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  1. Article: Editorial: The ABCDEF bundle: Laying the foundations for long term wellness in ICU survivors.

    Vargas, Maria / Buonanno, Pasquale / Kotfis, Katarzyna / Marra, Annachiara

    Frontiers in medicine

    2022  Volume 9, Page(s) 1056056

    Language English
    Publishing date 2022-10-21
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2022.1056056
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Tracheostomy in COVID-19 patients: A matter of staff safety and mortality.

    Vargas, Maria / Marra, Annachiara / Servillo, Giuseppe

    American journal of otolaryngology

    2021  Volume 42, Issue 5, Page(s) 103007

    MeSH term(s) COVID-19 ; Humans ; Infectious Disease Transmission, Patient-to-Professional ; Respiration, Artificial ; SARS-CoV-2 ; Tracheostomy/adverse effects
    Language English
    Publishing date 2021-03-24
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 604541-8
    ISSN 1532-818X ; 0196-0709
    ISSN (online) 1532-818X
    ISSN 0196-0709
    DOI 10.1016/j.amjoto.2021.103007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: The authors reply.

    Marra, Annachiara / Brummel, Nathan E

    Critical care medicine

    2019  Volume 47, Issue 3, Page(s) e277

    MeSH term(s) Critical Care ; Critical Illness ; Humans ; Survivors ; Syndrome
    Language English
    Publishing date 2019-02-14
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000003610
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    Zs.A 1261: Show issues Location:
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  4. Article ; Online: The spectrum of psychological disorders in family members of patients suffering from delirium associated with critical illness: a prospective, observational study.

    Kotfis, Katarzyna / Maj, Patrycja / Szylińska, Aleksandra / Pankowiak, Maria / Reszka, Elżbieta / Ely, E Wesley / Marra, Annachiara

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 4562

    Abstract: During intensive care unit admission, relatives of critically ill patients can experience emotional distress. The authors hypothesized that families of patients who are diagnosed with intensive care unit (ICU) delirium experience more profound depression ...

    Abstract During intensive care unit admission, relatives of critically ill patients can experience emotional distress. The authors hypothesized that families of patients who are diagnosed with intensive care unit (ICU) delirium experience more profound depression and anxiety disorders related to stress than do families of patients without delirium. We performed a prospective observational single-center study including families of adult patients (age above 18 years) hospitalized in a 17-bed ICU of a university hospital for at least 48 h who completed research questionnaires at day 2 after admission and day 30 after initial evaluation using dedicated questionnaires (HADS, CECS, IES, PTSD-C). A total of 98 family members of patients hospitalized in the ICU were included in the final analysis (50 family members whose relatives were CAM-ICU positive (DEL+), and 48 family members of patients without delirium (DEL-)). No statistically significant differences in demographics and psychosocial data were found between the groups. In the follow-up 30 days after the first conversation with a family member, the mean PTSD score for the relatives of patients with delirium was 11.02 (Me = 13.0; SD = 5.74), and the mean score for nondelirious patients' family members was 6.42 (Me = 5.5; SD = 5.50; p < 0.001). A statistically significant increase in IES scores for family members of patients with delirium was observed for total PTSD (p = 0.001), IES-intrusion (p < 0.001), and IES-hyperarousal (p = 0.002). The prevalence of anxiety symptoms, depression, and posttraumatic stress disorder (PTSD) was higher in families of patients diagnosed with ICU delirium within 48 h of admission to the ICU. No factors increasing the depth of these disorders in family members of patients with ICU delirium were identified. Taking appropriate actions and thus providing families with appropriate support will contribute to the understanding of unfavorable emotional states, including anxiety, stress, depression, anger, agitation, or avoidance.
    MeSH term(s) Adult ; Humans ; Adolescent ; Critical Illness/psychology ; Prospective Studies ; Anxiety/epidemiology ; Anxiety/psychology ; Stress Disorders, Post-Traumatic/psychology ; Intensive Care Units ; Family/psychology ; Delirium/epidemiology ; Depression/epidemiology ; Depression/psychology
    Language English
    Publishing date 2024-02-24
    Publishing country England
    Document type Observational Study ; Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-53968-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: The Effects of the Pericapsular Nerve Group Block on Postoperative Pain in Patients with Hip Fracture: A Multicenter Study.

    Iacovazzo, Carmine / Sara, Rosario / Buonanno, Pasquale / Vargas, Maria / Coviello, Antonio / Punzo, Roberta / Maffei, Vincenzo / Marra, Annachiara

    Diagnostics (Basel, Switzerland)

    2024  Volume 14, Issue 8

    Abstract: Background: An adequate early mobilization followed by an effective and pain-free rehabilitation are critical for clinical and functional recovery after hip and proximal femur fracture. A multimodal approach is always recommended so as to reduce the ... ...

    Abstract Background: An adequate early mobilization followed by an effective and pain-free rehabilitation are critical for clinical and functional recovery after hip and proximal femur fracture. A multimodal approach is always recommended so as to reduce the administered dose of analgesics, drug interactions, and possible side effects. Peripheral nerve blocks should always be considered in addition to spinal or general anesthesia to prolong postoperative analgesia. The pericapsular nerve group (PENG) block appears to be a less invasive and more effective analgesia technique compared to other methods.
    Methods: We conducted multicenter retrospective clinical research, including 98 patients with proximal femur fracture undergoing osteosynthesis surgery within 48 h of occurrence of the fracture. Thirty minutes before performing spinal anesthesia, 49 patients underwent a femoral nerve (FN) block plus a lateral femoral cutaneous nerve (LCFN) block, and the other 49 patients received a PENG block. A non-parametric Wilcoxon-Mann-Whitney (α = 0.05) test was performed to evaluate the difference in resting and dynamic numerical rating scale (NRS) at 30 min, 6 h, 12 h, and 24 h.
    Results: the PENG block administration was more effective in reducing pain intensity compared to the FN block in association with the LFCN block, as seen in the resting and dynamic NRS at thirty minutes and 12 h follow-up.
    Conclusion: the PENG block was more effective in reducing pain intensity than the femoral nerve block associated with the lateral femoral cutaneous nerve block in patients with proximal femur fracture undergoing to osteosynthesis.
    Language English
    Publishing date 2024-04-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics14080827
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  6. Article ; Online: Is the Pao2:Fio2 Ratio the Best Marker to Monitor the Blood-Air Barrier Function in Acute Respiratory Distress Syndrome?

