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  1. Book ; Online: Green Nanotechnology

    Martins, Roberto / Kaczerewska, Olga Barbara

    The Latest Innovations, Knowledge Gaps, and Future Perspectives

    2022  

    Keywords Technology: general issues ; carvacrol ; stearic acid ; beeswax ; carnauba wax ; nanostructured lipid carriers ; crystallinity ; cationic surfactants ; microemulsion ; mesoporous silica ; encapsulation ; ecotoxicity ; Perna perna ; biofouling ; nanotechnology ; toxicity ; silver nanoparticles ; gemini surfactant ; green synthesis ; black nickel coatings ; electrochemical testing ; electrodeposition ; hull cell ; nanostructured coatings ; green nanotechnology ; green chemistry ; safe-by-design ; sustainability ; nanomaterials ; nanoparticles ; nanoecotoxicology ; environmental risk assessment
    Language 0|e
    Size 1 electronic resource (84 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021611192
    ISBN 9783036520087 ; 3036520082
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Human‐mediated introduction of introgressed deer across Wallace's line: Historical biogeography of Rusa unicolor and R. timorensis

    Martins, Renata / Meneghini, Dorina

    Ecology and evolution, 8(3):1465-1479

    2017  

    Abstract: In this study we compared the phylogeographic patterns of two Rusa species, Rusa unicolor and Rusa timorensis, in order to understand what drove and maintained differentiation between these two geographically and genetically close species and ... ...

    Institution Leibniz-Institut für Zoo- und Wildtierforschung (Berlin)
    Abstract In this study we compared the phylogeographic patterns of two Rusa species, Rusa unicolor and Rusa timorensis, in order to understand what drove and maintained differentiation between these two geographically and genetically close species and investigated the route of introduction of individuals to the islands outside of the Sunda Shelf. We analyzed full mitogenomes from 56 archival samples from the distribution areas of the two species and 18 microsatellite loci in a subset of 16 individuals to generate the phylogeographic patterns of both species. Bayesian inference with fossil calibration was used to estimate the age of each species and major divergence events. Our results indicated that the split between the two species took place during the Pleistocene, ~1.8 Mya, possibly driven by adaptations of R. timorensis to the drier climate found on Java compared to the other islands of Sundaland. Although both markers identified two well‐differentiated clades, there was a largely discrepant pattern between mitochondrial and nuclear markers. While nDNA separated the individuals into the two species, largely in agreement with their museum label, mtDNA revealed that all R. timorensis sampled to the east of the Sunda shelf carried haplotypes from R. unicolor and one Rusa unicolor from South Sumatra carried a R. timorensis haplotype. Our results show that hybridization occurred between these two sister species in Sundaland during the Late Pleistocene and resulted in human‐mediated introduction of hybrid descendants in all islands outside Sundaland.
    Keywords Cervidae ; Sundaland ; Phylogeography ; Wallace's line ; human introduction ; hybridization
    Language English
    Document type Article
    Database Repository for Life Sciences

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  3. Article: Population and landscape genetic analysis of the Malayan sun bear Helarctos malayanus

    Kunde, Miriam / Martins, Renata / Förster, Daniel

    Conservation genetics, 21:123-135

    2019  

    Abstract: Conservation genetics can provide data needed by conservation practitioners for their decisions regarding the management of vulnerable or endangered species, such as the sun bear Helarctos malayanus. Throughout its range, the sun bear is threatened by ... ...

    Institution Leibniz-Institut für Zoo- und Wildtierforschung (Berlin)
    Abstract Conservation genetics can provide data needed by conservation practitioners for their decisions regarding the management of vulnerable or endangered species, such as the sun bear Helarctos malayanus. Throughout its range, the sun bear is threatened by loss and fragmentation of its habitat and the illegal trade of both live bears and bear parts. Sharply declining population numbers and population sizes, and a lack of natural dispersal between populations all threaten the genetic diversity of the remaining populations of this species. In this first population genetics study of sun bears using microsatellite markers, we analyzed 68 sun bear samples from Cambodia to investigate population structure and genetic diversity. We found evidence for two genetically distinct populations in the West and East of Cambodia. Ongoing or recent gene flow between these populations does not appear sufficient to alleviate loss of diversity in these populations, one of which (West Cambodia) is characterized by significant inbreeding. We were able to assign 85% of sun bears of unknown origin to one of the two populations with high confidence (assignment probability ≥ 85%), providing valuable information for future bear reintroduction programs. Further, our results suggest that developed land (mostly agricultural mosaics) acts as a barrier to gene flow for sun bears in Cambodia. We highlight that regional sun bear conservation action plans should consider promoting population connectivity and enforcing wildlife protection of this threatened species.
    Keywords Helarctos malayanus ; Microsatellite ; Sun bear ; Population genetics
    Language English
    Document type Article
    Database Repository for Life Sciences

