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  1. AU="Marques-Rocha, José Luiz"
  2. AU="Kausar, Jamilla"
  3. AU="Abdelsalam, Adel M"
  4. AU="Zhu, Leran"
  5. AU="Li, Xiao-Qiong"
  6. AU="Althouse, W E"
  7. AU="Hu, Brian"
  8. AU="Li, Qijun"
  9. AU="Schofield, Paul"
  10. AU="Maenhout, Thomas"
  11. AU="Hall, John C"
  12. AU="Ho, Chun-Ming"
  13. AU="Dymond, Ian W"
  14. AU="Álvarez, María Noel"
  15. AU="J. Muñoz i Vidal"
  16. AU="Zeng, Guangming"
  17. AU="Luigi Mazzeo, Pier"
  18. AU="Danilova, Olga V"
  19. AU="Jian, Shang"
  20. AU="Jae-Gyu Jeon"
  21. AU="Andrade, Letícia G."
  22. AU="Hosseinzadeh, Sara Ali"
  23. AU="Lee, Kristen"
  24. AU="Gentile, Giulia"
  25. AU="Shoben, Abigail B."
  26. AU="Rowe, Elizabeth"
  27. AU="Pandemic Response COVID-19 Research Collaboration Platform for HCQ/CQ Pooled Analyses"
  28. AU="Rahali, Anwar"
  29. AU="Zhang, Zhuang-Wei"
  30. AU="Townsend, Elizabeth C"
  31. AU="Lange, Mona V"
  32. AU="Bruner, Brenda G"
  33. AU="Michael Craigen"
  34. AU="Lambard, G."
  35. AU="Dempsey, Connor P"
  36. AU=Li Youxian
  37. AU="Bhosale, Chanakya R"

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  1. Artikel ; Online: Quality of life of transgender people under the lens of social determinants of health: a scoping review protocol.

    Coswosck, Kaio Henrique Cesconetto / Marques-Rocha, Jose Luiz / Moreira, Juliana Almeida / Guandalini, Valdete Regina / Lopes-Júnior, Luís Carlos

    BMJ open

    2023  Band 13, Heft 7, Seite(n) e067575

    Abstract: Introduction: There is an urgent need for knowledge about the transgender population to inform the development of clinical protocols and training of health professionals on the unique issues affecting this population. Discussing transgender quality of ... ...

    Abstract Introduction: There is an urgent need for knowledge about the transgender population to inform the development of clinical protocols and training of health professionals on the unique issues affecting this population. Discussing transgender quality of life (QoL) through the lens of social determinants of health (SDOHs) would enable gender-specific health interventions. Here, we aimed to review the evidence on the QoL of transgender people from an SDOH perspective.
    Methods and analysis: A scoping review (ScR) protocol following the Preferred Reporting Items for Systematic Review and Meta-Analyses extension for Scoping Reviews statement and guided by the Joanna Briggs Institute was used. MEDLINE/PubMed, Cochrane Library, Embase, PsycINFO, Web of Science, Scopus and registry sites such as ClinicalTrials.gov and WHO ICTRP will be searched. Additional sources to be searched include ProQuest Dissertations/Theses Global, British Library, Google Scholar and Preprints for Health Sciences-medRXiv. Two independent researchers will carry out the selection, data charting and data synthesis. No date restriction will be applied in this ScR. The search will be restricted to articles published in English, Spanish and Portuguese. The results will be presented in tables, narrative summaries and graphs and will be graded on the type of data presented and the results. The search strategy will be updated in April 2023. The expected completion date of this ScR is July 2023.
    Ethics and dissemination: This ScR protocol does not require ethical approval. Dissemination plans include peer-reviewed publications, conference presentations to be shared with experts in the field, and advisory groups to inform discussions on future research. It is hoped that our findings will be of interest to practitioners, researchers, stakeholders, public and private managers, and the general population concerned with this emerging public health issue.
    Trial registration number: osf.io/9ukz6.
    Mesh-Begriff(e) Humans ; Quality of Life ; Transgender Persons ; Social Determinants of Health ; Academies and Institutes ; Ethnicity ; Research Design ; Review Literature as Topic
    Sprache Englisch
    Erscheinungsdatum 2023-07-31
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2022-067575
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  2. Artikel ; Online: Waist Circumference as a Tool for Identifying Visceral Fat in Women with Non-Metastatic Breast Cancer.

