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  1. Artikel ; Online: Lassa Fever in Travelers from West Africa, 1969–2016

    Aaron Kofman / Mary J. Choi / Pierre E. Rollin

    Emerging Infectious Diseases, Vol 25, Iss 2, Pp 236-

    2019  Band 239

    Abstract: Lassa virus is a rodentborne arenavirus responsible for human cases of Lassa fever, a viral hemorrhagic fever, in West Africa and in travelers arriving to non–Lassa-endemic countries from West Africa. We describe a retrospective review performed through ... ...

    Abstract Lassa virus is a rodentborne arenavirus responsible for human cases of Lassa fever, a viral hemorrhagic fever, in West Africa and in travelers arriving to non–Lassa-endemic countries from West Africa. We describe a retrospective review performed through literature search of clinical and epidemiologic characteristics of all imported Lassa fever cases worldwide during 1969–2016. Our findings demonstrate that approximately half of imported cases had distinctive clinical features (defined as fever and >1 of the following: pharyngitis, sore throat, tonsillitis, conjunctivitis, oropharyngeal ulcers, or proteinuria). Delays in clinical suspicion of this diagnosis were common. In addition, no secondary transmission of Lassa fever to contacts of patients with low-risk exposures occurred, and infection of high-risk contacts was rare. Future public health investigations of such cases should focus on timely recognition of distinctive clinical features, earlier treatment of patients, and targeted public health responses focused on high-risk contacts.
    Schlagwörter Lassa fever ; travel medicine ; zoonotic diseases ; viruses ; West Africa ; zoonoses ; Medicine ; R ; Infectious and parasitic diseases ; RC109-216
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2019-02-01T00:00:00Z
    Verlag Centers for Disease Control and Prevention
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel ; Online: Detection of Hantavirus during the COVID-19 Pandemic, Arizona, USA, 2020

    Gavriella Hecht / Ariella P. Dale / Irene Ruberto / Guillermo Adame / Ryan Close / Sarah-Jean Snyder / Kathryn Pink / Nathanael Lemmon / Jessica Rudolfo / Michael Madsen / Andrea L. Wiens / Caitlin Cossaboom / Trevor Shoemaker / Mary J. Choi / Deborah Cannon / Inna Krapiunaya / Shannon Whitmer / Melissa Mobley / Emir Talundzic /
    John D. Klena / Heather Venkat

    Emerging Infectious Diseases, Vol 29, Iss 8, Pp 1663-

    2023  Band 1667

    Abstract: We identified 2 fatal cases of persons infected with hantavirus in Arizona, USA, 2020; 1 person was co-infected with SARS-CoV-2. Delayed identification of the cause of death led to a public health investigation that lasted ≈9 months after their deaths, ... ...

    Abstract We identified 2 fatal cases of persons infected with hantavirus in Arizona, USA, 2020; 1 person was co-infected with SARS-CoV-2. Delayed identification of the cause of death led to a public health investigation that lasted ≈9 months after their deaths, which complicated the identification of a vector or exposure.
    Schlagwörter hantavirus pulmonary syndrome ; viruses ; COVID-19 ; SARS-CoV-2 ; respiratory infections ; zoonoses ; Medicine ; R ; Infectious and parasitic diseases ; RC109-216
    Sprache Englisch
    Erscheinungsdatum 2023-08-01T00:00:00Z
    Verlag Centers for Disease Control and Prevention
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  3. Artikel ; Online: Development and implementation of the Ebola Exposure Window Calculator

    Amy Whitesell / Nirma D. Bustamante / Miles Stewart / Jeff Freeman / Amber M. Dismer / Walter Alarcon / Aaron Kofman / Amen Ben Hamida / Stuart T. Nichol / Inger Damon / Dana L. Haberling / Mory Keita / Gisèle Mbuyi / Gregory Armstrong / Derek Juang / Jason Dana / Mary J. Choi

    PLoS ONE, Vol 16, Iss

    A tool for Ebola virus disease outbreak field investigations

    2021  Band 8

    Abstract: During an Ebola virus disease (EVD) outbreak, calculating the exposure window of a confirmed case can assist field investigators in identifying the source of infection and establishing chains of transmission. However, field investigators often have ... ...

