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  1. Article ; Online: Sleep Duration and Daytime Napping and Risk of Type 2 Diabetes Among Japanese Men and Women

    Reiko Okada / Masayuki Teramoto / Isao Muraki / Akiko Tamakoshi / Hiroyasu Iso

    Journal of Epidemiology, Vol 33, Iss 11, Pp 562-

    The Japan Collaborative Cohort Study for Evaluation of Cancer Risk

    2023  Volume 568

    Abstract: Background: Little is known about the impacts of sleep duration and daytime napping on the risk of type 2 diabetes mellitus (T2DM). Methods: In this study, 20,318 participants (7,597 men, 12,721 women) aged 40–79 years without a history of T2DM, stroke, ... ...

    Abstract Background: Little is known about the impacts of sleep duration and daytime napping on the risk of type 2 diabetes mellitus (T2DM). Methods: In this study, 20,318 participants (7,597 men, 12,721 women) aged 40–79 years without a history of T2DM, stroke, coronary heart disease, or cancer at baseline (1988–1990), completed the baseline survey and the 5-year follow-up questionnaires, which included average sleep duration, napping habits, and self-reports of physician-diagnosed diabetes. The multivariable odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using a logistic regression model. Results: During the 5-year follow-up, 531 new cases of T2DM (266 men and 265 women) were documented. Sleep duration ≥10 hours was associated with higher risk of T2DM compared to sleep duration of 7 hours (OR 1.99; 95% CI, 1.28–3.08). The excess risk was observed for both sexes and primarily found among the non-overweight; the multivariable ORs of sleeping ≥10 hours compared to 7 hours were 2.05 (95% CI, 1.26–3.35) for the non-overweight (BMI <25 kg/m2) and 1.38 (95% CI, 0.49–3.83) for the overweight (BMI ≥25 kg/m2). The respective ORs of nappers versus non-nappers were 1.30 (95% CI, 1.03–1.63) and 0.92 (95% CI, 0.65–1.29). Among the non-overweight, nappers who slept ≥10 hours had the highest risk of T2DM (OR 2.84; 95% CI, 1.57–5.14), non-nappers who slept ≥10 hours (OR 2.27; 95% CI, 1.27–4.06), and nappers who slept <10 hours (OR 1.30; 95% CI, 1.03–1.64), compared with non-nappers who slept <10 hours. Conclusion: Long sleep duration was associated with the risk of T2DM in both sexes, which was confined to the non-overweight.
    Keywords sleep duration ; napping ; type 2 diabetes ; cohort study ; Medicine (General) ; R5-920
    Subject code 331
    Language English
    Publishing date 2023-11-01T00:00:00Z
    Publisher Japan Epidemiological Association
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Development of new scores for atherosclerotic cardiovascular disease using specific medical examination items

    Ahmed Arafa / Rena Kashima / Yuka Yasui / Haruna Kawachi / Chisa Matsumoto / Saya Nosaka / Masayuki Teramoto / Miki Matsuo / Yoshihiro Kokubo

    Environmental Health and Preventive Medicine, Vol 28, Pp 61-

    the Suita Study

    2023  Volume 61

    Abstract: Background: We previously developed risk models predicting stroke, coronary heart disease (CHD), and cardiovascular disease (CVD) among Japanese people from the Suita Study. Yet, applying these models at the national level was challenging because some of ...