    Felício de Souza Mamede, Vanusa / de Almeida Marques Bernabé, Rayne / Leopoldino da Silva, Larissa / Gonçalves Santos, Thalita / Gomes Fontana, Luana / Machado, Janine Martins / Albergaria, Ben-Hur / Marques-Rocha, Jose Luiz / Guandalini, Valdete Regina

    Nutrition and cancer

    2024  Band 76, Heft 4, Seite(n) 316–324

    Abstract: Abdominal adiposity is associated with tumor development and poor clinical outcomes in breast cancer (BC) and can be identified by the measurement of waist circumference (WC) and visceral adipose tissue (VAT). This study aimed to evaluate the association ...

    Abstract Abdominal adiposity is associated with tumor development and poor clinical outcomes in breast cancer (BC) and can be identified by the measurement of waist circumference (WC) and visceral adipose tissue (VAT). This study aimed to evaluate the association between waist circumference (WC) and imaging measurement of central adiposity according to age group in women with BC. Abdominal adiposity was assessed by WC and VAT, obtained by dual-energy X-ray absorptiometry (DXA). Body mass index (BMI) was assessed. The presence of inflammation was investigated by measuring C-Reactive Protein (CRP) levels. Multivariate linear regression models were applied to verify the association between WC and VAT. The significance level adopted for all tests was 5%. This study included 112 women with a mean age of 55.5 ± 11.4 years. After adjusted models, WC remained associated with VAT and for every centimeter increase in WC, there was an increase of 3.12 cm
    Mesh-Begriff(e) Humans ; Female ; Adult ; Middle Aged ; Aged ; Waist Circumference ; Intra-Abdominal Fat/diagnostic imaging ; Intra-Abdominal Fat/metabolism ; Intra-Abdominal Fat/pathology ; Breast Neoplasms/pathology ; Obesity/metabolism ; Body Mass Index ; Obesity, Abdominal
    Sprache Englisch
    Erscheinungsdatum 2024-02-05
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 424433-3
    ISSN 1532-7914 ; 0163-5581
    ISSN (online) 1532-7914
    ISSN 0163-5581
    DOI 10.1080/01635581.2024.2304691
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  3. Artikel ; Online: Skeletal muscle mass obtained by anthropometric equation and presence of sarcopenia in postmenopausal women.

    Felipe, Thaís Loureiro / Grili, Patrícia Paula da Fonseca / Vidigal, Camila Vilarinho / Albergaria, Ben-Hur / da Cruz, Geise Ferreira / Marques-Rocha, José Luiz / Guandalini, Valdete Regina

    Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia

    2024  Band 46

    Abstract: Objective: To analyze the amount of muscle and the presence of sarcopenia in postmenopausal women using different methods, verifying the agreement between them as to skeletal muscle mass (SMM).: Methods: This cross-sectional observational study was ... ...