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  4. Article ; Online: The effect of a home-based, gamified stability skills intervention on 4-5-year-old children's physical and cognitive outcomes: A pilot study.

    Fitton Davies, K / Clarke, S / Martins, R / Rudd, J R / Duncan, M

    Psychology of sport and exercise

    2024  Volume 73, Page(s) 102636

    Abstract: Background: Stability skills (e.g., static/dynamic balance) are a precursor for other movement skill development (e.g., jumping, catching). However, young children consistently demonstrate low stability and movement skill ability. There is therefore a ... ...

    Abstract Background: Stability skills (e.g., static/dynamic balance) are a precursor for other movement skill development (e.g., jumping, catching). However, young children consistently demonstrate low stability and movement skill ability. There is therefore a need to develop effective strategies to improve stability skills in early childhood.
    Aim: To pilot the effect of a home-based gamified stability skills intervention on 4-5-year-old children's physical skills, self-perceptions and cognitions.
    Methods: One-hundred-and-eleven 4-5-year-old children participated from three schools. Two schools were allocated into the intervention group (n = 66 children, 33 boys) and one to the control group (n = 45 children, 25 boys). Stability, fundamental movement skills, perceived motor competence, and cognition were assessed at baseline and at post-intervention. The intervention group was given a booklet detailing the 12-week gamified stability skill intervention. The control group participated in their usual weekly activities.
    Results: A series of ANCOVAs controlling for baseline values demonstrated significantly higher stability skills (F(1,93) = 24.79, p < 0.001, partial η
    Discussion: This study demonstrates that a home-based, gamified, stability skills intervention enhances stability skills, fundamental movement skills, perceived motor competence and cognition in children aged 4-5-years old.
    Language English
    Publishing date 2024-04-06
    Publishing country Netherlands
    Document type Journal Article
    ISSN 1878-5476
    ISSN (online) 1878-5476
    DOI 10.1016/j.psychsport.2024.102636
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The effects of low-volume combined training on health-related physical fitness outcomes in active young adults: A controlled clinical trial.

    Martins, Ricardo / Loureiro, Nuno

    Sports medicine and health science

    2023  Volume 5, Issue 1, Page(s) 74–80

    Abstract: The effects of combined training (CT) on improving general health are well known, however, few studies have investigated the effects of low-volume CT. So, the aim of this study is to investigate the effects of 6 weeks of low-volume CT on body composition, ...

    Abstract The effects of combined training (CT) on improving general health are well known, however, few studies have investigated the effects of low-volume CT. So, the aim of this study is to investigate the effects of 6 weeks of low-volume CT on body composition, handgrip strength (HGS), cardiorespiratory fitness (CRF) and affective response (AR) to exercise. Eighteen healthy, active young adult man (mean ​± ​
    Language English
    Publishing date 2023-01-02
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2666-3376
    ISSN (online) 2666-3376
    DOI 10.1016/j.smhs.2022.12.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Algae-Based Supplements Claiming Weight Loss Properties: Authenticity Control and Scientific-Based Evidence on Their Effectiveness.

    Fernandes, Fátima / Martins, Raquel / Barbosa, Mariana / Valentão, Patrícia

    Marine drugs

    2024  Volume 22, Issue 3

    Abstract: The worldwide prevalence of obesity impacts more than 600 million adults. Successfully managing weight is effective in reducing the risk of chronic diseases, but sustaining long-term weight loss remains a challenge. Although there are supplements based ... ...

