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  1. Article: Wunderlich Syndrome: Spontaneous Cystic Rupture on Account of Acquired Kidney Atrophy.

    Mariolis-Sapsakos, Theodoros / Nannou, Eirini / Angelis, Stavros / Filippou, Dimitrios

    Cureus

    2022  Volume 14, Issue 10, Page(s) e30386

    Abstract: Wunderlich syndrome is an uncommon condition of spontaneous subcapsular and perirenal hemorrhage of atraumatic etiology in the kidney, with the potential to spread to the retroperitoneal region beyond the perirenal fascias. Its clinical manifestations ... ...

    Abstract Wunderlich syndrome is an uncommon condition of spontaneous subcapsular and perirenal hemorrhage of atraumatic etiology in the kidney, with the potential to spread to the retroperitoneal region beyond the perirenal fascias. Its clinical manifestations usually include Lenk's triad, namely, acute flank pain, flank mass, and hemodynamic instability, which vary depending on the causative underlying renal pathology. Tumor bleeding of benign and malignant renal neoplasms is the most common cause of this syndrome, followed by vascular disorders and renal cystic diseases. Here, we report the case of a unilateral subcapsular renal hematoma on account of a left atrophic kidney with parapelvic cystic formations and variant hypoplastic vasculature which was successfully managed via radical nephrectomy after initial conservative treatment. Spontaneous cystic rupture contributed to the emergence of the syndrome, and its mechanisms are being addressed.
    Language English
    Publishing date 2022-10-17
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.30386
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A Rare Case of Thyroid Metastasis From Colorectal Cancer: Diagnostic and Therapeutic Challenges.

    Lampropoulou, Dimitra Ioanna / Pliakou, Evangelia / Panagiotou, Maria Ourania / Mariolis-Sapsakos, Theodoros / Aravantinos, Gerasimos

    Cureus

    2023  Volume 15, Issue 12, Page(s) e50097

    Abstract: The incidence of thyroid metastases among patients suffering from primary colorectal cancer is rare, and only a few cases have been described in the literature. As these metastases are usually asymptomatic, they most frequently present as incidentalomas ... ...

    Abstract The incidence of thyroid metastases among patients suffering from primary colorectal cancer is rare, and only a few cases have been described in the literature. As these metastases are usually asymptomatic, they most frequently present as incidentalomas on follow-up imaging. Hereby, we present and discuss an interesting case of metastatic sigmoid adenocarcinoma of the thyroid gland, diagnosed and treated at our institution.
    Language English
    Publishing date 2023-12-07
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.50097
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Anatomy and Pathogenesis of Vascular Thoracic Outlet Syndrome.

    Perdikakis, Miltiadis / Sinou, Nikoleta / Angelis, Stavros / Tsakotos, George / Mariolis-Sapsakos, Theodoros / Piagkou, Maria / Filippou, Dimitrios

    Cureus

    2023  Volume 15, Issue 1, Page(s) e34470

    Abstract: The current literature review article describes the anatomy and pathogenesis of the vascular nature of thoracic outlet syndrome (TOS), as well as gathers the latest and most important information concerning its diagnostic methods and treatment. This ... ...

    Abstract The current literature review article describes the anatomy and pathogenesis of the vascular nature of thoracic outlet syndrome (TOS), as well as gathers the latest and most important information concerning its diagnostic methods and treatment. This syndrome's subcategory includes the venous and the arterial. Data for this review was accumulated through the PubMed database in which only scientific studies published in the last decade (2012-2022) were searched. PubMed offered 347 results, of which 23 were judged suitable and used. Non-invasive methods both for the diagnosis and the treatment of vascular TOS are gaining ground. Medicine, at this point, finds itself on the verge of slowly putting aside the previous invasive gold-standard methods, to be used only in the most urgent situations. The vascular thoracic outlet condition is a rare form of TOS but is also the most trouble-causing one and the deadliest. Fortunately, it can be more efficiently managed because of the current medical innovations. However, further research is needed to establish their already confirmed effectiveness, so they can be even more widely trusted and used.
    Language English
    Publishing date 2023-01-31
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.34470
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: A standardized nutraceutical supplement contributes to pain relief, improves quality of life and regulates inflammation in knee osteoarthritis patients; A randomized clinical trial.

    Valsamidou, Evdokia / Amerikanou, Charalampia / Tzavara, Chara / Skarpas, George / Mariolis-Sapsakos, Theodoros D / Zoumpoulakis, Panagiotis / Kaliora, Andriana C

    Heliyon

    2023  Volume 9, Issue 9, Page(s) e20143

    Abstract: Osteoarthritis (OA) is a degenerative disease of the joints that affects greatly the elderly population and the health care systems and is on the increase due to aging and obesity. Interventions aim at palliative care and pharmaceutical therapies entail ... ...