    Abstract Objective: To analyze the amount of muscle and the presence of sarcopenia in postmenopausal women using different methods, verifying the agreement between them as to skeletal muscle mass (SMM).
    Methods: This cross-sectional observational study was conducted with postmenopausal women aged ≥ 50 years. SMM was obtained from a predictive equation, Bioelectrical Impedance (BIA), and Dual Energy X-Ray Absorptiometry (DXA). The skeletal muscle mass index (SMI) and the appendicular skeletal muscle mass index (ASMI) were calculated. The cut-off point of SMI was determined for the population itself. The agreement between the SMI obtained using the different methods was verified. Sarcopenia was diagnosed according to the criteria proposed by the European Working Group on Sarcopenia in Older People 2 (EWGSOP2). The significance level adopted for all tests was 5.0%.
    Results: A total of 112 women were evaluated, with an average age of 66.1 ± 5.65 years. Among them, 51.8% were sufficiently active and 43.8% were overweight and obese. The SMI cut-offs were 6.46 kg/m
    Conclusion: The predictive equation showed the expected agreement in estimating skeletal muscle mass in postmenopausal women, offering a viable and accurate alternative.
    Mesh-Begriff(e) Humans ; Female ; Sarcopenia/epidemiology ; Sarcopenia/diagnostic imaging ; Sarcopenia/diagnosis ; Cross-Sectional Studies ; Postmenopause/physiology ; Aged ; Muscle, Skeletal/diagnostic imaging ; Muscle, Skeletal/anatomy & histology ; Middle Aged ; Absorptiometry, Photon ; Electric Impedance ; Anthropometry
    Sprache Englisch
    Erscheinungsdatum 2024-03-15
    Erscheinungsland Brazil
    Dokumenttyp Journal Article ; Observational Study
    ZDB-ID 2105176-8
    ISSN 1806-9339 ; 0100-7203
    ISSN (online) 1806-9339
    ISSN 0100-7203
    DOI 10.61622/rbgo/2024AO09
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  4. Artikel ; Online: Nutrient Patterns and Risk of Osteopenia in Postmenopausal Women.

    Grili, Patricia Paula da Fonseca / Vidigal, Camila Vilarinho / Cruz, Geise Ferreira da / Albergaria, Ben-Hur / Marques-Rocha, José Luiz / Pereira, Taísa Sabrina Silva / Guandalini, Valdete Regina

    Nutrients

    2023  Band 15, Heft 7

    Abstract: Nutrient patterns (NPs) and the synergistic effect between nutrients have been shown to be associated with changes in bone mineral density (BMD). This study aimed to identify NPs and to associate them with BMD categories in postmenopausal women. This ... ...

    Abstract Nutrient patterns (NPs) and the synergistic effect between nutrients have been shown to be associated with changes in bone mineral density (BMD). This study aimed to identify NPs and to associate them with BMD categories in postmenopausal women. This cross-sectional, observational, analytical study was carried out with women in menopause for at least 12 months, aged ≥50 years. Sociodemographic, lifestyle, and clinical variables were investigated. BMD was assessed using dual energy X-ray absorptiometry. A dietary assessment was conducted using a food frequency questionnaire, and three nutrient patterns (NP1, NP2, and NP3) were extracted from the principal component analysis. Multivariate logistic regression was applied to investigate the association between BMD classifications and NP consumption. A total of 124 women, aged on average, 66.8 ± 6.1 years, were evaluated. Of these, 41.9% had osteopenia and 36.3% had osteoporosis. The NP1 (OR: 6.64, [CI95%: 1.56-28.16];
    Mesh-Begriff(e) Female ; Humans ; Postmenopause ; Cross-Sectional Studies ; Bone Diseases, Metabolic/epidemiology ; Bone Diseases, Metabolic/etiology ; Bone Density ; Vitamins ; Vitamin A ; Osteoporosis, Postmenopausal/epidemiology ; Osteoporosis, Postmenopausal/etiology
    Chemische Substanzen Vitamins ; Vitamin A (11103-57-4)
    Sprache Englisch
    Erscheinungsdatum 2023-03-29
    Erscheinungsland Switzerland
    Dokumenttyp Observational Study ; Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15071670
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  5. Artikel ; Online: Conicity index as an indicator of abdominal obesity in individuals with chronic kidney disease on hemodialysis.

    Martins, Cleodice Alves / do Prado, Camila Bruneli / Santos Ferreira, Júlia Rabelo / Cattafesta, Monica / Dos Santos Neto, Edson Theodoro / Haraguchi, Fabiano Kenji / Marques-Rocha, José Luiz / Salaroli, Luciane Bresciani

    PloS one

    2023  Band 18, Heft 4, Seite(n) e0284059

    Abstract: Background: The conicity index is indicated as a tool for assessing the nutritional status of renal individuals undergoing hemodialysis. Thus, this study aimed to estimate the prevalence of abdominal obesity using the conicity index in individuals with ... ...

