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  1. Article ; Online: Caffeine Mouth Rinse Plus Ingestion Improves the 10-Km Time Trial Compared to Caffeine Mouth Rinse Alone.

    Marinho, Alisson Henrique / da Silva, Jean Marcos / Brandão, Vitor Fon do Nascimento / Jatobá, Sarah Gomes / Júnior, Pedro Balikian / Ataide-Silva, Thays / Sousa, Filipe Antônio de Barros / Bastos-Silva, Victor José / de Araujo, Gustavo Gomes

    Research quarterly for exercise and sport

    2024  , Page(s) 1–8

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-01-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 225654-x
    ISSN 2168-3824 ; 0270-1367
    ISSN (online) 2168-3824
    ISSN 0270-1367
    DOI 10.1080/02701367.2023.2293121
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Caffeine, but Not Creatine, Improves Anaerobic Power Without Altering Anaerobic Capacity in Healthy Men During a Wingate Anaerobic Test.

    Marinho, Alisson Henrique / Silva-Cavalcante, Marcos David / Cristina-Souza, Gislaine / Sousa, Filipe Antonio de Barros / Ataide-Silva, Thays / Bertuzzi, Romulo / de Araujo, Gustavo Gomes / Lima-Silva, Adriano Eduardo

    International journal of sport nutrition and exercise metabolism

    2024  Volume 34, Issue 3, Page(s) 137–144

    Abstract: There is a lack of evidence on the additional benefits of combining caffeine (CAF) and creatine (CRE) supplementation on anaerobic power and capacity. Thus, the aim of the present study was to test the effects of combined and isolated supplementation of ... ...

    Abstract There is a lack of evidence on the additional benefits of combining caffeine (CAF) and creatine (CRE) supplementation on anaerobic power and capacity. Thus, the aim of the present study was to test the effects of combined and isolated supplementation of CAF and CRE on anaerobic power and capacity. Twenty-four healthy men performed a baseline Wingate anaerobic test and were then allocated into a CRE (n = 12) or placebo (PLA; n = 12) group. The CRE group ingested 20 g/day of CRE for 8 days, while the PLA group ingested 20 g/day of maltodextrin for the same period. On the sixth and eighth days of the loading period, both groups performed a Wingate anaerobic test 1 hr after either CAF (5 mg/kg of body mass; CRE + CAF and PLA + CAF conditions) or PLA (5 mg/kg of body mass of cellulose; CRE + PLA and PLA + PLA conditions) ingestion. After the loading period, changes in body mass were greater (p < .05) in the CRE (+0.87 ± 0.23 kg) than in the PLA group (+0.13 ± 0.27 kg). In both groups, peak power was higher (p = .01) in the CAF (1,033.4 ± 209.3 W) than in the PLA trial (1,003.3 ± 204.4 W), but mean power was not different between PLA and CAF trials (p > .05). In conclusion, CAF, but not CRE ingestion, increases anaerobic power. Conversely, neither CRE nor CAF has an effect on anaerobic capacity.
    MeSH term(s) Humans ; Male ; Anaerobiosis ; Caffeine/pharmacology ; Creatine ; Cross-Over Studies ; Double-Blind Method ; Polyesters
    Chemical Substances Caffeine (3G6A5W338E) ; Creatine (MU72812GK0) ; Polyesters
    Language English
    Publishing date 2024-03-07
    Publishing country United States
    Document type Clinical Study ; Journal Article
    ZDB-ID 1101115-4
    ISSN 1543-2742 ; 1050-1606 ; 1526-484X
    ISSN (online) 1543-2742
    ISSN 1050-1606 ; 1526-484X
    DOI 10.1123/ijsnem.2023-0191
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Effects of caffeine ingestion on cardiopulmonary responses during a maximal graded exercise test: a systematic review with meta-analysis and meta-regression

    Marinho, Alisson Henrique / Lopes-Silva, João Paulo / Cristina-Souza, Gislaine / Sousa, Filipe Antônio de Barros / Ataide-Silva, Thays / Lima-Silva, Adriano Eduardo / Araujo, Gustavo Gomes de / Silva‑Cavalcante, Marcos David

    Critical Reviews in Food Science and Nutrition. 2024 Jan. 2, v. 64, no. 1 p.127-139

    2024  

    Abstract: While the effects of caffeine ingestion on endurance performance are well known, its effects on cardiopulmonary responses during a maximal graded exercise test have been less explored. This study systematically reviewed and meta-analyzed studies ... ...

