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  1. Article ; Online: Reply to Gan

    Martinez, Fernando J

    American journal of respiratory and critical care medicine

    2023  Volume 208, Issue 10, Page(s) 1141–1142

    Language English
    Publishing date 2023-09-25
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202309-1653LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: Asthma in the Time of COVID-19.

    Martinez, Fernando D

    American journal of respiratory and critical care medicine

    2021  Volume 203, Issue 7, Page(s) 785–786

    MeSH term(s) Asthma/epidemiology ; Biomedical Research/statistics & numerical data ; COVID-19/epidemiology ; Humans ; Pandemics/statistics & numerical data ; Periodicals as Topic/statistics & numerical data ; Research Report ; SARS-CoV-2 ; United States
    Language English
    Publishing date 2021-02-17
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202102-0389ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Book: Special issue: Structure and function of soil and soil cover in a changing world

    Martín, Miguel Angel / Martínez, Fernando San José / Perfect, Edmund / Lado, Marcos / Pachepsky, Yakov

    characterization and scaling

    (Geoderma ; Volume 287 (1 February 2017))

    2017  

    Author's details edited by Miguel Ángel Martin, Fernando San José Martínez, Edmund Perfect, Marcos Lado and Yakov Pachepsky
    Series title Geoderma ; Volume 287 (1 February 2017)
    Collection
    Language English
    Size 116 Seiten, Illustrationen
    Publisher Elsevier
    Publishing place Amsterdam
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT019205469
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    Z 2363 (287) available for loan (reading room) Freihandmagazin (U1)

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  4. Article ; Online: The State of Asthma Research: Considerable Advances, but Still a Long Way to Go.

    Martinez, Fernando D

    American journal of respiratory and critical care medicine

    2019  Volume 199, Issue 4, Page(s) 397–399

    MeSH term(s) Anti-Asthmatic Agents/therapeutic use ; Asthma/drug therapy ; Asthma/etiology ; Asthma/genetics ; Biomedical Research ; Humans
    Chemical Substances Anti-Asthmatic Agents
    Language English
    Publishing date 2019-02-15
    Publishing country United States
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.201901-0013ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  5. Article: CO and O

    García-Martínez, Fernando / Turco, Elia / Schiller, Frederik / Ortega, J Enrique

    ACS catalysis

    2024  Volume 14, Issue 8, Page(s) 6319–6327

    Abstract: We investigate the chemical interaction of carbon monoxide (CO) and oxygen ( ... ...

    Abstract We investigate the chemical interaction of carbon monoxide (CO) and oxygen (O
    Language English
    Publishing date 2024-04-10
    Publishing country United States
    Document type Journal Article
    ISSN 2155-5435
    ISSN 2155-5435
    DOI 10.1021/acscatal.4c00435
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Blood transfusion and surgical treatment increase mortality in patient with proximal humeral fractures.

    Fernández-Cortiñas, Ana Belén / Seoane-Pillado, Teresa / Marco Martínez, Fernando

    Injury

    2024  Volume 54 Suppl 7, Page(s) 111091

    Abstract: Introduction: Proximal humeral fractures (PHFs) often occur in elderly patients with osteoporosis and associated comorbidities. These patients constitute a special risk group. This study aimed to identify associations between comorbidities, treatment ... ...

    Abstract Introduction: Proximal humeral fractures (PHFs) often occur in elderly patients with osteoporosis and associated comorbidities. These patients constitute a special risk group. This study aimed to identify associations between comorbidities, treatment type, and mortality risk.
    Patients and methods: We conducted a retrospective chart review of a cohort of 350 patients with a diagnosis of PHF and a mean follow-up of 4.5 years. We analysed the 19 prefracture comorbidities included in the Charlson Comorbidity Index (CCI), haemoglobin (Hb) levels, blood transfusion needs, and treatment administered (surgery versus conservative). The nonparametric Kaplan-Meier method and Cox proportional hazards model were used to estimate the mortality risk.
    Results: Over a 4.5-year average follow-up of 350 patients, primarily elderly females, with proximal humerus fractures, several factors were associated with increased mortality. The Charlson Comorbidity Index (CCI) was a significant predictor, with patients having a CCI > 5 facing higher mortality risks, especially if they underwent surgery. Additionally, osteosynthesis was linked to a lower mortality rate compared to arthroplasty. Age, dementia, medical complications, and postfracture Hb level also influenced mortality rates. CONCLUSIóN: These findings emphasize the importance of considering comorbidities, specifically the Charlson Comorbidity Index (CCI), in determining patient outcomes, especially amongst elderly patients with proximal humerus fractures. Factors like age, dementia, and postfracture Hb level also play a crucial role in influencing mortality rates.
    Trial registration: The study received written approval from the regional Ethics Committee for Clinical Research (code 2016/125).
    MeSH term(s) Female ; Humans ; Aged ; Retrospective Studies ; Comorbidity ; Shoulder Fractures/surgery ; Shoulder Fractures/epidemiology ; Blood Transfusion ; Humeral Fractures ; Dementia
    Language English
    Publishing date 2024-01-13
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 218778-4
    ISSN 1879-0267 ; 0020-1383
    ISSN (online) 1879-0267
    ISSN 0020-1383
    DOI 10.1016/j.injury.2023.111091
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  7. Article ; Online: Childhood Asthma Inception and Progression: Role of Microbial Exposures, Susceptibility to Viruses and Early Allergic Sensitization.

    Martinez, Fernando D

    Immunology and allergy clinics of North America

    2019  Volume 39, Issue 2, Page(s) 141–150

    Abstract: Inappropriate responses to respiratory viruses, especially rhinovirus, and early allergic sensitization are the strongest contributors to the inception and persistence of early onset asthma. The ORMDL3 asthma locus in chromosome 17q seems to exert its ... ...