    Abstract Background: The conicity index is indicated as a tool for assessing the nutritional status of renal individuals undergoing hemodialysis. Thus, this study aimed to estimate the prevalence of abdominal obesity using the conicity index in individuals with chronic kidney disease undergoing hemodialysis to verify its association with sociodemographic, clinical, and lifestyle factors.
    Materials and methods: This is a cross-sectional study with 941 individuals undergoing hemodialysis in a metropolitan area in southeastern Brazil. The conicity index was estimated and cutoffs of 1.275 and 1.285 for men and women, respectively, were used. For the analysis of the results, binary logistic regression was performed and the odds ratio (OR) was estimated with their respective confidence intervals (95% CI).
    Results: The conicity index was high in 56.54% of men (95% CI: 34.34-70.16) and 43.46% of women (95% CI: 38.45-55.20). We found that both adult men (OR = 3.71; 95% CI: 2.27-6.07) and adult women (OR = 4.06; 95% CI: 2.41-6.84) were more likely to have abdominal obesity, as well as self-declared mixed-raced (OR: 1.74; 95% CI: 1.01-3.00) and single men (OR: 1.64; 95% CI: 1.00-2.68).
    Conclusions: The conicity index is an important anthropometric indicator to estimate abdominal obesity in individuals with chronic kidney disease on hemodialysis.
    Mesh-Begriff(e) Male ; Adult ; Humans ; Female ; Obesity, Abdominal/complications ; Obesity, Abdominal/epidemiology ; Cross-Sectional Studies ; Waist Circumference ; Obesity/complications ; Obesity/epidemiology ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/epidemiology ; Renal Insufficiency, Chronic/therapy ; Renal Dialysis ; Body Mass Index
    Sprache Englisch
    Erscheinungsdatum 2023-04-19
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0284059
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  6. Artikel ; Online: Agreement between maximum and mean handgrip strength measurements in cancer patients.

    de Almeida Marques, Rayne / de Souza, Vanusa Felício / do Rosario, Thainá Cezini / da Silva Garcia, Maria Rita Pereira / Pereira, Taísa Sabrina Silva / Marques-Rocha, José Luiz / Guandalini, Valdete Regina

    PloS one

    2022  Band 17, Heft 7, Seite(n) e0270631

    Abstract: Background and aim: Handgrip strength (HGS) can be used to identify probable sarcopenia, by measuring maximum strength and/or through the average of three measurements. This study analyzed the agreement between maximum and mean HGS measurements in ... ...

    Abstract Background and aim: Handgrip strength (HGS) can be used to identify probable sarcopenia, by measuring maximum strength and/or through the average of three measurements. This study analyzed the agreement between maximum and mean HGS measurements in identifying probable sarcopenia in cancer patients.
    Methods: Adult individuals of both sexes diagnosed with malignant neoplasm were evaluated. HGS (kg/f) was measured in both hands and nutritional status defined by the Patient-Generated Subjective Global Assessment (PG-SGA). Bland-Altman, Intraclass Correlation Coefficient (ICC), and Cronbach's Alpha tests were applied to assess the agreement between measurements.
    Results: One hundred forty-one patients aged 60.0 ± 14.2 years were evaluated. There was a predominance of elderly (57.4%), male (53.2%), and non-white (58.2%) individuals, with tumors located in the lower gastrointestinal tract (GIT) (36.9%) and with suspected or some degree of malnutrition (61.0%). For men, the Bland-Altman test showed a mean error of 1.37 (95% CI-1.03 to 3.80) for dominant HGS (DHGS) and 1.50 (95% CI-1.60 to 4.60) for non-dominant HGS (NDHGS), while for women the values were 1.34 (95% CI-0.27 to 2.95) and 1.14 (95% CI-1.10 to 3.39), respectively. The ICC showed excellent reproducibility (> 0.90) and the Cronbach's Alpha was satisfactory (0.99).
    Conclusion: Despite the satisfactory agreement observed between maximum and mean HGS values, in this study, individuals of both sexes with probable sarcopenia were better identified through mean values.
    Mesh-Begriff(e) Adult ; Aged ; Cross-Sectional Studies ; Female ; Hand Strength ; Humans ; Male ; Neoplasms/complications ; Reproducibility of Results ; Sarcopenia/diagnosis
    Sprache Englisch
    Erscheinungsdatum 2022-07-01
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0270631
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  7. Artikel ; Online: Low appendicular skeletal muscle mass index is associated with the anthropometric variables of post-menopausal women.