    Abstract While the effects of caffeine ingestion on endurance performance are well known, its effects on cardiopulmonary responses during a maximal graded exercise test have been less explored. This study systematically reviewed and meta-analyzed studies investigating the effects of caffeine ingestion on cardiopulmonary responses during a maximal graded exercise test. A search was performed in four databases, and study quality was assessed using the PEDro scale. Data reported by the selected studies were pooled using random-effects meta-analysis, with selected moderator effects assessed via meta-regression. Twenty-one studies with good and excellent methodological quality were included in this review. Compared to placebo, caffeine increased peak minute ventilation (SMD = 0.33; p = 0.01) and time to exhaustion (SMD = 0.41; p = 0.01). However, meta-regression showed no moderating effects of dosage and timing of caffeine ingestion, stage length, or total length of GXT (all p > 0.05). Caffeine ingestion did not affect peak oxygen uptake (SMD = 0.13; p = 0.42), peak heart rate (SMD = 0.27; p = 0.07), peak blood lactate concentration (SMD = 0.60; p = 0.09), peak tidal volume (SMD = 0.10; p = 0.69), peak breathing frequency (SMD =0.20; p = 0.23), or peak power output (SMD = 0.22; p = 0.28). The results of this systematic review with meta-analysis suggest that caffeine increases time to exhaustion and peak minute ventilation among the cardiopulmonary variables assessed during GXT.
    Keywords blood ; caffeine ; exercise test ; fatigue strength ; food science ; heart rate ; ingestion ; lactic acid ; meta-analysis ; nutrition ; peak oxygen uptake ; placebos ; systematic review ; tidal volume ; Sport nutrition ; exercise physiology ; exercise performance ; respiratory system ; cardiovascular responses
    Language English
    Dates of publication 2024-0102
    Size p. 127-139.
    Publishing place Taylor & Francis
    Document type Article ; Online
    ZDB-ID 1037504-1
    ISSN 1549-7852 ; 1040-8398
    ISSN (online) 1549-7852
    ISSN 1040-8398
    DOI 10.1080/10408398.2022.2104807
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Caffeine alters the breathing pattern during high-intensity whole-body exercise in healthy men.

    Marinho, Alisson Henrique / Cristina-Souza, Gislaine / Santos, Pâmela Souza / Santos-Mariano, Ana Carla / Rodacki, André / De-Oliveira, Fernando Roberto / Bertuzzi, Romulo / Lima-Silva, Adriano Eduardo

    European journal of applied physiology

    2022  Volume 122, Issue 6, Page(s) 1497–1507

    Abstract: Purpose: The current study investigated the effect of caffeine on the breathing pattern during a high-intensity whole-body exercise.: Methods: Using a randomized, crossover, counterbalanced, and double-blind design, twelve healthy men ingested either ...

    Abstract Purpose: The current study investigated the effect of caffeine on the breathing pattern during a high-intensity whole-body exercise.
    Methods: Using a randomized, crossover, counterbalanced, and double-blind design, twelve healthy men ingested either 5 mg.kg
    Results: Caffeine ingestion increased time to task failure in relation to the placebo (368.1 ± 49.6 s vs. 328.5 ± 56.6 s, p = 0.005). Caffeine also increased tidal volume and inspiratory time throughout the exercise (p < 0.05). Compared to task failure with placebo, task failure with caffeine intake was marked by higher (p < 0.05) minute ventilation (134.8 ± 16.4 vs. 147.6 ± 18.2 L.min
    Conclusion: In conclusion, ingestion of caffeine alters the breathing pattern by increasing tidal volume and lengthening the inspiratory phase of the respiratory cycle. These findings suggest that caffeine affects the ventilatory system, which may account, in part, for its ergogenic effects during high-intensity whole-body exercises.
    MeSH term(s) Caffeine/pharmacology ; Double-Blind Method ; Exercise/physiology ; Humans ; Male ; Oxygen Consumption ; Performance-Enhancing Substances ; Respiratory Rate
    Chemical Substances Performance-Enhancing Substances ; Caffeine (3G6A5W338E)
    Language English
    Publishing date 2022-04-09
    Publishing country Germany
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 124793-1
    ISSN 1439-6327 ; 1432-1025 ; 0301-5548 ; 1439-6319
    ISSN (online) 1439-6327 ; 1432-1025
    ISSN 0301-5548 ; 1439-6319
    DOI 10.1007/s00421-022-04934-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Effects of caffeine ingestion on cardiopulmonary responses during a maximal graded exercise test: a systematic review with meta-analysis and meta-regression.

