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Article ; Online: Identification and management of subvesical bile duct leakage after laparoscopic cholecystectomy: A systematic review.

Carannante, F / Mazzotta, E / Miacci, V / Bianco, G / Mascianà, G / D'Agostino, F / Caricato, M / Capolupo, G T

2023 Volume 46, Issue 10, Page(s) 4161–4168

Abstract: Bile leak is a rare complication after Laparoscopic Cholecystectomy. Subvesical bile duct (SVBD) injury is the second cause of minor bile leak, following the unsuccessful clipping of the cystic duct stump. The aim of this study is to pool available data ... ...

Abstract	Bile leak is a rare complication after Laparoscopic Cholecystectomy. Subvesical bile duct (SVBD) injury is the second cause of minor bile leak, following the unsuccessful clipping of the cystic duct stump. The aim of this study is to pool available data on this type of biliary tree anatomical variation to summarize incidence of injury, methods used to diagnose and treat SVBD leaks after LC. Articles published between 1985 and 2021 describing SVBD evidence in patients operated on LC for gallstone disease, were included. Data were divided into two groups based on the intra or post-operative evidence of bile leak from SVBD after surgery. This systematic report includes 68 articles for a total of 231 patients. A total of 195 patients with symptomatic postoperative bile leak are included in Group 1, while Group 2 includes 36 patients describing SVBD visualized and managed during LC. Outcomes of interest were diagnosis, clinical presentation, treatment, and outcomes. The management of minor bile leak is controversial. In most of cases diagnosed postoperatevely, Endoscopic Retrograde Cholangio-Pancreatography (ERCP) is the best way to treat this complication. Surgery should be considered when endoscopic or radiological approaches are not resolutive.
MeSH term(s)	Humans ; Cholecystectomy, Laparoscopic/adverse effects ; Postoperative Complications/diagnosis ; Postoperative Complications/etiology ; Postoperative Complications/surgery ; Cholangiopancreatography, Endoscopic Retrograde/methods ; Bile Ducts/surgery ; Bile Ducts/injuries ; Bile Duct Diseases/surgery ; Biliary Tract Diseases/complications
Language	English
Publishing date	2023-04-29
Publishing country	Netherlands
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	1068461-x
ISSN	0219-3108 ; 1015-9584
ISSN (online)	0219-3108
ISSN	1015-9584
DOI	10.1016/j.asjsur.2023.04.031
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Article: TaTME approach as a rescue during a laparoscopic TME for high rectal cancer. A case report.

Carannante, F / Bianco, G / Lauricella, S / Mascianà, G / Caricato, M / Capolupo, G T

International journal of surgery case reports

2021 Volume 82, Page(s) 105870

Abstract: Introduction and importance: In the last years, transanal total mesorectal excision (TaTME) has been described in rectal cancer treatment, especially in challenging patients, difficulties in pelvic exposure and limitations of instrumentation improving ... ...

Abstract	Introduction and importance: In the last years, transanal total mesorectal excision (TaTME) has been described in rectal cancer treatment, especially in challenging patients, difficulties in pelvic exposure and limitations of instrumentation improving not only dissection but also the preservation of autonomic pelvic nerves and the achievement of a restorative procedure. Here we report a case report of anterior laparoscopic rectal resection for adenocarcinoma of the high-mid rectum converted to transanal approach. Case presentation: A 69-year-old male presented hepatic nodules during radiological follow-up for prostate cancer treated with radical prostatectomy and adjuvant radiotherapy (70 Gy). The biopsy of the lesion demonstrated the presence of a metastatic lesion of an adenocarcinoma, with suspected intestinal origin. Then, we perform an endoscopic examination, which showed the presence of a rectal lesion, which cause a bowel stenosis extended from the middle part to the upper part of the rectum. After chemoradiotherapy, an anterior rectal resection was performed. During surgery we could not perform the resection of the rectum due the thickness and fibrosis of the tissue, despite we used different branded mechanical stapler. So, we decided to complete the surgical treatment starting a TaTME procedure with resolution of the problem. Clinical discussion: TaTME is a relatively new technique that had already become a valid option in the treatment of low rectal cancer, and, nowadays, also in the treatment of inflammatory bowel disease. As reported in literature, this technique has a number of advantages, especially in narrow pelvis and it is very useful in low rectal surgery. Conclusion: This case report aims to describe the possible use of TaTME procedure as a rescue also when this approach is not the first choice.
Language	English
Publishing date	2021-04-07
Publishing country	Netherlands
Document type	Journal Article
ISSN	2210-2612
ISSN	2210-2612
DOI	10.1016/j.ijscr.2021.105870
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Article ; Online: Transanal proctocolectomy and ileal pouch-anal anastomosis (TaIPAA) for ulcerative colitis: medium term functional outcomes in a single centre.

