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  1. Article ; Online: Dynamic Contrast-enhanced MRI Demonstrates Pulmonary Microvascular Abnormalities Months After SARS-CoV-2 Infection.

    Zhou, Iris Y / Mascia, Molly / Alba, George A / Magaletta, Michael / Ginns, Leo C / Caravan, Peter / Montesi, Sydney B

    American journal of respiratory and critical care medicine

    2023  Volume 207, Issue 12, Page(s) 1636–1639

    MeSH term(s) Humans ; COVID-19 ; SARS-CoV-2 ; Magnetic Resonance Imaging
    Language English
    Publishing date 2023-04-23
    Publishing country United States
    Document type Letter ; Research Support, N.I.H., Extramural
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202210-1884LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Plasma NEDD9 is increased following SARS-CoV-2 infection and associates with indices of pulmonary vascular dysfunction.

    Alba, George A / Zhou, Iris Y / Mascia, Molly / Magaletta, Michael / Alladina, Jehan W / Giacona, Francesca L / Ginns, Leo C / Caravan, Peter / Maron, Bradley A / Montesi, Sydney B

    Pulmonary circulation

    2024  Volume 14, Issue 1, Page(s) e12356

    Abstract: Compared to healthy volunteers, participants with post-acute sequelae of SARS-CoV-2 infection (PASC) demonstrated increased plasma levels of the prothrombotic protein NEDD9, which associated inversely with indices of pulmonary vascular function. This ... ...

    Abstract Compared to healthy volunteers, participants with post-acute sequelae of SARS-CoV-2 infection (PASC) demonstrated increased plasma levels of the prothrombotic protein NEDD9, which associated inversely with indices of pulmonary vascular function. This suggests persistent pulmonary vascular dysfunction may play a role in the pathobiology of PASC.
    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2638089-4
    ISSN 2045-8940 ; 2045-8932
    ISSN (online) 2045-8940
    ISSN 2045-8932
    DOI 10.1002/pul2.12356
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A Phase 3, Open-Label Study of Lumacaftor/Ivacaftor in Children 1 to Less Than 2 Years of Age with Cystic Fibrosis Homozygous for

    Rayment, Jonathan H / Asfour, Fadi / Rosenfeld, Margaret / Higgins, Mark / Liu, Lingyun / Mascia, Molly / Paz-Diaz, Hildegarde / Tian, Simon / Zahigian, Rachel / McColley, Susanna A

    American journal of respiratory and critical care medicine

    2022  Volume 206, Issue 10, Page(s) 1239–1247

    Abstract: Rationale: ...

    Abstract Rationale:
    MeSH term(s) Humans ; Aminophenols ; Aminopyridines ; Benzodioxoles ; Chloride Channel Agonists/therapeutic use ; Chlorides/analysis ; Cystic Fibrosis/drug therapy ; Cystic Fibrosis/genetics ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Cystic Fibrosis Transmembrane Conductance Regulator/therapeutic use ; Drug Combinations ; Forced Expiratory Volume ; Mutation ; Infant
    Chemical Substances Aminophenols ; Aminopyridines ; Benzodioxoles ; CFTR protein, human ; Chloride Channel Agonists ; Chlorides ; Cystic Fibrosis Transmembrane Conductance Regulator (126880-72-6) ; Drug Combinations ; ivacaftor (1Y740ILL1Z) ; lumacaftor (EGP8L81APK)
    Language English
    Publishing date 2022-06-30
    Publishing country United States
    Document type Clinical Trial, Phase III ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202204-0734OC
    Database MEDical Literature Analysis and Retrieval System OnLINE

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