    Buonanno, Pasquale / Marra, Annachiara / Vargas, Maria / Iacovazzo, Carmine / Servillo, Giuseppe

    Critical care medicine

    2021  Volume 49, Issue 7, Page(s) e726–e727

    MeSH term(s) Blood Gas Analysis ; Blood-Air Barrier ; Humans ; Oxygen ; Respiratory Distress Syndrome ; Respiratory Function Tests
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2021-05-05
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000004973
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1261: Show issues Location:
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  7. Article ; Online: Preoperative anxiety: what are we really doing?

    Buonanno, Pasquale / Vargas, Maria / Marra, Annachiara / Iacovazzo, Carmine / Servillo, Giuseppe

    Acta bio-medica : Atenei Parmensis

    2021  Volume 92, Issue 3, Page(s) e2021277

    Abstract: ...

    Abstract .
    MeSH term(s) Anxiety/prevention & control ; Humans ; Preoperative Care
    Language English
    Publishing date 2021-07-01
    Publishing country Italy
    Document type Journal Article ; Comment
    ZDB-ID 2114240-3
    ISSN 2531-6745 ; 0392-4203
    ISSN (online) 2531-6745
    ISSN 0392-4203
    DOI 10.23750/abm.v92i3.9329
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    Zs.B 925: Show issues Location:
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  8. Article: Anesthetic management in a patient with Arnold-Chiari malformation type 1,5: A case report.

    Coviello, Antonio / Golino, Ludovica / Posillipo, Concetta / Marra, Annachiara / Tognù, Andrea / Servillo, Giuseppe

    Clinical case reports

    2022  Volume 10, Issue 2, Page(s) e05194

    Abstract: A 42-year-old male patient with Arnold-Chiari malformation type 1,5 (ACM-1,5) came to implant a hip prosthesis. He underwent a previous general anesthesia, with difficult airway management and complication in awakening. In this second surgery, an ... ...

    Abstract A 42-year-old male patient with Arnold-Chiari malformation type 1,5 (ACM-1,5) came to implant a hip prosthesis. He underwent a previous general anesthesia, with difficult airway management and complication in awakening. In this second surgery, an extradural approach was preferred to keep intracranial pressure and hemodynamics stable.
    Language English
    Publishing date 2022-02-04
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.5194
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  9. Article ; Online: Telemedicine in Cancer Pain Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

    Buonanno, Pasquale / Marra, Annachiara / Iacovazzo, Carmine / Franco, Massimo / De Simone, Stefania

    Pain medicine (Malden, Mass.)

    2022  Volume 24, Issue 3, Page(s) 226–233

    Abstract: Objective: Telemedicine is defined as the delivery of medical services through a variety of telecommunication tools. This novel approach can fit the needs of cancer patients who cannot often reach clinics due to their disabling symptoms. In this ... ...

    Abstract Objective: Telemedicine is defined as the delivery of medical services through a variety of telecommunication tools. This novel approach can fit the needs of cancer patients who cannot often reach clinics due to their disabling symptoms. In this population of patients, pain is undoubtedly the most important symptom which dramatically affects the quality of life. Our work aimed to investigate the effectiveness of telemedicine in the management of cancer pain in order to assess the feasibility of a combination between telemedicine and traditional in-person visits; we also propose a model of integration of these two approaches.
    Methods: We followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) framework to conduct our study. Quality assessment and risk of bias were performed according Cochrane criteria. Results were reported as mean differences and summarized using forest plots. We performed a trial sequential analysis (TSA) to assess the conclusiveness of our results.
    Results: Pain severity score and pain interference were lower for patients treated with telemedicine compared to those undergoing classical management (mean difference: -0.408; P =< .001 and -0.492; P = .004, respectively). TSA confirmed that our results were statistically significant and pointed out the need of other studies to reach the required sample size. PROSPERO registration: CRD42022333260.
    Conclusions: Telemedicine can be effectively used to manage cancer pain. This novel approach will certainly have a revolutionary economic and organizational impact on health care systems in the next future. Furthermore, the model herein proposed could help set up an algorithm to safely and efficiently implement telemedicine.
    MeSH term(s) Humans ; Cancer Pain ; Quality of Life ; Randomized Controlled Trials as Topic ; Telemedicine/methods ; Delivery of Health Care ; Neoplasms
    Language English
    Publishing date 2022-08-29
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 2015903-1
    ISSN 1526-4637 ; 1526-2375
    ISSN (online) 1526-4637
    ISSN 1526-2375
    DOI 10.1093/pm/pnac128
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  10. Article: The evolving approach to sedation in ventilated patients: a real world perspective.

    Marra, Annachiara / Pandharipande, Pratik P

    Annals of translational medicine

    2017  Volume 4, Issue 24, Page(s) 494

    Language English
    Publishing date 2017-01-18
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2893931-1
    ISSN 2305-5847 ; 2305-5839
    ISSN (online) 2305-5847
    ISSN 2305-5839
    DOI 10.21037/atm.2016.12.56
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