem devices and see-through photovoltaics. Transparent conductive oxides (TCOs) are commonly used as transparent electrodes, ...

    Abstract Semitransparent perovskite solar cells (ST-PSCs) are increasingly important in a range of applications, including top cells in tandem devices and see-through photovoltaics. Transparent conductive oxides (TCOs) are commonly used as transparent electrodes, with sputtering being the preferred deposition method. However, this process can damage exposed layers, affecting the electrical performance of the devices. In this study, an indium tin oxide (ITO) deposition process that effectively suppresses sputtering damage was developed using a transition metal oxides (TMOs)-based buffer layer. An ultrathin (<10 nm) layer of evaporated vanadium oxide or molybdenum oxide was found to be effective in protecting against sputtering damage in ST-PSCs for tandem applications, as well as in thin perovskite-based devices for building-integrated photovoltaics. The identification of minimal parasitic absorption, the high work function and the analysis of oxygen vacancies denoted that the TMO layers are suitable for use in ST-PSCs. The highest fill factor (FF) achieved was 76%, and the efficiency (16.4%) was reduced by less than 10% when compared with the efficiency of gold-based PSCs. Moreover, up-scaling to 1 cm
    Language English
    Publishing date 2023-10-05
    Publishing country United States
    Document type Journal Article
    ISSN 2574-0962
    ISSN (online) 2574-0962
    DOI 10.1021/acsaem.3c00735
    Database MEDical Literature Analysis and Retrieval System OnLINE

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