    Abstract Background: We previously developed risk models predicting stroke, coronary heart disease (CHD), and cardiovascular disease (CVD) among Japanese people from the Suita Study. Yet, applying these models at the national level was challenging because some of the included risk factors differed from those collected in the Japanese governmental health check-ups, such as Tokutei-Kenshin. We, therefore, conducted this study to develop new risk models for stroke, CHD, and atherosclerotic CVD (ASCVD), based on data from the Suita Study. The new models used traditional cardiovascular risk factors similar to those in the Japanese governmental health check-ups. Methods: We included 7,413 participants, aged 30–84 years, initially free from stroke and CHD. All participants received baseline health examinations, including a questionnaire assessing their lifestyle and medical history, medical examination, and blood and urine analysis. The risk factors of stroke, CHD, and ASCVD (cerebral infarction or CHD) were determined using the multivariable-adjusted Cox regression. The models’ performance was assessed using the C-statistics for discrimination and the Hosmer-Lemeshow for calibration. We also developed three simple scores (zero to 100) that could predict the 10-year incidence of stroke, CHD, and ASCVD. Results: Within 110,428 person-years (median follow-up = 16.6 years), 410 stroke events, 288 CHD events, and 527 ASCVD events were diagnosed. Age, smoking, hypertension, and diabetes were associated with stroke, CHD, and ASCVD risk. Men and those with decreased high-density lipoproteins or increased low-density lipoproteins showed a higher risk of CHD and ASCVD. Urinary proteins were associated with an increased risk of stroke and ASCVD. The C-statistic values of the risk models were >0.750 and the p-values of goodness-of-fit were >0.30. The 10-year incidence of stroke, CVD, and ASCVD events was 3.8%, 3.5%, and 5.7% for scores 45–54, 10.3%, 11.8%, and 19.6% for scores 65–74, and 27.7%, 23.5%, and 60.5% for scores ≥85, ...
    Keywords risk scores ; prediction models ; stroke ; coronary heart disease ; Public aspects of medicine ; RA1-1270
    Subject code 310
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher Komiyama Printing Co. Ltd
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: The Lifelong Health Support 10

    Ahmed Arafa / Yoshihiro Kokubo / Rena Kashima / Masayuki Teramoto / Yukie Sakai / Saya Nosaka / Youko M. Nakao / Emi Watanabe

    Environmental Health and Preventive Medicine, Vol 27, Iss 0, Pp 23-

    a Japanese prescription for a long and healthy life

    2022  Volume 23

    Abstract: Background: Although the age-adjusted incidence and mortality of cancer and cardiovascular disease (CVD) have been decreasing steadily in Japan, both diseases remain major contributors to morbidity and mortality along with the aging society. Herein, we ... ...

    Abstract Background: Although the age-adjusted incidence and mortality of cancer and cardiovascular disease (CVD) have been decreasing steadily in Japan, both diseases remain major contributors to morbidity and mortality along with the aging society. Herein, we aim to provide a prescription of 10 health tips for long and healthy life named the “Lifelong Health Support 10 (LHS10).” Method: The LHS10 was developed by the preventive medicine specialists at the National Cerebral and Cardiovascular Center in Suita, where it has been used for health guidance to prevent CVD, cancer, and cognitive decline in addition to their major risk factors such as hypertension, diabetes, and obesity. It consisted of the lifestyle modification recommendations of the 2014 Japanese Society of Hypertension guidelines and the 2017 Japan Atherosclerosis Society Guidelines for preventing atherosclerotic CVD. Further, it came in line with other international lifestyle modification guidelines. In this narrative review, we summarized the results of several Japanese epidemiological studies investigating the association between the LHS10 items and the risk of cancer, CVD, and other chronic diseases including dementia, diabetes, and chronic kidney disease. Results: The LHS10 included avoiding smoking and secondhand smoke exposure, engaging in physical activity, refraining from excessive alcohol drinking, reducing fried foods and sugary soft drinks, cutting salt in food, consuming more vegetables, fruits, fish, soy foods, and fibers, and maintaining proper body weight. All items of the LHS10 were shown to reduce the risk of cancer, CVD, and other chronic diseases. Conclusions: The LHS10 can be a helpful tool for health guidance.
    Keywords lifelong health support 10 ; cancer ; cardiovascular diseases ; lifestyle ; japan ; Public aspects of medicine ; RA1-1270
    Subject code 610
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher Komiyama Printing Co. Ltd
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Alcohol consumption and the risk of heart failure

    Ahmed Arafa / Rena Kashima / Yoshihiro Kokubo / Masayuki Teramoto / Yukie Sakai / Saya Nosaka / Haruna Kawachi / Keiko Shimamoto / Chisa Matsumoto / Qi Gao / Chisato Izumi

    Environmental Health and Preventive Medicine, Vol 28, Pp 26-

    the Suita Study and meta-analysis of prospective cohort studies

    2023  Volume 26

    Abstract: Background: Alcohol consumption is a modifiable lifestyle, but its role in heart failure (HF) development is controversial. Herein, we investigated the prospective association between alcohol consumption and HF risk. Methods: A total of 2,712 ... ...