    Abstract Osteoarthritis (OA) is a degenerative disease of the joints that affects greatly the elderly population and the health care systems and is on the increase due to aging and obesity. Interventions aim at palliative care and pharmaceutical therapies entail serious adverse events. Whereas polyphenols constitute a promising holistic approach in the arsenal of physicians, trials investigating biomarkers and questionnaires are scarce. As such, a randomized controlled trial (RCT) was conducted to evaluate the potency of a standardized polyphenolic supplement in the management of systemic inflammation, oxidative stress, pain and general quality of life (QoL) in patients with osteoarthritis. Sixty subjects were randomized to receive either a polyphenol supplement (curcuma phospholipid, rosemary extract, resveratrol, ascorbic acid), or an active comparator (ascorbic acid) twice, daily for 12 weeks. The group that received the polyphenols exhibited significantly lower symptoms of pain and improved physical function and QoL as it was depicted by validated questionnaires, compared to the control group. Furthermore, post intervention, inflammation was restrained in the polyphenol group. Since systemic inflammation promotes local inflammation, the decrease of pain herein might be attributed to the attenuation of systemic inflammation by the polyphenols.
    Language English
    Publishing date 2023-09-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e20143
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Liposarcoma of the pelvic fossa masquerading as hematoma: a rare case report and its surgical management.

    Zarokosta, Maria / Foutsitzi, Aikaterini / Roditis, Spyridon / Karanasiou, Vasilissa / Nannou, Eirini / Mariolis-Sapsakos, Theodoros

    Journal of surgical case reports

    2021  Volume 2021, Issue 6, Page(s) rjab120

    Abstract: Liposarcomas constitute rare malignant tumors of the soft tissue, with wide anatomical distribution. The prompt diagnosis of a liposarcoma is extremely challenging since these tumors tend to remain asymptomatic, until they grow enough to displace ... ...

    Abstract Liposarcomas constitute rare malignant tumors of the soft tissue, with wide anatomical distribution. The prompt diagnosis of a liposarcoma is extremely challenging since these tumors tend to remain asymptomatic, until they grow enough to displace adjacent anatomical structures. In the presented case, a 55-year-old Caucasian male proceeded to our institution complaining about irreducible swelling of the right iliac fossa and constant discomfort, over the course of a year. His medical history revealed injury of the right groin and pelvis a year ago. The diagnosis was ilioinguinal liposarcoma masquerading as hematoma, due to the previous injury. The patient underwent primary complete tumor resection, and the operation was uneventful. The essential diagnostic and surgical steps for the management of a liposarcoma, mimicking a hematoma are meticulously described.
    Language English
    Publishing date 2021-06-12
    Publishing country England
    Document type Case Reports
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjab120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Anomalous anatomic trajectory of the superior thyroid artery encountered during thyroidectomy. A rare case report.

    Zarokosta, Maria / Foutsitzi, Aikaterini / Mpartziotas, Iraklis / Manthas, Alexandros / Tsiaoussis, John / Mariolis-Sapsakos, Theodoros

    Journal of surgical case reports

    2021  Volume 2021, Issue 4, Page(s) rjab030

    Abstract: Superior thyroid artery (STA), which is one of the primary arteries supplying to the thyroid gland, constitutes a severe consideration of both surgeons and interventional radiologists. Knowledge of the origin, the trajectory, the branching patterns and ... ...

    Abstract Superior thyroid artery (STA), which is one of the primary arteries supplying to the thyroid gland, constitutes a severe consideration of both surgeons and interventional radiologists. Knowledge of the origin, the trajectory, the branching patterns and the anatomic aberrations of STA are of paramount clinical significance, due to its proximity to the external branch of the superior laryngeal nerve and the potentiality of accidental hemorrhage. The present manuscript reports for the first time the anomalous trajectory of the left STA, coursing superficially, through the left sternothyroid muscle and underlines the clinical significance of such aberrations.
    Language English
    Publishing date 2021-04-24
    Publishing country England
    Document type Case Reports
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjab030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Meletius the Monk (c. 8th to 9th century AD) and the blood circulation.

    Tsoucalas, Gregory / Mariolis-Sapsakos, Theodoros / Sgantzos, Markos

    European heart journal

    2018  Volume 38, Issue 9, Page(s) 624–626

    MeSH term(s) Anatomy, Regional/history ; Blood Circulation ; History, 16th Century ; History, 17th Century ; History, Medieval ; Humans ; Medical Illustration/history
    Language English
    Publishing date 2018-07-27
    Publishing country England
    Document type Biography ; Historical Article ; Journal Article
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehx077
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: COVID-19 Vaccine Uptake among Healthcare Workers: A Systematic Review and Meta-Analysis.

    Galanis, Petros / Vraka, Irene / Katsiroumpa, Aglaia / Siskou, Olga / Konstantakopoulou, Olympia / Katsoulas, Theodoros / Mariolis-Sapsakos, Theodoros / Kaitelidou, Daphne

    Vaccines

    2022  Volume 10, Issue 10

    Abstract: The vaccine-induced immunity of healthcare workers (HCWs) is crucial to controlling the COVID-19 pandemic. Therefore, we conducted a systematic review and meta-analysis to assess the COVID-19 vaccine uptake among HCWs worldwide and to identify predictors ...