    da Cruz, Geise Ferreira / Lunz, Tatiana Mion / Rocha de Jesus, Tatielle / Costa, Mariana Braga / Vidigal, Camila Vilarinho / Albergaria, Ben-Hur / Marques-Rocha, José Luiz / Guandalini, Valdete Regina

    BMC geriatrics

    2022  Band 22, Heft 1, Seite(n) 639

    Abstract: Background: Skeletal muscle mass is a central component of body composition and its decline is enhanced during aging. We verified the association between the appendicular skeletal muscle mass index (ASMI) with the anthropometric variables, biochemical ... ...

    Abstract Background: Skeletal muscle mass is a central component of body composition and its decline is enhanced during aging. We verified the association between the appendicular skeletal muscle mass index (ASMI) with the anthropometric variables, biochemical variables, and lifestyle of postmenopausal women.
    Methods: Cross-sectional observational study conducted with postmenopausal women. Sociodemographic, clinical, lifestyle, physical activity level, biochemical, and anthropometric markers were collected. Body composition was assessed by dual-energy densitometry. Multivariate logistic regression analysis was applied.
    Results: One hundred fourteen women aged in average 66.0 ± 5.8 years were evaluated. There was a significant association between ASMI and age (p = 0.004), body mass (p < 0.001), body mass index (BMI) (p < 0.001), adductor pollicis muscle thickness (APMT) (p < 0.001), plasma calcium levels (p = 0.003), calf circumference (CC), and waist circumference (WC) (p < 0.001 for both). Adjusted regression analyses revealed the influence of BMI, CC, and APMT in the 1st tertile of ASMI (p < 0.05), BMI and CC in the 2rd tertile of ASMI.
    Conclusions: ASMI was associated with BMI and muscle mass reserve indicators such as CC and DAPMT. In clinical practice, this indicates that simple, low-cost measures with good applicability can be used to predict and track the risk of depletion of skeletal muscle mass and consequent sarcopenia.
    Mesh-Begriff(e) Anthropometry ; Body Composition ; Body Mass Index ; Cross-Sectional Studies ; Female ; Humans ; Muscle, Skeletal ; Postmenopause ; Sarcopenia
    Sprache Englisch
    Erscheinungsdatum 2022-08-03
    Erscheinungsland England
    Dokumenttyp Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 2059865-8
    ISSN 1471-2318 ; 1471-2318
    ISSN (online) 1471-2318
    ISSN 1471-2318
    DOI 10.1186/s12877-022-03313-y
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  8. Artikel: Dietary consumption of selenium inversely associated with osteoporosis in postmenopausal women.

    Grili, Patricia Paula da Fonseca / Vidigal, Camila Vilarinho / da Cruz, Geise Ferreira / Albergaria, Ben Hur / Marques-Rocha, José Luiz / Pereira, Taísa Sabrina Silva / Guandalini, Valdete Regina

    Frontiers in nutrition

    2022  Band 9, Seite(n) 997414

    Abstract: Background: Osteoporosis is a skeletal disease characterized by reduced bone mineral density (BMD), which increases the risk of falls and fractures and reduces mobility. Some nutrients have a well-established role in maintaining bone health and ... ...

