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  1. Article ; Online: Hallazgos en los potenciales evocados auditivos del tallo cerebral en pacientes menores de 2 años con antecedente de hemorragia intraventricular.

    Gutiérrez-Palomares, M L / Luna-Martínez, J / Fraire-Martínez, M I / Núñez-Enriquez, J C

    Revista de neurologia

    2023  Volume 76, Issue 10, Page(s) 315–320

    Abstract: Introduction: There are few studies that describe the results of auditory pathway assessment in patients with a history of intraventricular haemorrhage (IVH) during the early years of life. Hypoacusis can occur from the earliest stages of IVH. Brainstem ...

    Title translation Findings in brainstem auditory evoked potentials in patients under 2 years of age with a history of intraventricular haemorrhage.
    Abstract Introduction: There are few studies that describe the results of auditory pathway assessment in patients with a history of intraventricular haemorrhage (IVH) during the early years of life. Hypoacusis can occur from the earliest stages of IVH. Brainstem auditory evoked potentials (BAEPs) are a useful tool for diagnosing auditory pathway disorders in early childhood. The aim of the present study was to describe the BAEPs findings in patients under 2 years of age with a history of IVH.
    Patients and methods: We conducted a retrospective observational study in patients under 2 years of age with a history of IVH referred to our hospital for BAEPs over a period of three years. Patients with genetic syndromes associated with hypoacusis were excluded. BAEPs were used to evaluate the presence or absence of any bioelectrical response and latencies of waves I, III and V, as well as of the intervals I-III, III-V and I-V, and also their morphology, amplitude, synchrony and reproducibility. A descriptive analysis was carried out with the calculation of frequencies and percentages.
    Results: A total of 122 patients were included. Fifty-one per cent of them had a history of Grade I IVH; 42%, Grade II; and 7%, Grades III or IV. A bioelectrical response was obtained in 243 auditory pathways (99.6%). The morphology was found to be altered in 6.2% of the auditory pathways, while amplitudes were decreased in 2.5% of those tested. Latencies for waves I and III were found to be prolonged in 2% and for wave V in 3.6% of patients. The hearing threshold was normal in 64.8%, and 35.2% of cases presented hypoacusis.
    Conclusions: The prevalence of hypoacusis was high in the sample analysed. Systematic follow-up using BAEPs is recommended in order to detect and treat problems in the auditory pathway in patients with IVH in a timely manner.
    MeSH term(s) Child, Preschool ; Humans ; Evoked Potentials, Auditory, Brain Stem/physiology ; Reproducibility of Results ; Hearing Loss ; Cerebral Hemorrhage ; Retrospective Studies ; Evoked Potentials, Auditory
    Language Spanish
    Publishing date 2023-05-05
    Publishing country Spain
    Document type Observational Study ; English Abstract ; Journal Article
    ZDB-ID 1468278-3
    ISSN 1576-6578 ; 0210-0010
    ISSN (online) 1576-6578
    ISSN 0210-0010
    DOI 10.33588/rn.7610.2023106
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  2. Article: Phenology and reproductive cycles in Mexican aphodiine dung beetles (Coleoptera: Scarabaeidae: Aphodiinae: Aphodiini)

    Martínez M., Imelda / Dellacasa, Marco / Lumaret, Jean-Pierre / Dellacasa, Giovanni

    Annales de la Société entomologique de France. 2022 Mar. 04, v. 58, no. 2

    2022  

    Abstract: The phenology and reproductive cycles of seven Mexican Aphodiini dung beetles are studied. The highest abundances of individuals occurred during the wet and warm season of the year, coinciding with the long summer. Their abundance is reduced or beetles ... ...

    Abstract The phenology and reproductive cycles of seven Mexican Aphodiini dung beetles are studied. The highest abundances of individuals occurred during the wet and warm season of the year, coinciding with the long summer. Their abundance is reduced or beetles are in diapause, depending on the species, during the dry and cold months that mainly corresponded to winter. Five species are univoltine, and females and males emerge mature after the first rains arrive, reproduce and then they enter diapause until the following year. One species is bivoltine and is found from the beginning of the wet season until the onset of winter. The other species is multivoltine and found almost all year round, although the highest abundances are found during the summer when generations overlap. The abundances of three of the species occurring at different localities are compared.
    Keywords Scarabaeidae ; cold ; diapause ; feces ; multivoltine habit ; phenology ; summer ; univoltine habit ; warm season ; wet season ; winter ; France
    Language English
    Dates of publication 2022-0304
    Size p. 173-185.
    Publishing place Taylor & Francis
    Document type Article
    ISSN 2168-6351
    DOI 10.1080/00379271.2022.2060859
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  3. Article ; Online: Patterns and outcomes of switching direct oral anticoagulants in non-valvular atrial fibrillation: A real-world experience from Spain.