    Marinho, Alisson Henrique / Lopes-Silva, João Paulo / Cristina-Souza, Gislaine / Sousa, Filipe Antônio de Barros / Ataide-Silva, Thays / Lima-Silva, Adriano Eduardo / Araujo, Gustavo Gomes de / Silva-Cavalcante, Marcos David

    Critical reviews in food science and nutrition

    2022  Volume 64, Issue 1, Page(s) 127–139

    Abstract: While the effects of caffeine ingestion on endurance performance are well known, its effects on cardiopulmonary responses during a maximal graded exercise test have been less explored. This study systematically reviewed and meta-analyzed studies ... ...

    Abstract While the effects of caffeine ingestion on endurance performance are well known, its effects on cardiopulmonary responses during a maximal graded exercise test have been less explored. This study systematically reviewed and meta-analyzed studies investigating the effects of caffeine ingestion on cardiopulmonary responses during a maximal graded exercise test. A search was performed in four databases, and study quality was assessed using the PEDro scale. Data reported by the selected studies were pooled using random-effects meta-analysis, with selected moderator effects assessed via meta-regression. Twenty-one studies with good and excellent methodological quality were included in this review. Compared to placebo, caffeine increased peak minute ventilation (SMD = 0.33; p = 0.01) and time to exhaustion (SMD = 0.41; p = 0.01). However, meta-regression showed no moderating effects of dosage and timing of caffeine ingestion, stage length, or total length of GXT (all p > 0.05). Caffeine ingestion did not affect peak oxygen uptake (SMD = 0.13; p = 0.42), peak heart rate (SMD = 0.27; p = 0.07), peak blood lactate concentration (SMD = 0.60; p = 0.09), peak tidal volume (SMD = 0.10; p = 0.69), peak breathing frequency (SMD =0.20; p = 0.23), or peak power output (SMD = 0.22; p = 0.28). The results of this systematic review with meta-analysis suggest that caffeine increases time to exhaustion and peak minute ventilation among the cardiopulmonary variables assessed during GXT.
    MeSH term(s) Caffeine ; Exercise Test ; Eating
    Chemical Substances Caffeine (3G6A5W338E)
    Language English
    Publishing date 2022-07-27
    Publishing country United States
    Document type Meta-Analysis ; Systematic Review
    ZDB-ID 1037504-1
    ISSN 1549-7852 ; 1040-8398
    ISSN (online) 1549-7852
    ISSN 1040-8398
    DOI 10.1080/10408398.2022.2104807
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The rating of perceived exertion is able to differentiate the post-matches metabolomic profile of elite U-20 soccer players.

    Marinho, Alisson Henrique / Sousa, Filipe Antonio de Barros / Vilela, Rubens de Alcântara Moura Pimentel / Balikian, Pedro / de Souza Bento, Edson / de Mendonça Aquino, Thiago / Crispim, Alessandre / Ataide-Silva, Thays / de Araujo, Gustavo Gomes

    European journal of applied physiology

    2021  Volume 122, Issue 2, Page(s) 371–382

    Abstract: Purpose: The study aimed to assess the metabolic impact of elite Brazilian U-20 players using the rating of perceived exertion scale (RPE) to discriminate metabolomics sensitivity post-two soccer games separated by a short recovery interval.: Methods!# ...