    Abstract The worldwide prevalence of obesity impacts more than 600 million adults. Successfully managing weight is effective in reducing the risk of chronic diseases, but sustaining long-term weight loss remains a challenge. Although there are supplements based on algae that claim to aid in weight loss, there is a notable scarcity of scientific evidence supporting their effectiveness, and their regular consumption safety remains inadequately addressed. In this work, commercially available
    MeSH term(s) Animals ; Decapodiformes ; Dietary Supplements ; Nitric Oxide ; Plant Extracts ; Spirulina
    Chemical Substances Nitric Oxide (31C4KY9ESH) ; Plant Extracts
    Language English
    Publishing date 2024-03-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175190-0
    ISSN 1660-3397 ; 1660-3397
    ISSN (online) 1660-3397
    ISSN 1660-3397
    DOI 10.3390/md22030123
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Hemorrhagic Presentation in Primary Central Nervous System Lymphoma: A Case Study.

    Rodrigues, Filipa Marques / Santos, Mariana / Martins, Ricardo

    The American journal of case reports

    2024  Volume 25, Page(s) e942951

    Abstract: BACKGROUND Primary central nervous system diffuse large B-cell lymphoma (DLBCL) is an extremely aggressive brain disease that rarely affects immunocompetent non-elderly patients, particularly with hemorrhagic presentation. Brain magnetic resonance ... ...

    Abstract BACKGROUND Primary central nervous system diffuse large B-cell lymphoma (DLBCL) is an extremely aggressive brain disease that rarely affects immunocompetent non-elderly patients, particularly with hemorrhagic presentation. Brain magnetic resonance imaging (MRI) plays an important role in the diagnosis of this entity, which typically demonstrates restricted diffusion and a T2 hypointense appearance, suggesting hypercellularity. CASE REPORT A 44-year-old man came to the emergency department with a persistent and treatment-resistant bilateral frontal headache that had been bothering him for the past 3 weeks. Upon conducting a neurological assessment, the patient displayed temporal disorientation and incoherent speech, but without any observable motor deficits. A non-contrast enhanced brain computed tomography scan was carried out, revealing a hyperattenuating, space-occupying lesion and hemorrhage in the left hemisphere of the brain. Subsequently, brain MRI demonstrated hypointense signal on T2-weighted images, restricted diffusion, and homogeneous lesional contrast enhancement, suggesting a very cellular expansive lesion with hemorrhage. To establish a definitive diagnosis, a brain biopsy was undertaken, confirming the presence of DLBCL of the primary central nervous system (germinal center phenotype). CONCLUSIONS Hemorrhagic presentation of primary central nervous system DLBCL occurs very rarely, particularly in non-elderly immunocompetent patients. Brain MRI plays an important role in the diagnosis of this entity, which allows differentiation from high-grade glial or other lesions that present more frequently with hemorrhage. Therefore, it is crucial to suspect lymphoma before surgical intervention for appropriate patient management.
    MeSH term(s) Adult ; Humans ; Male ; Brain/pathology ; Central Nervous System Neoplasms/complications ; Central Nervous System Neoplasms/diagnostic imaging ; Hemorrhage ; Lymphoma, Large B-Cell, Diffuse/complications ; Lymphoma, Large B-Cell, Diffuse/diagnostic imaging ; Lymphoma, Large B-Cell, Diffuse/pathology ; Magnetic Resonance Imaging/methods
    Language English
    Publishing date 2024-04-02
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2517183-5
    ISSN 1941-5923 ; 1941-5923
    ISSN (online) 1941-5923
    ISSN 1941-5923
    DOI 10.12659/AJCR.942951
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Pharmacologic Anisocoria With Azelastine: The Importance of a Good Anamnesis.

    Ribeiro, Margarida / Teixeira-Martins, Rita / Meira, Jorge

    Cureus

    2024  Volume 16, Issue 3, Page(s) e56649

    Abstract: Unilateral pharmacologic mydriasis is one of the differential diagnoses of anisocoria. This is a clinical case of a 37-year-old male patient admitted to the ophthalmology emergency department with unilateral mydriasis, an infrequent side effect of the ... ...