    Rodilla, E / Orts-Martínez, M I / Sanz-Caballer, M A / Gimeno-Brosel, M T / Arilla-Morel, M J / Navarro-Gonzalo, I / Castillo-Valero, I / Salvador-Mercader, I / Carral-Tatay, A

    Revista clinica espanola

    2023  Volume 223, Issue 6, Page(s) 340–349

    Abstract: Aims: The aim is to evaluate a management program for direct oral anticoagulants (DOACs) in non-valvular atrial fibrillation (NVAF) patients according to their profiles, appropriateness of dosing, patterns of crossover, effectiveness and safety. This is ...

    Abstract Aims: The aim is to evaluate a management program for direct oral anticoagulants (DOACs) in non-valvular atrial fibrillation (NVAF) patients according to their profiles, appropriateness of dosing, patterns of crossover, effectiveness and safety. This is an observational and longitudinal prospective study in a cohort of patients attended in daily clinical practice in a regional hospital in Spain with 3-year a follow-up plan for patients initiating dabigatran, rivaroxaban or apixaban between JAN/2012-DEC/2016.
    Methods: We analyzed 490 episodes of treatment (apixaban 2.5 9.4%, apixaban 5 21.4%, dabigatran 75 0.6%, dabigatran 110 12,4%, dabigatran 150 19.8%, rivaroxaban 15 17.8% and rivaroxaban 20 18.6%) in 445 patients. 13.6% of patients on dabigatran, 9.7% on rivaroxaban, and 3.9% on apixaban switched to other DOACs or changed dosing.
    Results: Apixaban was the most frequent DOAC switched to. The most frequent reasons for switching were toxicity (23.8%), bleeding (21.4%) and renal deterioration (16.7%). Inappropriateness of dose was found in 23.8% of episodes. Rates of stroke/transient ischemic attack (TIA) were 1.64/0.54 events/100 patients-years, while rates of major, clinically relevant non-major (CRNM) bleeding and intracranial bleeding were 2.4, 5, and 0.5 events/100 patients-years. Gastrointestinal and genitourinary bleeding were the most common type of bleeding events (BE). On multivariable analysis, prior stroke and age were independent predictors of stroke/TIA. Concurrent platelet inhibitors, male gender and age were independent predictors of BE.
    Conclusion: This study complements the scant data available on the use of DOACs in NVAF patients in Spain, confirming a good safety and effectiveness profile.
    MeSH term(s) Humans ; Male ; Atrial Fibrillation/complications ; Atrial Fibrillation/drug therapy ; Atrial Fibrillation/chemically induced ; Rivaroxaban/adverse effects ; Dabigatran/adverse effects ; Anticoagulants/adverse effects ; Ischemic Attack, Transient/chemically induced ; Ischemic Attack, Transient/drug therapy ; Prospective Studies ; Spain ; Stroke/prevention & control ; Stroke/chemically induced ; Hemorrhage/chemically induced ; Hemorrhage/epidemiology ; Hemorrhage/drug therapy ; Retrospective Studies
    Chemical Substances Rivaroxaban (9NDF7JZ4M3) ; Dabigatran (I0VM4M70GC) ; Anticoagulants
    Language English
    Publishing date 2023-04-25
    Publishing country Spain
    Document type Observational Study ; Journal Article
    ISSN 2254-8874
    ISSN (online) 2254-8874
    DOI 10.1016/j.rceng.2023.04.005
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  4. Article: The Reproductive Biology of Euoniticellus intermedius (Reiche) (Coleoptera: Scarabaeinae: Oniticellini)

    Martínez-M., Imelda / Lumaret, Jean-Pierre / Martínez Diego, Ana Kory / Cano, Bulmaro Moreno

    Proceedings of the Entomological Society of Washington. 2019 Nov. 23, v. 121, no. 4

    2019  

    Abstract: The reproductive biology of Euoniticellus intermedius (Reiche) was studied using insects collected in Quiahuixtlan, Veracruz, Mexico, that were kept under controlled environmental conditions (temperature: 26.9 °C ± 0.09; relative humidity: 69.75% ± 1.7; ... ...