    Abstract Purpose: The study aimed to assess the metabolic impact of elite Brazilian U-20 players using the rating of perceived exertion scale (RPE) to discriminate metabolomics sensitivity post-two soccer games separated by a short recovery interval.
    Methods: Urine was collected immediately and then 20 h after two soccer matches of elite Brazilian U-20 players. RPE was collected after games. The spectra were pre-processed using TopSpin
    Results: The results showed that the metabolic pathways related to energy production, cellular damage, and organic stresses were changed immediately after the game. 20 h after the games, antioxidant and anti-inflammatory pathways related to cell recovery were identified (e.g., gallic acid, ascorbate, and betaine). The matrix of positive correlations between metabolites was more predominant and stronger after game 2 than game 1. T-distribution registered metabolites discriminated below and above 7 on the RPE scale. Athletes with higher RPE values showed a high metabolite profile related to muscle damage (e.g., creatine, creatinine, and glycine) and energy production (e.g., creatine, formate, pyruvate, 1,3 dihydroxyacetone) 20 h post-soccer match. There was a different metabolic profile between athletes with higher and lower RPE values.
    Conclusion: Metabolomics analysis made it possible to observe the metabolic impacts of energy production and muscular damage. RPE identified internal load changes within the group as a result of match intensity in soccer. The correlation matrix indicated a greater predominance of positive and strong correlations between metabolites in the second game compared to the first game.
    MeSH term(s) Athletic Performance/physiology ; Biomarkers/urine ; Brazil ; Humans ; Male ; Metabolomics ; Physical Exertion/physiology ; Soccer/physiology ; Young Adult
    Chemical Substances Biomarkers
    Language English
    Publishing date 2021-11-05
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 124793-1
    ISSN 1439-6327 ; 1432-1025 ; 0301-5548 ; 1439-6319
    ISSN (online) 1439-6327 ; 1432-1025
    ISSN 0301-5548 ; 1439-6319
    DOI 10.1007/s00421-021-04838-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Acute metformin administration increases mean power and the early Power phase during a Wingate test in healthy male subjects.

    Bastos-Silva, Victor José / Marinho, Alisson Henrique / Bezerra da Silva, José Bruno / de Barros Sousa, Filipe Antônio / Learsi, Sara / Balikian, Pedro / Gomes de Araujo, Gustavo

    European journal of sport science

    2021  Volume 22, Issue 7, Page(s) 1065–1072

    Abstract: The present study tested the hypothesis that acute metformin would increase peak power measured during a Wingate test. Fourteen men (24 ± 6 years; 75.8 ± 10.2 kg; 177 ± 7 cm) participated in four test sessions, conducted in a crossover, counterbalanced, ... ...

    Abstract The present study tested the hypothesis that acute metformin would increase peak power measured during a Wingate test. Fourteen men (24 ± 6 years; 75.8 ± 10.2 kg; 177 ± 7 cm) participated in four test sessions, conducted in a crossover, counterbalanced, double-blind model. The first and second sessions consisted of anthropometric measurements and one Wingate test per day to assess test-retest reliability. In the last two sessions, the Wingate tests were performed on metformin (500 mg capsule, 1 hour before) or placebo (cellulose capsule, 1 hour before) condition. No differences were found between the placebo and metformin for peak power (1056.8 ± 215.8 W vs. 1095.2 ± 199.3 W, respectively;
    MeSH term(s) Adult ; Cross-Over Studies ; Exercise Test ; Healthy Volunteers ; Humans ; Lactic Acid/blood ; Male ; Metformin/administration & dosage ; Muscle Strength ; Physical Exertion ; Reproducibility of Results ; Young Adult
    Chemical Substances Lactic Acid (33X04XA5AT) ; Metformin (9100L32L2N)
    Language English
    Publishing date 2021-06-13
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial
    ISSN 1536-7290
    ISSN (online) 1536-7290
    DOI 10.1080/17461391.2021.1930191
    Database MEDical Literature Analysis and Retrieval System OnLINE

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