    Abstract Unilateral pharmacologic mydriasis is one of the differential diagnoses of anisocoria. This is a clinical case of a 37-year-old male patient admitted to the ophthalmology emergency department with unilateral mydriasis, an infrequent side effect of the antihistaminic drug azelastine. A comprehensive medical history including ocular medication was essential to avoid the need for additional tests and to exclude life-threatening conditions responsible for a similar presentation.
    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.56649
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Valuing live births from assisted reproduction: A health economics viewpoint.

    Martins, Rui / Connolly, Mark P

    Best practice & research. Clinical obstetrics & gynaecology

    2022  Volume 85, Issue Pt B, Page(s) 149–158

    Abstract: Infertility is a medical condition that can be overcome, thanks to advances in medically assisted reproductive (MAR) therapies. Despite the ultimate measure of MAR efficacy being the birth of a new human being, there are ethical and methodological ... ...

    Abstract Infertility is a medical condition that can be overcome, thanks to advances in medically assisted reproductive (MAR) therapies. Despite the ultimate measure of MAR efficacy being the birth of a new human being, there are ethical and methodological questions as to which outcome best translates the value of MAR in cost-effectiveness analyses. Many authors favour cost per life birth outcomes instead of more traditional cost per quality-adjusted life years (QALYs), which raises generalizability issues for decision-makers. Nonetheless, infertility and infertility treatments substantially differ from other health conditions and health treatments, particularly in the way they affect the quality of life of the infertile couple. Collecting quality of life measures in infertility and pregnancy is also surrounded by challenges not easily overcome. We reflect on cost-effectiveness methods applied to MAR technologies, on ethical considerations for valuing a MAR-generated life, and on its broader societal value for consideration by decision-makers.
    Language English
    Publishing date 2022-10-22
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2050090-7
    ISSN 1532-1932 ; 1521-6934
    ISSN (online) 1532-1932
    ISSN 1521-6934
    DOI 10.1016/j.bpobgyn.2022.10.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Major Cost Drivers in Assessing the Economic Burden of Alzheimer's Disease: A Structured, Rapid Review.

    Kosaner Kließ, M / Martins, R / Connolly, M P

    The journal of prevention of Alzheimer's disease

    2021  Volume 8, Issue 3, Page(s) 362–370

    Abstract: Background: Alzheimer's Disease is the most common cause of dementia, affecting memory, thinking and behavior. Symptoms eventually grow severe enough to interfere with daily tasks. AD is predicted to increase healthcare spending and costs associated ... ...

    Abstract Background: Alzheimer's Disease is the most common cause of dementia, affecting memory, thinking and behavior. Symptoms eventually grow severe enough to interfere with daily tasks. AD is predicted to increase healthcare spending and costs associated with formal and informal caregiving. The aim of this study was to identify and quantify the contribution of the different cost components associated with AD.
    Methods: A structured literature review was conducted to identify studies reporting the economic burden of Alzheimer`s Disease beyond the healthcare setting. The search was conducted in Medline, Embase and EconLit and limited to studies published in the last 10 years. For each identified cost component, frequency weighted mean costs were calculated across countries to estimate the percentage contribution of each component by care setting and disease severity. Results obtained by each costing approach were also compared.
    Results: For community-dwelling adults, the percentage of healthcare, social care and indirect costs to total costs were 13.9%, 17.4% and 68.7%, respectively. The percentage of costs varied by disease severity with 26.0% and 10.4% of costs spent on healthcare for mild and severe disease, respectively. The proportion of total spending on indirect costs changed from 60.7% to 72.5% as disease progressed. For those in residential care, the contribution of each cost component was similar between moderate and severe disease. Social care accounted on average for 85.9% of total costs.
    Conclusion: The contribution of healthcare costs to the overall burden was not negligible; but was generally exceeded by social and informal care costs.
    MeSH term(s) Alzheimer Disease/economics ; Caregivers/economics ; Cost of Illness ; Health Care Costs ; Humans ; Independent Living/economics ; Residential Facilities/economics ; Severity of Illness Index
    Language English
    Publishing date 2021-10-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2782183-3
    ISSN 2426-0266 ; 2274-5807
    ISSN (online) 2426-0266
    ISSN 2274-5807
    DOI 10.14283/jpad.2021.17
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