Capolupo, G T / Carannante, F / Mascianà, G / Lauricella, S / Mazzotta, E / Caricato, M

BMC surgery

2021 Volume 21, Issue 1, Page(s) 17

Abstract: Background: Transanal dissection of the rectum has been recently introduced for ileal pouch-anal anastomosis (IPAA) in UC showing promising results. Thanks to the precise identification of the rectotomy site the risk of long rectal stump is avoided, and ...

Abstract	Background: Transanal dissection of the rectum has been recently introduced for ileal pouch-anal anastomosis (IPAA) in UC showing promising results. Thanks to the precise identification of the rectotomy site the risk of long rectal stump is avoided, and a single stapled anastomosis is performed easily. The aim of this study is to analyze our initial experience of transanal proctocolectomy and ileal pouch-anal anastomosis (TaIPAA), considering postoperative complications and medium-term functional outcomes. Methods: Our Center has experienced the transanal approach for proctectomy and IPAA since August 2018. All patients underwent Enhanced Recovery After Surgery (ERAS) protocol. Postoperative complications occurring within 30 days after surgery were taken into consideration. Fecal continence, genito-urinary activity and global quality of life at 1 and 6 months after ileostomy reversal have been assessed. Results: Until March 2019, 8 patients underwent transanal proctocolectomy and ileal pouch-anal anastomosis (TaIPAA). In all cases the laparoscopic approach was performed during the transabdominal phase; abdominal drainage was never used. At the time of the pouch construction a defunctioning loop ileostomy was created in all patients. Stoma closure was performed in all cases at a median time of 6 months after surgery. Postoperative complications occurred in only one patient, who showed rectal bleeding, not required a re-invertation. There were no cases of anastomotic leakage. Medium-term functional outcomes were determined prospectively using previously validated quality of life questionnaires (Cleveland Global Quality of Life). Fecal incontinence for liquid or solid stool, genitourinary and sexual functions were also investigated, showing comparable results with the literature data. Conclusions: In our experience, transanal proctocolectomy and ileal pouch-anal anastomosis provided good short and medium-term functional results in UC.
MeSH term(s)	Adult ; Aged ; Anal Canal/surgery ; Anastomosis, Surgical ; Colitis, Ulcerative/surgery ; Female ; Humans ; Ileum/surgery ; Male ; Middle Aged ; Postoperative Complications/epidemiology ; Proctocolectomy, Restorative ; Quality of Life ; Treatment Outcome
Language	English
Publishing date	2021-01-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2050442-1
ISSN	1471-2482 ; 1471-2482
ISSN (online)	1471-2482
ISSN	1471-2482
DOI	10.1186/s12893-020-01007-z
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Article ; Online: Comparison of purse-string technique vs linear suture for skin closure after ileostomy reversal. A randomized controlled trial.

Carannante, Filippo / Costa, Gianluca / Miacci, Valentina / Bianco, Gianfranco / Masciana, Gianluca / Lauricella, Sara / Caricato, Marco / Capolupo, Gabriella Teresa

Langenbeck's archives of surgery

2024 Volume 409, Issue 1, Page(s) 141

Abstract: Background: Protective stoma after rectal surgery has been associated with important complications. The most common is surgical site infection (SSI) high rates after stoma reversal reported in literature. Our study compared the rate of SSI of two skin ... ...

Abstract	Background: Protective stoma after rectal surgery has been associated with important complications. The most common is surgical site infection (SSI) high rates after stoma reversal reported in literature. Our study compared the rate of SSI of two skin closure techniques, linear closure, and purse string closure. Methods: We carried out a single center, prospective, randomized controlled trial in the Department of Colorectal Surgery of Fondazione Policlinico Campus Bio-Medico of Rome between January 2018 through December 2021, to compare LC vs PS closure of ileostomy sites. Results: A total of 117 patients (53.84% male) with a mean age of 65.68 ± 14.33 years were finally evaluated in the study. 58 patients were included in the PS group and 59 patients in the LC one. There was a marked difference in the SSI rate between the two arms of the study: 3 of 58 patients in the purse-string arm versus 11 of 59 in the control arm (p = 0.043). The outcome of cosmesis was also higher in PS, with a statistical significance (mean ± DS 4,01 ± 0,73 for PS group vs mean ± DS 2,38 ± 0,72 for LC group, p < 0,001). Conclusion: Our study demonstrated that the PS technique had a significantly lower incidence of stoma site SSI compared with LC technique. Our findings are in line with other randomized studies and suggest that PS closure could be considered as standard of care for wound closure after ileostomy reversal.
MeSH term(s)	Humans ; Ileostomy/adverse effects ; Ileostomy/methods ; Male ; Female ; Aged ; Surgical Wound Infection/prevention & control ; Surgical Wound Infection/epidemiology ; Prospective Studies ; Middle Aged ; Suture Techniques ; Reoperation ; Wound Closure Techniques
Language	English
Publishing date	2024-04-27
Publishing country	Germany
Document type	Journal Article ; Randomized Controlled Trial ; Comparative Study
ZDB-ID	1423681-3
ISSN	1435-2451 ; 1435-2443
ISSN (online)	1435-2451
ISSN	1435-2443
DOI	10.1007/s00423-024-03332-w
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Article: An omental mass. Any idea?