    Abstract During an Ebola virus disease (EVD) outbreak, calculating the exposure window of a confirmed case can assist field investigators in identifying the source of infection and establishing chains of transmission. However, field investigators often have difficulty calculating this window. We developed a bilingual (English/French), smartphone-based field application to assist field investigators in determining the exposure window of an EVD case. The calculator only requires the reported date of symptoms onset and the type of symptoms present at onset or the date of death. Prior to the release of this application, there was no similar electronic capability to enable consistent calculation of EVD exposure windows for field investigators. The Democratic Republic of the Congo Ministry of Health endorsed the application and incorporated it into trainings for field staff. Available for Apple and Android devices, the calculator continues to be downloaded even as the eastern DRC outbreak resolved. We rapidly developed and implemented a smartphone application to estimate the exposure window for EVD cases in an outbreak setting
    Schlagwörter Medicine ; R ; Science ; Q
    Thema/Rubrik (Code) 600
    Sprache Englisch
    Erscheinungsdatum 2021-01-01T00:00:00Z
    Verlag Public Library of Science (PLoS)
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: Development and implementation of the Ebola Exposure Window Calculator

    Amy Whitesell / Nirma D Bustamante / Miles Stewart / Jeff Freeman / Amber M Dismer / Walter Alarcon / Aaron Kofman / Amen Ben Hamida / Stuart T Nichol / Inger Damon / Dana L Haberling / Mory Keita / Gisèle Mbuyi / Gregory Armstrong / Derek Juang / Jason Dana / Mary J Choi

    PLoS ONE, Vol 16, Iss 8, p e

    A tool for Ebola virus disease outbreak field investigations.

    2021  Band 0255631

    Abstract: During an Ebola virus disease (EVD) outbreak, calculating the exposure window of a confirmed case can assist field investigators in identifying the source of infection and establishing chains of transmission. However, field investigators often have ... ...

    Abstract During an Ebola virus disease (EVD) outbreak, calculating the exposure window of a confirmed case can assist field investigators in identifying the source of infection and establishing chains of transmission. However, field investigators often have difficulty calculating this window. We developed a bilingual (English/French), smartphone-based field application to assist field investigators in determining the exposure window of an EVD case. The calculator only requires the reported date of symptoms onset and the type of symptoms present at onset or the date of death. Prior to the release of this application, there was no similar electronic capability to enable consistent calculation of EVD exposure windows for field investigators. The Democratic Republic of the Congo Ministry of Health endorsed the application and incorporated it into trainings for field staff. Available for Apple and Android devices, the calculator continues to be downloaded even as the eastern DRC outbreak resolved. We rapidly developed and implemented a smartphone application to estimate the exposure window for EVD cases in an outbreak setting.
    Schlagwörter Medicine ; R ; Science ; Q
    Thema/Rubrik (Code) 600
    Sprache Englisch
    Erscheinungsdatum 2021-01-01T00:00:00Z
    Verlag Public Library of Science (PLoS)
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  5. Artikel ; Online: Postmortem Surveillance for Ebola Virus Using OraQuick Ebola Rapid Diagnostic Tests, Eastern Democratic Republic of the Congo, 2019–2020

    Daniel Mukadi-Bamuleka / Yibayiri Osee Sanogo / Junior Bulabula-Penge / Maria E. Morales-Betoulle / Patrice Fillon / Patrick Woodruff / Mary J. Choi / Amy Whitesell / Alison M. Todres / Anja De Weggheleire / Anaïs Legand / Jean-Jacques Muyembe-Tamfum / Pierre Formenty / John D. Klena / Joel M. Montgomery / Steve Ahuka-Mundeke

    Emerging Infectious Diseases, Vol 28, Iss 2, Pp 420-

    2022  Band 424

    Abstract: After a pilot study, we tested 443 cadavers using OraQuick Ebola rapid diagnostic tests during surveillance after the 10th Ebola outbreak in the Democratic Republic of the Congo. No false negative and 2% false-positive results were reported. Quickly ... ...

    Abstract After a pilot study, we tested 443 cadavers using OraQuick Ebola rapid diagnostic tests during surveillance after the 10th Ebola outbreak in the Democratic Republic of the Congo. No false negative and 2% false-positive results were reported. Quickly returning results and engaging the community enabled timely public health actions.
    Schlagwörter Ebola virus ; rapid diagnostic test ; postmortem surveillance ; Democratic Republic of the Congo ; OraQuik Ebola RDT ; viruses ; Medicine ; R ; Infectious and parasitic diseases ; RC109-216
    Sprache Englisch
    Erscheinungsdatum 2022-02-01T00:00:00Z
    Verlag Centers for Disease Control and Prevention
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel ; Online: Ebola Virus RNA in Semen from an HIV-Positive Survivor of Ebola

    Lawrence J. Purpura / Emerson Rogers / April Baller / Stephen White / Moses Soka / Mary J. Choi / Nuha Mahmoud / Christine Wasunna / Moses Massaquoi / Jomah Kollie / Straker Dweh / Philip Bemah / Victor Ladele / Jonathan Kpaka / Mary Jawara / Margaret Mugisha / Onyekachi Subah / Mylene Faikai / Jeff A. Bailey /
    Pierre E. Rollin / Barbara J. Marston / Tolbert G. Nyenswah / Alex Gasasira / Barbara Knust / Stuart T. Nichol / Desmond Williams

    Emerging Infectious Diseases, Vol 23, Iss 4, Pp 714-

    2017  Band 715

    Abstract: Ebola virus is known to persist in semen of male survivors of Ebola virus disease (EVD). However, maximum duration of, or risk factors for, virus persistence are unknown. We report an EVD survivor with preexisting HIV infection, whose semen was positive ... ...