    Abstract The reproductive biology of Euoniticellus intermedius (Reiche) was studied using insects collected in Quiahuixtlan, Veracruz, Mexico, that were kept under controlled environmental conditions (temperature: 26.9 °C ± 0.09; relative humidity: 69.75% ± 1.7; photoperiod: 14D-10N). The reproductive systems of both sexes—similar to those described for other species of Scarabaeinae—are described. Females lay two eggs each day. Their fecundity is 111 ± 15 eggs. The lifespan of this species is 30 to 60 days. Development from egg to imago ranges from 25 to 28 days. The three larval instars are described.
    Keywords Euoniticellus intermedius ; eggs ; environmental factors ; fecundity ; females ; imagos ; insect larvae ; insects ; instars ; longevity ; relative humidity ; temperature ; Mexico
    Language English
    Dates of publication 2019-1123
    Size p. 642-656.
    Publishing place The Entomological Society of Washington
    Document type Article
    ZDB-ID 2533731-2
    ISSN 0013-8797
    ISSN 0013-8797
    DOI 10.4289/0013-8797.121.4.642
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  5. Article: Weather-based predictive models for Diaporthe helianthi ascospore release in Uruguay

    Moschini, R. C / Rodríguez, M. J / Martínez, M. I / Stewart, S

    Australasian plant pathology. 2019 Sept., v. 48, no. 5

    2019  

    Abstract: Stem canker (SC), caused by Diaporthe helianthi, is the most serious sunflower disease in Uruguay. Yield losses have been estimated up to 75%. Chemical control is one of the strategies used to manage this disease, but fungicide application should be done ...

    Abstract Stem canker (SC), caused by Diaporthe helianthi, is the most serious sunflower disease in Uruguay. Yield losses have been estimated up to 75%. Chemical control is one of the strategies used to manage this disease, but fungicide application should be done before symptoms are visible. Ascospores are the primary source of inoculum, they are produced in perithecia which develop in infected stubble and are dispersed by wind to infect plants. As in other monocyclic diseases, quantifying primary inoculum is essential to predict an epidemic. In this study, ascospores were trapped on microscope slides with solid petroleum jelly which were placed on top of flat open cages filled with natural infected stubble. Cages were placed outdoors, slides where replaced twice a week and stained ascospores were counted under the microscope. Our objective was to develop weather-based models to predict ascospore release levels of D. helianthi from infected stubble. Explanatory weather variables were calculated during the seven-day periods prior to each field weekly ascospore count using daily weather station data from La Estanzuela, Uruguay. Then, logistic models were fit to estimate probabilities of having severe or moderate to light levels of ascospore counts. The best models included variables associated to the precipitation and dew-induced wetness frequency, combinated with the simultaneous occurrence of high relative humidity or low thermal amplitude records. Estimating the evolution of ascospore release through the weather-based models might help to guide preventive fungicide applications to control stem canker in Uruguay.
    Keywords Diaporthe helianthi ; Helianthus annuus ; anemochory ; ascospores ; cages ; chemical control ; fungicide application ; fungicides ; inoculum ; logit analysis ; models ; perithecia ; petrolatum ; probability ; relative humidity ; stem cankers ; stubble ; Uruguay
    Language English
    Dates of publication 2019-09
    Size p. 519-527.
    Publishing place Springer Netherlands
    Document type Article
    ZDB-ID 406733-2
    ISSN 1448-6032 ; 0815-3191
    ISSN (online) 1448-6032
    ISSN 0815-3191
    DOI 10.1007/s13313-019-00655-x
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  6. Article ; Online: Site-bond percolation solution to preventing the propagation of Phytophthora zoospores on plantations.

    Ramírez, J E / Pajares, C / Martínez, M I / Rodríguez Fernández, R / Molina-Gayosso, E / Lozada-Lechuga, J / Fernández Téllez, A

    Physical review. E

    2020  Volume 101, Issue 3-1, Page(s) 32301

    Abstract: We propose a strategy based on the site-bond percolation to minimize the propagation of Phytophthora zoospores on plantations, consisting in introducing physical barriers between neighboring plants. Two clustering processes are distinguished: (i) one of ... ...

