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  1. Article ; Online: Hipertensión arterial por hiperactividad simpática tras traumatismo craneoencefálico grave.

    Vázquez Sánchez, T / Gámez España, J P / Martínez Esteban, M D

    Hipertension y riesgo vascular

    2020  Volume 38, Issue 1, Page(s) 44–47

    Abstract: We present the case of a 34-year-old patient with severe head trauma and severe brain involvement. The patient deteriorated progressively and required several reinterventions for bleeding and brain herniation. We were consulted by neurosurgery due to ... ...

    Title translation HYpertension due to sympathetic hyperactivity after severe head injury.
    Abstract We present the case of a 34-year-old patient with severe head trauma and severe brain involvement. The patient deteriorated progressively and required several reinterventions for bleeding and brain herniation. We were consulted by neurosurgery due to irregular blood pressure control despite treatment with calcium antagonists. The patient had associated diaphoresis, tachypnoea and tachycardia, together with persistent high-grade fever with no microbiological evidence. Laboratory tests showed normal kidney function, with no proteinuria and no signs of left ventricular hypertrophy to suggest previous arterial hypertension. This led us to consider sympathetic hyperactivity syndrome as a first possible diagnosis due to severe neurological damage. In line with this suspicion, antihypertensive therapy was initiated which included non-cardioselective beta-blockers, alpha-2 agonists, benzodiazepines and GABA receptor agonists. Thus, we were able to improve the labile blood pressure levels, which supports the diagnosis.
    MeSH term(s) Adult ; Antihypertensive Agents/administration & dosage ; Autonomic Nervous System Diseases/complications ; Autonomic Nervous System Diseases/diagnosis ; Autonomic Nervous System Diseases/etiology ; Blood Pressure/drug effects ; Craniocerebral Trauma/complications ; Humans ; Hypertension/drug therapy ; Hypertension/etiology ; Male ; Syndrome
    Chemical Substances Antihypertensive Agents
    Language Spanish
    Publishing date 2020-06-27
    Publishing country Spain
    Document type Case Reports
    ISSN 1989-4805
    ISSN (online) 1989-4805
    DOI 10.1016/j.hipert.2020.06.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Neuropatía óptica isquémica no arterítica como lesión de órgano diana en la hipertensión arterial.

    Pozo-Álvarez, R / Vázquez-Sánchez, T / Martínez-Esteban, M D

    Hipertension y riesgo vascular

    2020  Volume 38, Issue 2, Page(s) 99–101

    Abstract: A 39-year-old black male who consulted with sudden and painless loss of vision in his right eye in the context of a hypertensive crisis. A history of essential arterial hypertension uncontrolled at home due to lack of therapeutic adherence and with ... ...

    Title translation Non-arteritic ischaemic optic neuropathy as a target organ lesion in arterial hypertension.
    Abstract A 39-year-old black male who consulted with sudden and painless loss of vision in his right eye in the context of a hypertensive crisis. A history of essential arterial hypertension uncontrolled at home due to lack of therapeutic adherence and with target organ involvement: lacunar infarct, grade IV hypertensive retinopathy and left ventricular concentric hypertrophy. Renal function was normal, without albuminuria. The clinical picture was classified as non-arteritic ischaemic optic neuropathy after ruling out vascular, traumatic, infectious and autoimmune disease. The patient presented discrete improvement of the visual deficit with the control of blood pressure. From his history and complementary tests, it was concluded that the ischaemic optic neuropathy was due to malignization of his arterial hypertension.
    MeSH term(s) Adult ; Humans ; Hypertension/complications ; Male ; Optic Neuropathy, Ischemic/etiology
    Language Spanish
    Publishing date 2020-10-06
    Publishing country Spain
    Document type Case Reports
    ISSN 1989-4805
    ISSN (online) 1989-4805
    DOI 10.1016/j.hipert.2020.08.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Mortality and cardiovascular risk in vasculitis ANCA. Importance of hypertension and renal function. Experience from southern Spain.

