Article ; Online: Clinical Coronary In-Stent Restenosis Follow-Up after Treatment and Analyses of Clinical Outcomes.
Arquivos brasileiros de cardiologia
2015 Volume 104, Issue 5, Page(s) 375–386
Abstract: Background: Clinical in-stent restenosis (CISR) is the main limitation of coronary angioplasty with stent implantation.: Objective: Describe the clinical and angiographic characteristics of CISR and the outcomes over a minimum follow-up of 12 months ... ...
| Abstract | Background: Clinical in-stent restenosis (CISR) is the main limitation of coronary angioplasty with stent implantation. Objective: Describe the clinical and angiographic characteristics of CISR and the outcomes over a minimum follow-up of 12 months after its diagnosis and treatment. Methods: We analyzed in 110 consecutive patients with CISR the clinical presentation, angiographic characteristics, treatment and combined primary outcomes (cardiovascular death, nonfatal acute myocardial infarction [AMI]) and combined secondary (unstable angina with hospitalization, target vessel revascularization and target lesion revascularization) during a minimal follow-up of one year. Results: Mean age was 61 ± 11 years (68.2% males). Clinical presentations included acute coronary syndrome (ACS) in 62.7% and proliferative ISR in 34.5%. CISR was treated with implantation of drug-eluting stents (DES) in 36.4%, Bare Metal Stent (BMS) in 23.6%, myocardial revascularization surgery in 18.2%, balloon angioplasty in 15.5% and clinical treatment in 6.4%. During a median follow-up of 19.7 months, the primary outcome occurred in 18 patients, including 6 (5.5%) deaths and 13 (11.8%) AMI events. Twenty-four patients presented a secondary outcome. Predictors of the primary outcome were CISR with DES (HR = 4.36 [1.44-12.85]; p = 0.009) and clinical treatment for CISR (HR = 10.66 [2.53-44.87]; p = 0.001). Treatment of CISR with BMS (HR = 4.08 [1.75-9.48]; p = 0.001) and clinical therapy (HR = 6.29 [1.35-29.38]; p = 0.019) emerged as predictors of a secondary outcome. Conclusion: Patients with CISR present in most cases with ACS and with a high frequency of adverse events during a medium-term follow-up. |
|---|---|
| MeSH term(s) | Acute Coronary Syndrome/etiology ; Acute Coronary Syndrome/mortality ; Acute Coronary Syndrome/therapy ; Adult ; Aged ; Aged, 80 and over ; Angina Pectoris/etiology ; Angina Pectoris/mortality ; Angina Pectoris/therapy ; Coronary Angiography ; Coronary Restenosis/diagnostic imaging ; Coronary Restenosis/etiology ; Coronary Restenosis/mortality ; Coronary Restenosis/therapy ; Epidemiologic Methods ; Female ; Hospitalization ; Humans ; Male ; Middle Aged ; Myocardial Revascularization/methods ; Percutaneous Coronary Intervention/methods ; Stents ; Time Factors ; Treatment Outcome |
| Language | Portuguese |
| Publishing date | 2015-02-03 |
| Publishing country | Brazil |
| Document type | Journal Article ; Observational Study |
| ZDB-ID | 730261-7 |
| ISSN | 1678-4170 ; 0066-782X |
| ISSN (online) | 1678-4170 |
| ISSN | 0066-782X |
| DOI | 10.5935/abc.20140216 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
| Zs.A 548: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.