    Abstract Background: Osteoporosis is a skeletal disease characterized by reduced bone mineral density (BMD), which increases the risk of falls and fractures and reduces mobility. Some nutrients have a well-established role in maintaining bone health and preventing osteoporosis, while selenium (Se) has aroused interest in bone health possibly because of its anti-inflammatory and antioxidant capacity. The aim of this study was to evaluate the association between dietary Se consumption and BMD in postmenopausal women.
    Materials and methods: Cross-sectional, observational, analytical study carried out with women in menopause for at least 12 months, aged ≥ 50 years. Sociodemographic, lifestyle, and clinical data variables were studied. BMD was assessed using Dual Energy X-ray Absorptiometry (DXA) and the participants classified as having normal BMD, osteopenia, or osteoporosis. Dietary consumption of Se was assessed by the food frequency questionnaire (FFQ) and classified into quartiles of consumption. Multivariate logistic regression with three fit models was applied to investigate the association of BMD with Se consumption quartiles. The significance level adopted for all tests was 5.0%.
    Results: The final sample consisted of 124 women aged in average 66.8 ± 6.1 years and with a time since menopause of 19.6 ± 8.8 years. According to the BMD, 41.9% of the women had osteopenia and 36.3% osteoporosis. The mean consumption of Se was 154.4 ± 88.7 μg/day. The highest consumption of Se was observed among women with normal BMD (51.9%), whereas lower consumption levels were found in 57.7% of women with osteopenia and in 60.0% of women with osteoporosis (
    Conclusion: Se consumption was associated with BMD and postmenopausal women with higher Se consumption were less likely to have osteoporosis.
    Sprache Englisch
    Erscheinungsdatum 2022-09-12
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2022.997414
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  9. Artikel ; Online: Muscle strength is associated with fracture risk obtained by fracture risk assessment tool (FRAX) in women with breast cancer.

    de Almeida Marques Bernabé, Rayne / de Souza Vieira, Mariana / Felício de Souza, Vanusa / Gomes Fontana, Luana / Albergaria, Ben-Hur / Marques-Rocha, José Luiz / Guandalini, Valdete Regina

    BMC cancer

    2022  Band 22, Heft 1, Seite(n) 1115

    Abstract: Background: Women with breast cancer are at risk for the development of sarcopenia and occurrence of fractures. The initial and periodic screening of these conditions can prevent the risks of disability, poor quality of life, and death. The present ... ...

    Abstract Background: Women with breast cancer are at risk for the development of sarcopenia and occurrence of fractures. The initial and periodic screening of these conditions can prevent the risks of disability, poor quality of life, and death. The present study investigated the association between sarcopenia phenotypes and fracture risk, assessed by the Fracture Risk Assessment Tool (FRAX) in women with breast cancer.
    Methods: Cross-sectional study. It included women aged between 40 and 80 years, diagnosed with Luminal subtype breast cancer, with time of diagnosis ≤ 12 months, who had not started endocrine therapy, did not have metastasis, had not been treated for another malignancy, and had no recurrences. Sociodemographic, habits and lifestyle, clinical, anthropometric, and body composition variables were considered. Muscle strength, skeletal muscle mass, and physical performance were investigated using handgrip strength (HGS), appendicular skeletal muscle mass index (ASMI), and Timed Up and Go test (TUGT), respectively. Fracture risk was assessed using FRAX. Multiple linear regression models were conducted to verify the association between exposure variables and sarcopenia phenotypes. A significance level of p < 0.05 was adopted for all tests using the SPPS 25.0 program.
    Results: Sixty-two women with a mean age of 58.1 ± 10.4 years were evaluated. Of these, 66.1% self-declared to be non-white, 41.9% and 71.0% did not consume alcohol or smoke, respectively, and 61.3% were insufficiently active. A total of 45.2% had clinical stage II carcinoma and 65.5% had the invasive breast carcinoma histological subtype. There was a predominance of adequacy of HGS (88.7%), ASMI (94.5%), and TUGT (96.8%), as well as low risk of hip fractures (85.5%) and major fractures (82.3%). HGS remained associated with FRAX hip fractures (p = 0.007) and FRAX major fractures (p = 0.007) in the adjusted models, while ASMI was associated with body mass (p < 0.001).
    Conclusions: Low muscle strength was the sarcopenia phenotype that remained associated with fracture risk in women with breast cancer, independently of sociodemographic factors, level of physical activity, and clinical factors. In addition to the assessment of probable sarcopenia, this measurement may point out the risk of fractures.
    Mesh-Begriff(e) Female ; Humans ; Sarcopenia/pathology ; Hand Strength/physiology ; Cross-Sectional Studies ; Quality of Life ; Postural Balance ; Time and Motion Studies ; Muscle Strength/physiology ; Hip Fractures/complications ; Hip Fractures/epidemiology ; Risk Assessment ; Risk Factors ; Bone Density/physiology ; Neoplasms/complications
    Sprache Englisch
    Erscheinungsdatum 2022-11-01
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2041352-X
    ISSN 1471-2407 ; 1471-2407
    ISSN (online) 1471-2407
    ISSN 1471-2407
    DOI 10.1186/s12885-022-10203-4
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  10. Artikel ; Online: Influence of the appendicular skeletal muscle mass index on the bone mineral density of postmenopausal women.