    Abstract Background: Alcohol consumption is a modifiable lifestyle, but its role in heart failure (HF) development is controversial. Herein, we investigated the prospective association between alcohol consumption and HF risk. Methods: A total of 2,712 participants (1,149 men and 1,563 women) from the Suita Study were followed up every two years. Cox regression was applied to calculate the hazard ratios (HRs) and 95% confidence intervals (95% CIs) of HF risk for heavy drinking (≥46 g/day in men or ≥23 g/day in women) and never drinking compared to light drinking (<23 g/day in men or <11.5 g/day in women). Then, we combined the results of the Suita Study with those from other eligible prospective cohort studies in a meta-analysis using the random-effects model. Results: In the Suita Study, within a median follow-up period of 8 years, 319 HF cases (162 in men and 157 in women) were detected. In men, but not women, never and heavy drinking carried a higher risk of HF than light drinking: HRs (95% CIs) = 1.65 (1.00, 2.73) and 2.14 (1.26, 3.66), respectively. Alike, the meta-analysis showed a higher risk of HF among heavy drinkers: HR (95% CI) = 1.37 (1.15, 1.62) and abstainers: HR (95% CI) = 1.18 (1.02, 1.37). Conclusion: We indicated a J-shaped association between alcohol consumption and HF risk among Japanese men. The results of the meta-analysis came in line with the Suita Study. Heavy-drinking men should be targeted for lifestyle modification interventions.
    Keywords alcohol consumption ; heart failure ; prospective cohort ; japan ; meta-analysis ; Public aspects of medicine ; RA1-1270
    Subject code 310
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher Komiyama Printing Co. Ltd
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Stair climbing and incident atrial fibrillation

    Ahmed Arafa / Yoshihiro Kokubo / Keiko Shimamoto / Rena Kashima / Emi Watanabe / Yukie Sakai / Jiaqi Li / Masayuki Teramoto / Haytham A. Sheerah / Kengo Kusano

    Environmental Health and Preventive Medicine, Vol 27, Iss 0, Pp 10-

    a prospective cohort study

    2022  Volume 10

    Abstract: Background: A protective role for physical activity against the development of atrial fibrillation (AF) has been suggested. Stair climbing is a readily available form of physical activity that many people practice. Herein, we investigated the association ...

    Abstract Background: A protective role for physical activity against the development of atrial fibrillation (AF) has been suggested. Stair climbing is a readily available form of physical activity that many people practice. Herein, we investigated the association between stair climbing and the risk of AF in a Japanese population. Methods: In this prospective cohort study, we used data of 6,575 people registered in the Suita Study, aged 30–84 years, and had no history of AF. The frequency of stair climbing was assessed by a baseline questionnaire, while AF was diagnosed during the follow-up using a 12-lead ECG, health records, check-ups, and death certificates. We used the Cox regression to calculate the hazard ratios and 95% confidence intervals of AF incidence for climbing stairs in 20–39%, 40–59%, and ≥60% compared with <20% of the time. Results: Within 91,389 person-years of follow-up, 295 participants developed AF. The incidence of AF was distributed across the stair climbing groups <20%, 20–39%, 40–59%, and ≥60% as follows: 3.57, 3.27, 3.46, and 2.63/1,000 person-years, respectively. Stair climbing ≥60% of the time was associated with a reduced risk of AF after adjustment for age and sex 0.69 (0.49, 0.96). Further adjustment for lifestyle and medical history did not affect the results 0.69 (0.49, 0.98). Conclusion: Frequent stair climbing could protect from AF. From a preventive point of view, stair climbing could be a simple way to reduce AF risk at the population level.
    Keywords stair climbing ; atrial fibrillation ; prospective studies ; japan ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher Komiyama Printing Co. Ltd
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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