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  1. Article ; Online: Analysis of Cardiovascular Hemodynamic and Autonomic Variables in Individuals with Systemic Arterial Hypertension, Type 2 Diabetes Mellitus, and Parkinson's Disease: A Comparative Study.

    Yuphiwa Ngomane, Awassi / Martins de Abreu, Raphael / Fernandes, Bianca / Roque Marçal, Isabela / Veiga Guimarães, Guilherme / Gomes Ciolac, Emmanuel

    Clinical and experimental hypertension (New York, N.Y. : 1993)

    2021  Volume 44, Issue 2, Page(s) 119–126

    Abstract: Background: Systemic arterial hypertension (SAH), type 2 diabetes mellitus (T2DM), and Parkinson's disease (PD) are highly prevalent chronic diseases that can significantly impact the cardiovascular system.: Aim: The aim of this study was to compare ... ...

    Abstract Background: Systemic arterial hypertension (SAH), type 2 diabetes mellitus (T2DM), and Parkinson's disease (PD) are highly prevalent chronic diseases that can significantly impact the cardiovascular system.
    Aim: The aim of this study was to compare hemodynamic and autonomic variables at rest in individuals with SAH, T2DM, or PD.
    Methods: Fifty sedentary or insufficiently active individuals (22 men) with SAH (age = 66 ± 5.0 yr), T2DM (age = 52 ± 10 yr) or PD (age = 68 ± 8.0 yr) had their resting blood pressure (BP), arterial stiffness, endothelial function, and heart rate variability (HRV) assessed and compared.
    Results: Systolic and diastolic BP were higher in SAH (130 ± 10 / 80 ± 10 mmHg) than T2DM (110 ± 14 / 75 ± 11 mmHg) and PD, and (123 ± 20 / 70 ± 11 mmHg) respectively. T2DM individuals showed lower arterial stiffness (8.4 ± 1.1 m/s), when compared to SAH (10.3 ± 2.3 m/s) and PD (10.6 ± 3.0 m/s). T2DM had greater resting tachycardia showed by the mean RR (759 ± 79 ms), than SAH (962 ± 169 ms) and PD (976 ± 134 ms), which was accompanied by higher sympathetic modulation (low frequency [LF]: 62 ± 19 nu) and lower parasympathetic modulation (high frequency [HF]: 32 ± 16 nu) when compared to SAH (LF: 40 ± 16 nu; HF: 61 ± 33 nu). No differences among groups were found on non-linear HRV markers and endothelial reactivity indexes.
    Conclusions: Individuals with T2DM showed impaired levels of cardiac autonomic markers when compared to individuals with SAH and PD, despite of having lower levels of BP and arterial stiffness.
    MeSH term(s) Adult ; Aged ; Blood Pressure ; Diabetes Mellitus, Type 2/complications ; Heart ; Heart Rate ; Hemodynamics ; Humans ; Hypertension ; Male ; Middle Aged ; Parkinson Disease
    Language English
    Publishing date 2021-12-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 604757-9
    ISSN 1525-6006 ; 0730-0077
    ISSN (online) 1525-6006
    ISSN 0730-0077
    DOI 10.1080/10641963.2021.2001480
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Acute high-intensity interval exercise versus moderate-intensity continuous exercise in heated water-based on hemodynamic, cardiac autonomic, and vascular responses in older individuals with hypertension.

    Roque Marçal, Isabela / Teixeira Do Amaral, Vanessa / Fernandes, Bianca / Martins de Abreu, Raphael / Alvarez, Cristian / Veiga Guimarães, Guilherme / Cornelissen, Véronique A / Gomes Ciolac, Emmanuel

    Clinical and experimental hypertension (New York, N.Y. : 1993)

    2022  Volume 44, Issue 5, Page(s) 427–435

    Abstract: Objectives: This crossover study design aimed to assess hemodynamic, cardiac autonomic, and vascular responses to high-intensity interval (HIIE) vs moderate-intensity continuous exercise (MICE) in older individuals with hypertension.: Methods: Twenty ...

    Abstract Objectives: This crossover study design aimed to assess hemodynamic, cardiac autonomic, and vascular responses to high-intensity interval (HIIE) vs moderate-intensity continuous exercise (MICE) in older individuals with hypertension.
    Methods: Twenty (67 ± 7 y) older individuals with hypertension were randomly assigned to perform HIIE, MICE, or control (CON) sessions in the heated swimming pool (30-32°C). Blood pressure (BP), arterial stiffness, endothelial reactivity, and heart rate variability (HRV) were measured pre, post, and 45 min (recovery) after each intervention followed by 24-h ambulatory BP and HRV.
    Results: One single aerobic exercise session was not effective to provoke post-exercise hypotension and vascular improvements. HIIE was superior to MICE and CON to increasing parasympathetic modulation at post and recovery. Exercise sessions showed to disturb the autonomic system at nighttime compared to CON.
    Conclusions: These results may have important implications in water-based therapy and the elderly with hypertension.
    MeSH term(s) Aged ; Aquatic Therapy/methods ; Autonomic Nervous System/physiopathology ; Blood Pressure/physiology ; Blood Vessels/physiopathology ; Cross-Over Studies ; Exercise/physiology ; Heart/innervation ; Heart/physiopathology ; Heart Rate/physiology ; Heating ; Hemodynamics/physiology ; High-Intensity Interval Training/methods ; Humans ; Hypertension/physiopathology ; Hypertension/therapy ; Middle Aged
    Language English
    Publishing date 2022-04-19
    Publishing country England
    Document type Comparative Study ; Journal Article ; Randomized Controlled Trial
    ZDB-ID 604757-9
    ISSN 1525-6006 ; 0730-0077
    ISSN (online) 1525-6006
    ISSN 0730-0077
    DOI 10.1080/10641963.2022.2065288
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Cardiac baroreflex hysteresis is one of the determinants of the heart period variability asymmetry.

