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  1. Article ; Online: Catatonia associated with pediatric postoperative cerebellar mutism syndrome.

    Jaimes-Albornoz, Walter / Wu, Peter / de Mendaza-Martínez de Icaya, Lydia García / Rozali, Farah / Martínez-Querol, María / Smith, Rowena / Isetta, Marco / de Pellón Santamaria, Ángel Ruiz / Serra-Mestres, Jordi

    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

    2024  

    Abstract: Objective: To ascertain the presence of catatonia in cases of pediatric postoperative cerebellar mutism syndrome (PPCMS).: Method: A systematic review of PPCMS case reports of patients aged 0-17 years with sufficient clinical information to extract ... ...

    Abstract Objective: To ascertain the presence of catatonia in cases of pediatric postoperative cerebellar mutism syndrome (PPCMS).
    Method: A systematic review of PPCMS case reports of patients aged 0-17 years with sufficient clinical information to extract catatonic phenomena was undertaken following PRISMA guidelines. Standardized catatonia rating scales were applied to selected cases retrospectively to ascertain whether diagnostic criteria for catatonia were met. A case known to the authors is also presented.
    Results: Two hundred twenty-one suitable full-text articles were identified. Following screening and application of inclusion criteria, 51 articles were selected plus seven more from their references, reporting on 119 subjects. All cases met Bush and Francis (BF) diagnostic criteria for catatonia, 92.5% Pediatric Catatonia Rating Scale (PCRS), 52.9% ICD-11, and 44.5% DSM-5. All patients presented with mutism. The next most frequent signs were immobility/stupor (77.3%), withdrawal (35.3%), mannerisms (23.5%), and excitement/agitation (18.5%). Most cases presented with stuporous catatonia (75.6%). Catatonia most frequently occurred following resection of medulloblastoma (64.7%). Preoperative hydrocephalus occurred in 89 patients (74.8%).
    Conclusion: Catatonia was frequent in this PPCMS sample, with a predominant stuporous variant; it should be considered in patients with PPCMS and assessed with reliable and validated instruments for prompt diagnosis and management.
    Language English
    Publishing date 2024-04-17
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 605988-0
    ISSN 1433-0350 ; 0302-2803 ; 0256-7040
    ISSN (online) 1433-0350
    ISSN 0302-2803 ; 0256-7040
    DOI 10.1007/s00381-024-06392-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Prolactin and morning cortisol concentrations in antipsychotic naïve first episode psychosis: A systematic review and meta-analysis.

    Aymerich, Claudia / Pedruzo, Borja / Pacho, Malein / Laborda, María / Herrero, Jon / Pillinger, Toby / McCutcheon, Robert A / Alonso-Alconada, Daniel / Bordenave, Marta / Martínez-Querol, Maria / Arnaiz, Ainara / Labad, Javier / Fusar-Poli, Paolo / González-Torres, Miguel Ángel / Catalan, Ana

    Psychoneuroendocrinology

    2023  Volume 150, Page(s) 106049

    Abstract: Importance: Alterations in prolactin and cortisol levels have been reported in antipsychotic naïve patients with first episode psychosis (FEP). However, it has been studied in very small samples, and inter-group variability has never been studied before. ...

    Abstract Importance: Alterations in prolactin and cortisol levels have been reported in antipsychotic naïve patients with first episode psychosis (FEP). However, it has been studied in very small samples, and inter-group variability has never been studied before.
    Objective: To provide estimates of standardized mean differences (SMD) and inter-group variability for prolactin, cortisol awakening response (CAR) and morning cortisol concentrations in antipsychotic naïve FEP (AN-FEP) patients and healthy controls (HC).
    Data sources: BIOSIS, KCI, MEDLINE, Russian Science Citation Index, SciELO, Cochrane, PsycINFO, Web of Science were searched from inception to February 28, 2022.
    Study selection: Peer-reviewed cohort studies that reported on prolactin or cortisol blood concentrations in AN- FEP patients and HC were included.
    Data extraction and synthesis: Study characteristics, means and standard deviations (SD) were extracted from each article. Inter group differences in magnitude of effect were estimated using Hedges g. Inter-group variability was estimated with the coefficient of variation ratio (CVR). In both cases estimates were pooled using random-effects meta-analysis. Differences by study-level characteristics were estimated using meta-regression. PRISMA guideline was followed (No. CRD42022303555).
    Main outcomes and measures: Prolactin, CAR and morning cortisol blood concentrations in AN-FEP group in relation to HC group.
    Results: Fourteen studies for prolactin (N = 761 for AN-FEP group, N = 687 for HC group) and twelve studies for morning cortisol (N = 434 for AN-FEP group, N = 528 for HC group) were included. No studies were found in CAR in AN-FEP patients. Mean SMD for prolactin blood concentration was 0.88 (95% CI 0.57, 1.20) for male and 0.56 (95% CI 0.26, 0.87) for female. As a group, AN-FEP presented greater inter-group variability for prolactin levels than HC (CVR=1.28, 95% CI 1.02, 1.62). SMD for morning cortisol concentrations was non-significant: 0.34 (95% CI -0.01, 0.69) and no inter-group variability significant differences were detected: CVR= 1.05 (95% CI 0.91, 1.20). Meta-regression analyses for age and quality were non-significant. Funnel plots did not suggest a publication bias.
    Conclusions and relevance: Increased prolactin levels were found in AN-FEP patients. A greater inter-group variability in the AN-FEP group suggests the existence of patient subgroups with different prolactin levels. No significant abnormalities were found in morning cortisol levels. Further research is needed to clarify whether prolactin concentrations could be used as an illness biomarker.
    MeSH term(s) Humans ; Male ; Female ; Prolactin ; Schizophrenia ; Antipsychotic Agents ; Hydrocortisone ; Psychotic Disorders
    Chemical Substances Prolactin (9002-62-4) ; Antipsychotic Agents ; Hydrocortisone (WI4X0X7BPJ)
    Language English
    Publishing date 2023-02-04
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 197636-9
    ISSN 1873-3360 ; 0306-4530
    ISSN (online) 1873-3360
    ISSN 0306-4530
    DOI 10.1016/j.psyneuen.2023.106049
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Voices 2: Improving Prosodic Recognition in Schizophrenia With an Online Rehabilitation Program.

    Lado-Codesido, María / Rey Varela, Rosa María / Larios Quiñones, Marina / Martínez Agulleiro, Luis / Ossa Basanes, Julieta / Martínez Querol, María / Mateos, Raimundo / Spuch, Carlos / García-Caballero, Alejandro

    Frontiers in psychology

    2021  Volume 12, Page(s) 739252

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2021-12-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2021.739252
    Database MEDical Literature Analysis and Retrieval System OnLINE

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