Mascianà, G / Capolupo, G T / Carannante, F / Caricato, M

International journal of surgery case reports

2019 Volume 56, Page(s) 40–44

Abstract: Introduction: Pseudomyxoma extraperitonei (PE) is a rare finding. The most common cause is the rupture of a mucocele of the appendix into the retroperitoneum.: Presentation of case: Here we report a case of a 52 years old female patient with a mass ... ...

Abstract	Introduction: Pseudomyxoma extraperitonei (PE) is a rare finding. The most common cause is the rupture of a mucocele of the appendix into the retroperitoneum. Presentation of case: Here we report a case of a 52 years old female patient with a mass in the right abdomen and vague lower abdominal pain underwent resection of a extraperitoneal encapsulated mass. The histopathological examination revealed a mucinous pseudomyxoma with a low grade of differentiation. Discussion: We report a case of pseudomyxoma extraperitonei with a review of literature. Conclusion: The treatment of pseudomyxoma differs substantially depending on whether it is intraperitoneal or extraperitoneal. The risk of recurrence is such that follow-up, based on a physical examination, CT scan and serum markers, is essential.
Language	English
Publishing date	2019-02-15
Publishing country	Netherlands
Document type	Journal Article
ISSN	2210-2612
ISSN	2210-2612
DOI	10.1016/j.ijscr.2019.02.019
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Article: Hepatic portal venous gas after colonoscopy: A case report and review.

Capolupo, G T / Mascianà, G / Carannante, F / Caricato, M

International journal of surgery case reports

2018 Volume 51, Page(s) 54–57

Abstract: Introduction: Hepatic portal venous gas (HPVG) is a rare radiological finding in which gas enters the portal venous system and it is associated in case of necrotizing colitis with a mortality of 75%. We report a case of iatrogenic HPVG with a review of ... ...

Abstract	Introduction: Hepatic portal venous gas (HPVG) is a rare radiological finding in which gas enters the portal venous system and it is associated in case of necrotizing colitis with a mortality of 75%. We report a case of iatrogenic HPVG with a review of literature. Presentation of case: A 41 years old patient underwent total colectomy and ileal pouch- anal anastomosis with derivative ileostomy for a familiar adenomatous polyposis coli in June 2008. A stenosis of the pouch-anal anastomosis developed. The patient underwent several endoscopic dilations. A recurrence of the stenosis was observed. The patient underwent to several endoscopic procedure. After the last colonoscopy the patient showed a fever with abdominal pain. A CT scan showed little peri-anastomotic collections and massive hepatic portal venous gas. Discussion: The management of HPVG varied from surgical intervention to non-operative procedure. The surgical approach it's reserved to clinically unstable patients or those with evidence of peritonitis or bowel perforation. Stable patients, like those with an HPVG consequence of an endoscopic procedure, can be treated with non- operative management. Conclusion: Our experience confirm that hepatic portal venous gas can be related to endoscopic procedure; thus, it can be managed on the basis of patient's general clinical conditions, and in selected cases it will disappear without therapeutic interventions with a good outcome.
Language	English
Publishing date	2018-07-21
Publishing country	Netherlands
Document type	Journal Article
ISSN	2210-2612
ISSN	2210-2612
DOI	10.1016/j.ijscr.2018.06.041
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Article: Spilled gallstones simulating peritoneal carcinomatosis: A case report and literature review.

Capolupo, G T / Mascianà, G / Carannante, F / Caricato, M

International journal of surgery case reports

2018 Volume 48, Page(s) 113–121

Abstract: Introduction: Laparoscopic cholecystectomy (LC) has become the "gold standard" for the treatment of symptomatic gallstones. However, this surgical technique increases the risk of bile duct injury and lost gallstones. Since over 90% of split gallstones ... ...