    Martin-Gómez, M A / Rodríguez Torres, A / Espinosa Hernández, M / Lopez Mendoza, M / Sabio Sánchez, J M / Martin Armada, M / Martin Suarez, I / Callejas Rubio, J L / Castilla Castellano, M M / Anglada Pintado, J C / Barnosi Marín, A C / Martinez Esteban, M D / Castilla Guerra, L / De Ramón Garrido, E

    Hipertension y riesgo vascular

    2023  Volume 41, Issue 1, Page(s) 5–16

    Abstract: Background: Cardiovascular disease (CVD) is one of the principal causes of death in antineutrophil cytoplasmic antibody-(ANCA)-associated vasculitis (AAV).: Objectives: To evaluate the mortality and it's causes and CVD and its vascular risk factors ( ... ...

    Abstract Background: Cardiovascular disease (CVD) is one of the principal causes of death in antineutrophil cytoplasmic antibody-(ANCA)-associated vasculitis (AAV).
    Objectives: To evaluate the mortality and it's causes and CVD and its vascular risk factors (VRFs) in AAV patients in Andalusia.
    Methods: A multicenter cohort of 220 AAV patients followed-up from 1979 until June 2020 was studied in Andalussia, south of Spain. The information, including socio-demographic and clinical data was recorded retrospectively through chart review. Data was analysed using Chi
    Results: During a mean ± standard deviation follow-up of 96.79 ± 75.83 months, 51 patients died and 30 presented at least one CVE. Independent prognostic factors of mortality were age (HR 1.083, p=0.001) and baseline creatinine (HR 4.41, p=0.01). Independent prognostic factors of CVE were age [hazard ratio (HR) 1.042, p=0.005] and the presence of hypertension (HTN) six months after diagnosis (HR 4.641, p=0.01). HTN, diabetes and renal failure, all of these important VRFs, are more prevalent in AAV patients than it is described in matched general population.
    Conclusions: Age and baseline renal function, but not CVEs, are predictors of mortality and age and early HTN are independent predictors for having a CVE. CVD screening in AAV patients is demanded.
    MeSH term(s) Humans ; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/complications ; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/diagnosis ; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/epidemiology ; Antibodies, Antineutrophil Cytoplasmic ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/etiology ; Heart Disease Risk Factors ; Hypertension/complications ; Hypertension/epidemiology ; Kidney ; Retrospective Studies ; Risk Factors ; Spain/epidemiology
    Chemical Substances Antibodies, Antineutrophil Cytoplasmic
    Language English
    Publishing date 2023-07-28
    Publishing country Spain
    Document type Multicenter Study ; Journal Article
    ISSN 1989-4805
    ISSN (online) 1989-4805
    DOI 10.1016/j.hipert.2023.06.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Derrame pleuropericárdico como debut de una granulomatosis de Wegener.

    Martínez Esteban, M D / Palomares, M / Martínez Benavides, E / Asensio, C

    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia

    2006  Volume 26, Issue 1, Page(s) 139–140

    Title translation Pleuro-pericardial effusion as the initial manifestation of Wegener's granulomatosis.
    MeSH term(s) Glomerulosclerosis, Focal Segmental/etiology ; Granulomatosis with Polyangiitis/complications ; Granulomatosis with Polyangiitis/diagnosis ; Granulomatosis with Polyangiitis/epidemiology ; Humans ; Incidence ; Male ; Middle Aged ; Pericardial Effusion/etiology ; Pleural Effusion/etiology ; Smoking
    Language Spanish
    Publishing date 2006
    Publishing country Spain
    Document type Case Reports ; Letter
    ZDB-ID 632512-9
    ISSN 1989-2284 ; 0211-6995
    ISSN (online) 1989-2284
    ISSN 0211-6995
    Database MEDical Literature Analysis and Retrieval System OnLINE

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