    Abstract The vaccine-induced immunity of healthcare workers (HCWs) is crucial to controlling the COVID-19 pandemic. Therefore, we conducted a systematic review and meta-analysis to assess the COVID-19 vaccine uptake among HCWs worldwide and to identify predictors of vaccination. We searched Scopus, Web of Science, Medline, PubMed, ProQuest, CINAHL, and medRxiv up to 25 August 2022. We applied the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. We found 25 studies including 491,624 vaccinated HCWs, while the full sample included 555,561 HCWs. The overall proportion of vaccinated HCWs was 77.3%. Vaccine uptake for studies that were conducted in North America (85.6%) was higher than the proportion for studies that were conducted in Asia (79.5%), Europe (72.8%), and Africa (65.6%). The overall prevalence of COVID-19 vaccine uptake was 83.6% and 77.4% for physicians and nurses, respectively. Older age, white race, physicians' profession, seasonal influenza vaccine, direct COVID-19 patient care, and confidence in COVID-19 vaccine safety and effectiveness were positive predictors of vaccine uptake, while history of SARS-CoV-2 infection was a negative predictor. Deep understanding of the factors that influence HCWs' decisions to receive a COVID-19 vaccine is critical to implementing tailored communication strategies for HCWs who are at risk for not getting vaccinated.
    Language English
    Publishing date 2022-09-29
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines10101637
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Surgical administration of multiple glomus tumors in uncommon anatomic regions in a 17-year-old female. A rare case report.

    Mariolis-Sapsakos, Theodoros / Zarokosta, Maria / Lazaridis, Nikolaos / Mourtzoukou, Despoina / Vlachodimitropoulos, Dimitrios / Patrinos, Antonios / Foutsitzi, Aikaterini / Paraskevas, George

    Journal of surgical case reports

    2022  Volume 2022, Issue 1, Page(s) rjab609

    Abstract: Glomus tumor (GT) constitutes a rare, benign, soft-tissue tumor emerging from neuro-myo-arterial glomus bodies. Due to its rarity, and absence of typical symptoms, GT is usually misdiagnosed, with a potential risk of rupture and infection, or even ... ...

    Abstract Glomus tumor (GT) constitutes a rare, benign, soft-tissue tumor emerging from neuro-myo-arterial glomus bodies. Due to its rarity, and absence of typical symptoms, GT is usually misdiagnosed, with a potential risk of rupture and infection, or even malignant transformation. The present manuscript reports a rare case of a 17-year-old young woman with multiple GTs in her lower back, breach and left thigh that was surgically treated. The manuscript aims to highlight the importance of prompt diagnosis and surgical treatment of this peculiar tumor in young patients and raise surgeons' awareness.
    Language English
    Publishing date 2022-01-21
    Publishing country England
    Document type Case Reports
    ZDB-ID 2580919-2
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjab609
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Predictors of Willingness of the General Public to Receive a Second COVID-19 Booster Dose or a New COVID-19 Vaccine: A Cross-Sectional Study in Greece.

    Galanis, Petros / Vraka, Irene / Katsiroumpa, Aglaia / Siskou, Olga / Konstantakopoulou, Olympia / Katsoulas, Theodoros / Mariolis-Sapsakos, Theodoros / Kaitelidou, Daphne

    Vaccines

    2022  Volume 10, Issue 7

    Abstract: Given the concerns of waning immunity from the primary COVID-19 vaccines and the first booster dose, we conducted an online cross-sectional study in May 2022 to investigate willingness to receive a second COVID-19 booster dose or a new COVID-19 vaccine ... ...

    Abstract Given the concerns of waning immunity from the primary COVID-19 vaccines and the first booster dose, we conducted an online cross-sectional study in May 2022 to investigate willingness to receive a second COVID-19 booster dose or a new COVID-19 vaccine and its associated factors. Overall, 62% of the participants were willing to be vaccinated, 25.8% were unsure, and 12.3% were unwilling to be vaccinated. The main reasons against accepting a second COVID-19 booster dose/new COVID-19 vaccine were concerns about the side effects and the effectiveness and the opinion that further vaccination is unnecessary. Males, younger individuals, participants without a previous COVID-19 diagnosis, and those with good/very good self-perceived physical health were significantly more frequently willing to receive a second COVID-19 booster dose or a new COVID-19 vaccine. Additionally, increased fear of the COVID-19, increased trust in COVID-19 vaccinations, and decreased fear of a second booster dose or a new COVID-19 vaccine was associated with increased willingness. Our results show some hesitancy and unwillingness toward further COVID-19 vaccination and indicate that the fear of COVID-19 and trust in COVID-19 vaccination affects public opinion.
    Language English
    Publishing date 2022-06-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines10071061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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