Abstract	Introduction: Laparoscopic cholecystectomy (LC) has become the "gold standard" for the treatment of symptomatic gallstones. However, this surgical technique increases the risk of bile duct injury and lost gallstones. Since over 90% of split gallstones never become symptomatic, they often present as incidental findings on CT-scans. Careful removal of as many stones as possible, intense irrigation and suction are recommended. It has been reported that 8.5% of lost gallstones will lead to a complication, most common are abscesses. Presentation case: We report a case of spilled gallstones simulating peritoneal metastases on radiological investigations. Diagnosis was very difficult, not even an US-guided biopsy of the lesion was decisive. Only a diagnostic laparoscopy confirms the diagnosis. Discussion: The reaction associated with lost gallstones can mimic other causes, such as soft tissue sarcoma, malignant lymphoma or, as in our case peritoneal carcinomatosis. Conclusion: Spilled gallstones are associated with uncommon, but significant complications, and even the diagnosis of such a condition can cause serious difficulties. Serious effort must be made to prevent gallbladder perforation, and accidental stone spillage should be promptly recognized and properly managed.
Language	English
Publishing date	2018-05-04
Publishing country	Netherlands
Document type	Journal Article
ISSN	2210-2612
ISSN	2210-2612
DOI	10.1016/j.ijscr.2018.04.016
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Article ; Online: Cost-effectiveness analysis of O-Ring wound retractor in elective laparoscopic colorectal surgery.

Lauricella, Sara / Caricato, Marco / Mascianà, Gianluca / Ciccozzi, Massimo / Angeletti, Silvia / Capolupo, Gabriella Teresa

Annali italiani di chirurgia

2022 Volume 92, Page(s) 460–464

Abstract: Introduction: Surgical site infections (SSIs) are a feared complication following colorectal surgery and have a sizeable economic impact on the healthcare system. The aim of this study is to assess the clinical effectiveness and cost-effectiveness of O- ... ...

Abstract	Introduction: Surgical site infections (SSIs) are a feared complication following colorectal surgery and have a sizeable economic impact on the healthcare system. The aim of this study is to assess the clinical effectiveness and cost-effectiveness of O-Ring wound protector/retractor in elective laparoscopic colorectal surgery. Methods: Data were analyzed from a retrospective colorectal database from January 2015 to June 2018. SSI was defined according to the criteria published by the European Centre for Disease Prevention and Control (ECDC). An economic evaluation was conducted comparing the group in which Alexis® device was used during surgery (Group A) with a control group (Group B) in which Alexis® device was not used. Results: Two hundred fifty-eight consecutive patients were enrolled in our study. Among them, the intervention group (Group A, 154 patients) was compared with the control group (Group B, 94 patients). A total of 8 (5.2%) and 14 (15%) patients with SSIs were identified in groups A and B, respectively (p = 0.008). The economic evaluation showed that there was no difference in terms of costs and returns on comparing both groups. Conclusion: The final costs and profit are similar in both groups, but the use of O-Ring protector reduces SSI rates and may significantly improve patient's quality of life. Key words: Colorectal surgery, Cost-effectiveness, Surgical site infection, Length of stay, Wound protector/retractor.
MeSH term(s)	Colorectal Surgery ; Cost-Benefit Analysis ; Humans ; Laparoscopy ; Quality of Life ; Retrospective Studies ; Surgical Wound Infection/epidemiology ; Surgical Wound Infection/prevention & control
Language	English
Publishing date	2022-05-01
Publishing country	Italy
Document type	Journal Article
ZDB-ID	418927-9
ISSN	2239-253X ; 0003-469X
ISSN (online)	2239-253X
ISSN	0003-469X
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Article: Hepatic Portal Venous Gas and Anastomotic Leakage.

Carannante, Filippo / Capolupo, Gabriella Teresa / Mascianà, Gianluca / Caricato, Marco

Annals of coloproctology

2020 Volume 36, Issue 4, Page(s) 211

Language	English
Publishing date	2020-08-31
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2711906-3
ISSN	2287-9722 ; 2287-9714
ISSN (online)	2287-9722
ISSN	2287-9714
DOI	10.3393/ac.2019.06.13
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Article ; Online: Intramesorectal or total mesorectal excision for ulcerative colitis: what is better for the patient?

Carannante, Filippo / Mazzotta, Erica / Mascianà, Gianluca / Caricato, Marco / Capolupo, Gabriella

Minerva chirurgica

2020 Volume 75, Issue 6, Page(s) 470–471

MeSH term(s)	Colitis, Ulcerative/surgery ; Fascia ; Humans ; Organ Sparing Treatments/methods ; Pelvis/innervation ; Proctocolectomy, Restorative/methods ; Rectum/surgery ; Urethra/injuries
Language	English
Publishing date	2020-09-25
Publishing country	Italy
Document type	Letter
ZDB-ID	123603-9
ISSN	1827-1626 ; 0026-4733
ISSN (online)	1827-1626
ISSN	0026-4733
DOI	10.23736/S0026-4733.20.08479-5
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