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  1. Article ; Online: Double trouble within the coronary sinus: What is the mechanism?

    Laborie, Guillaume / Jebberi, Zeynab / Marra, Céline / Bortone, Agustín

    Journal of cardiovascular electrophysiology

    2019  Volume 30, Issue 5, Page(s) 785–788

    MeSH term(s) Action Potentials ; Aged ; Catheter Ablation ; Coronary Sinus/physiopathology ; Electrophysiologic Techniques, Cardiac ; Heart Rate ; Humans ; Male ; Predictive Value of Tests ; Tachycardia, Supraventricular/diagnosis ; Tachycardia, Supraventricular/etiology ; Tachycardia, Supraventricular/physiopathology ; Tachycardia, Supraventricular/surgery ; Time Factors ; Treatment Outcome
    Language English
    Publishing date 2019-02-13
    Publishing country United States
    Document type Case Reports ; Video-Audio Media
    ZDB-ID 1025989-2
    ISSN 1540-8167 ; 1045-3873
    ISSN (online) 1540-8167
    ISSN 1045-3873
    DOI 10.1111/jce.13870
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2863: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: High-Power (40-50 W) Radiofrequency Ablation Guided by Unipolar Signal Modification for Pulmonary Vein Isolation: Experimental Findings and Clinical Results.

    Pambrun, Thomas / Durand, Cyril / Constantin, Marion / Masse, Alexandre / Marra, Céline / Meillet, Valentin / Haïssaguerre, Michel / Jaïs, Pierre / Bortone, Agustín

    Circulation. Arrhythmia and electrophysiology

    2019  Volume 12, Issue 6, Page(s) e007304

    Abstract: Background Although proposed to facilitate pulmonary vein isolation (PVI), high-power ablation may favor extracardiac damage. Negative component abolition of the unipolar signal reflects lesion transmurality. The present study sought to evaluate the ... ...

    Abstract Background Although proposed to facilitate pulmonary vein isolation (PVI), high-power ablation may favor extracardiac damage. Negative component abolition of the unipolar signal reflects lesion transmurality. The present study sought to evaluate the safety and efficacy of high-power ablation using unipolar signal modification as a local end point. Methods High power and standard power were compared in 4 swine and 100 consecutive patients referred for PVI. The first 50 patients were included in the control group (25-30 W) and the last 50 patients in the study group (40-50 W). Atrial radiofrequency applications were stopped 2 s (study group and swine) or 5 s (control group) after unipolar signal modification. Ventricular radiofrequency applications of 500 J (25 W·20 s versus 50 W·10 s) were performed at the swine epicardium. Results Swine gross necropsy did not show any extracardiac damage related to atrial lesions. At equal energy of 500 J, 50 W lesions were deeper (3±0.9 versus 2.6±1.1 mm; P=0.03) and wider (6.2±2 versus 5±2.3 mm; P=0.006) than 25 W lesions. No complications occurred during the clinical study, whatever the power output used for PVI. For a similar sinus rhythm maintenance at 12 months (90% versus 88%; P=0.75), the study group displayed higher first-pass PVI (92% versus 73%; P<0.001), lower acute pulmonary vein reconnection (2% versus 17%; P<0.001), reduced procedure time (73.1±18.2 versus 107.4±21.2 min; P<0.001), and ablation time (13±2.9 versus 30.3±8.8 min; P<0.001). Conclusions High-power PVI guided by unipolar signal modification safely decreases procedural burden while ensuring robust 12-month outcomes.
    MeSH term(s) Action Potentials ; Aged ; Animals ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/physiopathology ; Atrial Fibrillation/surgery ; Case-Control Studies ; Catheter Ablation/adverse effects ; Catheter Ablation/methods ; Female ; Heart Rate ; Humans ; Male ; Middle Aged ; Models, Animal ; Operative Time ; Prospective Studies ; Pulmonary Veins/physiopathology ; Pulmonary Veins/surgery ; Risk Factors ; Sus scrofa ; Time Factors ; Treatment Outcome
    Language English
    Publishing date 2019-06-05
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2426129-4
    ISSN 1941-3084 ; 1941-3149
    ISSN (online) 1941-3084
    ISSN 1941-3149
    DOI 10.1161/CIRCEP.119.007304
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6667: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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