    da Cruz, Geise Ferreira / Lunz, Tatiana Mion / de Jesus, Tatielle Rocha / Costa, Mariana Braga / Vidigal, Camila Vilarinho / Albergaria, Ben-Hur / Marques-Rocha, Jose Luiz / Guandalini, Valdete Regina

    BMC musculoskeletal disorders

    2021  Band 22, Heft 1, Seite(n) 861

    Abstract: Background: The appendicular skeletal muscle mass index (ASMI) is an important risk indicator for osteoporosis because of the anatomical proximity and metabolic connection between muscle and bone mass. The present study investigated the relationship ... ...

    Abstract Background: The appendicular skeletal muscle mass index (ASMI) is an important risk indicator for osteoporosis because of the anatomical proximity and metabolic connection between muscle and bone mass. The present study investigated the relationship between ASMI and the bone mineral density (BMD) categories of postmenopausal women.
    Methods: In this cross-sectional study with a probabilistic sample, sociodemographic, lifestyle, menopause time, anthropometric, and physical activity variables were collected. ASMI and BMD were assessed by dual-energy X-ray absorptiometry (DXA). Participants were grouped according to BMD values into normal density, osteopenia, and osteoporosis. Multivariate logistic regression models were applied to verify the influence of ASMI on BMD. Data were analyzed using the SPSS statistical software, version 22. The significance level for all tests was set at 5%.
    Results: Of the 114 women analyzed, most were between 60 and 69.9 years of age (62.3%), on menopause for ≤19.0 (51.8%), self-declared brown race/color (49.1%), had < 4 years of education (41.2%), never smoked (69.0%) or drank alcohol (62.8%). Of these, 52.6% were classified as sufficiently active and 52.2% had regular sun exposure. Women with osteoporosis were older (p = 0.035), on menopause for a longer time (p = 0.011), underweight (p = 0.004), had adequate waist circumference (p = 0.017), and low ASMI values (p = 0.002). There was an association between the 1st tertile of ASMI and osteoporosis. However, after adjustments for age, race/color, and body mass index, the strength of association between BMD and ASMI was not maintained.
    Conclusions: ASMI was not associated with the BMD of the postmenopausal women evaluated. Total body and muscle mass, in addition to bone mass, should be monitored during menopause treatment. Longitudinal studies must be conducted to elucidate the mechanisms and gaps in this relationship.
    Mesh-Begriff(e) Absorptiometry, Photon ; Bone Density ; Child, Preschool ; Cross-Sectional Studies ; Female ; Humans ; Muscle, Skeletal/diagnostic imaging ; Postmenopause
    Sprache Englisch
    Erscheinungsdatum 2021-10-09
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2041355-5
    ISSN 1471-2474 ; 1471-2474
    ISSN (online) 1471-2474
    ISSN 1471-2474
    DOI 10.1186/s12891-021-04748-x
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