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  1. Article ; Online: Hypoxic-ischaemic encephalopathy code: A systematic review for resource-limited settings.

    Garcia-Alix, Alfredo / Arnaez, Juan / Arca, Gemma / Martinez-Biarge, Miriam

    Anales de pediatria

    2024  Volume 100, Issue 4, Page(s) 275–286

    Abstract: It is estimated that 96% of infants with hypoxic-ischaemic encephalopathy (HIE) are born in resource-limited settings with no capacity to provide the standard of care that has been established for nearly 15 years in high-resource countries, which ... ...

    Abstract It is estimated that 96% of infants with hypoxic-ischaemic encephalopathy (HIE) are born in resource-limited settings with no capacity to provide the standard of care that has been established for nearly 15 years in high-resource countries, which includes therapeutic hypothermia (TH), continuous electroencephalographic monitoring and magnetic resonance imaging (MRI) in addition to close vital signs and haemodynamic monitoring. This situation does not seem to be changing; however, even with these limitations, currently available knowledge can help improve the care of HIE patients in resource-limited settings. The purpose of this systematic review was to provide, under the term "HIE Code", evidence-based recommendations for feasible care practices to optimise the care of infants with HIE and potentially help reduce the risks associated with comorbidity and improve neurodevelopmental outcomes. The content of the HIE code was grouped under 9 headings: (1) prevention of HIE, (2) resuscitation, (3) first 6h post birth, (4) identification and grading of encephalopathy, (5) seizure management, (6) other therapeutic interventions, (7) multiple organ dysfunction, (8) diagnostic tests and (9) family care.
    MeSH term(s) Humans ; Hypoxia-Ischemia, Brain/therapy ; Hypoxia-Ischemia, Brain/diagnosis ; Infant, Newborn ; Developing Countries ; Hypothermia, Induced/methods ; Health Resources ; Electroencephalography ; Resource-Limited Settings
    Language English
    Publishing date 2024-04-12
    Publishing country Spain
    Document type Systematic Review ; Journal Article
    ZDB-ID 2830901-7
    ISSN 2341-2879 ; 2341-2879
    ISSN (online) 2341-2879
    ISSN 2341-2879
    DOI 10.1016/j.anpede.2024.04.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The predictive role of brain magnetic resonance imaging in neonates with hypoxic-ischemic encephalopathy.

    Cizmeci, Mehmet N / Martinez-Biarge, Miriam / Cowan, Frances M

    Pediatric research

    2023  Volume 95, Issue 3, Page(s) 601–602

    MeSH term(s) Infant, Newborn ; Humans ; Hypoxia-Ischemia, Brain/therapy ; Magnetic Resonance Imaging/methods ; Brain/diagnostic imaging ; Brain/pathology ; Head ; Hypothermia, Induced
    Language English
    Publishing date 2023-07-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 4411-8
    ISSN 1530-0447 ; 0031-3998
    ISSN (online) 1530-0447
    ISSN 0031-3998
    DOI 10.1038/s41390-023-02732-w
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 564: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 373: Show issues

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  3. Article ; Online: Motor, cognitive and behavioural outcomes after neonatal hypoxic-ischaemic encephalopathy.

    Hortigüela, María Montesclaros / Martínez-Biarge, Miriam / Conejo, David / Vega-Del-Val, Cristina / Arnaez, Juan

    Anales de pediatria

    2024  Volume 100, Issue 2, Page(s) 104–114

    Abstract: Introduction: The current neurodevelopmental status of patients with neonatal hypoxic-ischaemic encephalopathy (HIE) in Spain is unknown. Recent European studies highlight a shift of severe pathology towards mild motor disorders and emotional problems. ... ...

    Abstract Introduction: The current neurodevelopmental status of patients with neonatal hypoxic-ischaemic encephalopathy (HIE) in Spain is unknown. Recent European studies highlight a shift of severe pathology towards mild motor disorders and emotional problems. The aim of this study was to analyse neurodevelopmental outcomes in a cohort of neonates with HIE at age 3 years.
    Patients and method: Multicentre observational study of neonates born at 35 or more weeks of gestation with moderate to severe HIE in 2011-2013 in 12 hospitals in a large Spanish region (91 217 m
    Results: Sixty-three patients were recruited, of whom 5 (7.9%) were excluded due to other pathology and 14 (24%) died. Of the 44 survivors, 42 (95.5%) were evaluated. Of these 42, 10 (24%) had adverse outcomes (visual or hearing impairment, epilepsy, cerebral palsy or developmental delay). Other detected problems were minor neurological signs in 6 of the 42 (14%) and a higher incidence of emotional problems compared to controls: introversion (10.5% vs. 1.3%), anxiety (34.2% vs. 11.7%) and depression (28.9% vs. 7.8%) (P < .05). The severity of the lesions on neuroimaging was significantly higher in patients with motor impairment (P = .004) or who died or had an adverse outcome (P = .027).
    Conclusion: In addition to classical sequelae, the followup of patients with neonatal HIE should include the diagnosis and treatment of minor motor disorders and social and emotional problems.
    MeSH term(s) Child, Preschool ; Humans ; Infant, Newborn ; Asphyxia Neonatorum ; Cognition ; Cognitive Dysfunction ; Hypoxia-Ischemia, Brain/therapy ; Parturition
    Language English
    Publishing date 2024-02-07
    Publishing country Spain
    Document type Journal Article ; Multicenter Study ; Observational Study
    ZDB-ID 2830901-7
    ISSN 2341-2879 ; 2341-2879
    ISSN (online) 2341-2879
    ISSN 2341-2879
    DOI 10.1016/j.anpede.2024.01.009
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  4. Article ; Online: The Hammersmith Infant Neurological Examination: Concern about low scores in typically developing infants born at term.