    Abstract We propose a strategy based on the site-bond percolation to minimize the propagation of Phytophthora zoospores on plantations, consisting in introducing physical barriers between neighboring plants. Two clustering processes are distinguished: (i) one of cells with the presence of the pathogen, detected on soil analysis, and (ii) that of diseased plants, revealed from a visual inspection of the plantation. The former is well described by the standard site-bond percolation. In the latter, the percolation threshold is fitted by a Tsallis distribution when no barriers are introduced. We provide, for both cases, the formulas for the minimal barrier density to prevent the emergence of the spanning cluster. Though this work is focused on a specific pathogen, the model presented here can also be applied to prevent the spreading of other pathogens that disseminate, by other means, from one plant to the neighboring ones. Finally, the application of this strategy to three types of commercially important Mexican chili plants is also shown.
    Language English
    Publishing date 2020-04-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2844562-4
    ISSN 2470-0053 ; 2470-0045
    ISSN (online) 2470-0053
    ISSN 2470-0045
    DOI 10.1103/PhysRevE.101.032301
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  7. Article: Efecto de la temperatura y la salinidad en el ciclo reproductor de hembras y machos de Crassostrea virginica (Bivalvia: Ostreidae).

    Ascencio A, Luis Alfonso / Enrεquez D, Martha / Martínez M, Imelda / Aldana A, Dalila

    Revista de biologia tropical

    2018  Volume 64, Issue 2, Page(s) 449–459

    Title translation Effect of temperature and salinity on the reproductive cycle of males and females of Crassostrea virginica (Bivalvia: Ostreidae).
    MeSH term(s) Animals ; Crassostrea/classification ; Crassostrea/physiology ; Female ; Male ; Reproduction/physiology ; Salinity ; Seasons ; Temperature
    Language Spanish
    Publishing date 2018-02-16
    Publishing country Costa Rica
    Document type Journal Article
    ZDB-ID 2020929-0
    ISSN 2215-2075 ; 0034-7744
    ISSN (online) 2215-2075
    ISSN 0034-7744
    DOI 10.15517/rbt.v64i2.18137
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  8. Article ; Online: Trans-generational effects of ivermectin exposure in dung beetles.

    Baena-Díaz, Fernanda / Martínez-M, Imelda / Gil-Pérez, Yorleny / González-Tokman, Daniel

    Chemosphere

    2018  Volume 202, Page(s) 637–643

    Abstract: Ivermectin is a powerful antiparasitic drug commonly used in cattle. Ivermectin residues are excreted in dung, threatening non-target coprophagous fauna such as dung beetles. This can have severe ecological and economic consequences for dung degradation ... ...

    Abstract Ivermectin is a powerful antiparasitic drug commonly used in cattle. Ivermectin residues are excreted in dung, threatening non-target coprophagous fauna such as dung beetles. This can have severe ecological and economic consequences for dung degradation and soil fertility. Even though the negative effects of direct ivermectin exposure on dung-degrading organisms are well known, effects could extend across generations. Here, we tested the effects of paternal or maternal exposure to ivermectin on offspring in the dung beetle Euoniticellus intermedius. This species is a classic study subject in ecotoxicology and sexual selection because males have a cephalic horn that is under intense selection via male-male competition. After confirming a negative effect of ivermectin on the number of emerged beetles, we found trans-generational effects of ivermectin exposure on the horn size of male offspring. Surprisingly however, this trans-generational effect only occurred when only the father was exposed. We detected no trans-generational effects of ivermectin exposure on offspring number, sex ratio or body size. Our results confirm that ivermectin not only has a strong effect on exposed individuals but also in their progeny. Our study opens new questions about the mechanisms responsible for parental effects and their long-term fitness consequences in contaminated habitats.
    MeSH term(s) Animals ; Antiparasitic Agents/pharmacology ; Body Size/drug effects ; Cattle ; Coleoptera/drug effects ; Coleoptera/growth & development ; Ecotoxicology ; Feces/parasitology ; Female ; Fertility/drug effects ; Ivermectin/pharmacology ; Life Cycle Stages/drug effects ; Male ; Phenotype ; Reproduction ; Sex Ratio
    Chemical Substances Antiparasitic Agents ; Ivermectin (70288-86-7)
    Language English
    Publishing date 2018-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2018.03.109
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  9. Article: [Randomized experimental study to evaluate the effectiveness of the Flebitis Zero project in Navarre].