    Abstract Ebola virus is known to persist in semen of male survivors of Ebola virus disease (EVD). However, maximum duration of, or risk factors for, virus persistence are unknown. We report an EVD survivor with preexisting HIV infection, whose semen was positive for Ebola virus RNA 565 days after recovery from EVD.
    Schlagwörter Ebola virus disease ; Ebola virus ; viruses ; virus RNA ; semen ; HIV ; Medicine ; R ; Infectious and parasitic diseases ; RC109-216
    Sprache Englisch
    Erscheinungsdatum 2017-04-01T00:00:00Z
    Verlag Centers for Disease Control and Prevention
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  7. Artikel ; Online: Prevention of sexual transmission of Ebola in Liberia through a national semen testing and counselling programme for survivors

    Moses J Soka, MD / Dr. Mary J Choi, MD / April Baller, MRCGP / Stephen White, MSc / Emerson Rogers, BSc / Lawrence J Purpura, MD / Nuha Mahmoud, MD / Christine Wasunna, PhD / Moses Massaquoi, MD / Neetu Abad, PhD / Jomah Kollie, RN / Straker Dweh / Philip K Bemah, MD / Athalia Christie, MIA / Victor Ladele, MBBS / Oneychachi C Subah, BSc / Satish Pillai, MD / Margaret Mugisha, MPH / Jonathan Kpaka, BSc /
    Stephen Kowalewski, BS / Emilio German, MSHSA / Mark Stenger, MA / Stuart Nichol, PhD / Ute Ströher, PhD / Kristin E Vanderende, PhD / Shauna Mettee Zarecki, MSN / Hugh Henry W Green, MPH / Jeffrey A Bailey, MD / Pierre Rollin, MD / Barbara Marston, MD / Tolbert G Nyenswah, MPH / Alex Gasasira, MBChB / Barbara Knust, DVM / Desmond Williams, MD

    The Lancet Global Health, Vol 4, Iss 10, Pp e736-e

    an analysis of Ebola virus RNA results and behavioural data

    2016  Band 743

    Abstract: Background: Ebola virus has been detected in semen of Ebola virus disease survivors after recovery. Liberia's Men's Health Screening Program (MHSP) offers Ebola virus disease survivors semen testing for Ebola virus. We present preliminary results and ... ...

    Abstract Background: Ebola virus has been detected in semen of Ebola virus disease survivors after recovery. Liberia's Men's Health Screening Program (MHSP) offers Ebola virus disease survivors semen testing for Ebola virus. We present preliminary results and behavioural outcomes from the first national semen testing programme for Ebola virus. Methods: The MHSP operates out of three locations in Liberia: Redemption Hospital in Montserrado County, Phebe Hospital in Bong County, and Tellewoyan Hospital in Lofa County. Men aged 15 years and older who had an Ebola treatment unit discharge certificate are eligible for inclusion. Participants' semen samples were tested for Ebola virus RNA by real-time RT-PCR and participants received counselling on safe sexual practices. Participants graduated after receiving two consecutive negative semen tests. Counsellors collected information on sociodemographics and sexual behaviours using questionnaires administered at enrolment, follow up, and graduation visits. Because the programme is ongoing, data analysis was restricted to data obtained from July 7, 2015, to May 6, 2016. Findings: As of May 6, 2016, 466 Ebola virus disease survivors had enrolled in the programme; real-time RT-PCR results were available from 429 participants. 38 participants (9%) produced at least one semen specimen that tested positive for Ebola virus RNA. Of these, 24 (63%) provided semen specimens that tested positive 12 months or longer after Ebola virus disease recovery. The longest interval between discharge from an Ebola treatment unit and collection of a positive semen sample was 565 days. Among participants who enrolled and provided specimens more than 90 days since their Ebola treatment unit discharge, men older than 40 years were more likely to have a semen sample test positive than were men aged 40 years or younger (p=0·0004). 84 (74%) of 113 participants who reported not using a condom at enrolment reported using condoms at their first follow-up visit (p<0·0001). 176 (46%) of 385 participants who ...
    Schlagwörter Public aspects of medicine ; RA1-1270
    Sprache Englisch
    Erscheinungsdatum 2016-10-01T00:00:00Z
    Verlag Elsevier
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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