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  1. Article: Groove pancreatitis: a rare cause of severe gastric dilation.

    Martínez de la Cruz, Paula / Riado Mínguez, Daniel / Martel Villagrán, José / Verdejo Gil, Cristina

    Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva

    2020  Volume 112, Issue 11, Page(s) 879–880

    Abstract: A 57-year-old male with a history of chronic pancreatitis related to heavy smoking and alcohol abuse was evaluated in the emergency department due to a 3-day history of epigastric pain and postprandial vomiting. Abdominal computed tomography (CT) was ... ...

    Abstract A 57-year-old male with a history of chronic pancreatitis related to heavy smoking and alcohol abuse was evaluated in the emergency department due to a 3-day history of epigastric pain and postprandial vomiting. Abdominal computed tomography (CT) was performed and revealed a severe gastric dilation that reached the pelvis. There was a marked concentric mural thickening at the duodenal level and an intramural cysts that caused a narrowing of the light and a retrograde gastric dilation. There were no findings suggestive of chronic pancreatitis. A diagnosis was made of duodenal obstruction due to groove pancreatitis with severe secondary gastric dilatation.
    MeSH term(s) Duodenum ; Gastric Dilatation/diagnostic imaging ; Gastric Dilatation/etiology ; Humans ; Male ; Middle Aged ; Pancreatitis, Chronic/complications ; Pancreatitis, Chronic/diagnostic imaging ; Tomography, X-Ray Computed
    Language English
    Publishing date 2020-10-15
    Publishing country Spain
    Document type Case Reports ; Journal Article
    ZDB-ID 1070381-0
    ISSN 1130-0108 ; 0212-7512
    ISSN 1130-0108 ; 0212-7512
    DOI 10.17235/reed.2020.6765/2019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Concomitant Acute Tubular Necrosis and Acute Interstitial Nephritis Induced by Tipifarnib in a Patient with Squamous Cell Carcinoma of the Lung.

    Martinez de la Cruz, Paula / Shabaka, Amir / Mielgo-Rubio, Xabier / Guerrero-Marquez, Carmen / Gimenez-Moyano, Sara / Fernandez-Juarez, Gema

    The American journal of the medical sciences

    2021  Volume 362, Issue 1, Page(s) 99–102

    Abstract: Tipifarnib is a novel targeted treatment for hematologic malignancies that is being recently studied for the treatment of advanced solid organ tumors with HRAS mutations. There have been scarce reports on kidney adverse events in initial phase I and II ... ...

    Abstract Tipifarnib is a novel targeted treatment for hematologic malignancies that is being recently studied for the treatment of advanced solid organ tumors with HRAS mutations. There have been scarce reports on kidney adverse events in initial phase I and II trials. We present a case of acute kidney injury in a patient that had started treatment with tipifarnib for advanced squamous cell carcinoma of the lung. Kidney biopsy revealed acute tubular necrosis together with acute interstitial nephritis. Tipifarnib was discontinued and the patient was started with high-dose corticosteroids with an early taper completing a five-week steroid course, with full recovery of kidney function.
    MeSH term(s) Aged ; Antineoplastic Agents/adverse effects ; Carcinoma, Squamous Cell/diagnosis ; Carcinoma, Squamous Cell/drug therapy ; Humans ; Kidney Cortex Necrosis/chemically induced ; Kidney Cortex Necrosis/complications ; Kidney Cortex Necrosis/diagnosis ; Lung Neoplasms/diagnosis ; Lung Neoplasms/drug therapy ; Male ; Nephritis, Interstitial/chemically induced ; Nephritis, Interstitial/complications ; Nephritis, Interstitial/diagnosis ; Quinolones/adverse effects
    Chemical Substances Antineoplastic Agents ; Quinolones ; tipifarnib (MAT637500A)
    Language English
    Publishing date 2021-04-16
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 82078-7
    ISSN 1538-2990 ; 0002-9629
    ISSN (online) 1538-2990
    ISSN 0002-9629
    DOI 10.1016/j.amjms.2021.04.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: Antibiotic discontinuation through an antibiotic treatment optimization program in emergency department patients with low suspicion of infection.

    Martínez-de la Cruz, Paula / Moreno-Núñez, Leonor / Álvarez-Atienza, Sara / Sanz-Márquez, Sira / Valverde-Canovas, José Francisco / Losa-García, Juan Emilio

    Enfermedades infecciosas y microbiologia clinica (English ed.)

    2022  Volume 41, Issue 7, Page(s) 423–425

    Abstract: Introduction: One of the most important strategies of PROA in the Emergency Department (ED) is the accurate diagnosis of infection to avoid inappropriate prescription. Our objective is to evaluate patients who receive antibiotics despite not having ... ...

    Abstract Introduction: One of the most important strategies of PROA in the Emergency Department (ED) is the accurate diagnosis of infection to avoid inappropriate prescription. Our objective is to evaluate patients who receive antibiotics despite not having objective data of infection.
    Methods: We carried out a cross-sectional study of patients admitted to the ED of the Hospital Universitario Fundación Alcorcón in which it was recommended to suspend the antibiotic through the PROA. Clinical and epidemiological characteristics and 30-day follow-up were analyzed to assess readmissions and mortality.
    Results: 145 patients were analyzed. It was recommended to suspend the antibiotic in 25. 44% of them had a diagnosis of urinary infection. The suspension recommendation was accepted by 88%. No patient died and one was readmitted.
    Conclusions: An important percentage of patients are prescribed antibiotics despite not having infection criteria, the clinical evolution after suspension of antibiotics was favorable.
    Language English
    Publishing date 2022-11-06
    Publishing country Spain
    Document type Journal Article
    ISSN 2529-993X
    ISSN (online) 2529-993X
    DOI 10.1016/j.eimce.2022.10.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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