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Article ; Online: Direct co-registration of [

Debacker, Jens M / Maris, Luna / Cordier, Fleur / Creytens, David / Deron, Philippe / Descamps, Benedicte / D'Asseler, Yves / De Man, Kathia / Keereman, Vincent / Libbrecht, Sasha / Schelfhout, Vanessa / Van de Vijver, Koen / Vanhove, Christian / Huvenne, Wouter

European journal of nuclear medicine and molecular imaging

2023  Volume 50, Issue 7, Page(s) 2127–2139

Abstract: Purpose: Recent technical advancements in PET imaging have improved sensitivity and spatial resolution. Consequently, clinical nuclear medicine will be confronted with PET images on a previously unfamiliar resolution. To better understand [: Methods: ...

Abstract Purpose: Recent technical advancements in PET imaging have improved sensitivity and spatial resolution. Consequently, clinical nuclear medicine will be confronted with PET images on a previously unfamiliar resolution. To better understand [
Methods: A total of five patients diagnosed with a malignancy of the head and neck were injected with a clinical activity of [
Results: The co-registration between the autoradiographs and their corresponding histopathology was successful in all specimens. The use of this novel methodology allowed direct comparison of autoradiography and histopathology and enabled the visualisation of uncharted heterogeneity in [
Conclusion: We here describe a novel methodology enabling the direct co-registration of [
Trial registration: ClinicalTrials.gov Identifier: NCT05068687.
MeSH term(s) Humans ; Fluorodeoxyglucose F18 ; Positron Emission Tomography Computed Tomography ; Radiopharmaceuticals ; Feasibility Studies ; Neoplasms ; Positron-Emission Tomography/methods
Chemical Substances Fluorodeoxyglucose F18 (0Z5B2CJX4D) ; Radiopharmaceuticals
Language English
Publishing date 2023-03-01
Publishing country Germany
Document type Journal Article
ZDB-ID 8236-3
ISSN 1619-7089 ; 0340-6997 ; 1619-7070
ISSN (online) 1619-7089
ISSN 0340-6997 ; 1619-7070
DOI 10.1007/s00259-023-06153-z
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