    De Maria, Beatrice / Bari, Vlasta / Cairo, Beatrice / Vaini, Emanuele / Martins de Abreu, Raphael / Perseguini, Natalia Maria / Milan-Mattos, Juliana / Rehder-Santos, Patricia / Minatel, Vinícius / Catai, Aparecida Maria / Dalla Vecchia, Laura Adelaide / Porta, Alberto

    American journal of physiology. Regulatory, integrative and comparative physiology

    2019  Volume 317, Issue 4, Page(s) R539–R551

    Abstract: In heart period (HP) variability (HPV) recordings the percentage of negative HP variations tends to be greater than that of positive ones and this pattern is referred to as HPV asymmetry (HPVA). HPVA has been studied in several experimental conditions in ...

    Abstract In heart period (HP) variability (HPV) recordings the percentage of negative HP variations tends to be greater than that of positive ones and this pattern is referred to as HPV asymmetry (HPVA). HPVA has been studied in several experimental conditions in healthy and pathological populations, but its origin is unclear. The baroreflex (BR) exhibits an asymmetric behavior as well given that it reacts more importantly to positive than negative arterial pressure (AP) variations. We tested the hypothesis that the BR asymmetry (BRA) is a HPVA determinant over spontaneous fluctuations of HP and systolic AP (SAP). We studied 100 healthy subjects (age from 21 to 70 yr, 54 men) comprising 20 subjects in each age decade. Electrocardiogram and noninvasive AP were recorded for 15 min at rest in supine position (REST) and during active standing (STAND). The HPVA was evaluated via Porta's index and Guzik's index, while the BRA was assessed as the difference, and normalized difference, between BR sensitivities computed over positive and negative SAP variations via the sequence method applied to HP and SAP variability. HPVA significantly increased during STAND and decreased progressively with age. BRA was not significantly detected both at REST and during STAND. However, we found a significant positive association between BRA and HPVA markers during STAND persisting even within the age groups. This study supports the use of HPVA indexes as descriptors of BRA and identified a challenge soliciting the BR response like STAND to maximize the association between HPVA and BRA markers.
    MeSH term(s) Adult ; Aged ; Arterial Pressure/physiology ; Baroreflex ; Female ; Heart/physiology ; Heart Rate/physiology ; Humans ; Male ; Middle Aged ; Young Adult
    Language English
    Publishing date 2019-07-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603839-6
    ISSN 1522-1490 ; 0363-6119
    ISSN (online) 1522-1490
    ISSN 0363-6119
    DOI 10.1152/ajpregu.00112.2019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Effects of inspiratory muscle-training intensity on cardiovascular control in amateur cyclists.

    Martins de Abreu, Raphael / Porta, Alberto / Rehder-Santos, Patricia / Cairo, Beatrice / Donisete da Silva, Claudio / De Favari Signini, Étore / Sakaguchi, Camila Akemi / Catai, Aparecida Maria

    American journal of physiology. Regulatory, integrative and comparative physiology

    2019  Volume 317, Issue 6, Page(s) R891–R902

    Abstract: Chronic effects of inspiratory muscle training (IMT) on autonomic function and baroreflex regulation are poorly studied. This study aims at evaluating chronic effects of different IMT intensities on cardiovascular control in amateur cyclists. A ... ...

    Abstract Chronic effects of inspiratory muscle training (IMT) on autonomic function and baroreflex regulation are poorly studied. This study aims at evaluating chronic effects of different IMT intensities on cardiovascular control in amateur cyclists. A longitudinal, randomized, controlled blind study was performed on 30 recreational male cyclists undergoing IMT for 11 wk. Participants were randomly allocated into sham-trained group (SHAM,
    MeSH term(s) Athletes ; Baroreflex ; Bicycling ; Blood Pressure ; Breathing Exercises ; Humans ; Male ; Respiratory Physiological Phenomena
    Language English
    Publishing date 2019-10-09
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 603839-6
    ISSN 1522-1490 ; 0363-6119
    ISSN (online) 1522-1490
    ISSN 0363-6119
    DOI 10.1152/ajpregu.00167.2019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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