    Ferraz-Torres, M / Corcuera Martínez, M I / Sancho Sena, E / Aldonza-Torres, M / Maali Centeno, S / Martínez-Ortega, M C / Suárez-Mier, M B

    Anales del sistema sanitario de Navarra

    2021  Volume 44, Issue 3, Page(s) 417–426

    Abstract: Background: Phlebitis is one of the most frequent complications in peripheral venous catheters. The aim was to compare the frequency of phlebitis before and after the implementation of the Flebitis Zero project, in order to ascertain its effectiveness ... ...

    Abstract Background: Phlebitis is one of the most frequent complications in peripheral venous catheters. The aim was to compare the frequency of phlebitis before and after the implementation of the Flebitis Zero project, in order to ascertain its effectiveness and what factors were associated with this complication.
    Methods: Randomized pre-post intervention (Flebitis Zero project) study performed in the Hospital Universitario de Navarra (Pamplona, Spain) between 2015 and 2019. The intervention consisted of training of professionals along with the implementation of measures in order to lower the incidence of complications associated with the peripheral venous catheters. The control group (CG) was selected prior the intervention and the Intervention Group (IG) in the subsequent five years.
    Results: The study included 656 patients, 96 (14.6%) in the CG and 569 in the IG. Lower frequency of complications (49.0 vs 37.1%; p<0.001), especially accidental PVC exit (18.8 vs 8.1%), and of phlebitis (13.5 vs 11.8%). The intervention and the use of fully reinforced dressings were associated to happening of phlebitis. The implantation of the Flebitis Zero project prevented the occurrence of phlebitis (OR = 0.78; IC95%: 0.42-0.86; p = 0.042).
    Conclusion: The implementation of the measures used in the Phlebitis Zero project was associated with a significant reduction of the complications linked to the use of the peripheral venous catheters; the frequency of phlebitis dropped, although nowhere near the recommended level.
    MeSH term(s) Catheterization, Peripheral/adverse effects ; Humans ; Incidence ; Phlebitis/epidemiology ; Phlebitis/etiology ; Phlebitis/prevention & control ; Spain/epidemiology
    Language Spanish
    Publishing date 2021-12-27
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 2141772-6
    ISSN 1137-6627
    ISSN 1137-6627
    DOI 10.23938/ASSN.0975
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  10. Article ; Online: Percolation-intercropping strategies to prevent dissemination of phytopathogens on plantations.

    Rosales Herrera, Diana / Ramírez, J E / Martínez, M I / Cruz-Suárez, H / Fernández Téllez, A / López-Olguín, Jesús F / Aragón García, Agustín

    Chaos (Woodbury, N.Y.)

    2021  Volume 31, Issue 6, Page(s) 63105

    Abstract: Phytophthora is one of the most aggressive and worldwide extended phytopathogens that attack plants and trees. Its effects produce tremendous economical losses in agronomy and forestry since no effective fungicide exists. We propose to combine ... ...

    Abstract Phytophthora is one of the most aggressive and worldwide extended phytopathogens that attack plants and trees. Its effects produce tremendous economical losses in agronomy and forestry since no effective fungicide exists. We propose to combine percolation theory with an intercropping sowing configuration as a non-chemical strategy to minimize the dissemination of the pathogen. In this work, we model a plantation as a square lattice where two types of plants are arranged in alternating columns or diagonals, and Phytophthora zoospores are allowed to propagate to the nearest and next-to-nearest neighboring plants. We determine the percolation threshold for each intercropping configuration as a function of the plant's susceptibilities and the number of inoculated cells at the beginning of the propagation process. The results are presented as phase diagrams where crop densities that prevent the formation of a spanning cluster of susceptible or diseased plants are indicated. The main result is the existence of susceptibility value combinations for which no spanning cluster is formed even if every cell in the plantation is sowed. This finding can be useful in choosing a configuration and density of plants that minimize damages caused by Phytophthora. We illustrate the application of the phase diagrams with the susceptibilities of three plants with a high commercial value.
    MeSH term(s) Agriculture ; Trees
    Language English
    Publishing date 2021-07-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1472677-4
    ISSN 1089-7682 ; 1054-1500
    ISSN (online) 1089-7682
    ISSN 1054-1500
    DOI 10.1063/5.0044714
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