    Vollmer, Brigitte / Martinez-Biarge, Miriam / Romeo, Domenico M

    The Journal of pediatrics

    2022  Volume 246, Page(s) 286–287

    MeSH term(s) Humans ; Infant ; Infant, Newborn ; Infant, Premature ; Infant, Premature, Diseases ; Neurologic Examination
    Language English
    Publishing date 2022-03-28
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2022.03.047
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    In stock of ZB MED Cologne/Königswinter

    Um IV Zs.116: Show issues Location:
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  5. Article ; Online: Questions about the HELIX trial.

    Aker, Karoline / Støen, Ragnhild / Martinez-Biarge, Miriam / Thomas, Niranjan

    The Lancet. Global health

    2021  Volume 9, Issue 12, Page(s) e1651

    Language English
    Publishing date 2021-11-19
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2723488-5
    ISSN 2214-109X ; 2214-109X
    ISSN (online) 2214-109X
    ISSN 2214-109X
    DOI 10.1016/S2214-109X(21)00496-4
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  6. Article: Perinatal arterial ischemic stroke.

    Martinez-Biarge, Miriam / Ferriero, Donna M / Cowan, Frances M

    Handbook of clinical neurology

    2019  Volume 162, Page(s) 239–266

    Abstract: Perinatal arterial ischemic stroke is a relatively common and serious neurologic disorder that can affect the fetus, the preterm, and the term-born infant. It carries significant long-term disabilities. Herein we describe the current understanding of its ...

    Abstract Perinatal arterial ischemic stroke is a relatively common and serious neurologic disorder that can affect the fetus, the preterm, and the term-born infant. It carries significant long-term disabilities. Herein we describe the current understanding of its etiology, pathophysiology and classification, different presentations, and optimal early management. We discuss the role of different brain imaging modalities in defining the extent of lesions and the impact this has on the prediction of outcomes. In recent years there has been progress in treatments, making early diagnosis and the understanding of likely morbidities imperative. An overview is given of the range of possible outcomes and optimal approaches to follow-up and support for the child and their family in the light of present knowledge.
    MeSH term(s) Adult ; Animals ; Brain Ischemia/congenital ; Brain Ischemia/diagnosis ; Brain Ischemia/diagnostic imaging ; Brain Ischemia/therapy ; Female ; Humans ; Infant, Newborn ; Infant, Newborn, Diseases/diagnosis ; Infant, Newborn, Diseases/diagnostic imaging ; Infant, Newborn, Diseases/therapy ; Neuroimaging ; Pregnancy ; Stroke/congenital ; Stroke/diagnosis ; Stroke/diagnostic imaging ; Stroke/therapy
    Language English
    Publishing date 2019-07-19
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 0072-9752
    ISSN 0072-9752
    DOI 10.1016/B978-0-444-64029-1.00011-4
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  7. Article ; Online: Lack of supplementation, and not a vegan diet, as a cause of rickets in an infant.

    Martinez-Biarge, Miriam / Gould, Samantha / Alcalde de Alvaré, Ana Dolores / Marques-Lopes, Iva

    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie

    2021  Volume 28, Issue 3, Page(s) 255–256

    MeSH term(s) Diet, Vegan ; Dietary Supplements ; Humans ; Infant ; Rickets/diagnosis ; Rickets/etiology ; Vitamin D Deficiency/complications
    Language English
    Publishing date 2021-03-02
    Publishing country France
    Document type Letter ; Comment
    ZDB-ID 1181947-9
    ISSN 1769-664X ; 0929-693X
    ISSN (online) 1769-664X
    ISSN 0929-693X
    DOI 10.1016/j.arcped.2020.12.012
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3942: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  8. Article ; Online: Seguimiento a medio-largo plazo de los niños prematuros y sus familias en nuestro país.