    Abstract Inappropriate responses to respiratory viruses, especially rhinovirus, and early allergic sensitization are the strongest contributors to the inception and persistence of early onset asthma. The ORMDL3 asthma locus in chromosome 17q seems to exert its effects by increasing susceptibility to human rhinovirus in early life. Being raised on animal farms is highly protective against the development of asthma, and this protective effect is mediated by exposure to microbes. Two trials in high-risk young children, one to prevent wheezing lower respiratory tract illness using bacterial lyophilizates and another using anti-immunoglobulin E to prevent asthma progression, are already under way.
    MeSH term(s) Allergens/immunology ; Asthma/epidemiology ; Asthma/prevention & control ; Child ; Disease Progression ; Disease Susceptibility ; Environmental Exposure/adverse effects ; Host-Pathogen Interactions ; Humans ; Immunization ; Microbiota/immunology ; United States/epidemiology ; Virus Diseases/epidemiology
    Chemical Substances Allergens
    Language English
    Publishing date 2019-04-06
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 92606-1
    ISSN 1557-8607 ; 0889-8561
    ISSN (online) 1557-8607
    ISSN 0889-8561
    DOI 10.1016/j.iac.2018.12.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Potential uses of cytisine for smoking cessation in menopausal women - literature summary.

    Rubio, Francisco Rubio / Martínez, Fernando Martínez / Romero, Maria José Zarzuelo

    Przeglad menopauzalny = Menopause review

    2023  Volume 22, Issue 1, Page(s) 42–48

    Abstract: Introduction: Menopause is a vital stage in which the risk of the appearance of metabolic syndrome and cardiovascular diseases is increased. Cardiovascular risk in menopausal women must be monitored because it is one of the most common causes of ... ...

    Abstract Introduction: Menopause is a vital stage in which the risk of the appearance of metabolic syndrome and cardiovascular diseases is increased. Cardiovascular risk in menopausal women must be monitored because it is one of the most common causes of mortality in these women. Smoking is an important risk factor for the development of many diseases, including cardiovascular diseases, so promoting smoking cessation in these women is important for the maintenance of cardiovascular health.
    Material and methods: Current smoking cessation programs mainly include nicotine and varenicline as therapeutic agents, due to their history of success, safety, and efficacy in aiding in cessation, but they do not include "new" agents such as cytisine as coadjuvant in the elimination of the habit of smoking.
    Results: Cytisine is a therapeutic agent traditionally used in Eastern Europe, which has demonstrated efficacy and safety in smoking cessation, also showing other new pharmacological actions. It has been widely used since World War II as a nicotine substitute.
    Conclusions: These pharmacological actions, together with their efficacy in smoking cessation, should be explored to evaluate the convenience of the use of cytisine in premenopausal and postmenopausal women, so that cytisine can be identified as a useful therapeutic tool in smoking cessation programs and in particular in menopausal women.
    Language English
    Publishing date 2023-04-03
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2596140-8
    ISSN 2299-0038 ; 1643-8876
    ISSN (online) 2299-0038
    ISSN 1643-8876
    DOI 10.5114/pm.2023.126439
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Una aproximación al coste presupuestario de universalizar la salud bucodental en España.

    Montero-Soler, Alberto / Sánchez-Martínez, Fernando Ignacio

    Gaceta sanitaria

    2023  Volume 37, Page(s) 102285

    Abstract: Objective: To make an approximation to an estimate of the impact that an increase in the portfolio of oral health benefits would have on public health spending, which would at least cover most of the therapeutic treatments that households currently pay ... ...

    Title translation Approximation to the budgetary cost of universalizing oral health in Spain.
    Abstract Objective: To make an approximation to an estimate of the impact that an increase in the portfolio of oral health benefits would have on public health spending, which would at least cover most of the therapeutic treatments that households currently pay for privately.
    Method: This estimate is based on the level of expenditure on dental services of the Health Accounts System for the year 2020. The data of increased demand is extracted from a RAND's study on universalization of services. Then we carry out various linear projections of increased spending by introducing several linear co-payment assumptions to explore the impact of different mixed financing mechanisms.
    Results: The increase in the demand for treatment would be 47.54% with respect to the current level of spending and that, under the starting assumptions, the increase in public spending would reach some 5345 million euros. Various co-pay scenarios could reduce budget impact.
    Conclusions: Despite the improvement in the oral health of the Spanish population, there are still problems derived from the existence of a socioeconomic gradient that promotes the concentration of the presence and prevalence of diseases in the lowest socioeconomic levels. Extending the services of the oral-dental portfolio to attend to the entire population would increase public health spending by 0.48 points over GDP and, even so, Spanish public health spending would continue to be below the EU-27 average.
    MeSH term(s) Humans ; Spain ; Oral Health ; Health Expenditures ; Family Characteristics
    Language Spanish
    Publishing date 2023-01-04
    Publishing country Spain
    Document type English Abstract ; Journal Article
    ZDB-ID 1038713-4
    ISSN 1578-1283 ; 0213-9111
    ISSN (online) 1578-1283
    ISSN 0213-9111
    DOI 10.1016/j.gaceta.2022.102285
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Phoenix from the Ashes: Celebrating the 2023 North American Cystic Fibrosis Conference.

    Bush, Andrew / Ramsey, Bonnie / Shteinberg, Michal / Martinez, Fernando

    American journal of respiratory and critical care medicine

    2023  Volume 208, Issue 9, Page(s) 909–910

    MeSH term(s) Humans ; Cystic Fibrosis/drug therapy ; Cystic Fibrosis/genetics ; North America
    Language English
    Publishing date 2023-10-11
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202309-1603ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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