    Loureiro, Begoña / Agut, Thais / Boronat, Nuria / Martínez-Biarge, Miriam

    Anales de pediatria

    2019  Volume 91, Issue 3, Page(s) 139–141

    Title translation Medium to long-term follow-up of premature children and their families in Spain.
    MeSH term(s) Aftercare/methods ; Humans ; Infant, Newborn ; Infant, Newborn, Diseases/therapy ; Infant, Premature ; Infant, Premature, Diseases/therapy ; Spain ; Time Factors
    Language Spanish
    Publishing date 2019-06-29
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 2830901-7
    ISSN 2341-2879 ; 2341-2879
    ISSN (online) 2341-2879
    ISSN 2341-2879
    DOI 10.1016/j.anpedi.2019.06.002
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  9. Article ; Online: Preterm white matter injury: ultrasound diagnosis and classification.

    Agut, Thais / Alarcon, Ana / Cabañas, Fernando / Bartocci, Marco / Martinez-Biarge, Miriam / Horsch, Sandra

    Pediatric research

    2020  Volume 87, Issue Suppl 1, Page(s) 37–49

    Abstract: White matter injury (WMI) is the most frequent form of preterm brain injury. Cranial ultrasound (CUS) remains the preferred modality for initial and sequential neuroimaging in preterm infants, and is reliable for the diagnosis of cystic periventricular ... ...

    Abstract White matter injury (WMI) is the most frequent form of preterm brain injury. Cranial ultrasound (CUS) remains the preferred modality for initial and sequential neuroimaging in preterm infants, and is reliable for the diagnosis of cystic periventricular leukomalacia. Although magnetic resonance imaging is superior to CUS in detecting the diffuse and more subtle forms of WMI that prevail in very premature infants surviving nowadays, recent improvement in the quality of neonatal CUS imaging has broadened the spectrum of preterm white matter abnormalities that can be detected with this technique. We propose a structured CUS assessment of WMI of prematurity that seeks to account for both cystic and non-cystic changes, as well as signs of white matter loss and impaired brain growth and maturation, at or near term equivalent age. This novel assessment system aims to improve disease description in both routine clinical practice and clinical research. Whether this systematic assessment will improve prediction of outcome in preterm infants with WMI still needs to be evaluated in prospective studies.
    MeSH term(s) Brain/diagnostic imaging ; Brain Injuries/diagnostic imaging ; Echoencephalography/methods ; Humans ; Infant ; Infant, Newborn ; Infant, Premature ; Infant, Premature, Diseases/diagnostic imaging ; Leukomalacia, Periventricular/diagnostic imaging ; Magnetic Resonance Imaging ; Neonatology/methods ; Predictive Value of Tests ; White Matter/diagnostic imaging
    Language English
    Publishing date 2020-03-26
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 4411-8
    ISSN 1530-0447 ; 0031-3998
    ISSN (online) 1530-0447
    ISSN 0031-3998
    DOI 10.1038/s41390-020-0781-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 564: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 373: Show issues

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  10. Article ; Online: Developing a Food Exchange System for Meal Planning in Vegan Children and Adolescents.

    Menal-Puey, Susana / Martínez-Biarge, Miriam / Marques-Lopes, Iva

    Nutrients

    2018  Volume 11, Issue 1

    Abstract: Vegan diets in children need to be adequately planned so they can safely meet children's requirements for growth and development. Adequate and realistic meal planning guidelines should not be difficult to achieve, thanks to the increasing number and ... ...

    Abstract Vegan diets in children need to be adequately planned so they can safely meet children's requirements for growth and development. Adequate and realistic meal planning guidelines should not be difficult to achieve, thanks to the increasing number and availability of natural and fortified vegan foods, which can help children to meet all their nutrients requirements. In order to ensure an adequate supply of key nutrients, families and health professionals need accurate, reliable, and easy-to-use meal planning tools. The aim of this article is to provide a practical approach system to meal planning, based on the same food exchange methodology that has been already published in adults. Daily portions of each food exchange group have been calculated so the resulting menu provides at least 90% of the Dietary Reference Intakes (DRIs) of protein, iron, zinc, calcium, and n-3 fatty acids for each age group, sex, and physical activity level. These diets do not provide enough vitamin B-12 and vitamin D. Although fortified plant drinks, breakfast cereals or plant protein-rich products could provide variable amounts of these two vitamins, B12 supplementation is always recommended and vitamin D supplementation should be considered whenever sun exposure is limited. This tool can be used to plan healthful and balanced vegan diets for children and adolescents.
    MeSH term(s) Adolescent ; Child ; Child Nutritional Physiological Phenomena ; Diet, Vegan ; Dietary Fats ; Dietary Fiber ; Dietary Proteins ; Female ; Food/classification ; Humans ; Male ; Meals ; Nutritional Requirements ; Vegans
    Chemical Substances Dietary Fats ; Dietary Fiber ; Dietary Proteins
    Language English
    Publishing date 2018-12-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu11010043
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